Information on EC 2.4.1.168 - xyloglucan 4-glucosyltransferase

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
2.4.1.168
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RECOMMENDED NAME
GeneOntology No.
xyloglucan 4-glucosyltransferase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
Transfers a beta-D-glucosyl residue from UDP-glucose on to a glucose residue in xyloglucan, forming a beta-(1->4)-D-glucosyl-D-glucose linkage
show the reaction diagram
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hexosyl group transfer
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
xyloglucan biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
UDP-glucose:xyloglucan 4-beta-D-glucosyltransferase
In association with EC 2.4.2.39 (xyloglucan 6-xylosyltransferase), this enzyme brings about the synthesis of xyloglucan; concurrent transfers of glucose and xylose are essential for this synthesis. Not identical with EC 2.4.1.12 cellulose synthase (UDP-forming).
CAS REGISTRY NUMBER
COMMENTARY hide
80237-91-8
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
tamarind
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-
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
UDP-D-glucose + (glucosyl)xyloglucan
UDP + (glucosyl-glucosyl)xyloglucan
show the reaction diagram
UDP-D-glucose + xyloglucan
UDP + glucosylxyloglucan
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
UDP-D-glucose + xyloglucan
UDP + glucosylxyloglucan
show the reaction diagram
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
-
no activation by Ca2+
INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
GTPglucose
TDPglucose
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weak
UDP-xylose
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above 0.03 mM
additional information
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no inhibition by tunicamycin, ATP or GTP
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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
UDP-xylose
additional information
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fusicoccin, indole acetic acid and D2O activate in vivo, via proton extrusion, in the presence of O2 and sugar substrate, while mannitol, vanadate or nigrecin inhibit this activation, no direct activation in vitro
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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.056
UDPglucose
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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6.5 - 7
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7 - 8
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TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
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elongation region
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
DTT, 1 mM, EDTA, 1 mM, sucrose, 0.4 M, bovine serum albumin, 0.1%, stabilize
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STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
0°C, crude membrane-bound enzyme preparation, 1 day
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