Information on EC 2.5.1.119 - beta-(isoxazolin-5-on-4-yl)-L-alanine synthase

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The expected taxonomic range for this enzyme is: Streptomyces platensis

EC NUMBER
COMMENTARY hide
2.5.1.119
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RECOMMENDED NAME
GeneOntology No.
beta-(isoxazolin-5-on-4-yl)-L-alanine synthase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
O-acetyl-L-serine + isoxazolin-5-one = 3-(5-oxoisoxazolin-4-yl)-L-alanine + acetate
show the reaction diagram
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SYSTEMATIC NAME
IUBMB Comments
O3-acetyl-L-serine:isoxazolin-5-one 4-(2-amino-2-carboxyethyl)transferase
3-(5-Oxoisoxazolin-4-yl)-L-alanine is an antifungal antibiotic produced by the bacterium Streptomyces platensis. The enzymes from the plants Lathyrus odoratus (sweet pea), L. sativus (grass pea) and Citrullus vulgaris (watermelon) that catalyse EC 2.5.1.118 (beta-(isoxazolin-5-on-2-yl)-L-alanine synthase) also catalyse this reaction in vitro, but not in vivo. Closely related and possibly identical to EC 2.5.1.47, cysteine synthase, and EC 2.5.1.51, beta-pyrazolylalanine synthase.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
O3-acetyl-L-serine + isoxazolin-5-one
3-(5-oxoisoxazolin-4-yl)-L-alanine + acetate
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
O3-acetyl-L-serine + isoxazolin-5-one
3-(5-oxoisoxazolin-4-yl)-L-alanine + acetate
show the reaction diagram
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE