Information on EC 2.3.1.113 - anthranilate N-malonyltransferase

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The expected taxonomic range for this enzyme is: Arachis hypogaea

EC NUMBER
COMMENTARY hide
2.3.1.113
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RECOMMENDED NAME
GeneOntology No.
anthranilate N-malonyltransferase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
malonyl-CoA + anthranilate = CoA + N-malonylanthranilate
show the reaction diagram
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-
-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Acyl group transfer
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-
-
-
SYSTEMATIC NAME
IUBMB Comments
malonyl-CoA:anthranilate N-malonyltransferase
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CAS REGISTRY NUMBER
COMMENTARY hide
94489-98-2
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
peanut, cv. fastigiata ('Junagarh-11' or cultivar Shulamit)
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-
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
malonyl-CoA + anthranilate
CoA + N-malonylanthranilate
show the reaction diagram
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-
-
?
additional information
?
-
-
no substrates are D-tryptophan and 3,4-dichloroaniline
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-
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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
bovine serum albumin
-
2 mg/ml, activation
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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.012
anthranilate
-
-
0.004
malonyl-CoA
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-
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.00091
-
-
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
8.8
-
broad
pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
7.5 - 9
-
most active
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
30
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assay at
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
50000
-
gel filtration
SUBUNITS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
monomer
-
1 * 51000, SDS-PAGE
STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
-20°C, inactivtion after 3 months
-
4°C, considerable loss of activity after several weeks
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glycerol, 10%, stabilizes during storage
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Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE