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beta-nicotinate D-ribonucleotide + diphosphate + CO2
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
M1KCW7
-
-
-
?
nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O
beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate
phosphoribosyl diphosphate + quinolinic acid
nicotinate mononucleotide + diphosphate + CO2
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
beta-nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate + H+
beta-nicotinate D-ribonucleotide + diphosphate + CO2
quinolinic acid + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinic acid mononucleotide + diphosphate + CO2
additional information
?
-
nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O
beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate
-
-
-
-
?
nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O
beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate
-
-
-
-
?
phosphoribosyl diphosphate + quinolinic acid
nicotinate mononucleotide + diphosphate + CO2
-
-
-
-
r
phosphoribosyl diphosphate + quinolinic acid
nicotinate mononucleotide + diphosphate + CO2
-
-
-
r
phosphoribosyl diphosphate + quinolinic acid
nicotinate mononucleotide + diphosphate + CO2
-
-
-
-
r
phosphoribosyl diphosphate + quinolinic acid
nicotinate mononucleotide + diphosphate + CO2
-
-
-
r
phosphoribosyl diphosphate + quinolinic acid
nicotinate mononucleotide + diphosphate + CO2
-
-
-
r
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
essential enzyme in the NAD+ biosynthetic pathway
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
ir
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
type II phosphoribosyltransfer followed by irreversible decarboxylation, involved in catabolism of quinolinic acid and in NAD+ de novo synthesis
-
-
ir
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
i.e. beta-niacin mononucleotide
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
enzyme provides the de novo source of nicotinate mononucleotide
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
enzyme provides the de novo source of nicotinate mononucleotide
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
synthesis of precursors for trigonelline biosynthesis, feeding experiments, overview
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
direct conversion of quinolinic acid to nicotinic acid mononucleotide
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate + H+
beta-nicotinate D-ribonucleotide + diphosphate + CO2
-
Burkholderia sp. strain PsJN stimulates root growth of potato explants compared to uninoculated controls under gnotobiotic conditions. QAPRTase may play a role in the signal pathway for promotion of plant growth by PsJN
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate + H+
beta-nicotinate D-ribonucleotide + diphosphate + CO2
-
Burkholderia sp. strain PsJN stimulates root growth of potato explants compared to uninoculated controls under gnotobiotic conditions. QAPRTase may play a role in the signal pathway for promotion of plant growth by PsJN
-
-
?
quinolinic acid + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinic acid mononucleotide + diphosphate + CO2
-
-
-
?
quinolinic acid + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinic acid mononucleotide + diphosphate + CO2
-
-
-
-
?
quinolinic acid + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinic acid mononucleotide + diphosphate + CO2
6 mM MgCl2, pH7.2, 37°C, 0.3 mM quinolinic acid, HPLC-based assay: 7 microgram purified enzyme, 1 mM 5-phospho-alpha-D-ribose 1-diphosphate, 20 min, UV-based assay: 14 microgram purified enzyme, 0.1 mM 5-phospho-alpha-D-ribose 1-diphosphate, 30 min
HPLC-based assay: 254 nm (quantification of nicotinic acid mononucleotide and quinolinic acid), UV-based assay: 266 nm (quantification of nicotinic acid mononucleotide)
-
ir
quinolinic acid + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinic acid mononucleotide + diphosphate + CO2
-
-
-
?
quinolinic acid + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinic acid mononucleotide + diphosphate + CO2
-
-
-
?
quinolinic acid + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinic acid mononucleotide + diphosphate + CO2
-
-
-
?
quinolinic acid + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinic acid mononucleotide + diphosphate + CO2
-
Arg175 is essential for catalysis, critical role for Lys185 in the chemistry of the QAPRTase intermediate, interfacial role for Arg118 during catalysis
-
-
?
quinolinic acid + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinic acid mononucleotide + diphosphate + CO2
-
Lys153 is necessary for catalysis and important for 5-phospho-alpha-D-ribose 1-diphosphate binding, Glu214 provides a hydrogen bond necessary for catalysis but does not act as a base or electrostatically to stabilize the transition state, Lys284 is involved in 5-phospho-alpha-D-ribose 1-diphosphate binding, and Asp235 is not essential
-
-
?
additional information
?
-
-
the recruitment of this gene for growth on phthalate gives Burkholderia cepacia an advantage over other phthalate-degrading bacteria in the environment
-
-
?
additional information
?
-
-
key enzyme of NAD+ biosynthesis
-
-
?
additional information
?
-
-
key enzyme in catabolism of quinolinate. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders
-
-
?
additional information
?
-
no detectable activity for mutants R161Q, R138Q, K171A, K171S, K139A, K139S, 6 mM MgCl2, pH7.2, 37°C, 0.3 mM quinolinic acid, UV-based assay: 14 microgram purified enzyme, 0.1 mM 5-phospho-alpha-D-ribose 1-diphosphate, 30 min
-
-
?
additional information
?
-
-
no detectable activity for mutants R161Q, R138Q, K171A, K171S, K139A, K139S, 6 mM MgCl2, pH7.2, 37°C, 0.3 mM quinolinic acid, UV-based assay: 14 microgram purified enzyme, 0.1 mM 5-phospho-alpha-D-ribose 1-diphosphate, 30 min
-
-
?
additional information
?
-
-
essential enzyme for the de novo biosynthesis of NAD+
-
-
?
additional information
?
-
-
key enzyme in NAD+ biosynthesis, also plays an important role in ensuring nicotinic acid available for the synthesis of defensive pyridine alkaloids
-
-
?
additional information
?
-
-
key enzyme in NAD+ biosynthesis, also plays an important role in ensuring nicotinic acid available for the synthesis of defensive pyridine alkaloids
-
-
?
additional information
?
-
-
key enzyme in NAD+ biosynthesis, also plays an important role in ensuring nicotinic acid available for the synthesis of defensive pyridine alkaloids
-
-
?
additional information
?
-
-
enzyme is probably involved in the regulation of nicotine biosynthesis
-
-
?
additional information
?
-
-
enzyme of the kynurenine pathway
-
-
?
additional information
?
-
-
intermediary enzyme in the de novo NAD biosynthetic pathway
-
-
?
additional information
?
-
-
intermediary enzyme in the de novo NAD biosynthetic pathway
-
-
?
additional information
?
-
-
intermediary enzyme in the de novo NAD biosynthetic pathway
-
-
?
additional information
?
-
-
intermediary enzyme in the de novo NAD biosynthetic pathway
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
beta-nicotinate D-ribonucleotide + diphosphate + CO2
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
M1KCW7
-
-
-
?
phosphoribosyl diphosphate + quinolinic acid
nicotinate mononucleotide + diphosphate + CO2
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
beta-nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate + H+
beta-nicotinate D-ribonucleotide + diphosphate + CO2
quinolinic acid + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinic acid mononucleotide + diphosphate + CO2
additional information
?
-
phosphoribosyl diphosphate + quinolinic acid
nicotinate mononucleotide + diphosphate + CO2
-
-
-
-
r
phosphoribosyl diphosphate + quinolinic acid
nicotinate mononucleotide + diphosphate + CO2
-
-
-
r
phosphoribosyl diphosphate + quinolinic acid
nicotinate mononucleotide + diphosphate + CO2
-
-
-
-
r
phosphoribosyl diphosphate + quinolinic acid
nicotinate mononucleotide + diphosphate + CO2
-
-
-
r
phosphoribosyl diphosphate + quinolinic acid
nicotinate mononucleotide + diphosphate + CO2
-
-
-
r
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
essential enzyme in the NAD+ biosynthetic pathway
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
type II phosphoribosyltransfer followed by irreversible decarboxylation, involved in catabolism of quinolinic acid and in NAD+ de novo synthesis
-
-
ir
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
enzyme provides the de novo source of nicotinate mononucleotide
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
enzyme provides the de novo source of nicotinate mononucleotide
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinate D-ribonucleotide + diphosphate + CO2
-
synthesis of precursors for trigonelline biosynthesis, feeding experiments, overview
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate + H+
beta-nicotinate D-ribonucleotide + diphosphate + CO2
-
Burkholderia sp. strain PsJN stimulates root growth of potato explants compared to uninoculated controls under gnotobiotic conditions. QAPRTase may play a role in the signal pathway for promotion of plant growth by PsJN
-
-
?
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate + H+
beta-nicotinate D-ribonucleotide + diphosphate + CO2
-
Burkholderia sp. strain PsJN stimulates root growth of potato explants compared to uninoculated controls under gnotobiotic conditions. QAPRTase may play a role in the signal pathway for promotion of plant growth by PsJN
-
-
?
quinolinic acid + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinic acid mononucleotide + diphosphate + CO2
-
-
-
?
quinolinic acid + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinic acid mononucleotide + diphosphate + CO2
-
-
-
-
?
quinolinic acid + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinic acid mononucleotide + diphosphate + CO2
-
-
-
?
quinolinic acid + 5-phospho-alpha-D-ribose 1-diphosphate
nicotinic acid mononucleotide + diphosphate + CO2
-
-
-
?
additional information
?
-
-
the recruitment of this gene for growth on phthalate gives Burkholderia cepacia an advantage over other phthalate-degrading bacteria in the environment
-
-
?
additional information
?
-
-
key enzyme of NAD+ biosynthesis
-
-
?
additional information
?
-
-
key enzyme in catabolism of quinolinate. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders
-
-
?
additional information
?
-
-
essential enzyme for the de novo biosynthesis of NAD+
-
-
?
additional information
?
-
-
key enzyme in NAD+ biosynthesis, also plays an important role in ensuring nicotinic acid available for the synthesis of defensive pyridine alkaloids
-
-
?
additional information
?
-
-
key enzyme in NAD+ biosynthesis, also plays an important role in ensuring nicotinic acid available for the synthesis of defensive pyridine alkaloids
-
-
?
additional information
?
-
-
key enzyme in NAD+ biosynthesis, also plays an important role in ensuring nicotinic acid available for the synthesis of defensive pyridine alkaloids
-
-
?
additional information
?
-
-
enzyme is probably involved in the regulation of nicotine biosynthesis
-
-
?
additional information
?
-
-
enzyme of the kynurenine pathway
-
-
?
additional information
?
-
-
intermediary enzyme in the de novo NAD biosynthetic pathway
-
-
?
additional information
?
-
-
intermediary enzyme in the de novo NAD biosynthetic pathway
-
-
?
additional information
?
-
-
intermediary enzyme in the de novo NAD biosynthetic pathway
-
-
?
additional information
?
-
-
intermediary enzyme in the de novo NAD biosynthetic pathway
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Packman, P.M.; Jacoby, W.B.
Crystalline quinolinate phosphoribosyltransferase
J. Biol. Chem.
240
PC4107-PC4108
1965
Pseudomonas sp.
-
brenda
Gholson, R.K.; Ueda, I.; Ogasawara, N.; Henderson, L.M.
The enzymatic conversion of quinolinate to nicotinic acid mononucleotide in mammalian liver
J. Biol. Chem.
239
1208-1214
1964
Bos taurus
brenda
Taguchi, H.; Iwai, K.
Purification and properties of quinolinate phosphoribosyltransferase from the Shiitake mushroom (Lentinus edodes)
J. Nutr. Sci. Vitaminol.
20
269-281
1974
Lentinula edodes
brenda
Taguchi, H.; Iwai, K.
Characteristics of quinolinate phosphoribosyltransferase from the Shiitake mushroom (Lentinus edodes)
J. Nutr. Sci. Vitaminol.
20
283-291
1974
Lentinula edodes
brenda
Wagner, R.; Wagner, K.G.
Determination of quinolinic acid phosphoribosyltransferase in tobacco
Phytochemistry
23
1881-1883
1984
Nicotiana tabacum
-
brenda
Iwai, K.; Taguchi, H.
Crystallization and properties of quinolinate phosphoribosyltransferase from hog liver
Methods Enzymol.
66
96-101
1980
Sus scrofa
brenda
Mann, D.F.; Byerrum, R.U.
Quinolinic acid phosphoribosyltransferase from castor bean endosperm. I. Purification and characterization
J. Biol. Chem.
249
6817-6823
1974
Ricinus communis
brenda
Shibata, K.; Iwai, K.
Effect of 5-phosphoribosyl-1-pyrophosphate on crystalline quinolinate phosphoribosyltransferase activities from hog kidney and hog liver
Agric. Biol. Chem.
44
2785-2791
1980
Sus scrofa
-
brenda
Taguchi, H.; Iwai, K.
Inhibition of hog liver crystalline quinolinate phosphoribosyltransferase by nucleotides, quinolinate analogues and sulfhydryl reagents
Agric. Biol. Chem.
40
385-389
1976
Sus scrofa
-
brenda
Musick, W.D.L.
Preliminary crystallographic studies on quinolinate phosphoribosyltransferase
J. Mol. Biol.
117
1101-1107
1977
Sus scrofa
brenda
Bhatia, R.; calvo, K.C.
The sequencing, expression, purification, and steady-state kinetic analysis of quinolinate phosphoribosyl transferase from Escherichia coli
Arch. Biochem. Biophys.
325
270-278
1996
Escherichia coli (P30011), Escherichia coli
brenda
Iwai, K.; Shibata, K.; Taguchi, H.
Crystalline quinolinate phosphoribosyltransferase from hog liver: the molecular weight and some enzymic properties
Agric. Biol. Chem.
43
351-355
1979
Sus scrofa
-
brenda
Hughes, K.T.; Dessen, A.; Gray, J.P.; Grubmeyer, C.
The Salmonella typhimurium nadC gene: sequence determination by use of Mud-P22 and purification of quinolinate phosphoribosyltransferase
J. Bacteriol.
175
479-486
1993
Salmonella enterica subsp. enterica serovar Typhimurium
brenda
Iwai, K.; Taguchi, H.
Purification and crystallization of quinolinate phosphoribosyltransferase from hog liver
Biochem. Biophys. Res. Commun.
56
884-891
1974
Sus scrofa
brenda
Taguchi, H.; Iwai, K.
The isolation and physicochemical properties of crystalline quinolinate phosphoribosyltransferase from hog liver
Agric. Biol. Chem.
39
1493-1500
1975
Sus scrofa
-
brenda
Taguchi, H.; Iwai, K.
Properties of the crystalline quinolinate phosphoribosyltransferase from hog liver
Agric. Biol. Chem.
39
1599-1604
1975
Sus scrofa
-
brenda
Okuno, E.; Schwarcz, R.
Purification of quinolinic acid phosphoribosyltransferase from rat liver and brain
Biochim. Biophys. Acta
841
112-119
1985
Rattus norvegicus
brenda
Okuno, E.; White, R.J.; Schwarcz, R.
Quinolinic acid phosphoribosyltransferase: purification and partial characterization from human liver and brain
J. Biochem.
103
1054-1059
1988
Homo sapiens
brenda
Shibata, K.; Iwai, K.
Isolation and properties of crystalline quinolinate phosphoribosyltransferase from hog kidney
Biochim. Biophys. Acta
611
280-288
1980
Sus scrofa
brenda
Iwai, K.; Shibata, K.; Taguchi, H.; Itakura, T.
Properties of crystalline quinolinate phosphoribosyltransferase from Alcaligenes eutrophus nov. Subsp. Quinolinicus
Agric. Biol. Chem.
43
345-350
1979
Cupriavidus necator
-
brenda
Shibata, K.; Iwai, K.
Crystalline quinolinate phosphoribosyltransferase from Alcaligenes eutrophus subsp. quinolinicus: effects of metal ions, phosphorous-compounds, niacin nucleotides and glycerol
Agric. Biol. Chem.
44
119-123
1980
Cupriavidus necator
-
brenda
Panozzo, C.; Nawara, M.; Suski, C.; Kucharczyka, R.; Skoneczny, M.; Becam, A.M.; Rytka, J.; Herbert, C.J.
Aerobic and anaerobic NAD+ metabolism in Saccharomyces cerevisiae
FEBS Lett.
517
97-102
2002
Saccharomyces cerevisiae
brenda
Kim, M.K.; Kim, Y.S.; Rho, S.H.; Im, Y.J.; Lee, J.H.; Kang, G.B.; Eom, S.H.
Crystallization and preliminary X-ray crystallographic analysis of quinolinate phosphoribosyltransferase of Helicobacter pylori
Acta Crystallogr. Sect. D
59
1265-1266
2003
Helicobacter pylori
brenda
Chang, H.K.; Zylstra, G.J.
Role of quinolinate phosphoribosyltransferase in degradation of phthalate by Burkholderia cepacia DBO1
J. Bacteriol.
181
3069-3075
1999
Burkholderia cepacia
brenda
Sinclair, S.J.; Murphy, K.J.; Birch, C.D.; Hamill, J.D.
Molecular characterization of quinolinate phosphoribosyltransferase (QPRTase) in Nicotiana
Plant Mol. Biol.
44
603-617
2000
Nicotiana rustica, Nicotiana sylvestris, Nicotiana tabacum
brenda
Cao, H.; Pietrak, B.L.; Grubmeyer, C.
Quinolinate phosphoribosyltransferase: kinetic mechanism for a type II PRTase
Biochemistry
41
3520-3528
2002
Salmonella enterica subsp. enterica serovar Typhimurium
brenda
Fukuoka, S.I.; Nyaruhucha, C.M.; Shibata, K.
Characterization and functional expression of the cDNA encoding human brain quinolinate phosphoribosyltransferase
Biochim. Biophys. Acta
1395
192-201
1998
Homo sapiens
brenda
Sharma, V.; Grubmeyer, C.; Sacchettini, J.C.
Crystal structure of quinolinic acid phosphoribosyltransferase from Mycobacterium tuberculosis: a potential TB drug target
Structure
6
1587-1599
1998
Mycobacterium tuberculosis
brenda
Eads, J.C.; Ozturk, D.; Wexler, T.B.; Grubmeyer, C.; Sacchettini, J.C.
A new function for a common fold: the crystal structure of quinolinic acid phosphoribosyltransferase
Structure
5
47-58
1997
Salmonella enterica subsp. enterica serovar Typhimurium
brenda
Zheng, X.Q.; Hayashibe, E.; Ashihara, H.
Changes in trigonelline (N-methylnicotinic acid) content and nicotinic acid metabolism during germination of mungbean (Phaseolus aureus) seeds
J. Exp. Bot.
56
1615-1623
2005
Vigna radiata var. radiata
brenda
Schwarzenbacher, R.; Jaroszewski, L.; Von Delft, F.; Abdubek, P.; Ambing, E.; Biorac, T.; Brinen, L.S.; Canaves, J.M.; Cambell, J.; Chiu, H.J.; et al.
Crystal structure of a type II quinolic acid phosphoribosyltransferase (TM1645) from Thermotoga maritima at 2.50 A resolution
Proteins Struct. Funct. Bioinform.
55
768-771
2004
Thermotoga maritima (Q9X1X8), Thermotoga maritima, Thermotoga maritima MSB8 / DSM 3109 / ATCC 43589 (Q9X1X8)
brenda
Wang, K.; Conn, K.; Lazarovits, G.
Involvement of quinolinate phosphoribosyl transferase in promotion of potato growth by a Burkholderia strain
Appl. Environ. Microbiol.
72
760-768
2006
Burkholderia sp., Burkholderia sp. PsJN
brenda
Kim, M.; Im, Y.J.; Lee, J.H.; Eom, S.H.
Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori
Proteins
63
252-255
2006
Helicobacter pylori (O25909), Helicobacter pylori
brenda
Liu, H.; Woznica, K.; Catton, G.; Crawford, A.; Botting, N.; Naismith, J.H.
Structural and kinetic characterization of quinolinate phosphoribosyltransferase (hQPRTase) from Homo sapiens
J. Mol. Biol.
373
755-763
2007
Homo sapiens (Q15274), Homo sapiens
brenda
di Luccio, E.; Wilson, D.K.
Comprehensive X-ray structural studies of the quinolinate phosphoribosyl transferase (BNA6) from Saccharomyces cerevisiae
Biochemistry
47
4039-4050
2008
Saccharomyces cerevisiae (P43619), Saccharomyces cerevisiae
brenda
Bello, Z.; Stitt, B.; Grubmeyer, C.
Interactions at the 2 and 5 positions of 5-phosphoribosyl pyrophosphate are essential in Salmonella typhimurium quinolinate phosphoribosyltransferase
Biochemistry
49
1377-1387
2010
Salmonella enterica subsp. enterica serovar Typhimurium
brenda
Bello, Z.; Grubmeyer, C.
Roles for cationic residues at the quinolinic acid binding site of quinolinate phosphoribosyltransferase
Biochemistry
49
1388-1395
2010
Salmonella enterica subsp. enterica serovar Typhimurium
brenda
Kang, G.B.; Kim, M.K.; Youn, H.S.; An, J.Y.; Lee, J.G.; Park, K.R.; Lee, S.H.; Kim, Y.; Fukuoka, S.; Eom, S.H.
Crystallization and preliminary X-ray crystallographic analysis of human quinolinate phosphoribosyltransferase
Acta Crystallogr. Sect. F
67
38-40
2011
Homo sapiens
brenda
Youn, H.S.; Kim, M.K.; Kang, G.B.; Kim, T.G.; An, J.Y.; Lee, J.G.; Park, K.R.; Lee, Y.; Fukuoka, S.; Eom, S.H.
Crystallization and preliminary X-ray crystallographic analysis of quinolinate phosphoribosyltransferase from porcine kidney in complex with nicotinate mononucleotide
Acta Crystallogr. Sect. F
68
1488-1490
2012
Sus scrofa
brenda
Ishidoh, K.; Kamemura, N.; Imagawa, T.; Oda, M.; Sakurai, J.; Katunuma, N.
Quinolinate phosphoribosyl transferase, a key enzyme in de novo NAD(+) synthesis, suppresses spontaneous cell death by inhibiting overproduction of active-caspase-3
Biochim. Biophys. Acta
1803
527-533
2010
Homo sapiens (Q15274)
brenda
Ryan, S.M.; Cane, K.A.; DeBoer, K.D.; Sinclair, S.J.; Brimblecombe, R.; Hamill, J.D.
Structure and expression of the quinolinate phosphoribosyltransferase (QPT) gene family in Nicotiana
Plant Sci.
188-189
102-110
2012
Nicotiana tabacum (Q0WX54), Nicotiana tabacum (Q0WX55), Nicotiana tabacum
brenda
Sorci, L.; Blaby,I.K.; Rodionova, I.A.; De Ingeniis, J.; Tkachenko, S.; de Crcy-Lagard, V.; Osterman, A.L.
uinolinate salvage and insights for targeting NAD biosynthesis in group A streptococci
J. Bacteriol.
195
726-732
2013
Streptococcus pyogenes (Q5XBL7), Streptococcus pyogenes ATCC BAA-946 (Q5XBL7)
brenda
Youn, H.S.; Kim, M.K.; Kang, G.B.; Kim, T.G.; Lee, J.G.; An, J.Y.; Park, K.R.; Lee, Y.; Kang, J.Y.; Song, H.E.; Park, I.; Cho, C.; Fukuoka, S.; Eom, S.H.
Crystal structure of Sus scrofa quinolinate phosphoribosyltransferase in complex with nicotinate mononucleotide
PLoS ONE
8
e62027
2013
Sus scrofa (M1KCW7), Sus scrofa
brenda
Kim, H.; Shibayama, K.; Rimbara, E.; Mori, S.
Biochemical characterization of quinolinic acid phosphoribosyltransferase from Mycobacterium tuberculosis H37Rv and inhibition of its activity by pyrazinamide
PLoS ONE
9
e100062
2014
Mycobacterium tuberculosis (P9WJJ7), Mycobacterium tuberculosis H37Rv (P9WJJ7), Mycobacterium tuberculosis H37Rv
brenda
Malik, S.S.; Patterson, D.N.; Ncube, Z.; Toth, E.A.
The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid
Proteins
82
405-414
2014
Homo sapiens (Q15274), Homo sapiens
brenda
Youn, H.S.; Kim, T.G.; Kim, M.K.; Kang, G.B.; Kang, J.Y.; Lee, J.G.; An, J.Y.; Park, K.R.; Lee, Y.; Im, Y.J.; Lee, J.H.; Eom, S.H.
Structural insights into the quaternary catalytic mechanism of hexameric human quinolinate phosphoribosyltransferase, a key enzyme in de novo NAD biosynthesis
Sci. Rep.
6
19681
2016
Homo sapiens (Q15274), Homo sapiens
brenda
Ullmark, T.; Montano, G.; Jaervstrat, L.; Jernmark Nilsson, H.; Hakansson, E.; Drott, K.; Nilsson, B.; Vidovic, K.; Gullberg, U.
Anti-apoptotic quinolinate phosphoribosyltransferase (QPRT) is a target gene of Wilms tumor gene 1 (WT1) protein in leukemic cells
Biochem. Biophys. Res. Commun.
482
802-807
2017
Homo sapiens (Q15274)
brenda
Booth, W.T.; Morris, T.L.; Mysona, D.P.; Shah, M.J.; Taylor, L.K.; Karlin, T.W.; Clary, K.; Majorek, K.A.; Offermann, L.R.; Chruszcz, M.
Streptococcus pyogenes quinolinate-salvage pathway-structural and functional studies of quinolinate phosphoribosyl transferase and NH3 -dependent NAD+ synthetase
FEBS J.
284
2425-2441
2017
Streptococcus pyogenes serotype M4 (Q1J647), Streptococcus pyogenes serotype M4 MGAS 10750 (Q1J647)
brenda
Khan, S.; Pandey, S.S.; Jyotshna, S.S.; Shanker, K.; Khan, F.; Rahman, L.U.
Cloning and functional characterization of quinolinic acid phosphoribosyl transferase (QPT) gene of Nicotiana tabacum
Physiol. Plant.
160
253-265
2017
Nicotiana tabacum
brenda
Wang, Z.; Gao, Y.; Zhang, C.; Hu, H.; Guo, D.; Xu, Y.; Xu, Q.; Zhang, W.; Deng, S.; Lv, P.; Yang, Y.; Ding, Y.; Li, Q.; Weng, C.; Chen, X.; Gong, S.; Chen, H.; Niu, J.; Tang, H.
Quinolinate phosphoribosyltransferase is an antiviral host factor against hepatitis C virus infection
Sci. Rep.
7
5876
2017
Homo sapiens (Q15274), Homo sapiens
brenda
Singh, P.; Prasad, R.; Tewari, R.; Jaidi, M.; Kumar, S.; Rout, P.K.; Rahman, L.U.
Silencing of quinolinic acid phosphoribosyl transferase (QPT) gene for enhanced production of scopolamine in hairy root culture of Duboisia leichhardtii
Sci. Rep.
8
13939
2018
Duboisia leichhardtii
brenda