Reference on EC 2.3.2.2 - gamma-glutamyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Yoshida, K.I.; Arai, K.; Kobayashi, N.; Saitoh, H.
Purification and properties of gamma-glutamyl transpeptidase from human testis
Andrologia
22
239-246
1990
Homo sapiens
Arai, K.; Yoshida, K.; Komoda, T.; Sakagishi, Y.
Comparative studies on the properties of purified gamma-glutamyl transferase from human reproductive system and the kidney
Clin. Biochem.
23
105-112
1990
Homo sapiens
Kimm, S.W.; Kim, E.G.; Park, S.C.
Partial purification and characterization of gamma-glutamyl transpeptidase from rat kidney
Korean J. Biochem.
18
135-143
1986
Rattus norvegicus
-
Glynn, B.P.; Johnson, D.B.
gamma-Glutamyltransferase from Marthasterias glacialis: purifiication procedures and enzyme characterization
Comp. Biochem. Physiol. B
80
941-948
1985
Marthasterias glacialis
Sugimoto, M.; Yamaguchi, N.; Keiichi, K.
Characterization of gamma-GTP in a human pancreatic cancer cell line
Gastroenterol. Jpn.
19
227-231
1984
Homo sapiens
Vesely, J.; Cernoch, M.
Solubilization and some properties of gamma-glutamyltransferase from human brain microvessels
Neurochem. Res.
9
927-934
1984
Homo sapiens
Rambabu, K.; Pattabiraman, T.N.
Studies on the properties of the variants of gamma-glutamyl transpeptidase in human urine
J. Biosci.
4
287-294
1982
Homo sapiens
-
Masuike, M.; Ogawa, M.; Kosaki, G.; Minamiura, N.; Yamamoto, T.
Purification and characterization of gamma-glutamyl transpeptidase from human pancreas
Enzyme
27
163-170
1982
Homo sapiens
Frielle, T.; Curthoys, N.P.
Characterization of the amphipathic structure of gamma-glutamyltranspeptidase F13
Biophys. J.
37
193-195
1982
Rattus norvegicus
Echetebu, Z.O.; Moss, D.W.
Multiple forms of human gamma-glutamyltransferase: preparation and characterization of different molecular weight fractions
Enzyme
27
1-8
1982
Homo sapiens
Nakamura, Y.; Kato, H.; Suzuki, F.; Nagata, Y.
Some properties of gamma-glutamyltransferase from hog small intestine
Biomed. Res.
2
509-516
1981
Sus scrofa
-
Hata, K.; Hayakawa, M.; Abiko, Y.; Takiguchi, H.
Purification and properties of gamma-glutamyl transpeptidase from bovine parotid gland
Int. J. Biochem.
13
681-692
1981
Bos taurus
Tsuji, A.; Matsuda, Y.; Katunuma, N.
Characterization of human serum gamma-glutamyltranspeptidase
Clin. Chim. Acta
104
361-364
1980
Homo sapiens
Baumrucker, C.R.
Purification and identification of gamma-glutamyl transpeptidase of milk membranes
J. Dairy Sci.
63
49-54
1980
Bos taurus
Das, N.D.; Shichi, H.
gamma-Glutamyl transpeptidase of bovine ciliary body: purification and properties
Exp. Eye Res.
29
109-121
1979
Bos taurus
Tsuchida, S.; Hoshino, K.; Sato, T.; Ito, N.
Purification of gamma-glutamyltransferases from rat hepatomas and hyperplastic hepatic nodules, and comparison with the enzyme from rat kidney
Cancer Res.
39
4200-4205
1979
Rattus norvegicus
Taniguchi, N.
Purification and some properties of gamma-glutamyl transpeptidase from azo dye-induced hepatoma
J. Biochem.
75
473-480
1974
Rattus norvegicus
Jaken, S.; Mason, M.
Purification and comparison of several catalytic parameters of the gamma-glutamyltranspeptidase of rat mammary adenocarcinoma (13762) and of normal rat mammary gland
Biochim. Biophys. Acta
568
331-338
1979
Rattus norvegicus
Ding, J.L.; Smith, G.D.; Peters, T.J.
The purification of gamma-glutamyltransferase from normal rat liver
Biochem. Soc. Trans.
8
77
1980
Rattus norvegicus, Rattus norvegicus Wistar
Horiuchi, S.; Inoue, M.; Morino, Y.
Latent active site in rat-kidney gamma-glutamyl transpeptidase. The refolding process of the large subunit and characterization of the renatured enzyme
Eur. J. Biochem.
105
93-102
1980
Rattus norvegicus, Rattus norvegicus Wistar
Ding, J.L.; Smith, G.D.; Peters, T.J.
Purification and properties of gamma-glutamyl transferase from normal rat liver
Biochim. Biophys. Acta
657
334-343
1981
Rattus norvegicus
Sachdev, G.P.; Leahy, D.S.; Chace, K.V.
Phenobarbital and related compounds as novel inhibitors of gamma-glutamyltranspeptidase
Biochim. Biophys. Acta
749
125-129
1983
Rattus norvegicus
Takahashi, S.; Steinman, H.M.; Ball, D.
Purification and characterization of gamma-glutamyltransferase from rat pancreas
Biochim. Biophys. Acta
707
66-73
1982
Rattus norvegicus, Rattus norvegicus Wistar
Tarachand, U.
Purification and properties of gamma-glutamyl transpeptidase from rat deciduoma
J. Appl. Biochem.
6
278-288
1984
Rattus norvegicus
Bagrel, D.; Petitclerc, C.; Schiele, F.; Siest, G.
Some kinetic properties of gamma-glutamyltransferase from rabbit liver
Biochim. Biophys. Acta
658
220-231
1981
Oryctolagus cuniculus, Oryctolagus cuniculus Fauve de Bourgogne
Franois, C.; Calberg-Bacq, C.M.; Gosselin, L.; Kozma, S.; Osterrieth, P.M.
Identification, partial purification and biochemical characterization of gamma-glutamyltranspeptidase present as a membrane component in skimmed milk and milk fat-globule membranes, and in mammary-tumour virus from the milk of infected mice
Biochim. Biophys. Acta
567
106-115
1979
Mus musculus, Oncornavirus
Yasumoto, K.; Iwami, K.; Fushiki, T.; Mitsuda, H.
Purification and enzymatic properties of gamma-glutamyltransferase from bovine colostrum
J. Biochem.
84
1227-1236
1978
Bos taurus
Furukawa, M.; Higashi, T.; Tateishi, N.; Ochi, K.; Sakamoto, Y.
Purification and properties of bovine liver gamma-glutamyltransferase
J. Biochem.
93
839-846
1983
Bos taurus
Karkowsky, A.M.; Bergamini, M.V.W.; Orlowski, M.
Kinetic studies of sheep kidney gamma-glutamyl transpeptidase
J. Biol. Chem.
251
4736-4743
1976
Ovis aries
Zelazo, P.; Orlowski, M.
gamma-Glutamyl transpeptidase of sheep-kidney cortex. Isolation, catalytic properties and dissociation into two polypeptide chains
Eur. J. Biochem.
61
147-155
1976
Ovis aries
Leibach, F.H.; Binkley, F.
gamma-Glutamyl transferase of swine kidney
Arch. Biochem. Biophys.
127
292-301
1968
Sus scrofa
-
rning, L.; Hammarstrm, S.
Kinetics of the conversion of leukotriene C by gamma-glutamyl transpeptidase
Biochem. Biophys. Res. Commun.
106
1304-1309
1982
Sus scrofa
Bernstrm, K.; Orning, L.; Hammarstrm, S.
gamma-Glutamyl transpeptidase, a leukotriene metabolizing enzyme
Methods Enzymol.
86
38-45
1982
Rattus norvegicus, Sus scrofa
Allison, D.
gamma-Glutamyl transpeptidase: kinetics and mechanism
Methods Enzymol.
113
419-437
1985
Mammalia, Mus musculus, Ovis aries, Rattus norvegicus
Tate, S.S.; Meister, A.
gamma-Glutamyl transpeptidase from kidney
Methods Enzymol.
113
400-419
1985
Mammalia, Mus musculus, Rattus norvegicus
Shaw, L.M.
gamma-Glutamyltransferase. (gamma-Glutamyl)-peptide:amino acid gamma-glutamyltransferase, EC 2.3.2.2. 1. General
Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. )
3
349-352
1983
Oryctolagus cuniculus, Homo sapiens, Rattus norvegicus
-
Wahlefeld, A.W.; Bergmeyer, H.U.
gamma-Glutamyltransferase. (gamma-Glutamyl)-peptide:amino acid gamma-glutamyltransferase, EC 2.3.2.2. 2. Routine method
Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. )
3
352-356
1983
Homo sapiens
-
Shaw, L.M.; Stromme, J.H.
gamma-Glutamyltransferase. (gamma-Glutamyl)-peptide:amino acid gamma-glutamyltransferase, EC 2.3.2.2. 3. IFCC reference method (provisional)
Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. )
3
357-364
1983
Homo sapiens
-
Takahashi, S.; Zukin, R.S.; Steinman, H.M.
gamma-Glutamyl transpeptidase from WI-38 fibroblasts: purification and active site modification studies
Arch. Biochem. Biophys.
207
87-95
1981
Homo sapiens
Cook, N.D.; Peters, T.J.
Purification of gamma-glutamyltransferase by phenyl boronate affinity chromatography. Studies on the acceptor specificity of transpeptidation by rat kidney gamma-glutamyltransferase
Biochim. Biophys. Acta
828
205-212
1985
Rattus norvegicus
Miller, S.P.; Awasthi, Y.C.; Srivastava, S.K.
Studies of human kidney gamma-glutamyl transpeptidase. Purification and structural, kinetic and immunological properties
J. Biol. Chem.
251
2271-2278
1976
Homo sapiens
Tate, S.S.; Ross, M.E.
Human kidney gamma-glutamyl transpeptidase. Catalytic properties, subunit structure, and localization of the gamma-glutamyl binding site on the light subunit
J. Biol. Chem.
252
6042-6045
1977
Homo sapiens, Rattus norvegicus
Yamashita, K.; Totani, K.; Iwaki, Y.; Takamisawa, I.; Tateishi, N.; Higashi, T.; Sakamoto, Y.; Kobata, A.
Comparative study of the sugar chains of gamma-glutamyltranspeptidases purified from human hepatocellular carcinoma and from human liver
J. Biochem.
105
728-735
1989
Homo sapiens
Abe, S.; Kochi, H.; Hiraiwa, K.
Purification and immunological characterization of a new form of gamma-glutamyltransferase of human semen
Biochim. Biophys. Acta
1077
259-264
1991
Homo sapiens
Huseby, N.
Purification and some properties of gamma-glutamyltransferase from human liver
Biochim. Biophys. Acta
483
46-56
1977
Homo sapiens
Indirani, N.; Hill, P.G.
Partial purification and some properties of gamma-glutamyl transpeptidase from human bile
Biochim. Biophys. Acta
483
57-62
1977
Homo sapiens
Ogawa, Y.; Hosoyama, H.; Hamano, M.; Motai, H.
Purification and properties of gamma-glutamyltranspeptidase from Bacillus subtilis (natto)
Agric. Biol. Chem.
55
2971-2977
1991
Bacillus subtilis
Suzuki, H.; Kumagai, H.; Tochikura, T.
gamma-Glutamyltranspeptidase from Escherichia coli K-12: purification and properties
J. Bacteriol.
168
1325-1331
1986
Escherichia coli
Suzuki, H.; Kumagai, H.; Tochikura, T.
gamma-Glutamyltranspeptidase from Escherichia coli K-12: formation and localization
J. Bacteriol.
168
1332-1335
1986
Escherichia coli
Nakayama, R.; Kumagai, H.; Tochikura, T.
Purification and properties of gamma-glutamyltranspeptidase from Proteus mirabilis
J. Bacteriol.
160
341-346
1984
Proteus mirabilis
Iwami, K.; Yasumoto, K.; Nakamura, K.; Mitsuda, H.
Properties of gamma-glutamyltransferase from Lentinus edodes
Agric. Biol. Chem.
39
1933-1940
1975
Lentinula edodes
-
Iwami, K.; Yasumoto, K.; Nakamura, K.; Mitsuda, H.
Reactivity of Lentinus gamma-glutamyltransferase with lentinic acid as the principal endogenous substrate
Agric. Biol. Chem.
39
1941-1946
1975
Lentinula edodes
-
Minato, S.
Isolation of anthglutin, an inhibitor of gamma-glutamyl transpeptidase from Penicillum oxalicum
Arch. Biochem. Biophys.
192
235-240
1979
Canis lupus familiaris, Homo sapiens
Tomita, K.; Yano, T.; Tsuchida, T.; Kumagai, H.; Tochikura, T.
Purification and properties of gamma-glutamyltranspeptidase from Penicillium roqueforti IFO 4622
J. Ferment. Bioeng.
70
128-130
1990
Penicillium roqueforti, Penicillium roqueforti IFO 4622
-
Moriguchi, M.; Yamada, M.; Suenaga, S.; Tanaka, H.; Wakasugi, A.; Hatanaka, S.I.
Partial purification and properties of gamma-glutamyltranspeptidase from mycelia of Morchella esculenta
Arch. Microbiol.
144
15-19
1986
Morchella esculenta
Penninckx, M.J.; Jaspers, C.J.
Molecular and kinetic properties of purified gamma-glutamyl transpeptidase from yeast (Saccharomyces cerevisiae)
Phytochemistry
24
1913-1918
1985
Saccharomyces cerevisiae, Saccharomyces cerevisiae 1278b
-
Tomita, K.; Ito, M.; Yano, T.; Kumagai, H.; Tochikura, T.
gamma-Glutamyltranspeptidase activity and the properties of the extracellular glutaminase from Aspergillus oryzae
Agric. Biol. Chem.
52
1159-1163
1988
Aspergillus oryzae, Aspergillus oryzae MA-27-IM
-
Goore, M.Y.; Thompson, J.F.
gamma-Glutamyl transpeptidase from kidney bean fruit. I. Purification and mechanism of action
Biochim. Biophys. Acta
132
15-26
1967
Phaseolus vulgaris
Goore, M.Y.; Thompson, J.F.
gamma-Glutamyl transpeptidase of kidney bean fruit. II. Studies on the activating effect of sodium citrate
Biochim. Biophys. Acta
132
27-32
1967
Phaseolus vulgaris
Ohta, H.; Sawabu, N.; Kawakami, H.; Watanabe, H.; Ozaki, K.; Toya, D.; Hattori, N.
Characterization of g-glutamyltranspeptidase from human hepatocellular carcinoma, compared with enzymes from normal liver and cirrhotic liver
Clin. Chim. Acta
214
83-92
1993
Homo sapiens
Brouillet, A.; Darbouy, M.; Okamoto, T.; Chobert, M.N.; Lahuna, O.; Garlatti, M.; Goodspeed, D.; Laperche, Y.
Functional characterization of the rat g-glutamyl transpeptidase promoter that is expressed and regulated in the liver and hepatoma cells
J. Biol. Chem.
269
14878-14884
1994
Rattus norvegicus
Roux, F.; Durieu-Trautmann, O.; Chaverot, N.; Claire, M.; Mailly, P.; Bourre, J.M.; Strosberg, A.D.; Couraud, P.O.
Regulation of gamma-glutamyl transpeptidase and alkaline phosphatase activities in immortalized rat brain microvessel endothelial cells
J. Cell. Physiol.
159
101-113
1994
Rattus norvegicus
Krishna, R.G.; Chin, C.C.Q.; Weldon, P.J.; Wold, F.
Characterization of gamma-glutamyl transpeptidase from the Rathke's gland secretions of Kemp's ridley sea turtles (Lepidochelys kempi)
Comp. Biochem. Physiol. B
111
257-264
1995
Lepidochelys kempii
Ingbar, D.H.; Hepler, K.; Dowin, R.; Jacobsen, E.; Dunitz, J.M.; Nici, L.; Jamieson, J.D.
gamma-Glutamyl transpeptidase is a polarized alveolar epithelial membrane protein
Am. J. Physiol.
269
L261-L271
1995
Rattus norvegicus
Ikeda, Y.; Fujii, J.; Taniguchi, N.; Meister, A.
Expression of an active glycosylated human gamma-glutamyl transpeptidase mutant that lacks a membrane anchor domain
Proc. Natl. Acad. Sci. USA
92
126-130
1995
Homo sapiens
Hussein, A.S.; Walter, R.D.
Purification and characterization of gamma-glutamyl transpeptidase from Ascaris suum
Mol. Biochem. Parasitol.
77
41-47
1996
Ascaris suum
Ikeda, Y.; Fujii, J.; Taniguchi, N.
Effects of substitutions of the conserved histidine residues in human gamma-glutamyl transpeptidase
J. Biochem.
119
1166-1170
1996
Homo sapiens
Dvorakova, L.; Krusek, J.; Stastny, F.; Lisy, V.
Relationship between kinetic properties of gamma-glutamyl transpeptidase and the structure of its saccharide moiety
Biochim. Biophys. Acta
1292
163-167
1996
Rattus norvegicus
Hwang, S.Y.; Ryang, J.H.; Lim, W.J.; Yoo, I.D.; Oishi, K.
Purification and properties of gamma-glutamyl transpeptidase from Bacillus sp. KUN-17
J. Microbiol. Biotechnol.
6
238-244
1996
Bacillus sp. (in: Bacteria), Bacillus sp. (in: Bacteria) KUN-17
-
Keren, R.; Stark, A.A.
gamma-Glutamyl transpeptidase-dependent mutagenicity and cytotoxicity of gamma-glutamyl derivatives: a model for biochemical targeting of chemotherapeutic agents
Environ. Mol. Mutagen.
32
377-386
1998
Rattus norvegicus
Martin, M.N.; Slovin, J.P.
Purified gamma-glutamyl transpeptidases from tomato exhibit high affinity for glutathione and glutathione S-conjugates
Plant Physiol.
122
1417-1426
2000
Solanum lycopersicum
Chu, L.; Xu, X.; Dong, Z.; Cappelli, D.; Ebersole, J.L.
Role for recombinant gamma-glutamyltransferase from Treponema denticola in glutathione metabolism
Infect. Immun.
71
335-342
2003
Treponema denticola
Cornwell, P.D.; Watkins, J.B.
Changes in the kinetic parameters of hepatic gamma-glutamyltransferase from streptozotocin-induced diabetic rats
Biochim. Biophys. Acta
1545
184-191
2001
Rattus norvegicus
Mehdi, K.; Thierie, J.; Penninckx, M.J.
gamma-Glutamyl transpeptidase in the yeast Saccharomyces cerevisiae and its role in the vacuolar transport and metabolism of glutathione
Biochem. J.
359
631-637
2001
Saccharomyces cerevisiae
Castonguay, R.; Lherbet, C.; Keillor, J.W.
Mapping of the active site of rat kidney gamma-glutamyl transpeptidase using activated esters and their amide derivatives
Bioorg. Med. Chem.
10
4185-4191
2002
Rattus norvegicus
Storozhenko, S.; Belles-Boix, E.; Babiychuk, E.; Herouart, D.; Davey, M.W.; Slooten, L.; Van Montagu, M.; Inze, D.; Kushnir, S.
gamma-Glutamyl transpeptidase in transgenic tobacco plants. Cellular localization, processing, and biochemical properties
Plant Physiol.
128
1109-1119
2002
Arabidopsis thaliana, Arabidopsis thaliana (O65652), Arabidopsis thaliana (Q39078), Arabidopsis thaliana (Q9M0G0), Homo sapiens (P19440), Mus musculus (Q60928)
Suzuki, H.; Izuka, S.; Minami, H.; Miyakawa, N.; Ishihara, S.; Kumagai, H.
Use of bacterial gamma-glutamyltranspeptidase for enzymatic synthesis of gamma-D-glutamyl compounds
Appl. Environ. Microbiol.
69
6399-6404
2003
Escherichia coli
Suzuki, H.; Miwa, C.; Ishihara, S.; Kumagai, H.
A single amino acid substitution converts gamma-glutamyltranspeptidase to a class IV cephalosporin acylase (glutaryl-7-aminocephalosporanic acid acylase)
Appl. Environ. Microbiol.
70
6324-6328
2004
Escherichia coli
Castonguay, R.; Lherbet, C.; Keillor, J.W.
Kinetic studies of rat kidney gamma-glutamyltranspeptidase deacylation reveal a general base-catalyzed mechanism
Biochemistry
42
11504-11513
2003
Rattus norvegicus
Lherbet, C.; Gravel, C.; Keillor, J.W.
Synthesis of S-alkyl L-homocysteine analogues of glutathione and their kinetic studies with gamma-glutamyl transpeptidase
Bioorg. Med. Chem. Lett.
14
3451-3455
2004
Rattus norvegicus
Park, H.J.; Moon, J.S.; Kim, H.G.; Kim, I.H.; Kim, K.; Park, E.H.; Lim, C.J.
Characterization of a second gene encoding gamma-glutamyl transpeptidase from Schizosaccharomyces pombe
Can. J. Microbiol.
51
269-275
2005
Schizosaccharomyces pombe (O14194), Schizosaccharomyces pombe
Minami, H.; Suzuki, H.; Kumagai, H.
Salt-tolerant gamma-glutamyltranspeptidase from Bacillus subtilis 168 with glutaminase activity
Enzyme Microb. Technol.
32
431-438
2003
Bacillus subtilis, Bacillus subtilis 168
-
Minami, H.; Suzuki, H.; Kumagai, H.
A mutant Bacillus subtilis gamma-glutamyltranspeptidase specialized in hydrolysis activity
FEMS Microbiol. Lett.
224
169-173
2003
Bacillus subtilis
Sener, A.; Yardimci, T.
Activity determination, kinetic analyses and isoenzyme identification of gamma glutamyltransferase in human neutrophils
J. Biochem. Mol. Biol.
38
343-349
2005
Homo sapiens
Keillor, J.W.; Menard, A.; Castonguay, R.; Lherbet, C.; Rivard, C.
Pre-steady-state kinetic studies of rat kidney gamma-glutamyl transpeptidase confirm its ping-pong mechanism
J. Phys. Org. Chem.
17
529-536
2004
Rattus norvegicus
-
Kimura, K.; Tran, L.S.; Uchida, I.; Itoh, Y.
Characterization of Bacillus subtilis gamma-glutamyltransferase and its involvement in the degradation of capsule poly-gamma-glutamate
Microbiology
150
4115-4123
2004
Bacillus subtilis (Q83XQ6), Bacillus subtilis, Bacillus subtilis NAFM5 (Q83XQ6), Bacillus subtilis NAFM5
Lherbet, C.; Keillor, J.W.
Probing the stereochemistry of the active site of gamma-glutamyl transpeptidase using sulfur derivatives of L-glutamic acid
Org. Biomol. Chem.
2
238-245
2004
Rattus norvegicus
Shaw, M.L.; Pither-Joyce, M.D.; McCallum, J.A.
Purification and cloning of a gamma-glutamyl transpeptidase from onion (Allium cepa)
Phytochemistry
66
515-522
2005
Allium cepa
Gong, M.; Ho, B.
Prominent role of gamma-glutamyl-transpeptidase in the growth of Helicobacter pylori
World J. Gastroenterol.
10
2994-2996
2004
Helicobacter pylori, Helicobacter pylori NCTC 11637
Shaw, M.; Pither-Joyce, M.; McManus, M.; McCallum, J.
Purification, characterization and cloning of onion gamma-glutamyl transpeptidase
Acta Hortic.
688
139-141
2005
Allium cepa
-
Corti, A.; Paolicchi, A.; Franzini, M.; Dominici, S.; Casini, A.F.; Pompella, A.
The S-thiolating activity of membrane gamma-glutamyltransferase: formation of cysteinyl-glycine mixed disulfides with cellular proteins and in the cell microenvironment
Antioxid. Redox Signal.
7
911-918
2005
Homo sapiens
Lin, L.L.; Chou, P.R.; Hua, Y.W.; Hsu, W.H.
Overexpression, one-step purification, and biochemical characterization of a recombinant gamma-glutamyltranspeptidase from Bacillus licheniformis
Appl. Microbiol. Biotechnol.
73
103-112
2006
Bacillus licheniformis (Q65KZ6), Bacillus licheniformis
Iciek, M.; Chwatko, G.; Rokita, H.; Bald, E.; Wlodek, L.
The effects of modulation of gamma-glutamyl transpeptidase activity in HepG2 cells on thiol homeostasis and caspase-3-activity
Biochim. Biophys. Acta
1773
201-208
2007
Homo sapiens
Nakano, Y.; Okawa, S.; Yamauchi, T.; Koizumi, Y.; Sekiya, J.
Purification and properties of soluble and bound gamma-glutamyltransferases from radish cotyledon
Biosci. Biotechnol. Biochem.
70
369-376
2006
Raphanus sativus
Takahashi, H.; Watanabe, H.
A gonococcal homologue of meningococcal gamma-glutamyl transpeptidase gene is a new type of bacterial pseudogene that is transcriptionally active but phenotypically silent
BMC Microbiol.
5
56-56
2005
Neisseria gonorrhoeae
Lorenc-Koci, E.; Sokolowska, M.; Kwiecien, I.; Wlodek, L.
Treatment with 1,2,3,4-tetrahydroisoquinolone affects the levels of nitric oxide, S-nitrosothiols, glutathione and the enzymatic activity of gamma-glutamyl transpeptidase in the dopaminergic structures of rat brain
Brain Res.
1049
133-146
2005
Rattus norvegicus
Mares, V.; Malik, R.; Lisa, V.; Sedo, A.
Up-regulation of gamma-glutamyl transpeptidase (GGT) activity in growth perturbed C6 astrocytes
Brain Res. Mol. Brain Res.
136
75-80
2005
Rattus norvegicus
Gupta, S.; Srivastava, A.K.; Banu, N.
gamma-Glutamyl transpeptidase activity in adult Setaria cervi (filarial worms)
Helminthologia
42
57-61
2005
Setaria cervi
-
Boanca, G.; Sand, A.; Barycki, J.J.
Uncoupling the enzymatic and autoprocessing activities of Helicobacter pylori gamma-glutamyltranspeptidase
J. Biol. Chem.
281
19029-19037
2006
Helicobacter pylori
Okada, T.; Suzuki, H.; Wada, K.; Kumagai, H.; Fukuyama, K.
Crystal structure of the gamma-glutamyltranspeptidase precursor protein from Escherichia coli. Structural changes upon autocatalytic processing and implications for the maturation mechanism
J. Biol. Chem.
282
2433-2439
2007
Escherichia coli (P18956), Escherichia coli
Wu, Q.; Xu, H.; Zhang, L.; Yao, J.; Ouyang, P.
Production, purification and properties of gamma-glutamyltranspeptidase from a newly isolated Bacillus subtilis NX-2
J. Mol. Catal. B
43
113-117
2006
Bacillus subtilis, Bacillus subtilis NX-2
-
Kinlough, C.L.; Poland, P.A.; Bruns, J.B.; Hughey, R.P.
gamma-Glutamyltranspeptidase: disulfide bridges, propeptide cleavage, and activation in the endoplasmic reticulum
Methods Enzymol.
401
426-449
2005
Rattus norvegicus
Keillor, J.W.; Castonguay, R.; Lherbet, C.
gamma-Glutamyl transpeptidase substrate specificity and catalytic mechanism
Methods Enzymol.
401
449-467
2005
Homo sapiens
Kaiser, M.; Mares, V.; Stastny, F.; Bubenikova-Valesova, V.; Lisa, V.; Suchomel, P.; Balcar, V.J.
The influence of interleukin-1beta on gamma-glutamyl transpepidase activity in rat hippocampus
Physiol. Res.
55
461-465
2006
Rattus norvegicus
Okada, T.; Suzuki, H.; Wada, K.; Kumagai, H.; Fukuyama, K.
Crystal structures of gamma-glutamyltranspeptidase from Escherichia coli, a key enzyme in glutathione metabolism, and its reaction intermediate
Proc. Natl. Acad. Sci. USA
103
6471-6476
2006
Escherichia coli (P18956), Escherichia coli
Moallic, C.; Dabonne, S.; Colas, B.; Sine, J.P.
Identification and characterization of a gamma-glutamyl transpeptidase from a thermo-alcalophile strain of Bacillus pumilus
Protein J.
25
391-397
2006
Bacillus pumilus, Bacillus pumilus A8
Yao, Y.F.; Weng, Y.M.; Hu, H.Y.; Ku, K.L.; Lin, L.L.
Expression optimization and biochemical characterization of a recombinant gamma-glutamyltranspeptidase from Escherichia coli novablue
Protein J.
25
431-441
2006
Escherichia coli, Escherichia coli Novablue
Khedmat, H.; Fallahian, F.; Abolghasemi, H.; Hajibeigi, B.; Attarchi, Z.; Alaeddini, F.; Holisaz, M.T.; Pourali, M.; Sharifi, S.; Zarei, N.
Serum gamma-glutamyltransferase, alanine aminotransferase, and aspartate aminotransferase activity in Iranian healthy blood donor men
World J. Gastroenterol.
13
889-894
2007
Homo sapiens
do Amaral, R.A.; Malbergier, A.
Effectiveness of the CAGE questionnaire, gamma-glutamyltransferase and mean corpuscular volume of red blood cells as markers for alcohol-related problems in the workplace
Addict. Behav.
33
772-781
2008
Homo sapiens
Franzini, M.; Bramanti, E.; Ottaviano, V.; Ghiri, E.; Scatena, F.; Barsacchi, R.; Pompella, A.; Donato, L.; Emdin, M.; Paolicchi, A.
A high performance gel filtration chromatography method for gamma-glutamyltransferase fraction analysis
Anal. Biochem.
374
1-6
2008
Homo sapiens
Laskaj, R.; Dodig, S.; Slavica, D.; Cepelak, I.; Kuzman, I.
gamma-Glutamyltransferase activity and total antioxidant status in serum and platelets of patients with community-acquired pneumonia
Arch. Med. Res.
38
424-431
2007
Homo sapiens
Fraser, A.; Harris, R.; Sattar, N.; Ebrahim, S.; Smith, G.D.; Lawlor, D.A.
gamma-Glutamyltransferase is associated with incident vascular events independently of alcohol intake: analysis of the British womens heart and health study and meta-analysis
Arterioscler. Thromb. Vasc. Biol.
27
2729-2735
2007
Homo sapiens
Strasak, A.M.; Kelleher, C.C.; Klenk, J.; Brant, L.J.; Ruttmann, E.; Rapp, K.; Concin, H.; Diem, G.; Pfeiffer, K.P.; Ulmer, H.; Ulmer, H.
Longitudinal change in serum gamma-glutamyltransferase and cardiovascular disease mortality: a prospective population-based study in 76,113 Austrian adults
Arterioscler. Thromb. Vasc. Biol.
28
1857-1865
2008
Homo sapiens
Giral, P.; Jacob, N.; Dourmap, C.; Hansel, B.; Carrie, A.; Bruckert, E.; Girerd, X.; Chapman, M.J.
Elevated gamma-glutamyltransferase activity and perturbed thiol profile are associated with features of metabolic syndrome
Arterioscler. Thromb. Vasc. Biol.
28
587-593
2008
Homo sapiens
Shankar, A.; Li, J.; Klein, B.E.; Javier Nieto, F.; Klein, R.
Serum gamma-glutamyltransferase level and peripheral arterial disease
Atherosclerosis
199
102-109
2008
Homo sapiens
Caliskan, M.; Erdogan, D.; Gullu, H.; Muderrisoglu, H.
Higher serum gamma-glutamyltransferase levels are independently associated with impaired coronary microvascular function in patients with dilated cardiomyopathy
Atherosclerosis
201
163-167
2008
Homo sapiens
Franzini, M.; Corti, A.; Martinelli, B.; Del Corso, A.; Emdin, M.; Parenti, G.F.; Glauber, M.; Pompella, A.; Paolicchi, A.
gamma-Glutamyltransferase activity in human atherosclerotic plaques - biochemical similarities with the circulating enzyme
Atherosclerosis
202
119-127
2008
Homo sapiens
Han, L.; Hiratake, J.; Kamiyama, A.; Sakata, K.
Design, synthesis, and evaluation of gamma-phosphono diester analogues of glutamate as highly potent inhibitors and active site probes of gamma-glutamyl transpeptidase
Biochemistry
46
1432-1447
2007
Escherichia coli, Homo sapiens
Strasak, A.M.; Rapp, K.; Brant, L.J.; Hilbe, W.; Gregory, M.; Oberaigner, W.; Ruttmann, E.; Concin, H.; Diem, G.; Pfeiffer, K.P.; Ulmer, H.; Ulmer, H.
Association of gamma-glutamyltransferase and risk of cancer incidence in men: a prospective study
Cancer Res.
68
3970-3977
2008
Homo sapiens
Shankar, A.; Li, J.
Association between serum gamma-glutamyltransferase level and prehypertension among US adults
Circ. J.
71
1567-1572
2007
Homo sapiens
Song, S.H.; Kwak, I.S.; Kim, Y.J.; Kim, S.J.; Lee, S.B.; Lee, D.W.; Lee, B.E.
Can gamma-glutamyltransferase be an additional marker of arterial stiffness?
Circ. J.
71
1715-1720
2007
Homo sapiens
Lim, J.S.; Lee, D.H.; Park, J.Y.; Jin, S.H.; Jacobs, D.R.
A strong interaction between serum gamma-glutamyltransferase and obesity on the risk of prevalent type 2 diabetes: results from the third national health and nutrition examination survey
Clin. Chem.
53
1092-1098
2007
Homo sapiens
Steinmetz, J.; Schiele, F.; Gueguen, R.; Ferard, G.; Henny, J.; Henny, J.
Standardization of gamma-glutamyltransferase assays by intermethod calibration. Effect on determining common reference limits
Clin. Chem. Lab. Med.
45
1373-1380
2007
Homo sapiens
Salvagno, G.L.; Lippi, G.; Montagnana, M.; Brocco, G.; Guidi, G.C.
Non-homogeneous separation of triglycerides, gamma-glutamyltransferase, C-reactive protein and lactate dehydrogenase after centrifugation of lithium-heparin tubes
Clin. Chem. Lab. Med.
46
1180-1182
2008
Homo sapiens
Lippi, G.; Targher, G.; Montagnana, M.; Salvagno, G.L.; Guidi, G.C.
Relationship between gamma-glutamyltransferase, lipids and lipoprotein(a) in the general population
Clin. Chim. Acta
384
163-166
2007
Homo sapiens
Fukushima, Y.; Seo, T.; Hashimoto, N.; Higa, Y.; Ishitsu, T.; Nakagawa, K.
Glutathione-S-transferase (GST) M1 null genotype and combined GSTM1 and GSTT1 null genotypes are risk factors for increased serum gamma-glutamyltransferase in valproic acid-treated patients
Clin. Chim. Acta
389
98-102
2008
Homo sapiens
Pompella, A.; Corti, A.; Paolicchi, A.; Giommarelli, C.; Zunino, F.
gamma-Glutamyltransferase, redox regulation and cancer drug resistance
Curr. Opin. Pharmacol.
7
360-366
2007
Homo sapiens
Lee, M.Y.; Koh, S.B.; Koh, J.H.; Nam, S.M.; Shin, J.Y.; Shin, Y.G.; Kong, I.D.; Ryu, S.Y.; Lee, T.Y.; Park, J.K.; Chung, C.H.
Relationship between gamma-glutamyltransferase and metabolic syndrome in a Korean population
Diabet. Med.
25
469-475
2008
Homo sapiens
Andre, P.; Balkau, B.; Vol, S.; Charles, M.A.; Eschwege, E.; Eschwege, E.
gamma-Glutamyltransferase activity and development of the metabolic syndrome (International Diabetes Federation Definition) in middle-aged men and women: Data from the Epidemiological Study on the Insulin Resistance Syndrome (DESIR) cohort
Diabetes Care
30
2355-2361
2007
Homo sapiens
Botton, J.; Heude, B.; Andre, P.; Bresson, J.L.; Ducimetiere, P.; Charles, M.A.; Charles, M.A.
Relationship between gamma-glutamyltransferase and fat mass in a general population of 8-17 years old children. The FLVS II study
Diabetes Metab.
33
354-359
2007
Homo sapiens
Kang, Y.H.; Min, H.K.; Son, S.M.; Kim, I.J.; Kim, Y.K.
The association of serum gamma glutamyltransferase with components of the metabolic syndrome in the Korean adults
Diabetes Res. Clin. Pract.
77
306-313
2007
Homo sapiens
Iwasaki, T.; Yoneda, M.; Kawasaki, S.; Fujita, K.; Nakajima, A.; Terauchi, Y.
Hepatic fat content-independent association of the serum level of gamma-glutamyltransferase with visceral adiposity, but not subcutaneous adiposity
Diabetes Res. Clin. Pract.
79(1)
e13-e14
2008
Homo sapiens
Hashimoto, Y.; Futamura, A.
Relationship between response of gamma-glutamyltransferase to alcohol consumption and levels of fasting plasma glucose
Diabetes Res. Clin. Pract.
80
469-472
2008
Homo sapiens
Lee, D.H.; Steffes, M.W.; Jacobs, D.R.
Can persistent organic pollutants explain the association between serum gamma-glutamyltransferase and type 2 diabetes?
Diabetologia
51
402-407
2008
Homo sapiens
Sattar, N.; Wannamethee, S.G.; Forouhi, N.G.
Novel biochemical risk factors for type 2 diabetes: pathogenic insights or prediction possibilities?
Diabetologia
51
926-940
2008
Homo sapiens
Rinck, D.; Frieling, H.; Freitag, A.; Hillemacher, T.; Bayerlein, K.; Kornhuber, J.; Bleich, S.
Combinations of carbohydrate-deficient transferrin, mean corpuscular erythrocyte volume, gamma-glutamyltransferase, homocysteine and folate increase the significance of biological markers in alcohol dependent patients
Drug Alcohol Depend.
89
60-65
2007
Homo sapiens
Hiramatsu, K.; Asaba, Y.; Takeshita, S.; Nimura, Y.; Tatsumi, S.; Katagiri, N.; Niida, S.; Nakajima, T.; Tanaka, S.; Ito, M.; Karsenty, G.; Ikeda, K.
Overexpression of gamma-glutamyltransferase in transgenic mice accelerates bone resorption and causes osteoporosis
Endocrinology
148
2708-2715
2007
Mus musculus
Giommarelli, C.; Corti, A.; Supino, R.; Favini, E.; Paolicchi, A.; Pompella, A.; Zunino, F.
Cellular response to oxidative stress and ascorbic acid in melanoma cells overexpressing gamma-glutamyltransferase
Eur. J. Cancer
44
750-759
2008
Homo sapiens
Lee, D.H.; Buijsse, B.; Steffen, L.; Holtzman, J.; Luepker, R.; Jacobs, D.R.
Association between serum gamma-glutamyltransferase and cardiovascular mortality varies by age: the Minnesota Heart Survey
Eur. J. Cardiovasc. Prev. Rehabil.
16
16-20
2008
Homo sapiens
Bidel, S.; Silventoinen, K.; Hu, G.; Lee, D.H.; Kaprio, J.; Tuomilehto, J.
Coffee consumption, serum gamma-glutamyltransferase and risk of type II diabetes
Eur. J. Clin. Nutr.
62
178-185
2008
Homo sapiens
Langford, M.P.; Redens, T.B.; Harris, N.R.; Lee, S.; Jain, S.K.; Reddy, S.; McVie, R.
Plasma levels of cell-free apoptotic DNA ladders and gamma-glutamyltranspeptidase (GGT) in diabetic children
Exp. Biol. Med.
232
1160-1169
2007
Homo sapiens
Grzam, A.; Martin, M.N.; Hell, R.; Meyer, A.J.
gamma-Glutamyl transpeptidase GGT4 initiates vacuolar degradation of glutathione S-conjugates in Arabidopsis
FEBS Lett.
581
3131-3138
2007
Arabidopsis thaliana (Q9M0G0), Arabidopsis thaliana
Pandur, S.; Pankiv, S.; Johannessen, M.; Moens, U.; Huseby, N.E.
Gamma-glutamyltransferase is upregulated after oxidative stress through the Ras signal transduction pathway in rat colon carcinoma cells
Free Radic. Res.
41
1376-1384
2007
Rattus norvegicus
Kwiecien, I.; Rokita, H.; Lorenc-Koci, E.; Sokolowska, M.; Wlodek, L.
The effect of modulation of gamma-glutamyl transpeptidase and nitric oxide synthase activity on GSH homeostasis in HepG2 cells
Fundam. Clin. Pharmacol.
21
95-103
2007
Homo sapiens
Schmees, C.; Prinz, C.; Treptau, T.; Rad, R.; Hengst, L.; Voland, P.; Bauer, S.; Brenner, L.; Schmid, R.M.; Gerhard, M.
Inhibition of T-cell proliferation by Helicobacter pylori gamma-glutamyl transpeptidase
Gastroenterology
132
1820-1833
2007
Helicobacter pylori
Takigawa, T.; Hibino, Y.; Kimura, S.; Yamauchi, H.; Wang, B.; Wang, D.; Ogino, K.
Association between serum gamma-glutamyltransferase and oxidative stress related factors
Hepatogastroenterology
55
50-53
2008
Homo sapiens
Fraser, A.; Ebrahim, S.; Smith, G.D.; Lawlor, D.A.
A comparison of associations of alanine aminotransferase and gamma-glutamyltransferase with fasting glucose, fasting insulin, and glycated hemoglobin in women with and without diabetes
Hepatology
46
158-165
2007
Homo sapiens
Hu, G.; Tuomilehto, J.; Pukkala, E.; Hakulinen, T.; Antikainen, R.; Vartiainen, E.; Jousilahti, P.
Joint effects of coffee consumption and serum gamma-glutamyltransferase on the risk of liver cancer
Hepatology
48
129-136
2008
Homo sapiens
Heisterkamp, N.; Groffen, J.; Warburton, D.; Sneddon, T.P.
The human gamma-glutamyltransferase gene family
Hum. Genet.
123
321-332
2008
Homo sapiens (P19440), Homo sapiens (P36269), Homo sapiens
Falabella, P.; Riviello, L.; Caccialupi, P.; Rossodivita, T.; Teresa Valente, M.; Luisa De Stradis, M.; Tranfaglia, A.; Varricchio, P.; Gigliotti, S.; Graziani, F.; Malva, C.; Pennacchio, F.
A gamma-glutamyl transpeptidase of Aphidius ervi venom induces apoptosis in the ovaries of host aphids
Insect Biochem. Mol. Biol.
37
453-465
2007
Aphidius ervi
Strasak, A.M.; Pfeiffer, R.M.; Klenk, J.; Hilbe, W.; Oberaigner, W.; Gregory, M.; Concin, H.; Diem, G.; Pfeiffer, K.P.; Ruttmann, E.; Ulmer, H.; Ulmer, H.
Prospective study of the association of gamma-glutamyltransferase with cancer incidence in women
Int. J. Cancer
123
1902-1906
2008
Homo sapiens
Emdin, M.; Passino, C.; Michelassi, C.; Donato, L.; Pompella, A.; Paolicchi, A.
Additive prognostic value of gamma-glutamyltransferase in coronary artery disease
Int. J. Cardiol.
136
80-85
2008
Homo sapiens
Yavuz, B.B.; Yavuz, B.; Halil, M.; Cankurtaran, M.; Ulger, Z.; Cankurtaran, E.S.; Aytemir, K.; Ariogul, S.
Serum elevated gamma glutamyltransferase levels may be a marker for oxidative stress in Alzheimers disease
Int. Psychogeriatr.
20
815-823
2008
Homo sapiens
Li, L.; Hu, D.; Jiang, Y.; Chen, F.; Hu, X.; Zhao, G.
Relationship between gamma-glutamyl transpeptidase activity and garlic greening, as controlled by temperature
J. Agric. Food Chem.
56
941-945
2008
Allium sativum
Corti, A.; Franzini, M.; Casini, A.F.; Paolicchi, A.; Pompella, A.
Vitamin C supply to bronchial epithelial cells linked to glutathione availability in elf--a role for secreted gamma-glutamyltransferase?
J. Cyst. Fibros.
7
174-178
2008
Homo sapiens
Bozbas, H.; Yildirir, A.; Demir, O.; Cakmak, A.; Karacaglar, E.; Yilmaz, M.; Eroglu, S.; Pirat, B.; Ozin, B.; Muderrisoglu, H.
Serum gamma-glutamyltransferase activity is increased in patients with calcific aortic valve stenosis
J. Heart Valve Dis.
17
371-375
2008
Homo sapiens
Caliskan, M.; Erdogan, D.; Gullu, H.; Ciftci, O.; Yildirim, I.; Baycan, S.; Yildirir, A.; Muderrisoglu, H.
Association between serum gamma-glutamyltransferase levels and coronary microvascular function in hypertensive patients
J. Hypertens.
25
2497-2503
2007
Homo sapiens
Bergmann, J.F.; Vrolijk, J.M.; van der Schaar, P.; Vroom, B.; van Hoek, B.; van der Sluys Veer, A.; de Vries, R.A.; Verhey, E.; Hansen, B.E.; Brouwer, J.T.; Janssen, H.L.; Schalm, S.W.; de Knegt, R.J.
gamma-Glutamyltransferase and rapid virological response as predictors of successful treatment with experimental or standard peginterferon-alpha-2b in chronic hepatitis C non-responders
Liver Int.
27
1217-1225
2007
Homo sapiens
Harasymiw, J.; Bean, P.
The early detection of alcohol consumption (EDAC) test shows better performance than gamma-glutamyltransferase (GGT) to detect heavy drinking in a large population of males and females
Med. Sci. Monit.
13
PI19-PI24
2007
Homo sapiens
Kim, J.A.; Kim, S.M.; Yoon, D.
The relationship between gamma-glutamyltransferase and adiponectin in nonalcoholic women
Metab. Clin. Exp.
56
578-582
2007
Homo sapiens
Barnes, I.H.; Bagnall, M.C.; Browning, D.D.; Thompson, S.A.; Manning, G.; Newell, D.G.
gamma-Glutamyl transpeptidase has a role in the persistent colonization of the avian gut by Campylobacter jejuni
Microb. Pathog.
43
198-207
2007
Campylobacter jejuni
Zarnowski, R.; Cooper, K.G.; Brunold, L.S.; Calaycay, J.; Woods, J.P.
Histoplasma capsulatum secreted gamma-glutamyltransferase reduces iron by generating an efficient ferric reductant
Mol. Microbiol.
70
352-368
2008
Histoplasma capsulatum
Saijo, Y.; Utsugi, M.; Yoshioka, E.; Horikawa, N.; Sato, T.; Gong, Y.; Kishi, R.
The relationship of gamma-glutamyltransferase to C-reactive protein and arterial stiffness
Nutr. Metab. Cardiovasc. Dis.
18
211-219
2008
Homo sapiens
Simao, A.N.; Dichi, J.B.; Barbosa, D.S.; Cecchini, R.; Dichi, I.
Influence of uric acid and gamma-glutamyltransferase on total antioxidant capacity and oxidative stress in patients with metabolic syndrome
Nutrition
24
675-681
2008
Homo sapiens
Trachtenberg, F.; Barregard, L.; McKinlay, S.
The influence of urinary flow rate in children on excretion of markers used for assessment of renal damage: albumin, gamma-glutamyl transpeptidase, N-acetyl-beta-D-glucosaminidase, and alpha1-microglobulin
Pediatr. Nephrol.
23
445-456
2008
Homo sapiens
Ohkama-Ohtsu, N.; Zhao, P.; Xiang, C.; Oliver, D.J.
Glutathione conjugates in the vacuole are degraded by gamma-glutamyl transpeptidase GGT3 in Arabidopsis
Plant J.
49
878-888
2007
Arabidopsis thaliana (Q9M0G0)
Martin, M.N.; Saladores, P.H.; Lambert, E.; Hudson, A.O.; Leustek, T.
Localization of members of the gamma-glutamyl transpeptidase family identifies sites of glutathione and glutathione S-conjugate hydrolysis
Plant Physiol.
144
1715-1732
2007
Arabidopsis thaliana (O65652), Arabidopsis thaliana (Q680I5), Arabidopsis thaliana (Q9CAR5), Arabidopsis thaliana (Q9M0G0), Arabidopsis thaliana
Ohkama-Ohtsu, N.; Oikawa, A.; Zhao, P.; Xiang, C.; Saito, K.; Oliver, D.J.
A gamma-glutamyl transpeptidase-independent pathway of glutathione catabolism to glutamate via 5-oxoproline in Arabidopsis
Plant Physiol.
148
1603-1613
2008
Arabidopsis thaliana, Arabidopsis thaliana (Q9LR30)
Puukka, K.; Hietala, J.; Koivisto, H.; Anttila, P.; Bloigu, R.; Niemelae, O.
Obesity and the clinical use of serum GGT activity as a marker of heavy drinking
Scand. J. Clin. Lab. Invest.
67
480-488
2007
Homo sapiens
Souza, J.F.; Longui, C.A.; Miorin, L.A.; Sens, Y.A.
gamma-Glutamyltransferase activity in chronic dialysis patients and renal transplant recipients with hepatitis C virus infection
Transplant. Proc.
40
1319-1323
2008
Homo sapiens
Kaufmann, Y.; Todorova, V.K.; Luo, S.; Klimberg, V.S.
Glutamine affects glutathione recycling enzymes in a DMBA-induced breast cancer model
Nutr. Cancer
60
518-525
2008
Rattus norvegicus (P07314)
Wannamethee, S.G.; Lennon, L.; Shaper, A.G.
The value of gamma-glutamyltransferase in cardiovascular risk prediction in men without diagnosed cardiovascular disease or diabetes
Atherosclerosis
201
168-175
2008
Homo sapiens
Angeli, V.; Tacito, A.; Paolicchi, A.; Barsacchi, R.; Franzini, M.; Baldassini, R.; Vecoli, C.; Pompella, A.; Bramanti, E.
A kinetic study of gamma-glutamyltransferase (GGT)-mediated S-nitrosoglutathione catabolism
Arch. Biochem. Biophys.
481
191-196
2009
Bos taurus
Bramanti, E.; Angeli, V.; Franzini, M.; Vecoli, C.; Baldassini, R.; Paolicchi, A.; Barsacchi, R.; Pompella, A.
Exogenous vs. endogenous gamma-glutamyltransferase activity: Implications for the specific determination of S-nitrosoglutathione in biological samples
Arch. Biochem. Biophys.
487
146-152
2009
Bos taurus
Vergauwen, B.; Dudycz, L.W.; Dansercoer, A.; Devreese, B.
A direct spectrophotometric gamma-glutamyltransferase inhibitor screening assay targeting the hydrolysis-only mode
Biochem. Biophys. Res. Commun.
380
591-596
2009
Equus caballus
Reuter, S.; Schnekenburger, M.; Cristofanon, S.; Buck, I.; Teiten, M.H.; Daubeuf, S.; Eifes, S.; Dicato, M.; Aggarwal, B.B.; Visvikis, A.; Diederich, M.
Tumor necrosis factor alpha induces gamma-glutamyltransferase expression via nuclear factor-kappaB in cooperation with Sp1
Biochem. Pharmacol.
77
397-411
2009
Homo sapiens
Castellano, I.; Merlino, A.; Rossi, M.; La Cara, F.
Biochemical and structural properties of gamma-glutamyl transpeptidase from Geobacillus thermodenitrificans: An enzyme specialized in hydrolase activity
Biochimie
92
464-474
2010
Geobacillus thermodenitrificans, Geobacillus thermodenitrificans NG80-2
Franzini, M.; Corti, A.; Fornaciari, I.; Balderi, M.; Torracca, F.; Lorenzini, E.; Baggiani, A.; Pompella, A.; Emdin, M.; Paolicchi, A.
Cultured human cells release soluble gamma-glutamyltransferase complexes corresponding to the plasma b-GGT
Biomarkers
14
486-492
2009
Homo sapiens
Grillo, M.P.; Hua, F.; March, K.L.; Benet, L.Z.; Knutson, C.G.; Ware, J.A.
Gamma-glutamyltranspeptidase-mediated degradation of diclofenac-S-acyl-glutathione in vitro and in vivo in rat
Chem. Res. Toxicol.
21
1933-1938
2008
Rattus norvegicus
Demircan, S.; Yazici, M.; Durna, K.; Kilicaslan, F.; Demir, S.; Pinar, M.; Gulel, O.
The importance of gamma-glutamyltransferase activity in patients with coronary artery disease
Clin. Cardiol.
32
220-225
2009
Homo sapiens
Lin, L.L.; Yang, L.Y.; Hu, H.Y.; Lo, H.F.
Influence of N-terminal truncations on the functional expression of Bacillus licheniformis gamma-glutamyltranspeptidase in recombinant Escherichia coli
Curr. Microbiol.
57
603-608
2008
Bacillus licheniformis
Lyu, R.C.; Hu, H.Y.; Kuo, L.Y.; Lo, H.F.; Ong, P.L.; Chang, H.P.; Lin, L.L.
Role of the conserved Thr399 and Thr417 residues of Bacillus licheniformis gamma-Glutamyltranspeptidase as evaluated by mutational analysis
Curr. Microbiol.
59
101-106
2009
Bacillus licheniformis
Becerra-Torres, S.L.; Rodriguez-Vazquez, M.L.; Medina-Ramirez, I.E.; Jaramillo-Juarez, F.
Potassium dichromate-induced changes on urinary-specific activities of gamma-glutamyl transpeptidase and alanine aminopeptidase enzymes
Drug Chem. Toxicol.
32
21-25
2009
Rattus norvegicus
Adamis, P.D.; Mannarino, S.C.; Eleutherio, E.C.
Glutathione and gamma-glutamyl transferases are involved in the formation of cadmium-glutathione complex
FEBS Lett.
583
1489-1492
2009
Saccharomyces cerevisiae
Giommarelli, C.; Corti, A.; Supino, R.; Favini, E.; Paolicchi, A.; Pompella, A.; Zunino, F.
Gamma-glutamyltransferase-dependent resistance to arsenic trioxide in melanoma cells and cellular sensitization by ascorbic acid
Free Radic. Biol. Med.
46
1516-1526
2009
Homo sapiens
Claessen, H.; Brenner, H.; Drath, C.; Arndt, V.
Gamma-glutamyltransferase and disability pension: a cohort study of construction workers in Germany
Hepatology
51
482-490
2010
Homo sapiens
Hsu, W.H.; Ong, P.L.; Chen, S.C.; Lin, L.L.
Contribution of Ser463 residue to the enzymatic and autoprocessing activities of Escherichia coli gamma-glutamyltranspeptidase
Indian J. Biochem. Biophys.
46
281-288
2009
Escherichia coli (P18956), Escherichia coli
Lo, H.F.; Chou, W.M.; Chen, P.J.; Lin, L.L.
Influence of signal-peptide truncations on the functional expression of Escherichia coli gamma -glutamyltranspeptidase
J. Basic Microbiol.
48
260-268
2008
Escherichia coli (P18956), Escherichia coli
King, J.B.; West, M.B.; Cook, P.F.; Hanigan, M.H.
A novel, species-specific class of uncompetitive inhibitors of gamma-glutamyl transpeptidase
J. Biol. Chem.
284
9059-9065
2009
Homo sapiens
Wada, K.; Hiratake, J.; Irie, M.; Okada, T.; Yamada, C.; Kumagai, H.; Suzuki, H.; Fukuyama, K.
Crystal structures of Escherichia coli gamma-glutamyltranspeptidase in complex with azaserine and acivicin: novel mechanistic implication for inhibition by glutamine antagonists
J. Mol. Biol.
380
361-372
2008
Escherichia coli (P18956), Escherichia coli
Corti, A.; Duarte, T.L.; Giommarelli, C.; De Tata, V.; Paolicchi, A.; Jones, G.D.; Pompella, A.
Membrane gamma-glutamyl transferase activity promotes iron-dependent oxidative DNA damage in melanoma cells
Mutat. Res.
669
112-121
2009
Homo sapiens
Ferretti, M.; Destro, T.; Tosatto, S.C.; La Rocca, N.; Rascio, N.; Masi, A.
Gamma-glutamyl transferase in the cell wall participates in extracellular glutathione salvage from the root apoplast
New Phytol.
181
115-126
2009
Hordeum vulgare
Wainford, R.D.; Weaver, R.J.; Stewart, K.N.; Brown, P.; Hawksworth, G.M.
Cisplatin nephrotoxicity is mediated by gamma glutamyltranspeptidase, not via a C-S lyase governed biotransformation pathway
Toxicology
249
184-193
2008
Mus musculus, Rattus norvegicus
Tiwary, E.; Gupta, R.
Improved catalytic efficiency of a monomeric gamma-glutamyl transpeptidase from Bacillus licheniformis in presence of subtilisin
Biotechnol. Lett.
32
1137-1141
2010
Bacillus licheniformis, Bacillus licheniformis ER-15
Wickham, S.; West, M.; Cook, P.; Hanigan, M.
Gamma-glutamyl compounds: Substrate specificity of gamma-glutamyl transpeptidase enzymes
Anal. Biochem.
414
208-214
2011
Homo sapiens, Homo sapiens (P19440)
Chang, H.P.; Liang, W.C.; Lyu, R.C.; Chi, M.C.; Wang, T.F.; Su, K.L.; Hung, H.C.; Lin, L.L.
Effects of C-terminal truncation on autocatalytic processing of Bacillus licheniformis gamma-glutamyl transpeptidase
Biochemistry
75
919-929
2010
Bacillus licheniformis (Q65KZ6), Bacillus licheniformis, Bacillus licheniformis ATCC 14580 (Q65KZ6)
Zhang, F.; Zheng, Q.Z.; Jiao, Q.C.; Liu, J.Z.; Zhao, G.H.
Synthesis of theanine from glutamic acid gamma-methyl ester and ethylamine catalyzed by Escherichia coli having gamma-glutamyltranspeptidase activity
Biotechnol. Lett.
32
1147-1150
2010
Escherichia coli
Wada, K.; Irie, M.; Suzuki, H.; Fukuyama, K.
Crystal structure of the halotolerant gamma-glutamyltranspeptidase from Bacillus subtilis in complex with glutamate reveals a unique architecture of the solvent-exposed catalytic pocket
FEBS J.
277
1000-1009
2010
Bacillus subtilis (P54422), Bacillus subtilis, Bacillus subtilis 168 (P54422)
West, M.B.; Wickham, S.; Quinalty, L.M.; Pavlovicz, R.E.; Li, C.; Hanigan, M.H.
Autocatalytic cleavage of human gamma-glutamyl transpeptidase is highly dependent on N-glycosylation at asparagine 95
J. Biol. Chem.
286
28876-28888
2011
Homo sapiens (P19440), Homo sapiens
Destro, T.; Prasad, D.; Martignago, D.; Bernet, I.L.; Trentin, A.R.; Renu, I.K.; Ferretti, M.; Masi, A.
Compensatory expression and substrate inducibility of gamma-glutamyl transferase GGT2 isoform in Arabidopsis thaliana
J. Exp. Bot.
62
805-814
2011
Arabidopsis thaliana, Arabidopsis thaliana (Q680I5), Arabidopsis thaliana (Q8VYW6), Arabidopsis thaliana (Q9M0G0)
Kim, K.M.; Lee, S.G.; Kim, J.M.; Kim, D.S.; Song, J.Y.; Kang, H.L.; Lee, W.K.; Cho, M.J.; Rhee, K.H.; Youn, H.S.; Baik, S.C.
Helicobacter pylori gamma-glutamyltranspeptidase induces cell cycle arrest at the G1-S phase transition
J. Microbiol.
48
372-377
2010
Helicobacter pylori, Helicobacter pylori 51
Kean, E.A.; Hare, E.R.
gamma-Glutamyl transpeptidase of the ackee plant
Phytochemistry
19
199-203
1980
Blighia sapida
-
Rajput, R.; Verma, V.V.; Chaudhary, V.; Gupta, R.
A hydrolytic gamma-glutamyl transpeptidase from thermo-acidophilic archaeon Picrophilus torridus: binding pocket mutagenesis and transpeptidation
Extremophiles
17
29-41
2012
Picrophilus torridus (Q6KZT2), Picrophilus torridus DSM 9790 (Q6KZT2)
Kushwaha, N.; Srivastava, S.
Gamma-glutamyl transpeptidase from two plant growth promoting rhizosphere fluorescent pseudomonads
Antonie van Leeuwenhoek
105
45-56
2014
Pseudomonas fluorescens (Q4KIM5), Pseudomonas fluorescens, Pseudomonas fluorescens Pf-5 (Q4KIM5)
Agblor, A.A.; Josephy, P.D.
Donor substrate specificity of bovine kidney gamma-glutamyltransferase
Chem. Biol. Interact.
203
480-485
2013
Bos taurus
Balakrishna, S.; Prabhune, A.
Gamma-glutamyl transferases: A structural, mechanistic and physiological perspective
Front. Biol.
9
51-65
2014
Homo sapiens (P19440), Bacillus subtilis (P54422), Bacillus subtilis 168 (P54422)
-
Hanigan, M.H.; Gillies, E.M.; Wickham, S.; Wakeham, N.; Wirsig-Wiechmann, C.R.
Immunolabeling of gamma-glutamyl transferase 5 in normal human tissues reveals that expression and localization differ from gamma-glutamyl transferase 1
Histochem. Cell Biol.
143
505-515
2015
Homo sapiens
Ki, M.R.; Yun, N.R.; Hwang, S.Y.
Glutamine-induced production and secretion of Helicobacter pylori gamma-glutamyltranspeptidase at low pH and its putative role in glutathione transport
J. Microbiol. Biotechnol.
23
467-472
2013
Helicobacter pylori, Helicobacter pylori ATCC 49503
Fornaciari, I.; Fierabracci, V.; Corti, A.; Aziz Elawadi, H.; Lorenzini, E.; Emdin, M.; Paolicchi, A.; Franzini, M.
Gamma-glutamyltransferase fractions in human plasma and bile: characteristic and biogenesis
PLoS ONE
9
e88532
2014
Homo sapiens
Balakrishna, S.; Prabhune, A.
Effect of pH on the hydrolytic kinetics of gamma-glutamyl transferase from Bacillus subtilis
ScientificWorldJournal
2014
216270
2014
Bacillus subtilis
Wisnewski, A.V.; Liu, J.; Nassar, A.F.
In vitro cleavage of diisocyanate-glutathione conjugates by human gamma-glutamyl transpeptidase-1
Xenobiotica
46
726-732
2016
Homo sapiens
Kamiyama, A.; Nakajima, M.; Han, L.; Wada, K.; Mizutani, M.; Tabuchi, Y.; Kojima-Yuasa, A.; Matsui-Yuasa, I.; Suzuki, H.; Fukuyama, K.; Watanabe, B.; Hiratake, J.
Phosphonate-based irreversible inhibitors of human gamma-glutamyl transpeptidase (GGT). GGsTop is a non-toxic and highly selective inhibitor with critical electrostatic interaction with an active-site residue Lys562 for enhanced inhibitory activity
Bioorg. Med. Chem.
24
5340-5352
2016
Escherichia coli (P18956), Escherichia coli, Homo sapiens (P19440), Homo sapiens
Bindal, S.; Sharma, S.; Singh, T.P.; Gupta, R.
Evolving transpeptidase and hydrolytic variants of gamma-glutamyl transpeptidase from Bacillus licheniformis by targeted mutations of conserved residue Arg109 and their biotechnological relevance
J. Biotechnol.
249
82-90
2017
Bacillus licheniformis (A9YTT0), Bacillus licheniformis, Bacillus licheniformis ER15 (A9YTT0)
Spitzmller, Z.; Gonda, S.; Kiss-Szikszai, A.; Vasas, G.; Pocsi, I.; Emri, T.
Characterization of extracellular gamma-glutamyl transpeptidase from Aspergillus nidulans
Mycoscience
57
400-403
2016
Aspergillus nidulans
-
Nishihara, T.; Yoshihara, H.; Nonaka, H.; Takakusagi, Y.; Hyodo, F.; Ichikawa, K.; Can, E.; Bastiaansen, J.; Takado, Y.; Comment, A.; Sando, S.
Direct monitoring of gamma-glutamyl transpeptidase activity in vivo using a hyperpolarized 13C-labeled molecular probe
Angew. Chem. Int. Ed. Engl.
55
10626-10629
2016
Rattus norvegicus
Chi, M.; Lo, H.; Lin, M.; Chen, Y.; Lin, L.; Wang, T.
