Disease on EC 2.1.1.43 - histone-lysine N-methyltransferase

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Breast Neoplasms

Interaction of BARD1 and HP1 is required for BRCA1 retention at sites of DNA damage.

Chagas Disease

Antiproliferative effects of delta 24(25) sterol methyl transferase inhibitors on Trypanosoma (Schizotrypanum) cruzi: in vitro and in vivo studies.

Glioma

Role of Histone Lysine Methyltransferases SUV39H1 and SETDB1 in Gliomagenesis: Modulation of Cell Proliferation, Migration, and Colony Formation.

Lung Neoplasms

Deregulation of histone lysine methyltransferases contributes to oncogenic transformation of human bronchoepithelial cells.

Malaria

Designing synthetic drugs against Plasmodium falciparum: a computational study of histone-lysine N-methyltransferase (PfHKMT).

Neoplasm Metastasis

Genomic landscape of metastatic breast cancer identifies preferentially dysregulated pathways and targets.

Neoplasms

Chaetocin induced chromatin condensation: effect on DNA repair signaling and survival.