Information on EC 2.3.1.14 - glutamine N-phenylacetyltransferase

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
2.3.1.14
-
RECOMMENDED NAME
GeneOntology No.
glutamine N-phenylacetyltransferase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
phenylacetyl-CoA + L-glutamine = CoA + alpha-N-phenylacetyl-L-glutamine
show the reaction diagram
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Acyl group transfer
-
-
-
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
L-phenylalanine degradation IV (mammalian, via side chain)
-
-
Tyrosine metabolism
-
-
Phenylalanine metabolism
-
-
SYSTEMATIC NAME
IUBMB Comments
phenylacetyl-CoA:L-glutamine alpha-N-phenylacetyltransferase
-
CAS REGISTRY NUMBER
COMMENTARY hide
9030-00-6
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
-
Manually annotated by BRENDA team
monkey
-
-
Manually annotated by BRENDA team
no activity in Canis sp.
dog
-
-
Manually annotated by BRENDA team
no activity in Equus sp.
horse
-
-
Manually annotated by BRENDA team
no activity in Felis sp.
cat
-
-
Manually annotated by BRENDA team
no activity in Macaca fuscata
monkey
-
-
Manually annotated by BRENDA team
no activity in Oryctolagus cuniculus
rabbit
-
-
Manually annotated by BRENDA team
no activity in Ovis aries
sheep
-
-
Manually annotated by BRENDA team
no activity in Rattus norvegicus
rat
-
-
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
benzoyl-CoA + glycine
CoA + benzoylglycine
show the reaction diagram
phenylacetyl-CoA + glycine
CoA + phenylacetylglycine
show the reaction diagram
phenylacetyl-CoA + L-glutamine
CoA + alpha-N-phenylacetyl-L-glutamine
show the reaction diagram
-
-
-
?
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
phenylacetyl-CoA + L-glutamine
CoA + alpha-N-phenylacetyl-L-glutamine
show the reaction diagram
-
-
-
?
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
-
specific activity in various organs
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
8.8 - 10
-
-
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
37.5
-
assay at
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
additional information
-
no activity in heart and lung
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
30000
-
gel filtration
GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
50% loss of activity after lyophilization
-
STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
-15°C, stable for several months
-
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
partial