Information on EC 2.1.1.123 - [cytochrome-c]-methionine S-methyltransferase

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The expected taxonomic range for this enzyme is: Euglena gracilis

EC NUMBER
COMMENTARY hide
2.1.1.123
-
RECOMMENDED NAME
GeneOntology No.
[cytochrome-c]-methionine S-methyltransferase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + [cytochrome c]-methionine = S-adenosyl-L-homocysteine + [cytochrome c]-S-methyl-methionine
show the reaction diagram
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
methyl group transfer
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
S-adenosyl-L-methionine:[cytochrome c]-methionine S-methyltransferase
The enzyme from Euglena gracilis methylates Met-65 of horse heart cytochrome c.
CAS REGISTRY NUMBER
COMMENTARY hide
93585-98-9
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
-
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
S-Adenosyl-L-methionine + [cytochrome c]-methionine
S-Adenosyl-L-homocysteine + [cytochrome c]-S-methyl-methionine
show the reaction diagram
INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
S-Adenosyl-D-homocysteine
-
-
S-adenosyl-L-homocysteine
-
-
sinefungin
-
-
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0166
S-adenosyl-L-methionine
-
-
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.0000686
-
-
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
28000
-
gel filtration
STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
-70°C, 50% loss of activity after 1 week
-
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE