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Disease on EC 2.2.1.1 - transketolase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acidosis
[Biochemical markers of strophanthin arrhythmia]
Acidosis, Lactic
Clinical and biochemical aspects of thiamine treatment for metabolic acidosis during total parenteral nutrition.
Outbreak of life-threatening thiamine deficiency in infants in Israel caused by a defective soy-based formula.
Acquired Immunodeficiency Syndrome
Conserved residues are functionally distinct within transketolases of different species.
Thiamine deficiency and Wernicke's encephalopathy in AIDS.
Adenocarcinoma
Inhibition of the oxidative and nonoxidative pentose phosphate pathways by somatostatin: a possible mechanism of antitumor action.
Nonoxidative pentose phosphate pathways and their direct role in ribose synthesis in tumors: is cancer a disease of cellular glucose metabolism?
TKTL1 as a Prognostic Marker in Pancreatic Ductal Adenocarcinoma and Its Correlation with FDG-PET-CT.
Transketolase-like 1 expression correlates with subtypes of ovarian cancer and the presence of distant metastases.
Transketolase-like protein 1 expression predicts poor prognosis in colorectal cancer.
Adenoma
A first immunohistochemistry study of transketolase and transketolase-like 1 expression in canine hyperplastic and neoplastic mammary lesions.
[Glucose-6-phosphate dehydrogenase and transketolase activity in the blood of neurological oncologic patients preoperatively and in the dynamics of the postoperative period]
AIDS-Related Complex
Thiamine deficiency and Wernicke's encephalopathy in AIDS.
Alcoholic Neuropathy
Erythrocyte transketolase activity in patients with diabetic and alcoholic neuropathies.
Alzheimer Disease
Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy.
Cerebrospinal fluid levels of thiamine in patients with Alzheimer's disease.
Cysteine proteinases are responsible for characteristic transketolase alterations in Alzheimer fibroblasts.
Effects of magnesium, high energy phosphates, piracetam and thiamin on erythrocyte transketolase.
In situ localization of transketolase activity in epithelial cells of different rat tissues and subcellularly in liver parenchymal cells.
Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer.
Occurrence of transketolase abnormalities in extracts of foreskin fibroblasts from patients with Alzheimer's disease.
Properties and functions of the thiamin diphosphate dependent enzyme transketolase.
Studies of transketolase abnormality in Alzheimer's disease.
Thiamine-dependent enzyme changes in temporal cortex of patients with Alzheimer's disease.
Amblyopia
Blood transketolase levels in tobacco-alcohol amblyopia.
Anaplasia
Anaplastic nephroblastomas express transketolase-like enzyme 1.
Anemia
Anaemia and erythrocyte transketolase activity.
Eighteen-month follow-up of infants fed evaporated milk formula.
Erythrocyte transketolase activity and anaemia.
The transketolase assay of thiamine in some diseases.
Transketolase in sickel cell anemia.
Aneurysm
[Enzyme activity in post-infarct aneurysm and in the myocardial zone outside the infarct in experimental infarct in rats]
Arrhythmias, Cardiac
[Biochemical markers of strophanthin arrhythmia]
Arthritis, Rheumatoid
Sialic acid, transketolase and Na+, K+, ATPase in patients with rheumatoid arthritis.
Aspergillosis
Statistical analysis of pentose phosphate pathway genes from eubacteria and eukarya reveals translational selection as a major force in shaping codon usage pattern.
Astrocytoma
Expression of transketolase-like 1 and activation of Akt in grade IV glioblastomas compared with grades II and III astrocytic gliomas.
Ataxia
Activities of thiamine-dependent enzymes in two experimental models of thiamine-deficiency encephalopathy: 1. The pyruvate dehydrogenase complex.
Alcoholic cerebellar degeneration is not a dose-dependent phenomenon.
Thiamine deficiency and the etiology of tropical ataxic neuropathy.
Avitaminosis
Water soluble vitamins in chronic hemodialysis patients and need for supplementation.
[Blood transketolase activity and the TDP effect as indices of thiamine body allowance]
[Content of free and bound thiamine diphosphate in the liver hyaloplasm of vitamine B1 deficient rats]
[Enzyme activity of thiamine diphosphate biosynthesis and degradation in the mouse liver in the dynamics of B1 avitaminosis development]
[Experimental evaluation of the effectiveness of vitamin-enriched chopped meat products]
[Metabolic effects related to transketolase inhibition]
[The transketolase activity in erythrocytes as a criterion for thiamine balance in the body]
[Transketolase in the nerve tissue in avitaminosis B1 in pigeons.]
Beriberi
Beriberi heart disease in Durban. A retrospective study.
Blood transketolase activity in beriberi heart disease. A useful diagnostic index.
Blood vitamin B1, transketolase and thiamine pyrophosphate (TPP) effect in beriberi patients, with studies employing discriminant analysis.
Comparison of Thiamin Diphosphate High-Performance Liquid Chromatography and Erythrocyte Transketolase Assays for Evaluating Thiamin Status in Malaria Patients without Beriberi.
Erythrocyte transketolase activity, markers of cardiac dysfunction and the diagnosis of infantile beriberi.
Shoshin beriberi: an unusual complication of prolonged parenteral nutrition.
[Effect of thiamine on the transketolase activity of the pigeon with beriberi.]
Brain Diseases
Amprolium poisoning of preruminant lambs: an investigation of the encephalopathy and the haemorrhagic and diarrhoeic syndromes.
Breast Neoplasms
Glucose-6-phosphate dehydrogenase and transketolase modulate breast cancer cell metabolic reprogramming and correlate with poor patient outcome.
Glycolytic phenotype in breast cancer: activation of Akt, up-regulation of GLUT1, TKTL1 and down-regulation of M2PK.
Poor outcome in primary non-small cell lung cancers is predicted by transketolase TKTL1 expression.
The thiamin status of early cancer patients with particular reference to those with breast and bronchial carcinomas.
Transketolase protein TKTL1 overexpression: A potential biomarker and therapeutic target in breast cancer.
Transketolase regulates the metabolic switch to control breast cancer cell metastasis via the alpha-ketoglutarate signaling pathway.
Carcinogenesis
A review on research progress of transketolase.
Association of cancer metabolism-related proteins with oral carcinogenesis - indications for chemoprevention and metabolic sensitizing of oral squamous cell carcinoma?
Differential proteomic analysis of hepatocellular carcinoma.
Expression of transketolase-like 1 (TKTL1) and p-Akt correlates with the progression of cervical neoplasia.
Prognostic values of transketolase family genes in ovarian cancer.
Silencing of TKTL1 by siRNA inhibits proliferation of human gastric cancer cells in vitro and in vivo.
TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization.
TKTL1 promotes cell proliferation and metastasis in esophageal squamous cell carcinoma.
Transketolase Deficiency Protects the Liver from DNA Damage by Increasing Levels of Ribose 5-Phosphate and Nucleotides.
Transketolase like 1 (TKTL1) expression alterations in prostate cancer tumorigenesis.
Carcinoma
A first immunohistochemistry study of transketolase and transketolase-like 1 expression in canine hyperplastic and neoplastic mammary lesions.
EDIM-TKTL1/Apo10 Blood Test: An Innate Immune System Based Liquid Biopsy for the Early Detection, Characterization and Targeted Treatment of Cancer.
Exchange reactions catalyzed by group-transferring enzymes oppose the quantitation and the unravelling of the identify of the pentose pathway.
Expression of transketolase-like 1 (TKTL1) and p-Akt correlates with the progression of cervical neoplasia.
Identification of potential canine mammary tumour cell biomarkers using proteomic approach: Differences in protein profiles among tumour and normal mammary epithelial cells by two-dimensional electrophoresis-based mass spectrometry.
Overexpression of transketolase TKTL1 is associated with shorter survival in laryngeal squamous cell carcinomas.
Sugiol inhibits STAT3 activity via regulation of transketolase and ROS-mediated ERK activation in DU145 prostate carcinoma cells.
Thiamine metabolism in the liver of mice with Ehrlich ascites carcinoma.
TKTL1 and p63 are biomarkers for the poor prognosis of gastric cancer patients.
TKTL1 expression and its downregulation is implicated in cell proliferation inhibition and cell cycle arrest in esophageal squamous cell carcinoma.
TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization.
TKTL1 promotes cell proliferation and metastasis in esophageal squamous cell carcinoma.
Transketolase-like 1 expression correlates with subtypes of ovarian cancer and the presence of distant metastases.
Transketolase-like protein 1 (TKTL1) is required for rapid cell growth and full viability of human tumor cells.
Transketolase-like protein 1 confers resistance to serum withdrawal in vitro.
[Expression and clinical significance of MTDH, HIF-1? and TKTL1 in laryngeal carcinoma].
[Metabolism of vitamins B1 and PP and their use in oncological practice]
[Transketolase activity and the TDP effect in tissues of animals with experimental tumors]
Carcinoma, Hepatocellular
A Correlative Study Between IVIM-DWI Parameters and the Expression Levels of Ang-2 and TKT in Hepatocellular Carcinoma.
Behavior of transaldolase (EC 2.2.1.2) and transketolase (EC 2.2.1.1) Activities in normal, neoplastic, differentiating, and regenerating liver.
Effects of vitamins B1, B2, B6 and C on erythrocyte enzymes in South African Bantu.
Elevated activity of the oxidative and non-oxidative pentose phosphate pathway in (pre)neoplastic lesions in rat liver.
Exchange reactions catalyzed by group-transferring enzymes oppose the quantitation and the unravelling of the identify of the pentose pathway.
Gene silencing of TKTL1 by RNAi inhibits cell proliferation in human hepatoma cells.
The nuclear translocation of transketolase inhibits the farnesoid receptor expression by promoting the binding of HDAC3 to FXR promoter in hepatocellular carcinoma cell lines.
Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner.
[Activities of dehydrogenases of the pentose phosphate pathway and transketolase in transplanted mouse hepatomas with different growth rates and in organs of tumor carriers]
Carcinoma, Intraductal, Noninfiltrating
Glycolytic phenotype in breast cancer: activation of Akt, up-regulation of GLUT1, TKTL1 and down-regulation of M2PK.
Carcinoma, Non-Small-Cell Lung
Cryptotanshinone strengthens the effect of gefitinib against non-small cell lung cancer through inhibiting transketolase.
Poor outcome in primary non-small cell lung cancers is predicted by transketolase TKTL1 expression.
TKTL1 is overexpressed in a large portion of non-small cell lung cancer specimens.
Carcinoma, Squamous Cell
Expression of transketolase-like 1 (TKTL1) and p-Akt correlates with the progression of cervical neoplasia.
Overexpression of transketolase TKTL1 is associated with shorter survival in laryngeal squamous cell carcinomas.
TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization.
Transketolase-like protein 1 confers resistance to serum withdrawal in vitro.
Carcinosarcoma
[Level of thiamine diphosphate in the liver of tumor-bearing animals kept on a diet including an excessive amount of vitamin B 1]
Cataract
Changes in glutathione, glutathione-linked enzymes and hexose monophosphate shunt enzymes in senile cataract.
Cholecystitis
[Activity of serum transketolase in patients with cholecystitis]
Colitis
Lack of transketolase-like (TKTL) 1 aggravates murine experimental colitis.
Colonic Neoplasms
Modulation of pentose phosphate pathway during cell cycle progression in human colon adenocarcinoma cell line HT29.
The TKTL1 gene influences total transketolase activity and cell proliferation in human colon cancer LoVo cells.
Colorectal Neoplasms
Biomarkers Apo10 and TKTL1: Epitope-detection in monocytes (EDIM) as a new diagnostic approach for cholangiocellular, pancreatic and colorectal carcinoma.
High TKTL1 expression as a sign of poor prognosis in colorectal cancer with synchronous rather than metachronous liver metastases.
Hypoxia induces the expression of transketolase-like 1 in human colorectal cancer.
TKTL1 promotes cell proliferation and metastasis in esophageal squamous cell carcinoma.
Transketolase protein TKTL1 overexpression: A potential biomarker and therapeutic target in breast cancer.
Transketolase-like 1 expression is modulated during colorectal cancer progression and metastasis formation.
Transketolase-like protein 1 expression predicts poor prognosis in colorectal cancer.
Confusion
Exchange reactions catalyzed by group-transferring enzymes oppose the quantitation and the unravelling of the identify of the pentose pathway.
Crohn Disease
Erythrocyte transketolase deficiency in patients suffering from Crohn's disease.
Cysts
Univariate and classification analysis reveals potential diagnostic biomarkers for early stage ovarian cancer Type 1 and Type 2.
Deficiency Diseases
Transketolase abnormality in cultured fibroblasts from familial chronic alcoholic men and their male offspring.
Dehydration
Proteomic analyses unraveling water stress response in two Eucalyptus species originating from contrasting environments for aridity.
Sweet siblings with different faces: the mechanisms of FBP and F6P aldolase, transaldolase, transketolase and phosphoketolase revisited in light of recent structural data.
Dementia
The activation of red blood cell transketolase in groups of patients especially at risk from thiamin deficiency.
Dermatitis, Contact
[Enzymatic activity of the pentosephosphate pathway of carbohydrate conversion in the experimental therapy of dermatitis in rats]
Diabetes Complications
Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives.
Thiamine status in patients undergoing lower extremity amputation due to diabetic foot lesion.
Diabetes Mellitus
d-Ribose as a Contributor to Glycated Haemoglobin.
Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer.
The transketolase assay of thiamine in some diseases.
[Activity of blood transketolase in patients with diabetes mellitus]
[Thiamine content and transketolase activity in organs of albino rats with diabetes mellitus]
Diabetes Mellitus, Experimental
Effect of alloxan diabetes and cortisol on glucose-6-phosphate dehydrogenase and transketolase in rabbit liver mitochondria.
Diabetes Mellitus, Type 2
d-Ribose as a Contributor to Glycated Haemoglobin.
Might genetics play a role in understanding and treating diabetic polyneuropathy?
Diabetic Nephropathies
Genetic variability in enzymes of metabolic pathways conferring protection against non-enzymatic glycation versus diabetes-related morbidity and mortality.
Role of thiamine status and genetic variability in transketolase and other pentose phosphate cycle enzymes in the progression of diabetic nephropathy.
Diabetic Neuropathies
Association of transketolase polymorphisms with measures of polyneuropathy in patients with recently diagnosed diabetes.
The correlation between the activation coefficient of erythrocyte transketolase activity and diabetic neuropathy.
Diabetic Retinopathy
Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy.
Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer.
Vitamin B1 blocks damage caused by hyperglycemia.
Drug Eruptions
[Transketolase activity as a parameter for the vitamin B1 provision in some dermatoses (herpes zoster, psoriasis, drug eruptions, excema, and urticaria) (author's transl)]
Echinococcosis
[Cloning, expression and immunity analysis of transketolase of Echinococcus granulosus].
Endometrial Neoplasms
Expression of transketolase-like 1 protein (TKTL1) in human endometrial cancer.
Esophageal Neoplasms
Transketolase Serves a Poor Prognosticator in Esophageal Cancer by Promoting Cell Invasion via Epithelial-Mesenchymal Transition.
Esophageal Squamous Cell Carcinoma
TKTL1 expression and its downregulation is implicated in cell proliferation inhibition and cell cycle arrest in esophageal squamous cell carcinoma.
TKTL1 promotes cell proliferation and metastasis in esophageal squamous cell carcinoma.
Fibromyalgia
Effects of magnesium, high energy phosphates, piracetam and thiamin on erythrocyte transketolase.
Transketolase stimulation in fibromyalgia.
Folic Acid Deficiency
Biochemical evidence of thiamin deficiency in young Ghanian children.
Gastroesophageal Reflux
Multiple causes of asphyxia in infants at high risk for sudden infant death.
Genetic Diseases, Inborn
Nucleotide and predicted amino acid sequence of a cDNA clone encoding part of human transketolase.
Glioblastoma
Expression of transketolase-like 1 and activation of Akt in grade IV glioblastomas compared with grades II and III astrocytic gliomas.
Glioma
Gene Suppression of Transketolase-Like Protein 1 (TKTL1) Sensitizes Glioma Cells to Hypoxia and Ionizing Radiation.
glucose-6-phosphate dehydrogenase (nadp+) deficiency
Metabolic reprogramming and redox adaptation in sorafenib-resistant leukemia cells: detected by untargeted metabolomics and stable isotope tracing analysis.
Glucosephosphate Dehydrogenase Deficiency
Metabolic reprogramming and redox adaptation in sorafenib-resistant leukemia cells: detected by untargeted metabolomics and stable isotope tracing analysis.
Glycogen Storage Disease Type I
[Transketolase and transaldolase in the liver in Gierke's disease.]
Granulosa Cell Tumor
Glucose metabolism and angiogenesis in granulosa cell tumors of the ovary: activation of Akt, expression of M2PK, TKTL1 and VEGF.
Head and Neck Neoplasms
c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation.
Heart Diseases
Blood transketolase activity in beriberi heart disease. A useful diagnostic index.
[Transketolase activity in rabbit myocardium and erythrocytes in health and in allergic heart diseases]
Hepatic Insufficiency
The influence of hepatic insufficiency due to alcoholic cirrhosis on the erythrocyte transketolase activity (ETKA).
Herpes Zoster
[Transketolase activity as a parameter for the vitamin B1 provision in some dermatoses (herpes zoster, psoriasis, drug eruptions, excema, and urticaria) (author's transl)]
Hyperglycemia
Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease.
Melatonin attenuates metabolic disorders due to streptozotocin-induced diabetes in rats.
Hypokinesia
[Features of thiamine metabolism with vitamin B1 deficiency in hypokinesis]
[Several indicators of protein and nucleic acid metabolism in lymphoid organs of rats exposed to hypokinesia and vitamin B1 deficiency]
Infections
Catharanthus roseus genes regulated differentially by mollicute infections.
Development of Clade-Specific and Broadly Reactive Live Attenuated Influenza Virus Vaccines against Rapidly Evolving H5 Subtype Viruses.
Subacute sensory ataxia and optic neuropathy with thiamine deficiency.
Transketolase of Staphylococcus aureus is involved in the control of master regulators of stress response during infection.
[Glycolysis and pentose-phosphate pathway ratio in staphylococcus from the female genitalia in norm and dysbiosis]
Infertility, Male
The pathogenesis of transaldolase deficiency.
Inflammatory Bowel Diseases
TKT maintains intestinal ATP production and inhibits apoptosis-induced colitis.
Influenza in Birds
Antigenic characterization of recent H5N1 highly pathogenic avian influenza viruses circulating in Egyptian poultry.
Development of Clade-Specific and Broadly Reactive Live Attenuated Influenza Virus Vaccines against Rapidly Evolving H5 Subtype Viruses.
Different counteracting host immune responses to clade 2.2.1.1 and 2.2.1.2 Egyptian H5N1 highly pathogenic avian influenza viruses in naïve and vaccinated chickens.
Pathogenicity of the Egyptian A/H5N1 avian influenza viruses in chickens.
Re-Emergence of a Novel H5N1 Avian Influenza Virus Variant Subclade 2.2.1.1 in Egypt During 2014.
Variation in protection of four divergent avian influenza virus vaccine seed strains against eight clade 2.2.1 and 2.2.1.1. Egyptian H5N1 high pathogenicity variants in poultry.
Influenza, Human
Phylogeography of influenza A H5N1 clade 2.2.1.1 in Egypt.
Insulinoma
Detection Of Transketolase In Bone Marrow-Derived Insulin Producing Cells: Benfotiamine Enhances Insulin Synthesis And Glucose Metabolism.
Kidney Failure, Chronic
Comparison of the thiamine level in blood and erythrocyte transketolase activity in hemodialyzed and nondialyzed patients during recombinant human erythropoietin therapy.
High thiamine diphosphate concentrations in erythrocytes can be achieved in dialysis patients by oral administration of benfontiamine.
The uremic toxin oxythiamine causes functional thiamine deficiency in end-stage renal disease by inhibiting transketolase activity.
[Catalytic activity of transketolase in erythrocytes in chronic kidney failure]
[The effect of cocarboxylase treatment on erythrocyte transketolase and blood thiamine in patients with end stage renal disease undergoing maintenance hemodialysis]
Korsakoff Syndrome
A biochemical abnormality of transketolase in patients with Wernicke-Korsakoff syndrome.
A transketolase assembly defect in a Wernicke-Korsakoff syndrome patient.
An enzymatic and immunochemical analysis of transketolase in fibroblasts from Wernicke-Korsakoff syndrome.
An erythrocyte transketolase isoenzyme pattern associated with the Wernicke-Korsakoff syndrome.
Cloning of human transketolase cDNAs and comparison of the nucleotide sequence of the coding region in Wernicke-Korsakoff and non-Wernicke-Korsakoff individuals.
Effect of chronic alcohol administration on transketolase in the brain and the liver of rats.
Erythrocyte transketolase activity in the Wernicke-Korsakoff syndrome.
Molecular genetics of transketolase in the pathogenesis of the Wernicke-Korsakoff syndrome.
Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer.
Nucleotide and predicted amino acid sequence of a cDNA clone encoding part of human transketolase.
Optimum nutrition: thiamin, biotin and pantothenate.
Transketolase abnormality in cultured fibroblasts from familial chronic alcoholic men and their male offspring.
Transketolase abnormality in tolazamide-induced Wernicke's encephalopathy.
Leigh Disease
Erythrocyte transketolase activity in suspected cases of Leigh's disease, or subacute necrotising encephalomyelopathy.
Leiomyoma
Glucose metabolism of malignant cells is not regulated by transketolase-like (TKTL)-1.
Liver Cirrhosis, Alcoholic
The influence of hepatic insufficiency due to alcoholic cirrhosis on the erythrocyte transketolase activity (ETKA).
Liver Diseases
Erythrocyte transketolase activity in alcoholic liver disease.
Red blood cell transketolase activity and the effect of thiamine supplementation in patients with chronic liver disease.
Transaldolase haploinsufficiency in subjects with acetaminophen-induced liver failure.
Liver Diseases, Alcoholic
Erythrocyte transketolase activity in alcoholic liver disease.
Liver Failure
Vitamin B 1, B 2 and B 6 deficiency in neurological disorders.
Lung Neoplasms
Cryptotanshinone strengthens the effect of gefitinib against non-small cell lung cancer through inhibiting transketolase.
Effect of siRNA-mediated gene silencing of transketolase on A549 lung cancer cells.
Poor outcome in primary non-small cell lung cancers is predicted by transketolase TKTL1 expression.
TKTL-1 expression in lung cancer.
TKTL1 is overexpressed in a large portion of non-small cell lung cancer specimens.
Lymphatic Metastasis
TKTL1 and p63 are biomarkers for the poor prognosis of gastric cancer patients.
TKTL1 expression and its downregulation is implicated in cell proliferation inhibition and cell cycle arrest in esophageal squamous cell carcinoma.
[Effects of transketolase-like gene TKTL1 on occurrence and metastasis of human nasopharyngeal carcinoma]
Magnesium Deficiency
Effect of magnesium deficiency on blood and liver transketolase activity and on the recovery of enzyme activity in thiamine-deficient rats receiving thiamine.
Malaria
Comparison of Thiamin Diphosphate High-Performance Liquid Chromatography and Erythrocyte Transketolase Assays for Evaluating Thiamin Status in Malaria Patients without Beriberi.
Molecular-docking study of malaria drug target enzyme transketolase in Plasmodium falciparum 3D7 portends the novel approach to its treatment.
Thiamin deficiency and uncomplicated falciparum malaria in Laos.
Thiamine deficiency and malaria in adults from southeast Asia.
Malnutrition
Red cell transketolase as an indicator of nutritional deficiency.
The age dependence of the activity and activation of human red blood cell transketolase.
The transketolase assay of thiamine in some diseases.
Vagal neuropathy in chronic alcoholics: relation to ethanol consumption.
Vitamin B 1, B 2 and B 6 deficiency in neurological disorders.
Melanoma
Exchange reactions catalyzed by group-transferring enzymes oppose the quantitation and the unravelling of the identify of the pentose pathway.
Transketolase-like 1 ectopic expression is associated with DNA hypomethylation and induces the Warburg effect in melanoma cells.
Metabolism, Inborn Errors
Mutations in TKT Are the Cause of a Syndrome Including Short Stature, Developmental Delay, and Congenital Heart Defects.
Untargeted metabolomics as an unbiased approach to the diagnosis of inborn errors of metabolism of the non-oxidative branch of the pentose phosphate pathway.
Mitral Valve Stenosis
[Activity of enzymes of pentosephosphate pathway in the erythrocytes, myocardium and intercostal muscle of patients with mitral valve stenosis]
Multiple Sclerosis
Transketolase and 2',3'-cyclic-nucleotide 3'-phosphodiesterase type I isoforms are specifically recognized by IgG autoantibodies in multiple sclerosis patients.
Muscular Atrophy, Spinal
Muscle transketolase in normal foetuses and Duchenne dystrophy.
Muscular Dystrophies
[On the glucose-6-phosphate dehydrogenase and transketolase activities in the serum of subjects with progressive muscular dystrophy.]
Muscular Dystrophy, Duchenne
Muscle transketolase in normal foetuses and Duchenne dystrophy.
Myocardial Infarction
[THE BLOOD SERUM TRANSKETOLASE REACTION IN MYOCARDIAL INFARCT.]
[Thiamine metabolism and transketolase activity of tissues in experimental myocardial infarct]
Myocarditis
[Use of glucose-6-phosphate dehydrogenase and transketolase for characterization of pathologic processes in the myocardium in rheumatism]
Nasopharyngeal Carcinoma
Knockdown of TKTL1 additively complements cisplatin-induced cytotoxicity in nasopharyngeal carcinoma cells by regulating the levels of NADPH and ribose-5-phosphate.
Overexpression of transketolase protein TKTL1 is associated with occurrence and progression in nasopharyngeal carcinoma: A potential therapeutic target in nasopharyngeal carcinoma.
Retraction. Overexpression of transketolase protein TKTL1 is associated with occurrence and progression in nasopharyngeal carcinoma.
[Effects of transketolase-like gene TKTL1 on occurrence and metastasis of human nasopharyngeal carcinoma]
Nasopharyngitis
Overexpression of transketolase protein TKTL1 is associated with occurrence and progression in nasopharyngeal carcinoma: A potential therapeutic target in nasopharyngeal carcinoma.
[Effects of transketolase-like gene TKTL1 on occurrence and metastasis of human nasopharyngeal carcinoma]
Neoplasm Metastasis
Biomarkers Apo10 and TKTL1: Epitope-detection in monocytes (EDIM) as a new diagnostic approach for cholangiocellular, pancreatic and colorectal carcinoma.
Expression of the mutated transketolase TKTL1, a molecular marker in gastric cancer.
Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted.
High TKTL1 expression as a sign of poor prognosis in colorectal cancer with synchronous rather than metachronous liver metastases.
Increased expression of transketolase-like-1 in papillary thyroid carcinomas smaller than 1.5 cm in diameter is associated with lymph-node metastases.
Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer.
Prognostic values of transketolase family genes in ovarian cancer.
Proteomics analysis of differentially expressed metastasis-associated proteins in adenoid cystic carcinoma cell lines of human salivary gland.
TKTL1 and p63 are biomarkers for the poor prognosis of gastric cancer patients.
TKTL1 expression and its downregulation is implicated in cell proliferation inhibition and cell cycle arrest in esophageal squamous cell carcinoma.
TKTL1 promotes cell proliferation and metastasis in esophageal squamous cell carcinoma.
Transketolase regulates the metabolic switch to control breast cancer cell metastasis via the alpha-ketoglutarate signaling pathway.
Transketolase-like 1 expression correlates with subtypes of ovarian cancer and the presence of distant metastases.
Transketolase-like 1 expression is modulated during colorectal cancer progression and metastasis formation.
Transketolase-like protein 1 expression in recurrent oral squamous cell carcinoma after curative resection: a case report.
[Effects of transketolase-like gene TKTL1 on occurrence and metastasis of human nasopharyngeal carcinoma]
[Expression and clinical significance of MTDH, HIF-1? and TKTL1 in laryngeal carcinoma].
Neoplasms
A ?38 deletion variant of human transketolase as a model of transketolase-like protein 1 exhibits no enzymatic activity.
A first immunohistochemistry study of transketolase and transketolase-like 1 expression in canine hyperplastic and neoplastic mammary lesions.
A key role for transketolase-like 1 in tumor metabolic reprogramming.
A review on research progress of transketolase.
Activities of enzymes of the hexose monophosphate pathway in nervous system tumors induced by ethylnitrosourea.
Amplification of the transketolase gene in desensitization-resistant mutant Y1 mouse adrenocortical tumor cells.
Anaplastic nephroblastomas express transketolase-like enzyme 1.
Antitumor activity of hydroxythiamine and methotrexate immobilized on monocarboxycellulose.
Behavior of transaldolase (EC 2.2.1.2) and transketolase (EC 2.2.1.1) Activities in normal, neoplastic, differentiating, and regenerating liver.
Biomarkers Apo10 and TKTL1: Epitope-detection in monocytes (EDIM) as a new diagnostic approach for cholangiocellular, pancreatic and colorectal carcinoma.
Computer modeling of transketolase-like protein, TKTL1, a marker of certain tumor tissues.
Differential protein expression in honeybee (Apis mellifera L.) larvae: underlying caste differentiation.
Dual effects for lovastatin in anaplastic thyroid cancer: the pivotal effect of transketolase (TKT) on lovastatin and tumor proliferation.
EDIM-TKTL1 blood test: a noninvasive method to detect upregulated glucose metabolism in patients with malignancies.
EDIM-TKTL1/Apo10 Blood Test: An Innate Immune System Based Liquid Biopsy for the Early Detection, Characterization and Targeted Treatment of Cancer.
Effect of radical prostatectomy on levels of cancer related epitopes in circulating macrophages of patients with clinically localized prostate cancer.
Enhanced TKTL1 Expression in Malignant Tumors of the Ocular Adnexa Predicts Clinical Outcome.
Evaluation of a biomarker based blood test for monitoring surgical resection of oral squamous cell carcinomas.
Evaluation of TKTL1 as a biomarker in serum of prostate cancer patients.
Evidence against a Major Role for TKTL-1 in Hypoxic and Normoxic Cancer Cells.
Expression of the mutated transketolase TKTL1, a molecular marker in gastric cancer.
Expression of Transketolase like gene 1 (TKTL1) predicts disease-free survival in patients with locally advanced rectal cancer receiving neoadjuvant chemoradiotherapy.
Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted.
Expression of transketolase-like 1 (TKTL1) and p-Akt correlates with the progression of cervical neoplasia.
Expression of transketolase-like 1 and activation of Akt in grade IV glioblastomas compared with grades II and III astrocytic gliomas.
Expression of transketolase-like 1 protein (TKTL1) in human endometrial cancer.
Expression of transketolase-like gene 1 (TKTL1) depends on disease phase in patients with chronic myeloid leukaemia (CML).
Gene silencing of TKTL1 by RNAi inhibits cell proliferation in human hepatoma cells.
Gene Suppression of Transketolase-Like Protein 1 (TKTL1) Sensitizes Glioma Cells to Hypoxia and Ionizing Radiation.
Glucose metabolism and angiogenesis in granulosa cell tumors of the ovary: activation of Akt, expression of M2PK, TKTL1 and VEGF.
Glucose metabolism of malignant cells is not regulated by transketolase-like (TKTL)-1.
Glucose transporter GLUT1 expression is an stage-independent predictor of clinical outcome in adrenocortical carcinoma.
Glycolytic phenotype in breast cancer: activation of Akt, up-regulation of GLUT1, TKTL1 and down-regulation of M2PK.
Growth of human gastric cancer cells in nude mice is delayed by a ketogenic diet supplemented with omega-3 fatty acids and medium-chain triglycerides.
High TKTL1 expression as a sign of poor prognosis in colorectal cancer with synchronous rather than metachronous liver metastases.
Homology modeling of human transketolase: description of critical sites useful for drug design and study of the cofactor binding mode.
Hypoxia induces the expression of transketolase-like 1 in human colorectal cancer.
Identification of novel small-molecule inhibitors for human transketolase by high-throughput screening with fluorescent intensity (FLINT) assay.
Identification of potential canine mammary tumour cell biomarkers using proteomic approach: Differences in protein profiles among tumour and normal mammary epithelial cells by two-dimensional electrophoresis-based mass spectrometry.
Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1alpha-induced metabolic reprograming.
In situ localization of transketolase activity in epithelial cells of different rat tissues and subcellularly in liver parenchymal cells.
Increased expression of transketolase-like-1 in papillary thyroid carcinomas smaller than 1.5 cm in diameter is associated with lymph-node metastases.
Inhibition of protein phosphorylation in MIA pancreatic cancer cells: confluence of metabolic and signaling pathways.
Is transketolase like 1 a target for the treatment of differentiated thyroid carcinoma? A study on thyroid cancer cell lines.
Is transketolase-like protein, TKTL1, transketolase?
Knockdown of TKTL1 additively complements cisplatin-induced cytotoxicity in nasopharyngeal carcinoma cells by regulating the levels of NADPH and ribose-5-phosphate.
Lack of transketolase-like (TKTL) 1 aggravates murine experimental colitis.
Long Noncoding RNA TSLNC8 Is a Tumor Suppressor that Inactivates the IL-6/STAT3 Signaling Pathway.
Mechanical insights of oxythiamine compound as potent inhibitor for human transketolase-like protein 1 (TKTL1 protein).
Metastasis is promoted by a bioenergetic switch: new targets for progressive renal cell cancer.
Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer.
Non-charged thiamine analogs as inhibitors of enzyme transketolase.
Nonoxidative pentose phosphate pathways and their direct role in ribose synthesis in tumors: is cancer a disease of cellular glucose metabolism?
Overexpression of transketolase protein TKTL1 is associated with occurrence and progression in nasopharyngeal carcinoma: A potential therapeutic target in nasopharyngeal carcinoma.
Oxythiamine and dehydroepiandrosterone induce a G1 phase cycle arrest in Ehrlich's tumor cells through inhibition of the pentose cycle.
Oxythiamine and dehydroepiandrosterone inhibit the nonoxidative synthesis of ribose and tumor cell proliferation.
Population thiamine status and varying cancer rates between western, Asian and African countries.
Prodrug thiamine analogs as inhibitors of the enzyme transketolase.
Prognostic values of transketolase family genes in ovarian cancer.
Proteomic-based biosignatures in breast cancer classification and prediction of therapeutic response.
Proteomics analysis of differentially expressed metastasis-associated proteins in adenoid cystic carcinoma cell lines of human salivary gland.
Rationale, Feasibility and Acceptability of Ketogenic Diet for Cancer Treatment.
Role of thiamin (vitamin B-1) and transketolase in tumor cell proliferation.
Silencing of TKTL1 by siRNA inhibits proliferation of human gastric cancer cells in vitro and in vivo.
Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors.
The development of tumours under a ketogenic diet in association with the novel tumour marker TKTL1: A case series in general practice.
The effect of thiamine supplementation on tumour proliferation. A metabolic control analysis study.
The human transketolase-like proteins TKTL1 and TKTL2 are bona fide transketolases.
The nuclear translocation of transketolase inhibits the farnesoid receptor expression by promoting the binding of HDAC3 to FXR promoter in hepatocellular carcinoma cell lines.
The role of glucose metabolism and glucose-associated signalling in cancer.
The role of thiamine in cancer: possible genetic and cellular signaling mechanisms.
The thiamine status of patients with cancer as determined by the red cell transketolase activity.
Thiamine metabolism in the liver of mice with Ehrlich ascites carcinoma.
Thiamine supplementation to cancer patients: a double edged sword.
TKTL1 and p63 are biomarkers for the poor prognosis of gastric cancer patients.
TKTL1 expression and its downregulation is implicated in cell proliferation inhibition and cell cycle arrest in esophageal squamous cell carcinoma.
TKTL1 expression in human malign and benign cell lines.
TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization.
TKTL1 is overexpressed in a large portion of non-small cell lung cancer specimens.
TKTL1 modulates the response of paclitaxel-resistant human ovarian cancer cells to paclitaxel.
TKTL1 promotes cell proliferation and metastasis in esophageal squamous cell carcinoma.
Transketolase counteracts oxidative stress to drive cancer development.
Transketolase protein TKTL1 overexpression: A potential biomarker and therapeutic target in breast cancer.
Transketolase regulates the metabolic switch to control breast cancer cell metastasis via the alpha-ketoglutarate signaling pathway.
Transketolase-like 1 ectopic expression is associated with DNA hypomethylation and induces the Warburg effect in melanoma cells.
Transketolase-like 1 expression correlates with subtypes of ovarian cancer and the presence of distant metastases.
Transketolase-like 1 expression is modulated during colorectal cancer progression and metastasis formation.
Transketolase-like protein 1 (TKTL1) is required for rapid cell growth and full viability of human tumor cells.
Transketolase-Like Protein 1 and Glucose Transporter 1 in Gastric Cancer.
Transketolase-like protein 1 confers resistance to serum withdrawal in vitro.
Transketolase-like protein 1 expression in recurrent oral squamous cell carcinoma after curative resection: a case report.
Transketolase-like protein 1 expression predicts poor prognosis in colorectal cancer.
Tumor-associated metabolic and inflammatory responses in early stage non-small cell lung cancer: Local patterns and prognostic significance.
Vitamin B 1, B 2 and B 6 deficiency in neurological disorders.
[Activities of dehydrogenases of the pentose phosphate pathway and transketolase in transplanted mouse hepatomas with different growth rates and in organs of tumor carriers]
[Analysis of differentially expressed lung metastasis-associated proteins in adenoid cystic carcinoma cell lines]
[Effect of thiamine and its antimetabolite oxythiamine on the proliferative activity of carcinosarcoma Walker 256 cells]
[Expression and clinical significance of MTDH, HIF-1? and TKTL1 in laryngeal carcinoma].
[The effect of oxythiamine on tumor growth and certain biochemical and genetic characteristics of normal and tumor cells]
[Transketolase activity and the TDP effect in tissues of animals with experimental tumors]
[Transketolase activity and thiamine diphosphate content in oncological patients]
[Transketolase activity in some transplantable tumors in mice.]
[Tumor and body interrelationships in 14C-thiamine utilization]
Neoplasms, Experimental
[Thiamine content of tissues, activity of transketolase and development of experimental neoplasms with different thiamine allowances]
Nervous System Diseases
Occurrence of transketolase abnormalities in extracts of foreskin fibroblasts from patients with Alzheimer's disease.
Vitamin B 1, B 2 and B 6 deficiency in neurological disorders.
Neuritis
The transketolase assay of thiamine in some diseases.
Neuroblastoma
Sensitivity to thiamine deficiency in cultured human cells is dependent on cell type and is enhanced in cells from thiamine-responsive megaloblastic anemia patients.
Neurodegenerative Diseases
Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer.
Nutrition Disorders
BLOOD TRANSKETOLASE DETERMINATION IN NUTRITIONAL DISORDERS OF THE NERVOUS SYSTEM.
Obesity
Attenuated metabolism is a hallmark of obesity as revealed by comparative proteomic analysis of human omental adipose tissue.
Fasting in obesity. Thiamine depletion as measured by erythrocyte transketolase changes.
Transketolase Deficiency in Adipose Tissues Protects Mice From Diet-Induced Obesity by Promoting Lipolysis.
Ovarian Neoplasms
Prognostic values of transketolase family genes in ovarian cancer.
TKTL1 modulates the response of paclitaxel-resistant human ovarian cancer cells to paclitaxel.
Transketolase is upregulated in metastatic peritoneal implants and promotes ovarian cancer cell proliferation.
Transketolase-like 1 expression correlates with subtypes of ovarian cancer and the presence of distant metastases.
Pancreatic Neoplasms
Fructose induces transketolase flux to promote pancreatic cancer growth.
Inhibition of protein phosphorylation in MIA pancreatic cancer cells: confluence of metabolic and signaling pathways.
Inhibition of transketolase by oxythiamine altered dynamics of protein signals in pancreatic cancer cells.
Parasitic Diseases
The vitamin B1 status among young Egyptian males in relation to infection with parasites.
Peripheral Nervous System Diseases
The haematic thiamine level in the course of alcoholic neuropathy.
Transketolase inhibition and uremic peripheral sensory neuropathy.
Pneumonia
[Transketolase activity in infants with pneumonia]
Polymyositis
Muscle transketolase in normal foetuses and Duchenne dystrophy.
Polyneuropathies
Association of transketolase polymorphisms with measures of polyneuropathy in patients with recently diagnosed diabetes.
Primary Dysautonomias
Altered Heavy Metals and Transketolase Found in Autistic Spectrum Disorder.
The role of trace elements, thiamin (e) and transketolase in autism and autistic spectrum disorder.
Prostatic Neoplasms
Effect of radical prostatectomy on levels of cancer related epitopes in circulating macrophages of patients with clinically localized prostate cancer.
