Reference on EC 2.4.1.288 - galactofuranosylgalactofuranosylrhamnosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,5/1,6-galactofuranosyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
May, J.F.; Levengood, M.R.; Splain, R.A.; Brown, C.D.; Kiessling, L.L.
A processive carbohydrate polymerase that mediates bifunctional catalysis using a single active site
Biochemistry
51
1148-1159
2012
Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
Rose, N.L.; Zheng, R.B.; Pearcey, J.; Zhou, R.; Completo, G.C.; Lowary, T.L.
Development of a coupled spectrophotometric assay for GlfT2, a bifunctional mycobacterial galactofuranosyltransferase
Carbohydr. Res.
343
2130-2139
2008
Mycobacterium tuberculosis
Szczepina, M.G.; Zheng, R.B.; Completo, G.C.; Lowary, T.L.; Pinto, B.M.
STD-NMR studies suggest that two acceptor substrates for GlfT2, a bifunctional galactofuranosyltransferase required for the biosynthesis of Mycobacterium tuberculosis arabinogalactan, compete for the same binding site
ChemBioChem
10
2052-2059
2009
Mycobacterium tuberculosis
Brown, C.D.; Rusek, M.S.; Kiessling, L.L.
Fluorosugar chain termination agents as probes of the sequence specificity of a carbohydrate polymerase
J. Am. Chem. Soc.
134
6552-6555
2012
Mycobacterium tuberculosis
Mikusova, K.; Belanova, M.; Kordulakova, J.; Honda, K.; McNeil, M.; Mahapatra, S.; Crick, D.; Brennan, P.
Identification of a novel galactosyl transferase involved in biosynthesis of the mycobacterial cell wall
J. Bacteriol.
188
6592-6598
2006
Mycobacterium tuberculosis
Belanova, M.; Dianiskova, P.; Brennan, P.J.; Completo, G.C.; Rose, N.L.; Lowary, T.L.; Mikusova, K.
Galactosyl transferases in mycobacterial cell wall synthesis
J. Bacteriol.
190
1141-1145
2008
Mycolicibacterium smegmatis
Wheatley, R.W.; Zheng, R.B.; Richards, M.R.; Lowary, T.L.; Ng, K.K.
Tetrameric structure of the GlfT2 galactofuranosyltransferase reveals a scaffold for the assembly of mycobacterial arabinogalactan
J. Biol. Chem.
287
28132-28143
2012
Mycobacterium tuberculosis (O53585)
Poulin, M.B.; Zhou, R.; Lowary, T.L.
Synthetic UDP-galactofuranose analogs reveal critical enzyme-substrate interactions in GlfT2-catalyzed mycobacterial galactan assembly
Org. Biomol. Chem.
10
4074-4087
2012
Mycobacterium tuberculosis
May, J.F.; Splain, R.A.; Brotschi, C.; Kiessling, L.L.
A tethering mechanism for length control in a processive carbohydrate polymerization
Proc. Natl. Acad. Sci. USA
106
11851-11856
2009
Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
Dumitrescu, L.; Eppe, G.; Tikad, A.; Pan, W.; El Bkassiny, S.; Gurcha, S.; Arda, A.; Jimenez-Barbero, J.; Besra, G.; Vincent, S.
Selectfluor and NFSI exo-glycal fluorination strategies applied to the enhancement of the binding affinity of galactofuranosyltransferase GlfT2 inhibitors
Chemistry
20
15208-15215
2014
Mycobacterium tuberculosis (O53585), Mycobacterium tuberculosis ATCC 25618 (O53585)
Li, J.; Lowary, T.
Sulfonium ions as inhibitors of the mycobacterial galactofuranosyltransferase GlfT2
MedChemComm
5
1130-1137
2014
Mycobacterium tuberculosis (O53585), Mycobacterium tuberculosis ATCC 25618 (O53585)
-
Janos, P.; Kozmon, S.; Tvaroska, I.; Koca, J.
How Mycobacterium tuberculosis galactofuranosyl transferase 2 (GlfT2) generates alternating beta-(1-6) and beta-(1-5) linkages A QM/MM molecular dynamics study of the chemical steps
Chemistry
24
7051-7059
2018
Mycobacterium tuberculosis (O53585), Mycobacterium tuberculosis, Mycobacterium tuberculosis ATCC 25618 (O53585)
Yamatsugu, K.; Splain, R.A.; Kiessling, L.L.
Fidelity and promiscuity of a mycobacterial glycosyltransferase
J. Am. Chem. Soc.
138
9205-9211
2016
Mycobacterium tuberculosis (O53585), Mycobacterium tuberculosis, Mycobacterium tuberculosis ATCC 25618 (O53585)
Lowary, T.; Li, J.
Synthesis and evaluation of bicyclo[3.1.0]hexane-based UDP-Galf analogues as inhibitors of the mycobacterial galactofuranosyltransferase GlfT2
Molecules
21
1053
2016
Mycobacterium tuberculosis (O53585), Mycobacterium tuberculosis ATCC 25618 (O53585)
Ati, J.; Colas, C.; Lafite, P.; Sweeney, R.P.; Zheng, R.B.; Lowary, T.L.; Daniellou, R.
The LPG1x family from Leishmania major is constituted of rare eukaryotic galactofuranosyltransferases with unprecedented catalytic properties
Sci. Rep.
8
17566
2018
Leishmania major (Q4QD44), Leishmania major (Q6XFB6), Leishmania major (Q9NC61), Leishmania major
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