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Reference on EC 2.6.1.1 - aspartate transaminase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Potvin, C.; Simon, J.P.; Blanchard, M.H.
Thermal properties of NAD malate dehydrogenase and glutamate oxaloacetate transaminase in two genotypes of Arabidopsis thaliana (Cruciferae) from contrasting environments
Plant Sci. Lett.
31
35-47
1983
Arabidopsis thaliana
-
Manually annotated by BRENDA team
Mavrides, C.; Orr, W.
Multispecific aspartate and aromatic amino acid aminotransferases in Escherichia coli
J. Biol. Chem.
250
4128-4133
1975
Escherichia coli
Manually annotated by BRENDA team
Xing, R.; Whitman, W.B.
Characterization of amino acid aminotransferases of Methanococcus aeolicus
J. Bacteriol.
174
541-548
1974
Methanococcus aeolicus
Manually annotated by BRENDA team
Owen, T.G.; Hochachka, P.W.
Purification and properties of dolphin muscle aspartate and alanine transaminases and thier possible roles in the energy metabolism of diving mammals
Biochem. J.
143
541-553
1974
dolphin
Manually annotated by BRENDA team
Eze, L.C.; Echetebu, C.O.
Some properties of aspartate and alanine aminotransferases from Trichoderma virie
J. Gen. Microbiol.
120
523-527
1980
Trichoderma viride
-
Manually annotated by BRENDA team
Hatch, M.D.
Separation and properties of leaf aspartate aminotransferase and alanine aminotransferase isoenzymes operative in the C4 pathway of photosynthesis
Arch. Biochem. Biophys.
156
207-214
1973
Atriplex spongiosa
Manually annotated by BRENDA team
Blasco, J.; Puppo, J.
Effect of heavy metals (Cu, Cd and Pb) on aspartate and alanine aminotransferase in Ruditapes philippinarum (Mollusca: Bivalvia)
Comp. Biochem. Physiol. C
122
253-263
1999
Ruditapes philippinarum
Manually annotated by BRENDA team
Lowe, P.N.; Rowe, A.F.
Aspartate: 2-oxoglutarate aminotransferase from trichomonas vaginalis. Identity of aspartate aminotransferase and aromatic amino acid aminotransferase
Biochem. J.
232
689-695
1985
Trichomonas vaginalis, Trichomonas vaginalis Bushby
Manually annotated by BRENDA team
Yagi, T.; Kagamiyama, H.; Nozaki, M.; Soda, K.
Glutamate-aspartate transaminase from microorganisms
Methods Enzymol.
113
83-89
1985
Escherichia coli, Escherichia coli B / ATCC 11303
Manually annotated by BRENDA team
Ovchinnikov, Y.A.; Egorov, T.A.; Aldanova, N.A.; Feigina, M.Y.; Lipkin, V.M.; Abdulaev, N.G.; Grishin, E.V.; Kiselev, A.P.; Modyanov, M.N.; Braunstein, A.E.; Polyanovsky, O.L.; Nosikov, V.V.
The complete amino acid sequence of cytoplasmic aspartate aminotransferase from pig heart
FEBS Lett.
29
31-34
1973
Sus scrofa
Manually annotated by BRENDA team
Metzler, C.M.; Rogers, P.H.; Arone, A.; Martin, D.S.; Metzler, D.E.
Investigation of crystalline enzyme-substrate complexes of pyridoxal phosphate-dependent enzymes
Methods Enzymol.
62
551-558
1979
Sus scrofa
Manually annotated by BRENDA team
Yagi, T.; Sako, M.; Moriuti, S.; Shounaka, M.; Masaki, K.; Yamamoto, S.
Purification and characterization of aspartate aminotransferase isoenzymes from rice bran
Biosci. Biotechnol. Biochem.
57
2074-2080
1993
Oryza sativa
-
Manually annotated by BRENDA team
Yagi, T.; Masaki, K.; Yamamoto, S.
Distribution and cellular localization of aspartate aminotransferase isoenzymes in rice
Biosci. Biotechnol. Biochem.
57
2081-2084
1993
Oryza sativa
-
Manually annotated by BRENDA team
Muriana, F.J.G.; Alvarez-Ossorio, M.C.; Relimpio, A.M.
Further thermal characterization of an aspartate aminotransferase from a halophilic organism
Biochem. J.
298
465-470
1994
Haloferax mediterranei, Haloferax mediterranei R-4 / ATCC 33500
-
Manually annotated by BRENDA team
Mozzarelli, A.; Ottonello, S.; Rossi, G.L.; Fasellla, P.
Catalytic activity of aspartate aminotransferase in the crystal. Equilibrium and kinetic analysis
Eur. J. Biochem.
98
173-179
1979
Sus scrofa
Manually annotated by BRENDA team
Eichele, G.; Ford, G.C.; Jansonius, J.N.
Crystallization of pig mitochondrial aspartate aminotransferase by seeding with crystals of the chicken mitochondrial isoenzyme
J. Mol. Biol.
135
513-516
1979
Gallus gallus, Sus scrofa
Manually annotated by BRENDA team
Kamitori, S.; Hirotsu, K.; Higuchi, T.; Kondo, K.; Inoue, K.; Kuramitsu, S.; Kagamiyama, H.; Higuchi, Y.; Yasuoka, N.; Kusunoki, M.; Matsuura, Y.
Overproduction and preliminary X-ray characterization of aspartate aminotransferase from Escherichia coli
J. Biochem.
101
813-816
1987
Escherichia coli
Manually annotated by BRENDA team
Gehring, H.; Christen, P.; Eichele, G.; Glor, M.; Jansonius, J.N.; Reimer, A.S.; Smit, J.D.G.; Thaller, C.
Isolation, crystallization and preliminary crystallographic data of aspartate aminotransferase from chicken heart mitochondria
J. Mol. Biol.
115
97-101
1977
Gallus gallus
Manually annotated by BRENDA team
Arone, A.; Rogers, P.H.; Schmidt, J.; Han, C.N.; Harris, C.M.; Metzler, D.E.
Preliminary crystallographic study of aspartate: 2-oxoglutarate aminotransferase from pig heart
J. Mol. Biol.
112
509-513
1977
Sus scrofa
Manually annotated by BRENDA team
Yagi, T.; Toyosato, M.; Soda, K.
Crystalline aspartate aminotransferase from Pseudomonas striata
FEBS Lett.
61
34-37
1976
Pseudomonas putida, Pseudomonas putida IFO 12996
Manually annotated by BRENDA team
Kuramitsu, S.; Inoue, K.; Kondo, K.; Aki, K.; Kagamiyama, H.
Aspartate aminotransferase isozymes from rabbit liver. Purification and properties
J. Biochem.
97
1337-1345
1985
Oryctolagus cuniculus
Manually annotated by BRENDA team
Recasens, M.; Benezra, R.; Mandel, P.
Cysteine sulfinate aminotransferase and aspartate aminotransferase isoenzymes of rat brain. Purification, characterization, and further evidence for identity
Biochemistry
19
4583-4589
1980
Rattus norvegicus
Manually annotated by BRENDA team
Krista, M.L.; Fonda, M.L.
Beef brain cytoplasmic aspartate aminotransferase. Purification, kinetics, and physical properties
Biochim. Biophys. Acta
309
83-96
1973
Bos taurus
Manually annotated by BRENDA team
Barra, D.; Bossa, F.; Doonan, S.; Fahmy, H.M.A.; Hughes, G.J.; Martini, F.; Petruzzelli, R.; Wittmann-Liebold, B.
The cytosolic and mitochondrial aspartate aminotransferases from pig heart. A comparison of their primary structures, predicted secondary structures and some physical properties
Eur. J. Biochem.
108
405-414
1980
Sus scrofa
Manually annotated by BRENDA team
Ryan, E.; Bodley, F.; Fottrell, P.F.
Purification and characterization of aspartate aminotransferases from soybean root nodules and Rhizobium japonicum
Phytochemistry
11
957-963
1972
Bradyrhizobium japonicum, Glycine max, Bradyrhizobium japonicum 392
-
Manually annotated by BRENDA team
Romestant, M.; Jerebzoff, S.; Noaillac-Depeyre, J.; Gas, N.; Dargent, R.
Aspartate aminotransferase isoenzymes in Leptosphaeria michotii. Properties and intracellular location [published erratum appears in Eur J Biochem 1989 Jul 1;182(3):737]
Eur. J. Biochem.
180
153-159
1989
Leptosphaeria michotii
Manually annotated by BRENDA team
Capasso, S.; Garzillo, A.M.; Marino, G.; Mazzarella, L.; Pucci, P.; Sannia, G.
Mitochondrial bovine aspartate aminotransferase. Preliminary sequence and crystallographic data
FEBS Lett.
101
351-354
1979
Bos taurus
Manually annotated by BRENDA team
Numazawa, T.; Yamada, S.; Hase, T.; Sugiyama, T.
Aspartate aminotransferase from Panicum maximum Jacq. var. trichoglume Eyles, a C4 plant: purification, molecular properties, and preparation of antibody
Arch. Biochem. Biophys.
270
313-319
1989
Megathyrsus maximus
Manually annotated by BRENDA team
Orlacchio, A.; Campos-Cavieres, M.; Pashev, I.; Mun, E.A.
Some kinetic and other properties of the isoenzymes of aspartate aminotransferase isolated from sheep liver
Biochem. J.
177
583-593
1979
Ovis aries
Manually annotated by BRENDA team
Marino, G.; Nitti, G.; Arnone, M.I.; Sannia, G.; Gambacorta, A.; De Rosa, M.
Purification and characterization of aspartate aminotransferase from the thermoacidophilic archaebacterium Sulfolobus solfataricus
J. Biol. Chem.
263
12305-12309
1988
Saccharolobus solfataricus, Saccharolobus solfataricus (P14909)
Manually annotated by BRENDA team
Aoki, K.; Calva, E.; Fonseca, L.
Crystallization and immunological identification of dog heart aspartate aminotransferase isoenzymes
J. Biochem.
72
511-519
1972
Canis lupus familiaris
Manually annotated by BRENDA team
Izard, T.; Fol, B.; Paupit, R.A.; Jansonius, J.N.
Trigonal crystals of porcine mitochondrial aspartate aminotransferase
J. Mol. Biol.
215
341-344
1990
Sus scrofa
Manually annotated by BRENDA team
Malashkevich, V.N.; Sinitzina, N.I.
New crystal form of cytosolic chicken aspartate aminotransferase suitable for high-resolution X-ray analysis
J. Mol. Biol.
221
61-63
1991
Gallus gallus
Manually annotated by BRENDA team
Smith, D.L.; Almo, S.C.; Toney, M.D.; Ringe, D.
2.8-A-resolution crystal structure of an active-site mutant of aspartate aminotransferase from Escherichia coli
Biochemistry
28
8161-8167
1989
Escherichia coli
Manually annotated by BRENDA team
Herold, M.; Kirschner, K.
Reversible dissociation and unfolding of aspartate aminotransferase from Escherichia coli: characterization of a monomeric intermediate
Biochemistry
29
1907-1913
1990
Escherichia coli
Manually annotated by BRENDA team
Jger, J.; Khler, E.; Tucker, P.; Sauder, U.; Housley-Markovic, Z.; Fotheringham, I.; Edwards, M.; Hunter, M.; Kirschner, K.; Jansonius, J.N.
Crystallization and preliminary X-ray studies of an aspartate aminotransferase mutant from Escherichia coli
J. Mol. Biol.
209
499-501
1989
Escherichia coli
Manually annotated by BRENDA team
Fotheringham, I.; Dacey, S.; Taylor, P.; Smith, T.; Hunter, M.; Finlay, M.; Primrose, S.; Parker, D.; Edwards, M.
The cloning ans sequence analysis of the aspC and tyrB genes from Escherichia coli K12. Comparison of the primary structures of the aspartate aminotransferase and aromatic aminotransferase of E. coli with those of the pig aspartate aminotransferase isoenzymes
Biochem. J.
234
592-604
1986
Escherichia coli
-
Manually annotated by BRENDA team
Tanaka, T.; Yamamoto, S.; Taniguchi, M.; Hayashi, H.; Kuramitsu, S.; Kagamiyama, H.; Oi, S.
Further studies on aspartate aminotransferase of thermophilic methanogens by analysis of general properties, bound cofactors, and subunit structures
J. Biochem.
112
811-815
1992
Methanothermobacter thermautotrophicus, Methanothermobacter thermautotrophicus SF-4
Manually annotated by BRENDA team
Yagi, T.; Shounaka, M.; Yamamoto, S.
Distribution of aspartate aminotransferase activity in yeasts, and purification and characterization of mitochondrial and cytosolic isoenzymes from Rhodotorula minuta [corrected] [published erratum appears in J Biochem (Tokyo) 1990 Dec;108(6):1070]
J. Biochem.
107
151-159
1990
Cystobasidium minutum, Torulopsis candida
Manually annotated by BRENDA team
Taniguchi, M.; Sugiyama, T.