Application of Bacillus licheniformis gamma-glutamyltranspeptidase to the biocatalytic synthesis of gamma-glutamyl-phenylalanine
Biocatal. Agricult. Biotechnol.
10
278-284
2017
Bacillus licheniformis (A0A415J2H1)
-
Chi, M.; Lin, M.; Huang, Y.; Chen, Y.; Wang, T.; Lin, L.
Enzymatic synthesis of L-theanine from L-glutamine and ethylamine by Bacillus licheniformis gamma-glutamyltranspeptidase and its mutants specialized in transpeptidase activity
Biocatal. Agricult. Biotechnol.
22
101393
2019
Bacillus licheniformis (A0A415J2H1)
-
Lisheng, X.; Guizhen, G.; Xingtao, Z.; Mengting, W.
Enzymatic synthesis of gamma-glutamylmethylamide from L-glutamylhydrazine and methylamine catalysed by immobilized recombinant gamma-glutamyltranspeptidase
Biocatal. Biotransform.
37
86-91
2019
Escherichia coli (P18956)
-
Watanabe, B.; Tabuchi, Y.; Wada, K.; Hiratake, J.
Synthesis and evaluation of the inhibitory activity of the four stereoisomers of the potent and selective human gamma-glutamyl transpeptidase inhibitor GGsTop
Bioorg. Med. Chem. Lett.
27
4920-4924
2017
Homo sapiens (P19440)
Hibi, T.; Imaoka, M.; Shimizu, Y.; Itoh, T.; Wakayama, M.
Crystal structure analysis and enzymatic characterization of gamma-glutamyltranspeptidase from Pseudomonas nitroreducens
Biosci. Biotechnol. Biochem.
83
262-269
2019
Pseudomonas nitroreducens (E0D5C2), Pseudomonas nitroreducens, Pseudomonas nitroreducens IFO12694 (E0D5C2), Pseudomonas nitroreducens IFO12694
Calvio, C.; Romagnuolo, F.; Vulcano, F.; Speranza, G.; Morelli, C.
Data for the synthesis of oligo-gamma-glutamylglutamines as model compounds for gamma-glutamyltransferases (GGTs) and for normalization of activities of different GGTs
Data Brief
21
576-581
2018
Bacillus subtilis (P54422), Bacillus subtilis, Bacillus subtilis 168 (P54422)
Bindal, S.; Dagar, V.; Saini, M.; Khasa, Y.; Gupta, R.
High level extracellular production of recombinant gamma-glutamyl transpeptidase from Bacillus licheniformis in Escherichia coli fed-batch culture
Enzyme Microb. Technol.
116
23-32
2018
Bacillus licheniformis (A9YTT0), Bacillus licheniformis, Bacillus licheniformis ER15 (A9YTT0)
Lee, Y.; Chi, M.; Lin, M.; Chen, Y.; Lin, L.; Wang, T.
Biocatalytic synthesis of gamma-glutamyl-L-leucine, a Kokumi-imparting dipeptide, by Bacillus licheniformis gamma-glutamyltranspeptidase
Food Biotechnol.
32
130-147
2018
Bacillus licheniformis
-
Sun, Y.; Hu, J.; Wang, W.; Zhang, B.; Shen, Y.
Characterization of gamma-glutamyltranspeptidases from dormant garlic and onion bulbs
Food Sci. Nutr.
7
499-505
2019
Allium cepa (Q6R2X1), Allium cepa, Allium sativum (A0A0B6VSN3), Allium sativum
Philips, J.; Dumin, W.; Winefield, C.
Functional characterization of the grapevine gamma-glutamyl transferase/transpeptidase (E.C. 2.3.2.2) gene family reveals a single functional gene whose encoded protein product is not located in either the vacuole or apoplast
Front. Plant Sci.
10
1402
2019
Vitis vinifera (A0A516F1V8)
Ni, F.; Zhang, F.; Yao, Z.; Ye, L.; Sun, Y.; Wang, H.; Zhou, Z.; Zhu, B.
Improving the catalytic properties and stability of immobilized gamma-glutamyltranspeptidase by post-immobilization with PharmalyteMT 8-10.5
Int. J. Biol. Macromol.
105
1581-1586
2017
Bacillus subtilis, Bacillus subtilis 168
Chi, M.; Lin, M.; Chen, Y.; Lin, L.; Wang, T.
Functional role of the conserved glycine residues, Gly481 and Gly482, of the gamma-glutamyltranspeptidase from Bacillus licheniformis
Int. J. Biol. Macromol.
109
1182-1188
2018
Bacillus licheniformis (A0A415J2H1), Bacillus licheniformis
Lin, M.; Chi, M.; Chen, Y.; Wang, T.; Lo, H.; Lin, L.
Site-directed mutagenesis of a conserved Asn450 residue of Bacillus licheniformis gamma-glutamyltranspeptidase
Int. J. Biol. Macromol.
91
416-425
2016
Bacillus licheniformis (Q62WE3), Bacillus licheniformis, Bacillus licheniformis DSM 13 (Q62WE3)
Bindal, S.; Gupta, R.
Thermo- and salt-tolerant chitosan cross-linked gamma-glutamyl transpeptidase from Bacillus licheniformis ER15
Int. J. Biol. Macromol.
91
544-553
2016
Bacillus licheniformis (A9YTT0), Bacillus licheniformis ER15 (A9YTT0)
Hillmann, H.; Behr, J.; Ehrmann, M.; Vogel, R.; Hofmann, T.
Formation of Kokumi-enhancing gamma-glutamyl dipeptides in Parmesan cheese by means of gamma-glutamyltransferase activity and stable isotope double-labeling studies
J. Agric. Food Chem.
64
1784-1793
2016
Bos taurus, no activity in Lactobacillus casei, no activity in Lactobacillus harbinensis
Mu, D.; Li, H.; Chen, Q.; Zhu, J.; Wu, X.; Luo, S.; Zhao, Y.; Wang, L.; Jiang, S.; Li, X.; Zheng, Z.
Secretion of Bacillus amyloliquefaciens gamma-glutamyltranspeptidase from Bacillus subtilis and its application in enzymatic synthesis of L-theanine
J. Agric. Food Chem.
67
14129-14136
2019
Bacillus amyloliquefaciens, Bacillus amyloliquefaciens BH072
Walter, F.; Grenz, S.; Ortseifen, V.; Persicke, M.; Kalinowski, J.
Corynebacterium glutamicum ggtB encodes a functional gamma-glutamyl transpeptidase with gamma-glutamyl dipeptide synthetic and hydrolytic activity
J. Biotechnol.
232
99-109
2016
Corynebacterium glutamicum (Q8NRT7), Corynebacterium glutamicum, Corynebacterium glutamicum LMG 3730 (Q8NRT7), Corynebacterium glutamicum ATCC 13032 (Q8NRT7), Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum JCM 1318 (Q8NRT7), Corynebacterium glutamicum NCIMB 10025 (Q8NRT7), Corynebacterium glutamicum DSM 20300 (Q8NRT7)
Liu, C.; Jia, J.; Wang, H.; Xue, L.; Kong, Y.; Wang, F.
Purification and characterization of a flavor-related enzyme, gamma-glutamyl-transpeptidase, from Toona sinensis leaves
J. Hortic. Sci. Biotechnol.
91
611-618
2016
Toona sinensis
-
Kim, J.; Jang, S.; Kim, A.; Su, H.; Gunawardhana, N.; Jeon, Y.; Bak, E.; Kim, J.; Cha, J.
Role of bacterial gamma-glutamyltranspeptidase as a novel virulence factor in bone-resorbing pathogenesis
J. Microbiol.
54
396-402
2016
Bacillus subtilis (P54422), Bacillus subtilis, Bacillus subtilis 168 (P54422)
Lee, J.; Lee, J.; Nam, G.; Son, B.; Jang, M.; Lee, S.; Hurh, B.; Kim, T.
Heterologous expression and enzymatic characterization of gamma-glutamyltranspeptidase from Bacillus amyloliquefaciens
J. Microbiol.
55
147-152
2017
Bacillus amyloliquefaciens (A0A1S5V3K5), Bacillus amyloliquefaciens, Bacillus velezensis (A7Z5E0), Bacillus subtilis (P54422), Bacillus subtilis, Bacillus licheniformis (Q65KZ6), Bacillus licheniformis, Bacillus subtilis 168 (P54422), Bacillus licheniformis NCIMB 9375 (Q65KZ6), Bacillus licheniformis Gibson 46 (Q65KZ6), Bacillus licheniformis JCM 2505 (Q65KZ6), Bacillus licheniformis NRRL NRS-1264 (Q65KZ6), Bacillus velezensis BGSC 10A6 (A7Z5E0), Bacillus velezensis DSM 23117 (A7Z5E0), Bacillus amyloliquefaciens SMB469 (A0A1S5V3K5), Bacillus licheniformis NBRC 12200 (Q65KZ6), Bacillus licheniformis ATCC 14580 (Q65KZ6), Bacillus velezensis FZB42 (A7Z5E0), Bacillus licheniformis DSM 13 (Q65KZ6)
Milito, A.; Brancaccio, M.; Lisurek, M.; Masullo, M.; Palumbo, A.; Castellano, I.
Probing the interactions of sulfur-containing histidine compounds with human gamma-glutamyl transpeptidase
Mar. Drugs
17
650
2019
Equus caballus (E5G727), Homo sapiens (P19440), Homo sapiens
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