Reference on EC 2.5.1.1 - dimethylallyltranstransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Vandermoten, S.; Santini, S.; Haubruge, E.; Heuze, F.; Francis, F.; Brasseur, R.; Cusson, M.; Charloteaux, B.
Structural features conferring dual geranyl/farnesyl diphosphate synthase activity to an aphid prenyltransferase
Insect Biochem. Mol. Biol.
39
707-716
2009
Acyrthosiphon pisum (Q1X877)
Lewis, M.J.; Prosser, I.M.; Mohib, A.; Field, L.M.
Cloning and characterisation of a prenyltransferase from the aphid Myzus persicae with potential involvement in alarm pheromone biosynthesis
Insect Mol. Biol.
17
437-443
2008
Myzus persicae (Q1X876), Myzus persicae
Nagaki, M.; Musashi, T.; Hirano, Y.; Tanaka, H.; Ichita, J.; Maki, Y.; Koyama, T.
Substrate specificities of farnesyl diphosphate synthases of Bacillus stearothermophilus and porcine liver with allylic substrate homologs having vinyl or ethynyl group
J. Mol. Catal. B
59
163-167
2009
Sus scrofa
-
Nagaki, M.; Nakada, M.; Musashi, T.; Kawakami, J.; Endo, T.; Maki, Y.; Koyama, T.
Substrate specificities of wild and mutated farnesyl diphosphate synthases: Reactivity of allylic substrate homologs having hydrophilic groups at omega-position
J. Mol. Catal. B
59
225-230
2009
Geobacillus stearothermophilus, Sus scrofa
-
Nagaki, M.; Kanno, H.; Musashi, T.; Shimizu, R.; Maki, Y.; Sagami, H.; Koyama, T.
Substrate specificities of farnesyl diphosphate synthases from Bacillus stearothermophilus and porcine liver with cyclic substrate homologs
J. Mol. Catal. B
60
186-190
2009
Geobacillus stearothermophilus, Sus scrofa
-
Gilg, A.B.; Tittiger, C.; Blomquist, G.J.
Unique animal prenyltransferase with monoterpene synthase activity
Naturwissenschaften
96
731-735
2009
Ips pini (Q58GE8), Ips pini
Chang, T.H.; Hsieh, F.L.; Ko, T.P.; Teng, K.H.; Liang, P.H.; Wang, A.H.
Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation
Plant Cell
22
454-467
2010
Mentha x piperita
Schmidt, A.; Waechtler, B.; Temp, U.; Krekling, T.; Seguin, A.; Gershenzon, J.
A bifunctional geranyl and geranylgeranyl diphosphate synthase is involved in terpene oleoresin formation in Picea abies
Plant Physiol.
152
639-655
2010
Picea abies (D2IT07), Picea abies
Mann, F.M.; Thomas, J.A.; Peters, R.J.
Rv0989c encodes a novel (E)-geranyl diphosphate synthase facilitating decaprenyl diphosphate biosynthesis in Mycobacterium tuberculosis
FEBS Lett.
585
549-554
2011
Mycobacterium tuberculosis, Mycobacterium tuberculosis CDC 1551
Nagegowda, D.
The small subunit of geranyl diphosphate synthase: A tool to improve aroma and flavour by metabolic engineering
J. Biosci.
35
167-169
2010
Antirrhinum majus, Clarkia breweri (Q6QLU5), Mentha x piperita (Q9SBR4)
Schmidt, A.; Nagel, R.; Krekling, T.; Christiansen, E.; Gershenzon, J.; Krokene, P.
Induction of isoprenyl diphosphate synthases, plant hormones and defense signalling genes correlates with traumatic resin duct formation in Norway spruce (Picea abies)
Plant Mol. Biol.
77
577-590
2011
Picea abies
Frick, S.; Nagel, R.; Schmidt, A.; Bodemann, R.R.; Rahfeld, P.; Pauls, G.; Brandt, W.; Gershenzon, J.; Boland, W.; Burse, A.
Metal ions control product specificity of isoprenyl diphosphate synthases in the insect terpenoid pathway
Proc. Natl. Acad. Sci. USA
110
4194-4199
2013
Phaedon cochleariae
Zhou, J.; Wang, X.; Kuang, M.; Wang, L.; Luo, H.; Mo, Y.; Wu, R.
Protonation-triggered carbon-chain elongation in geranyl pyrophosphate synthase (GPPS)
ACS Catal.
5
4466-4478
2015
Mentha x piperita (Q9SBR3 and Q9SBR4)
-
Pockrandt, D.; Li, S.M.
Geranylation of cyclic dipeptides by the dimethylallyl transferase AnaPT resulting in a shift of prenylation position on the indole ring
ChemBioChem
14
2023-2028
2013
Aspergillus fischeri
Heider, S.A.; Peters-Wendisch, P.; Beekwilder, J.; Wendisch, V.F.
IdsA is the major geranylgeranyl pyrophosphate synthase involved in carotenogenesis in Corynebacterium glutamicum
FEBS J.
281
4906-4920
2014
Corynebacterium glutamicum, Corynebacterium glutamicum ATCC 13032
Rivera-Perez, C.; Nyati, P.; Noriega, F.G.
A corpora allata farnesyl diphosphate synthase in mosquitoes displaying a metal ion dependent substrate specificity
Insect Biochem. Mol. Biol.
64
44-50
2015
Aedes aegypti (Q17F78)
Liu, Z.; Zhou, J.; Wu, R.; Xu, J.
Mechanism of assembling isoprenoid building blocks 1. elucidation of the structural motifs for substrate binding in geranyl pyrophosphate synthase
J. Chem. Theory Comput.
10
5057-5067
2014
Mentha x piperita (Q9SBR3 and Q9SBR4)
Rai, A.; Smita, S.S.; Singh, A.K.; Shanker, K.; Nagegowda, D.A.
Heteromeric and homomeric geranyl diphosphate synthases from Catharanthus roseus and their role in monoterpene indole alkaloid biosynthesis
Mol. Plant
6
1531-1549
2013
Catharanthus roseus (B2MV87), Catharanthus roseus
Liebhold, M.; Li, S.M.
Regiospecific benzylation of tryptophan and derivatives catalyzed by a fungal dimethylallyl transferase
Org. Lett.
15
5834-5837
2013
Aspergillus fumigatus
Xi, J.; Rossi, L.; Lin, X.; Xie, D.Y.
Overexpression of a synthetic insect-plant geranyl pyrophosphate synthase gene in Camelina sativa alters plant growth and terpene biosynthesis
Planta
244
215-230
2016
Myzus persicae
Keeling, C.I.; Chiu, C.C.; Aw, T.; Li, M.; Henderson, H.; Tittiger, C.; Weng, H.B.; Blomquist, G.J.; Bohlmann, J.
Frontalin pheromone biosynthesis in the mountain pine beetle, Dendroctonus ponderosae, and the role of isoprenyl diphosphate synthases
Proc. Natl. Acad. Sci. USA
110
18838-18843
2013
Dendroctonus ponderosae (I1VJ84), Dendroctonus ponderosae
Yang, L.; Jiang, L.; Li, W.; Yang, Y.; Zhang, G.; Luo, Y.
A homomeric geranyl diphosphate synthase-encoding gene from Camptotheca acuminata and its combinatorial optimization for production of geraniol in Escherichia coli
J. Ind. Microbiol. Biotechnol.
44
1431-1441
2017
Camptotheca acuminata (A0A2H4ULH9), Camptotheca acuminata
Rubat, S.; Varas, I.; Sepulveda, R.; Almonacid, D.; Gonzalez-Nilo, F.; Agosin, E.
Increasing the intracellular isoprenoid pool in Saccharomyces cerevisiae by structural fine-tuning of a bifunctional farnesyl diphosphate synthase
FEMS Yeast Res.
17
fox032
2017
Saccharomyces cerevisiae
Picard, M.E.; Nisole, A.; Beliveau, C.; Sen, S.; Barbar, A.; Shi, R.; Cusson, M.
Structural characterization of a lepidopteran type-II farnesyl diphosphate synthase from the spruce budworm, Choristoneura fumiferana Implications for inhibitor design
Insect Biochem. Mol. Biol.
92
84-92
2018
Choristoneura fumiferana (Q1XAB1)
Lee, J.S.; Pan, J.J.; Ramamoorthy, G.; Poulter, C.D.
Structure-function studies of Artemisia tridentata farnesyl diphosphate synthase and chrysanthemyl diphosphate synthase by site-directed mutagenesis and morphogenesis
J. Am. Chem. Soc.
139
14556-14567
2017
Artemisia spiciformis, Artemisia spiciformis (Q7XYS8)
Han, S.; Li, X.; Xia, Y.; Yu, Z.; Cai, N.; Malwal, S.R.; Han, X.; Oldfield, E.; Zhang, Y.
Farnesyl pyrophosphate synthase as a target for drug development discovery of natural-product-derived inhibitors and their activity in pancreatic cancer cells
J. Med. Chem.
62
10867-10896
2019
Homo sapiens (P14324)
Barja, M.V.; Rodriguez-Concepcion, M.
A Simple In vitro assay to measure the activity of geranylgeranyl diphosphate synthase and other short-chain prenyltransferases
Methods Mol. Biol.
2083
27-38
2020
Arabidopsis thaliana (P34802)
Park, J.; Zielinski, M.; Magder, A.; Tsantrizos, Y.S.; Berghuis, A.M.
Human farnesyl pyrophosphate synthase is allosterically inhibited by its own product
Nat. Commun.
8
14132
2017
Homo sapiens (P14324)
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