Aspartate aminotransferase from Eleusine coracana, a C4 plant: purification, characterization, and preparation of antibody
Arch. Biochem. Biophys.
282
427-432
1990
Eleusine coracana
Manually annotated by BRENDA team
Sung, M.H.; Tanizawa, K.; Tanaka, H.; Kuramitsu, S.; Kagamiyama, H.; Soda, K.
Purification and characterization of thermostable aspartate aminotransferase from a thermophilic Bacillus species
J. Bacteriol.
172
1345-1351
1990
Bacillus sp. (in: Bacteria), Bacillus sp. (in: Bacteria) YM-2
Manually annotated by BRENDA team
Barra, D.; Bossa, F.; Doonan, S.; Fahmy, H.M.A.; Martini, F.; Hughes, G.J.
Large-scale purification and some properties of the mitochondrial aspartate aminotransferase from pig heart
Eur. J. Biochem.
64
519-526
1976
Sus scrofa
Manually annotated by BRENDA team
Campos-Cavieres, M.; Munn, E.A.
Purification and some properties of cytoplasmic aspartate aminotransferase from sheep liver
Biochem. J.
135
683-693
1973
Ovis aries
Manually annotated by BRENDA team
Turano, F.J.; Wilson, B.J.; Matthews, B.F.
Rapid purification and thermostability of the cytoplasmic aspartate aminotransferase from carrot suspension cultures
Plant Physiol.
97
606-612
1991
Daucus carota
Manually annotated by BRENDA team
Yagi, T.; Kagamiyama, H.; Motosugi, K.; Nozaki, M.; Soda, K.
Crystallization and properties of aspartate aminotransferase from Escherichia coli B
FEBS Lett.
100
81-84
1979
Escherichia coli, Escherichia coli B / ATCC 11303
Manually annotated by BRENDA team
Quiroga, C.; Imperial, S.; Busquets, M.; Cortes, A.
Comparison of some of the properties of the holoenzymes and apoenzymes of the molecular forms of chicken liver cytoplasmic aspartate aminotransferase
Biochem. Soc. Trans.
19
74S
1991
Gallus gallus
Manually annotated by BRENDA team
Griffith, S.M.; Vance, C.P.
Aspartate aminotransferase in alfalfa root nodules. I. Purification and partial characterization
Plant Physiol.
90
1622-1629
1989
Medicago sativa
Manually annotated by BRENDA team
Lain-Guelbenzu, B.; Munoz-Blanco, J.; Cardenas, J.
Purification and properties of L-aspartate aminotransferase of Chlamydomonas reinhardtii
Eur. J. Biochem.
188
529-533
1990
Chlamydomonas reinhardtii, Chlamydomonas reinhardtii 6145c
Manually annotated by BRENDA team
Tanaka, T.; Tokuda, T.; Tachibana, A.; Taniguchi, M.; Oi, S.
Purification and some properties of aspartate aminotransferase of Methanobacterium thermoformicicum SF-4
Agric. Biol. Chem.
54
625-631
1990
Methanothermobacter thermautotrophicus, Methanothermobacter thermautotrophicus SF-4
-
Manually annotated by BRENDA team
Muriana, F.J.G.; Alvarez-Ossorio, M.C.; Relimpio, A.
Purification and characterization of aspartate aminotransferase from the halophile archaebacterium Haloferax mediterranei
Biochem. J.
278
149-154
1991
Haloferax mediterranei, Haloferax mediterranei R-4 / ATCC 33500
-
Manually annotated by BRENDA team
Reed, R.E.; Hess, J.L.
Partial purification and characterization of aspartate aminotransferases from seedling oat leaves
J. Biol. Chem.
250
4456-4461
1975
Avena sativa
Manually annotated by BRENDA team
Reynolds, P.H.S.; Boland, M.J.; Farnden, K.J.F.
Enzymes of nitrogen metabolism in legume nodules: partial purification and properties of the aspartate aminotransferases from lupine nodules
Arch. Biochem. Biophys.
209
524-533
1981
Lupinus angustifolius
Manually annotated by BRENDA team
Yagi, T.; Kagamiyama, H.; Nozaki, M.
Aspartate: 2-oxoglutarate aminotransferase from bakers yeast: crystallization and characterization
J. Biochem.
92
35-43
1982
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Shrawder, E.J.; Martinez-Carrion, M.
Simultaneous isolation and characterization of chicken supernatant and mitochondrial isoenzymes of aspartate transaminase
J. Biol. Chem.
248
2140-2146
1973
Gallus gallus
Manually annotated by BRENDA team
Zhou, S.L.; Stump, D.; Kiang, C.L.; Isola, L.M.; Berk, P.D.
Mitochondrial aspartate aminotransferase expressed on the surface of 3T3-L1 adipocytes mediates saturable fatty acid uptake
Proc. Soc. Exp. Biol. Med.
208
263-270
1995
Rattus norvegicus
Manually annotated by BRENDA team
Taniguchi, M.; Kobe, A.; Kato, M.; Sugiyama, T.
Aspartate aminotransferase isozymes in Panicum miliaceum L., an NAD-malic enzyme-type C4 plant: comparison of enzymatic properties primary structures, and expression patterns
Arch. Biochem. Biophys.
318
295-306
1995
Panicum miliaceum
Manually annotated by BRENDA team
Okada, M.; Ayabe, Y.
Effects of aminoguanidine and pyridoxal phosphate on glycation reaction of aspartate aminotransferase and serum albumin
J. Nutr. Sci. Vitaminol.
41
43-50
1995
Rattus norvegicus
Manually annotated by BRENDA team
Vessal, M.; Taher, M.
Partial purification and kinetic properties of human placental cytosolic aspartate transaminase
Comp. Biochem. Physiol. B
110
431-437
1995
Homo sapiens
Manually annotated by BRENDA team
Hayashi, H.; Kagamiyama, H.
Reaction of aspartate aminotransferase with L-erythro-3-hydroxyaspartate: involvement of Tyr70 in stabilization of the catalytic intermediates
Biochemistry
34
9413-9423
1995
Escherichia coli
Manually annotated by BRENDA team
Okamoto, A.; Kato, R.; Masui, R.; Yamagishi, A.; Oshima, T.; Kuramitsu, S.
An aspartate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus HB8
J. Biochem.
119
135-144
1996
Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579
Manually annotated by BRENDA team
Kato, Y.; Asano, Y.; Makar, T.K.; Cooper, A.J.
Irreversible inactivation of aspartate aminotransferase by 2-oxoglutaconic acid and its dimethyl ester
J. Biochem.
120
531-539
1996
Mus musculus, Rattus norvegicus, Sus scrofa
Manually annotated by BRENDA team
Nobe, Y.; Kawaguchi, S.; Ura, H.; Nakai, T.; Hirotsu, K.; Kato, R.; Kuramitsu, S.
The novel substrate recognition mechanism utilized by aspartate aminotransferase of the extreme thermophile Thermus thermophilus HB8
J. Biol. Chem.
273
29554-29564
1998
Escherichia coli, Thermus thermophilus (Q56232), Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579 (Q56232)
Manually annotated by BRENDA team
Kim, H.; Ikegami, K.; Nakaoka, M.; Yagi, M.; Shibata, H.; Sawa, Y.
Characterization of aspartate aminotransferase from the cyanobacterium Phormidium lapideum
Biosci. Biotechnol. Biochem.
67
490-498
2003
Phormidium lapideum
Manually annotated by BRENDA team
Azzariti, A.; Vacca, R.A.; Giannattasio, S.; Merafina, R.S.; Marra, E.; Doonan, S.
Kinetic properties and thermal stabilities of mutant forms of mitochondrial aspartate aminotransferase
Biochim. Biophys. Acta
1386
29-38
1998
Gallus gallus
Manually annotated by BRENDA team
Wilkie, S.E.; Warren, M.J.
Recombinant expression, purification, and characterization of three isoenzymes of aspartate aminotransferase from Arabidopsis thaliana
Protein Expr. Purif.
12
381-389
1998
Arabidopsis thaliana
Manually annotated by BRENDA team
Petrovic, S.; Semencic, L.; Ozretic, B.; Krajnovic-Ozretic, M.
Selective determination of fish aspartate aminotransferase isoenzymes by their differential sensitivity to proteases
Comp. Biochem. Physiol. B
124
209-214
1999
Chelon auratus
Manually annotated by BRENDA team
Birolo, L.; Malashkevich, V.N.; Capitani, G.; De Luca, F.; Moretta, A.; Jansonius, J.N.; Marino, G.
Functional and structural analysis of cis-proline mutants of Escherichia coli aspartate aminotransferase
Biochemistry
38
905-913
1999
Escherichia coli (P00509)
Manually annotated by BRENDA team
Mattingly, J.R., Jr.; Yanez, A.J.; Martinez-Carrion, M.