Evaluation of TKTL1 as a biomarker in serum of prostate cancer patients.
Transketolase like 1 (TKTL1) expression alterations in prostate cancer tumorigenesis.
Protein-Energy Malnutrition
Erythrocyte transketolase activity in protein-energy malnutrition.
Pseudorabies
Motor neuron degeneration in a horse.
Psoriasis
[On methods for determination of transketolase in the skin of patients with psoriasis]
[Transketolase activity as a parameter for the vitamin B1 provision in some dermatoses (herpes zoster, psoriasis, drug eruptions, excema, and urticaria) (author's transl)]
Rectal Neoplasms
Expression of Transketolase like gene 1 (TKTL1) predicts disease-free survival in patients with locally advanced rectal cancer receiving neoadjuvant chemoradiotherapy.
Renal Insufficiency, Chronic
Erythrocyte transketolase activity in patients with chronic renal disease.
Rheumatic Diseases
[Use of glucose-6-phosphate dehydrogenase and transketolase for characterization of pathologic processes in the myocardium in rheumatism]
Riboflavin Deficiency
Effect of simultaneous thiamin and riboflavin deficiencies on the determination of transketolase and glutathione reductase.
Sarcoma
High-performance liquid chromatography/nano-electrospray ionization tandem mass spectrometry, two-dimensional difference in-gel electrophoresis and gene microarray identification of lymphatic metastasis-associated biomarkers.
[Transketolase activity and the TDP effect in tissues of animals with experimental tumors]
[Transketolase activity in Galliera sarcoma.]
Seizures
Activities of thiamine-dependent enzymes in two experimental models of thiamine-deficiency encephalopathy: 1. The pyruvate dehydrogenase complex.
Multiple causes of asphyxia in infants at high risk for sudden infant death.
Skin Diseases
[Transketolase activity as a parameter for the vitamin B1 provision in some dermatoses (herpes zoster, psoriasis, drug eruptions, excema, and urticaria) (author's transl)]
Small Cell Lung Carcinoma
TKTL-1 expression in lung cancer.
Squamous Cell Carcinoma of Head and Neck
c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation.
EDIM-TKTL1/Apo10 Blood Test: An Innate Immune System Based Liquid Biopsy for the Early Detection, Characterization and Targeted Treatment of Cancer.
TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization.
Transketolase-like protein 1 confers resistance to serum withdrawal in vitro.
Starvation
Action of thiamine on protein and nucleic acid metabolism, III. Transketolase activity of Lactobacillus viridescens during thiamine starvation.
Behavior of transaldolase (EC 2.2.1.2) and transketolase (EC 2.2.1.1) Activities in normal, neoplastic, differentiating, and regenerating liver.
Stomach Neoplasms
Expression of the mutated transketolase TKTL1, a molecular marker in gastric cancer.
Silencing of TKTL1 by siRNA inhibits proliferation of human gastric cancer cells in vitro and in vivo.
TKTL1 and p63 are biomarkers for the poor prognosis of gastric cancer patients.
Transketolase-Like Protein 1 and Glucose Transporter 1 in Gastric Cancer.
[Transketolase activity and thiamine diphosphate content in oncological patients]
Thiamine Deficiency
Abnormalities of peripheral nerve conduction in relation to thiamine status in alcoholic patients.
Absorption, utilization and clinical effectiveness of allithiamines compared to water-soluble thiamines.
Acute encephalopathy due to thiamine deficiency (Wernicke's encephalopathy) in a chronic hemodialyzed patient: a case report.
Alcohol intakes and deficiencies in thiamine and vitamin B6 in black patients with cardiac failure.
Blood thiamine levels in outpatients with diabetes mellitus.
Blood transketolase in assessment of thiamine deficiency in alcoholics.
Cardiac Beriberi: Often a Missed Diagnosis.
Chronic toxicity of dichloroacetate: possible relation to thiamine deficiency in rats.
Clinical evaluation and biochemical analyses of thiamine deficiency in Pacific harbor seals (Phoca vitulina) maintained at a zoological facility.
Clinical relevance of thiamine status amongst hospitalized elderly patients.
Cloning of human transketolase cDNAs and comparison of the nucleotide sequence of the coding region in Wernicke-Korsakoff and non-Wernicke-Korsakoff individuals.
Decreased transketolase activity contributes to impaired hippocampal neurogenesis induced by thiamine deficiency.
Detection and incidence of B and C vitamin deficiency in alcohol-related illness.
Downregulation of transketolase activity is related to inhibition of hippocampal progenitor cell proliferation induced by thiamine deficiency.
Effect of peroral thiamine treatment on thiamine contents and transketolase activity of red blood cells in alcoholic patients.
Effect of thiamine deficiency on gluconeogenesis and transketolase activity in isolated hepatocytes.
Effects of thiamine deficiency and of oxythiamine on rat tissue transketolase.
Erythrocyte transketolase activity in alcoholic liver disease.
Erythrocyte transketolase in early thiamine deficiency.
Glycolytic metabolism in cultured cells of the nervous system. IV. The effects of thiamine deficiency on thiamine levels, metabolites and thiamine-dependent enzymes on the C-6 glioma and C-1300 neuroblastoma cell lines.
In thiamine deficiency, activation of erythrocyte transketolase by thiamine in vivo exceeds activation by cofactor in vitro.
Individual susceptibility to Wernicke-Korsakoff syndrome and alcoholism-induced cognitive deficit: impaired thiamine utilization found in alcoholics and alcohol abusers.
Kinetic studies of mouse brain transketolase.
Lactic acidosis in thiamine deficiency.
Lead induced thiamine deficiency in the brain decreased the threshold of electroshock seizure in rat.
Outbreak of life-threatening thiamine deficiency in infants in Israel caused by a defective soy-based formula.
Oxalate metabolism in thiamine-deficient rats.
Peripheral neuropathy and myopathy. An experimental study of rats on alcohol and variable dietary thiamine.
Polioencephalomalacia (cerebrocortical necrosis) induced by experimental thiamine deficiency in lambs.
Postpartum thiamine deficiency in a Karen displaced population.
Reappearance of beriberi heart disease in Japan. A study of 23 cases.
Reduced activities of thiamine-dependent enzymes in brains of alcoholics in the absence of Wernicke's encephalopathy.
Reduced sensory and motor nerve conduction velocities in moderate drinkers.
Shoshin Beriberi Mimicking a High-risk Non-ST-Segment Elevation Acute Coronary Syndrome with Cardiogenic Shock: When the Arteries are Not Guilty.
The effect of thiaminase-induced subclinical thiamine deficiency on growth of weaner sheep.
The relationship between erythrocyte transketolase activity and the 'TPP effect' in Wernicke's encephalopathy and other thiamine deficiency states.
The thiamine-dependent hysteretic behavior of human transketolase: implications for thiamine deficiency.
The uremic toxin oxythiamine causes functional thiamine deficiency in end-stage renal disease by inhibiting transketolase activity.
Thiamine and magnesium deficiencies: keys to disease.
Thiamine deficiency and malaria in adults from southeast Asia.
Thiamine deficiency and the etiology of tropical ataxic neuropathy.
Thiamine deficiency and Wernicke's encephalopathy in AIDS.
Thiamine deficiency decreases steady-state transketolase and pyruvate dehydrogenase but not alpha-ketoglutarate dehydrogenase mRNA levels in three human cell types.
Thiamine deficiency in a cat: resolution of MRI abnormalities following thiamine supplementation.
Thiamine deficiency in Gambian women of reproductive age.
Thiamine pyrophosphate effect and normalized erythrocyte transketolase activity ratio in Wernicke-Korsakoff patients and acute alcoholics undergoing detoxification.
Thiamine pyrophosphate-requiring enzymes are altered during pyrithiamine-induced thiamine deficiency in cultured human lymphoblasts.
Thiamine status after major trauma.
Thiamine transporter 2 is involved in high glucose-induced damage and altered thiamine availability in cell models of diabetic retinopathy.
Thiamine utilization in the pathogenesis of alcohol-induced brain damage.
Transketolase abnormality in cultured fibroblasts from familial chronic alcoholic men and their male offspring.
TRANSKETOLASE ACTIVITY IN EXPERIMENTAL THIAMINE DEFICIENCY AND HEPATIC NECROSIS.
Transketolase activity in the blood of cattle and sheep in relation to thiamine deficiency.
Transketolase activity of blood hemolysate, a useful index for diagnosing thiamine deficiency.
Transketolase variant enzymes and brain damage.
Treatment of autism spectrum children with thiamine tetrahydrofurfuryl disulfide: a pilot study.
[Analysis of the daily human requirements for thiamine in the newly arrived population of Polar regions]
[Enzyme-histochemical behaviour of the tanycyte ependyma in the III. ventricle of the rat with thiamin deficiency (author's transl)]
[Importance of water-soluble vitamins as regulatory factors of genetic expression]
[Interstitial thiamine redistribution during the development of vitamin B1 deficiency in mice]
[Thiamine deficiency in chronic alcoholism. The effect of thiamine treatment on the erythrocyte transketolase activity and the thiamine pyrophosphate effect]
[Transketolase activity and the TDP effect in tissues of animals with experimental tumors]
[Transketolase activity in thiamine deficiency of the kidney in rainbow trout (Salmo gairdneri) following continous feeding with raw hearring]
[Transketolase activity of erythrocytes of chronic alcoholic patients with assumed thiamine deficiency]
[Transketolase test: a means for the diagnosis of subclinical and clinical thiamine deficiency in cattle]
[Ultrastructure of the rat gastric mucosal parietal cells in thiamine deficiency]
[Use of the colorimetric micromethod for determination of erythrocyte transketolase activity in the enzyme test for detection of thiamine deficiency]
[Vitamin B 1 deficiency in chronic alcoholics and its clinical correlation]
Thyroid Cancer, Papillary
Increased expression of transketolase-like-1 in papillary thyroid carcinomas smaller than 1.5 cm in diameter is associated with lymph-node metastases.
Thyroid Carcinoma, Anaplastic
Dual effects for lovastatin in anaplastic thyroid cancer: the pivotal effect of transketolase (TKT) on lovastatin and tumor proliferation.
Thyroid Neoplasms
Is transketolase like 1 a target for the treatment of differentiated thyroid carcinoma? A study on thyroid cancer cell lines.
Targeting the pentose phosphate pathway increases reactive oxygen species and induces apoptosis in thyroid cancer cells.
transaldolase deficiency
Untargeted metabolomics as an unbiased approach to the diagnosis of inborn errors of metabolism of the non-oxidative branch of the pentose phosphate pathway.
transketolase deficiency
Erythrocyte transketolase deficiency in patients suffering from Crohn's disease.
Mutations in TKT Are the Cause of a Syndrome Including Short Stature, Developmental Delay, and Congenital Heart Defects.
Transketolase Deficiency in Adipose Tissues Protects Mice From Diet-Induced Obesity by Promoting Lipolysis.
Transketolase Deficiency Protects the Liver from DNA Damage by Increasing Levels of Ribose 5-Phosphate and Nucleotides.
Untargeted metabolomics as an unbiased approach to the diagnosis of inborn errors of metabolism of the non-oxidative branch of the pentose phosphate pathway.
Tuberculosis
Assessing essentiality of transketolase in Mycobacterium tuberculosis using an inducible protein degradation system.
Biosynthesis of D-arabinose in mycobacteria - a novel bacterial pathway with implications for antimycobacterial therapy.
Molecular analysis of the Corynebacterium glutamicum transketolase gene.
Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme.
Structure-activity relationships of compounds targeting mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate synthase.
Tuberous Sclerosis
Malignant pleural effusion cells show aberrant glucose metabolism gene expression.
Uremia
Comparison of the thiamine level in blood and erythrocyte transketolase activity in hemodialyzed and nondialyzed patients during recombinant human erythropoietin therapy.
Erythrocyte transketolase activity in dialyzed patients. A reversible metabolic lesion of uremia.
Erythrocyte transketolase activity in uremia.
Erythrocyte transketolase inhibition, neuropathy and uremia.
Relationship of nervous tissue transketolase to the neuropathy in chronic uremia.
Transketolase activity in red blood cells in chronic uremia.
Transketolase activity in uremia.
Water soluble vitamins in chronic hemodialysis patients and need for supplementation.
Urinary Bladder Neoplasms
Expression patterns and prognostic role of transketolase-like 1 in muscle-invasive bladder cancer.
Uterine Cervical Neoplasms
MicroRNA-497 regulates cisplatin chemosensitivity of cervical cancer by targeting transketolase.
Overexpression of transketolase-like gene 1 is associated with cell proliferation in uterine cervix cancer.
Vascular Diseases
The transketolase assay of thiamine in some diseases.
Virus Diseases
Cross-protective efficacy of bivalent recombinant baculoviral vaccine against heterologous influenza H5N1 challenge.
[Metabolic aspects of hepatic tissue in MHV-3 virus infections of the mouse. I. Transketolase, glucose-6-phosphate-dehydrogenase, 6-phosphogluconic-dehydrogenase.]
Vitamin B 6 Deficiency
Detection and incidence of B and C vitamin deficiency in alcohol-related illness.
Wernicke Encephalopathy
Alcohol-thiamine interactions: an update on the pathogenesis of Wernicke encephalopathy.
Current progress toward the prevention of the Wernicke-Korsakoff syndrome.
The relationship between erythrocyte transketolase activity and the 'TPP effect' in Wernicke's encephalopathy and other thiamine deficiency states.
Transketolase abnormality in tolazamide-induced Wernicke's encephalopathy.
Wernicke's Encephalopthy Associated with Hyperemesis Gravidarum - A Case Report.
Wilms Tumor
Anaplastic nephroblastomas express transketolase-like enzyme 1.