Information on EC 2.4.1.188 - N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase

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The expected taxonomic range for this enzyme is: Bacillus coagulans

EC NUMBER
COMMENTARY hide
2.4.1.188
-
RECOMMENDED NAME
GeneOntology No.
N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
UDP-alpha-D-glucose + N-acetyl-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol = UDP + beta-D-glucosyl-(1->4)-N-acetyl-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
show the reaction diagram
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hexosyl group transfer
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
UDP-glucose:N-acetyl-D-glucosaminyldiphosphoundecaprenol 4-beta-D-glucosyltransferase
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CAS REGISTRY NUMBER
COMMENTARY hide
118731-83-2
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
AHU 1366
-
-
Manually annotated by BRENDA team
AHU 1366
-
-
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
UDP-glucose + N-acetyl-D-glucosaminyldiphosphoundecaprenol
UDP + beta-D-glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
UDP-glucose + N-acetyl-D-glucosaminyldiphosphoundecaprenol
UDP + beta-D-glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol
show the reaction diagram
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(NH4)2SO4
-
stimulation
glycerol
-
at 20% stimulates 3fold
KCl
-
at 0.6 M stimulation
MgCl2
-
at 40 mM stimulation
NaCl
-
stimulation
NH4Cl
-
stimulation
Nonidet P-40
-
at 0.1% slight stimulatory
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.021
UDP-glucose
-
-
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
25
-
assay at
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
stabilization of the solubilized enzyme by cations and glycerol
-
STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
-18°C, several months without significant loss of activity
-
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE