Information on EC 1.6.5.7 - 2-hydroxy-1,4-benzoquinone reductase

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The expected taxonomic range for this enzyme is: Burkholderia

EC NUMBER
COMMENTARY hide
1.6.5.7
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RECOMMENDED NAME
GeneOntology No.
2-hydroxy-1,4-benzoquinone reductase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-hydroxy-1,4-benzoquinone + NADH + H+ = 1,2,4-trihydroxybenzene + NAD+
show the reaction diagram
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidation
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redox reaction
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reduction
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
2,4,5-trichlorophenoxyacetate degradation
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4-nitrophenol degradation II
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Chlorocyclohexane and chlorobenzene degradation
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Aminobenzoate degradation
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Metabolic pathways
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Microbial metabolism in diverse environments
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SYSTEMATIC NAME
IUBMB Comments
2-hydroxy-1,4-benzoquinone:NADH oxidoreductase
A flavoprotein (FMN) that differs in substrate specificity from other quinone reductases. The enzyme in Burkholderia cepacia is inducible by 2,4,5-trichlorophenoxyacetate.
CAS REGISTRY NUMBER
COMMENTARY hide
214466-94-1
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
strain AC1100
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Manually annotated by BRENDA team
strain AC1100
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Manually annotated by BRENDA team
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Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
metabolism
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-hydroxy-[1,4]-benzoquinone + NADH
1,2,4-trihydroxybenzene + NAD+
show the reaction diagram
5-chloro-2-hydroxy-[1,4]-benzoquinone + NADH
5-chloro-1,2,4-trihydroxybenzene + NAD+
show the reaction diagram
additional information
?
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COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
3
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with succinate as carbon source
68
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after induction with 2,4,5-trichlorophenoxyacetic acid
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
50000
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gel filtration, Sephacryl S100
SUBUNITS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
3-step purification, 27fold enrichment
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