Information on EC 2.5.1.24 - discadenine synthase

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The expected taxonomic range for this enzyme is: Dictyostelium

EC NUMBER
COMMENTARY hide
2.5.1.24
-
RECOMMENDED NAME
GeneOntology No.
discadenine synthase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + N6-(DELTA2-isopentenyl)-adenine = S-methyl-5'-thioadenosine + discadenine
show the reaction diagram
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
aminocarboxypropyl group transfer
-
-
-
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Zeatin biosynthesis
-
-
Biosynthesis of secondary metabolites
-
-
SYSTEMATIC NAME
IUBMB Comments
S-adenosyl-L-methionine:N6-(DELTA2-isopentenyl)-adenine 3-(3-amino-3-carboxypropyl)-transferase
-
CAS REGISTRY NUMBER
COMMENTARY hide
74082-52-3
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
no activity in Dictyostelium minutum
-
-
-
Manually annotated by BRENDA team
no activity in Polysphondylium pallidum
-
-
-
Manually annotated by BRENDA team
no activity in Polysphondylium violaceum
-
-
-
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
S-adenosyl-L-methionine + N6-(DELTA2-isopentenyl)-adenine
5'-methylthioadenosine + discadenine
show the reaction diagram
S-adenosylmethionine + N6-benzyladenine
3-(3-amino-3-carboxypropyl)-N6-benzyladenine + 5'-methylthioadenosine
show the reaction diagram
-
-
-
?
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
S-adenosyl-L-methionine + N6-(DELTA2-isopentenyl)-adenine
5'-methylthioadenosine + discadenine
show the reaction diagram
INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Mg2+
-
100 mM, 30% inhibition
Zn2+
-
100 mM, 80% inhibition
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0007
N6-benzyladenine
-
-
0.0185
S-adenosyl-L-methionine
-
-
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6 - 8.5
-
pH 6.0: about 55% of activity maximum, pH 8.5: about 60% of activity maximum
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
82000
-
gel filtration
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE