Information on EC 2.4.2.53 - undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Select one or more organisms in this record:
Show additional data
Do not include text mining results
Include (text mining) results (more...)
Include results (AMENDA + additional results, but less precise; more...)

The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
2.4.2.53
-
RECOMMENDED NAME
GeneOntology No.
undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
UDP-4-deoxy-4-formamido-beta-L-arabinopyranose + ditrans,octacis-undecaprenyl phosphate = UDP + 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate
show the reaction diagram
-
-
-
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
polymyxin resistance
-
-
Amino sugar and nucleotide sugar metabolism
-
-
SYSTEMATIC NAME
IUBMB Comments
UDP-4-amino-4-deoxy-alpha-L-arabinose:ditrans,octacis-undecaprenyl phosphate 4-amino-4-deoxy-alpha-L-arabinosyltransferase
The enzyme shows no activity with UDP-4-amino-4-deoxy-beta-L-arabinose.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
UDP-4-deoxy-4-formamido-beta-L-arabinopyranose + ditrans,polycis-undecaprenyl phosphate
UDP + 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans,polycis-undecaprenyl phosphate
show the reaction diagram
-
-
-
-
?
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
low Mg2+/Ca2+ concentration of 1 mM and a pH decrease from 8 to 6 both induce polymyxin resistance. Transcription of the pmrF operon in Yersinia pseudotuberculosis increases accordingly, by a factor of 7 and 2.5 for the Mg2+/Ca2+ ion starvation and acidic pH conditions, respectively
pmrF expression is independent of polymyxin resistance proteins PmrA-PmrB in Yersinia pseudotuberculosis, with the response regulator PhoP interacting directly with the pmrF operon promoter region
Show AA Sequence (1330 entries)
Please use the Sequence Search for a certain query.