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5,10-methenyltetrahydrofolate + FADH2
5,10-methylene tetrahydrofolate + FAD
-
-
-
-
?
epsilon-N-methyl-L-lysine + acceptor + H2O
formaldehyde + L-lysine + reduced acceptor
-
-
-
?
N,N-dimethylglycine + 5,6,7,8-tetrahydrofolate + electron-transfer flavoprotein
sarcosine + 5,10-methylenetetrahydrofolate + reduced electron-transfer flavoprotein
N,N-dimethylglycine + acceptor + H2O
sarcosine + formaldehyde + reduced acceptor
N,N-dimethylglycine + electron-transfer flavoprotein + H2O
sarcosine + formaldehyde + reduced electron-transfer flavoprotein
N,N-dimethylglycine + electron-transfer flavoprotein + H2O
sarcosine + formaldehyde + reduced electron-transfer flavoprotein + H2O2
N,N-dimethylglycine + FAD + H2O
sarcosine + formaldehyde + FADH2
-
-
-
?
N,N-dimethylglycine + ferricenium + H2O
sarcosine + formaldehyde + ferrocene
-
-
-
?
N,N-dimethylglycine + ferricenium hexafluorophosphate + H2O
sarcosine + formaldehyde + reduced ferricenium hexafluorophosphate
-
-
-
-
?
N,N-dimethylglycine + H2O + FAD
sarcosine + formaldehyde + FADH2
-
-
-
-
?
N,N-dimethylglycine + H2O + ferrocene
sarcosine + formaldehyde + ?
-
-
-
?
N,N-dimethylglycine + H2O + oxidized 1-methoxy-5-methylphenazinium methylsulfate
sarcosine + formaldehyde + reduced 1-methoxy-5-methylphenazinium methylsulfate
-
-
-
-
?
N,N-dimethylglycine + H2O + oxidized 2,6-dichlorophenolindophenol
sarcosine + formaldehyde + reduced 2,6-dichlorophenolindophenol
N,N-dimethylglycine + oxidized ferricenium hexafluorophosphate + H2O
sarcosine + formaldehyde + reduced ferricenium hexafluorophosphate + H2O2
-
-
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
N-methyl-L-alanine + acceptor + H2O
formaldehyde + L-alanine + reduced acceptor
-
-
-
?
sarcosine + acceptor + H2O
glycine + formaldehyde + reduced acceptor
-
-
-
?
sarcosine + electron-transfer flavoprotein + H2O
glycine + formaldehyde + reduced electron-transfer flavoprotein + H2O2
N,N-dimethylglycine + 5,6,7,8-tetrahydrofolate + electron-transfer flavoprotein
sarcosine + 5,10-methylenetetrahydrofolate + reduced electron-transfer flavoprotein
the enzyme takes part in choline degradation, one-carbon metabolism and electron transfer to the respiratory chain
-
-
?
N,N-dimethylglycine + 5,6,7,8-tetrahydrofolate + electron-transfer flavoprotein
sarcosine + 5,10-methylenetetrahydrofolate + reduced electron-transfer flavoprotein
ferrocene or 2,6-dichlorophenolindophenol are used as artificial electron acceptor
-
-
?
N,N-dimethylglycine + acceptor + H2O
sarcosine + formaldehyde + reduced acceptor
-
acceptors: 2,6-dichlorophenolindophenol, phenazine methosulfate
-
?
N,N-dimethylglycine + acceptor + H2O
sarcosine + formaldehyde + reduced acceptor
-
-
-
?
N,N-dimethylglycine + acceptor + H2O
sarcosine + formaldehyde + reduced acceptor
-
acceptors: 2,6-dichlorophenolindophenol, phenazine methosulfate
-
?
N,N-dimethylglycine + acceptor + H2O
sarcosine + formaldehyde + reduced acceptor
-
acceptors: 2,6-dichlorophenolindophenol, phenazine methosulfate
-
?
N,N-dimethylglycine + acceptor + H2O
sarcosine + formaldehyde + reduced acceptor
-
acceptors: 2,6-dichlorophenolindophenol, phenazine methosulfate
-
?
N,N-dimethylglycine + acceptor + H2O
sarcosine + formaldehyde + reduced acceptor
-
acceptors: 2,6-dichlorophenolindophenol, phenazine methosulfate
-
?
N,N-dimethylglycine + acceptor + H2O
sarcosine + formaldehyde + reduced acceptor
-
acceptors: 2,6-dichlorophenolindophenol, phenazine methosulfate
-
?
N,N-dimethylglycine + acceptor + H2O
sarcosine + formaldehyde + reduced acceptor
-
acceptors: 2,6-dichlorophenolindophenol, phenazine methosulfate
-
?
N,N-dimethylglycine + acceptor + H2O
sarcosine + formaldehyde + reduced acceptor
-
acceptors: 2,6-dichlorophenolindophenol, phenazine methosulfate
-
?
N,N-dimethylglycine + acceptor + H2O
sarcosine + formaldehyde + reduced acceptor
-
acceptors: 2,6-dichlorophenolindophenol, phenazine methosulfate
-
?
N,N-dimethylglycine + acceptor + H2O
sarcosine + formaldehyde + reduced acceptor
-
acceptors: 2,6-dichlorophenolindophenol, phenazine methosulfate
-
?
N,N-dimethylglycine + acceptor + H2O
sarcosine + formaldehyde + reduced acceptor
-
bound tetrahydrofolate interacts directly with the enzyme and serves as an acceptor for the one-carbon unit produced during the oxidative demethylation of dimethylglycine
-
?
N,N-dimethylglycine + acceptor + H2O
sarcosine + formaldehyde + reduced acceptor
-
acceptors: 2,6-dichlorophenolindophenol, phenazine methosulfate
-
?
N,N-dimethylglycine + acceptor + H2O
sarcosine + formaldehyde + reduced acceptor
-
acceptors: 2,6-dichlorophenolindophenol, phenazine methosulfate
-
?
N,N-dimethylglycine + electron-transfer flavoprotein + H2O
sarcosine + formaldehyde + reduced electron-transfer flavoprotein
-
-
-
?
N,N-dimethylglycine + electron-transfer flavoprotein + H2O
sarcosine + formaldehyde + reduced electron-transfer flavoprotein
-
-
-
?
N,N-dimethylglycine + electron-transfer flavoprotein + H2O
sarcosine + formaldehyde + reduced electron-transfer flavoprotein + H2O2
-
-
-
r
N,N-dimethylglycine + electron-transfer flavoprotein + H2O
sarcosine + formaldehyde + reduced electron-transfer flavoprotein + H2O2
-
-
-
r
N,N-dimethylglycine + H2O + oxidized 2,6-dichlorophenolindophenol
sarcosine + formaldehyde + reduced 2,6-dichlorophenolindophenol
-
-
-
?
N,N-dimethylglycine + H2O + oxidized 2,6-dichlorophenolindophenol
sarcosine + formaldehyde + reduced 2,6-dichlorophenolindophenol
-
-
-
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
during the reaction tightly bound tetrahydropteroylpentaglutamate is converted to 5,10-methylene tetrahydropteroylpentaglutamate
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
during the reaction tightly bound tetrahydropteroylpentaglutamate is converted to 5,10-methylene tetrahydropteroylpentaglutamate
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
during the reaction tightly bound tetrahydropteroylpentaglutamate is converted to 5,10-methylene tetrahydropteroylpentaglutamate
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
during the reaction tightly bound tetrahydropteroylpentaglutamate is converted to 5,10-methylene tetrahydropteroylpentaglutamate
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
reaction of the choline degradation pathway
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
reaction of the choline degradation pathway
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
reaction of the choline degradation pathway
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
reaction of the choline degradation pathway
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
reaction of the choline degradation pathway
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
reaction of the choline degradation pathway
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
reaction of the choline degradation pathway
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
tetrahydropteroylpentaglutamate is used in vivo as an acceptor of the one-carbon group generated during the reaction
-
?
sarcosine + electron-transfer flavoprotein + H2O
glycine + formaldehyde + reduced electron-transfer flavoprotein + H2O2
-
-
-
r
sarcosine + electron-transfer flavoprotein + H2O
glycine + formaldehyde + reduced electron-transfer flavoprotein + H2O2
-
-
-
r
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5,10-methenyltetrahydrofolate + FADH2
5,10-methylene tetrahydrofolate + FAD
-
-
-
-
?
N,N-dimethylglycine + 5,6,7,8-tetrahydrofolate + electron-transfer flavoprotein
sarcosine + 5,10-methylenetetrahydrofolate + reduced electron-transfer flavoprotein
the enzyme takes part in choline degradation, one-carbon metabolism and electron transfer to the respiratory chain
-
-
?
N,N-dimethylglycine + electron-transfer flavoprotein + H2O
sarcosine + formaldehyde + reduced electron-transfer flavoprotein
N,N-dimethylglycine + FAD + H2O
sarcosine + formaldehyde + FADH2
-
-
-
?
N,N-dimethylglycine + H2O + FAD
sarcosine + formaldehyde + FADH2
-
-
-
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
N,N-dimethylglycine + electron-transfer flavoprotein + H2O
sarcosine + formaldehyde + reduced electron-transfer flavoprotein
-
-
-
?
N,N-dimethylglycine + electron-transfer flavoprotein + H2O
sarcosine + formaldehyde + reduced electron-transfer flavoprotein
-
-
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
during the reaction tightly bound tetrahydropteroylpentaglutamate is converted to 5,10-methylene tetrahydropteroylpentaglutamate
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
during the reaction tightly bound tetrahydropteroylpentaglutamate is converted to 5,10-methylene tetrahydropteroylpentaglutamate
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
during the reaction tightly bound tetrahydropteroylpentaglutamate is converted to 5,10-methylene tetrahydropteroylpentaglutamate
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
during the reaction tightly bound tetrahydropteroylpentaglutamate is converted to 5,10-methylene tetrahydropteroylpentaglutamate
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
reaction of the choline degradation pathway
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
reaction of the choline degradation pathway
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
reaction of the choline degradation pathway
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
reaction of the choline degradation pathway
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
reaction of the choline degradation pathway
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
reaction of the choline degradation pathway
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
reaction of the choline degradation pathway
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
tetrahydropteroylpentaglutamate is used in vivo as an acceptor of the one-carbon group generated during the reaction
-
?
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Carcinoma, Hepatocellular
LncRNA RP11-422N16.3 Inhibits Cell Proliferation and EMT, and Induces Apoptosis in Hepatocellular Carcinoma Cells by Sponging miR-23b-3p.
Carcinoma, Hepatocellular
Potential diagnostic and prognostic marker dimethylglycine dehydrogenase (DMGDH) suppresses hepatocellular carcinoma metastasis in vitro and in vivo.
Carcinoma, Hepatocellular
Rat liver dimethylglycine dehydrogenase. Flavinylation of the enzyme in hepatocytes in primary culture and characterization of a cDNA clone.
dimethylglycine dehydrogenase deficiency
Cloning of dimethylglycine dehydrogenase and a new human inborn error of metabolism, dimethylglycine dehydrogenase deficiency.
dimethylglycine dehydrogenase deficiency
Defect in dimethylglycine dehydrogenase, a new inborn error of metabolism: NMR spectroscopy study.
dimethylglycine dehydrogenase deficiency
Molecular basis of dimethylglycine dehydrogenase deficiency associated with pathogenic variant H109R.
dimethylglycine dehydrogenase deficiency
Structure and biochemical properties of recombinant human dimethylglycine dehydrogenase and comparison to the disease-related H109R variant.
dimethylglycine dehydrogenase deficiency
[DMGDH gene-related dimethylglycine dehydrogenase deficiency in a case].
Leukemia
Expression of acidosis-dependent genes in human cancer nests.
Liver Neoplasms
LncRNA RP11-422N16.3 Inhibits Cell Proliferation and EMT, and Induces Apoptosis in Hepatocellular Carcinoma Cells by Sponging miR-23b-3p.
Metabolism, Inborn Errors
Choline-related-inherited metabolic diseases-A mini review.
Neoplasm Metastasis
Potential diagnostic and prognostic marker dimethylglycine dehydrogenase (DMGDH) suppresses hepatocellular carcinoma metastasis in vitro and in vivo.
Neoplasms
Expression of acidosis-dependent genes in human cancer nests.
Neoplasms
LncRNA RP11-422N16.3 Inhibits Cell Proliferation and EMT, and Induces Apoptosis in Hepatocellular Carcinoma Cells by Sponging miR-23b-3p.
Non-alcoholic Fatty Liver Disease
Nonalcoholic Steatohepatitis is associated with a state of betaine-insufficiency.
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0.039 - 32.2
N,N-dimethylglycine
0.3 - 4.7
oxidized 2,6-dichlorophenolindophenol
14.65
sarcosine
pH 7.5, 60°C
1.4
Ferrocene
wild-type, pH 7.8, 25°C
32.2
Ferrocene
mutant H109R, pH 7.8, 25°C
0.039
N,N-dimethylglycine
-
and second value 15.4 mM, wild-type, pH 7.5, 25°C
0.045
N,N-dimethylglycine
-
and second value 1.10 mM, wild-type, presence of tetrahydrofolate, pH 7.5, 25°C
0.05
N,N-dimethylglycine
-
pH 7.0, 30°C, recombinant holoenzyme, 2 Km-values
0.3
N,N-dimethylglycine
25°C, pH 7.8, artificial electron acceptor: 2,6-dichlorophenolindophenol, wild-type enzyme
0.3
N,N-dimethylglycine
wild type enzyme, with 2,6-dichlorophenolindophenol as cosubstrate, at 25°C and pH 7.8 in 50 mM HEPES/NaOH with 150 mM NaCl
1.1
N,N-dimethylglycine
-
and first value 0.045 mM, wild-type, presence of tetrahydrofolate, pH 7.5, 25°C
1.4
N,N-dimethylglycine
25°C, pH 7.8, artificial electron acceptor: ferrocene, wild-type enzyme
1.4
N,N-dimethylglycine
wild type enzyme, with ferrocene as cosubstrate, at 25°C and pH 7.8 in 50 mM HEPES/NaOH with 150 mM NaCl
2.5 - 5
N,N-dimethylglycine
-
mutant H109R, pH 7.5, 25°C
4.7
N,N-dimethylglycine
25°C, pH 7.8, artificial electron acceptor: 2,6-dichlorophenolindophenol, mutant enzyme H109R
4.7
N,N-dimethylglycine
mutant enzyme H109R, with 2,6-dichlorophenolindophenol as cosubstrate, at 25°C and pH 7.8 in 50 mM HEPES/NaOH with 150 mM NaCl
8.6
N,N-dimethylglycine
pH 7.5, 60°C
9.4
N,N-dimethylglycine
-
pH 7.0, 30°C, recombinant holoenzyme, 2 Km-values
15.4
N,N-dimethylglycine
-
and first value 0.039 mM, wild-type, pH 7.5, 25°C
32.2
N,N-dimethylglycine
25°C, pH 7.8, artificial electron acceptor: ferrocene, mutant enzyme H109R
32.2
N,N-dimethylglycine
mutant enzyme H109R, with ferrocene as cosubstrate, at 25°C and pH 7.8 in 50 mM HEPES/NaOH with 150 mM NaCl
0.3
oxidized 2,6-dichlorophenolindophenol
wild-type, pH 7.8, 25°C
4.7
oxidized 2,6-dichlorophenolindophenol
mutant H109R, pH 7.8, 25°C
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Smith, L.T.; Pocard, J.A.; Bernard, T.; LeRudulier, D.
Osmotic control of glycine betaine biosynthesis and degradation in Rhizobium meliloti
J. Bacteriol.
170
3142-3149
1988
Sinorhizobium meliloti
brenda
Porter, D.H.; Cook, R.J.; Wagner, C.
Enzymatic properties of dimethylglycine dehydrogenase and sarcosine dehydrogenase from rat liver
Arch. Biochem. Biophys.
243
396-407
1985
Rattus norvegicus
brenda
Cook, R.J.; Misono, K.S.; Wagner, C.
The amino acid sequences of the flavin-peptides of dimethylglycine dehydrogenase and sarcosine dehydrogenase from rat liver mitochondria
J. Biol. Chem.
260
12998-13002
1985
Rattus norvegicus
brenda
Steenkamp, D.J.; Husain, M.
The effect of tetrahydrofolate on the reduction of electron transfer flavoprotein by sarcosine and dimethylglycine dehydrogenases
Biochem. J.
203
707-715
1982
Sus scrofa
brenda
Wittwer, A.J.; Wagner, C.
Identification of the folate-binding proteins of rat liver mitochondria as dimethylglycine dehydrogenase and sarcosine dehydrogenase. Flavoprotein nature and enzymatic properties of the purified proteins
J. Biol. Chem.
256
4109-4115
1981
Rattus norvegicus
brenda
Wittwer, A.J.; Wagner, C.
Identification of the folate-binding proteins of rat liver mitochondria as dimethylglycine dehydrogenase and sarcosine dehydrogenase. Purification and folate-binding characteristics
J. Biol. Chem.
256
4102-4108
1981
Rattus norvegicus
brenda
Cook, R.J.; Misono, K.S.; Wagner, C.
Identification of the covalently bound flavin of dimethylglycine dehydrogenase and sarcosine dehydrogenase from rat liver mitochondria
J. Biol. Chem.
259
12475-12480
1980
Rattus norvegicus
brenda
Frisell, W.R.; Mackenzie, C.G.
Sarcosine dehydrogenase and dimethylglycine dehydrogenase (rat liver, monkey liver)
Methods Enzymol.
17A
976-981
1970
Macaca mulatta, Rattus norvegicus
-
brenda
Frisell, W.R.; Mackenzie, C.G.
Separation and purification of sarcosine dehydrogenase and dimethylglycine dehydrogenase
J. Biol. Chem.
237
94-98
1962
Rattus norvegicus
brenda
Wagner, C.; Briggs, W.T.; Cook, R.J.
Covalent binding of folic acid to dimethylglycine dehydrogenase
Arch. Biochem. Biophys.
233
457-461
1984
Rattus norvegicus
brenda
Wittwer, A.J.; Wagner, C.
Identification of folate binding protein of mitochondria as dimethylglycine dehydrogenase
Proc. Natl. Acad. Sci. USA
77
4484-4488
1980
Rattus norvegicus
brenda
Lang, H.; Polster, M.; Brandsch, R.
Rat liver dimethylglycine dehydrogenase. Flavinylation of the enzyme in hepatocytes in primary culture and characterization of a cDNA clone
Eur. J. Biochem.
198
793-799
1991
Rattus norvegicus (Q63342)
brenda
Lang, H.; Minaian, K.; Freudenberg, N.; Hoffmann, R.; Brandsch, R.
Tissue specificity of rat mitochondrial dimethylglycine dehydrogenase expression
Biochem. J.
299
393-398
1994
Rattus norvegicus
-
brenda
Otto, A.; Stoltz, M.; Sailer, H.; Brandsch, R.
Biogenesis of the covalently flavinylated mitochondrial enzyme dimethylglycine dehydrogenase
J. Biol. Chem.
271
9823-9829
1996
Rattus norvegicus
brenda
Brizio, C.; Otto, A.; Brandsch, R.; Passarella, S.; Barile, M.
A protein factor of rat liver mitochondrial matrix involved in flavinylation of dimethylglycine dehydrogenase
Eur. J. Biochem.
267
4346-4354
2000
Oryctolagus cuniculus, Rattus norvegicus
brenda
Brizio, C.; Barile, M.; Brandsch, R.
Flavinylation of the precursor of mitochondrial dimethylglycine dehydrogenase by intact and solubilised mitochondria
FEBS Lett.
522
141-146
2002
Rattus norvegicus
brenda
Brizio, C.; Brandsch, R.; Bufano, D.; Pochini, L.; Indiveri, C.; Barile, M.
Over-expression in Escherichia coli, functional characterization and refolding of rat dimethylglycine dehydrogenase
Protein Expr. Purif.
37
434-442
2004
Rattus norvegicus
brenda
Brizio, C.; Brandsch, R.; Douka, M.; Wait, R.; Barile, M.
The purified recombinant precursor of rat mitochondrial dimethylglycine dehydrogenase binds FAD via an autocatalytic reaction
Int. J. Biol. Macromol.
42
455-462
2008
Rattus norvegicus (Q63342)
brenda
Pyo, J.O.; Nah, J.; Kim, H.J.; Chang, J.W.; Song, Y.W.; Yang, D.K.; Jo, D.G.; Kim, H.R.; Chae, H.J.; Chae, S.W.; Hwang, S.Y.; Kim, S.J.; Kim, H.J.; Cho, C.; Oh, C.G.; Park, W.J.; Jung, Y.K.
Protection of cardiomyocytes from ischemic/hypoxic cell death via Drbp1 and pMe2GlyDH in cardio-specific ARC transgenic mice
J. Biol. Chem.
283
30707-30714
2008
Mus musculus (Q9DBT9), Mus musculus
brenda
McAndrew, R.P.; Vockley, J.; Kim, J.J.
Molecular basis of dimethylglycine dehydrogenase deficiency associated with pathogenic variant H109R
J. Inherit. Metab. Dis.
31
761-768
2008
Homo sapiens
brenda
Luka, Z.; Pakhomova, S.; Loukachevitch, L.V.; Newcomer, M.E.; Wagner, C.
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Rattus norvegicus, Rattus norvegicus (Q5RKL4), Rattus norvegicus (Q63342)
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Augustin, P.; Hromic, A.; Pavkov-Keller, T.; Gruber, K.; Macheroux, P.
Structure and biochemical properties of recombinant human dimethylglycine dehydrogenase and comparison to the disease-related H109R variant
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Homo sapiens (Q9UI17), Homo sapiens
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Liu, G.; Hou, G.; Li, L.; Li, Y.; Zhou, W.; Liu, L.
Potential diagnostic and prognostic marker dimethylglycine dehydrogenase (DMGDH) suppresses hepatocellular carcinoma metastasis in vitro and in vivo
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Homo sapiens, Homo sapiens (Q9UI17)
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Yang, T.; Shao, Y.H.; Guo, L.Z.; Meng, X.L.; Yu, H.; Lu, W.D.
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Chromohalobacter salexigens (Q1QYW1), Chromohalobacter salexigens DSM 3043 (Q1QYW1), Chromohalobacter salexigens DSM 3043
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Sun, L.; Sun, J.; Xu, Q.; Li, X.; Zhang, L.; Yang, H.
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Apostichopus japonicus
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