The folding of nascent mitochondrial aspartate aminotransferase synthesized in a cell-free extract can be assisted by GroEL and GroES
Arch. Biochem. Biophys.
382
113-122
2000
Rattus norvegicus
Manually annotated by BRENDA team
Birolo, L.; Tutino, M.L.; Fontanella, B.; Gerday, C.; Mainolfi, K.; Pascarella, S.; Sannia, G.; Vinci, F.; Marino, G.
Aspartate aminotransferase from the Antarctic bacterium Pseudoalteromonas haloplanktis TAC 125. Cloning, expression, properties, and molecular modelling
Eur. J. Biochem.
267
2790-2802
2000
Pseudoalteromonas haloplanktis, Pseudoalteromonas haloplanktis TAC 125
Manually annotated by BRENDA team
Martins, L.L.; Mourato, M.P.; de Varennes, A.
Effects of substrate structural analogues on the enzymatic activities of aspartate aminotransferase isoenzymes
J. Enzyme Inhib.
16
251-257
2001
Lupinus albus
Manually annotated by BRENDA team
Mohamed, T.M.
Purification and characterization of aspartate aminotransferase from developing embryos of the camel tick Hyalomma dromedarii
Exp. Appl. Acarol.
25
231-244
2001
Hyalomma dromedarii
Manually annotated by BRENDA team
Deu, E.; Koch, K.A.; Kirsch, J.F.
The role of the conserved Lys68*:Glu265 intersubunit salt bridge in aspartate aminotransferase kinetics: multiple forced covariant amino acid substitutions in natural variants
Protein Sci.
11
1062-1073
2002
Escherichia coli
Manually annotated by BRENDA team
Martins, M.L.; Mourato, M.P.; de Varennes e Mendonca, A.P.
Characterization of aspartate aminotransferase isoenzymes from leaves of Lupinus albus L. cv Estoril
J. Biochem. Mol. Biol.
35
220-227
2002
Lupinus albus
Manually annotated by BRENDA team
Artigues, A.; Crawford, D.L.; Iriarte, A.; Martinez-Carrion, M.
Divergent Hsc70 binding properties of mitochondrial and cytosolic aspartate aminotransferase. Implications for their segregation to different cellular compartments
J. Biol. Chem.
273
33130-33134
1998
Rattus norvegicus, Rattus norvegicus (P00507)
Manually annotated by BRENDA team
Chow, M.A.; McElroy, K.E.; Corbett, K.D.; Berger, J.M.; Kirsch, J.F.
Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase
Biochemistry
43
12780-12787
2004
Escherichia coli (P00509)
Manually annotated by BRENDA team
Islam, M.M.; Goto, M.; Miyahara, I.; Ikushiro, H.; Hirotsu, K.; Hayashi, H.
Binding of C5-dicarboxylic substrate to aspartate aminotransferase: implications for the conformational change at the transaldimination step
Biochemistry
44
8218-8229
2005
Escherichia coli (P00509)
Manually annotated by BRENDA team
Kochkina, V.M.
Isolation, purification, and crystallization of aspartate aminotransferase from wheat grain
Biochemistry
69
897-900
2004
Triticum aestivum
Manually annotated by BRENDA team
Hayashi, H.; Mizuguchi, H.; Miyahara, I.; Islam, M.M.; Ikushiro, H.; Nakajima, Y.; Hirotsu, K.; Kagamiyama, H.
Strain and catalysis in aspartate aminotransferase
Biochim. Biophys. Acta
1647
103-109
2003
Escherichia coli
Manually annotated by BRENDA team
Lo, H.H.; Hsu, S.K.; Lin, W.D.; Chan, N.L.; Hsu, W.H.
Asymmetrical synthesis of L-homophenylalanine using engineered Escherichia coli aspartate aminotransferase
Biotechnol. Prog.
21
411-415
2005
Escherichia coli
Manually annotated by BRENDA team
Islam, M.M.; Hayashi, H.; Kagamiyama, H.
Reaction of aspartate aminotransferase with C5-dicarboxylic acids: comparison with the reaction with C4-dicarboxylic acids
J. Biochem.
134
277-285
2003
Escherichia coli
Manually annotated by BRENDA team
Oses-Prieto, J.A.; Bengoechea-Alonso, M.T.; Artigues, A.; Iriarte, A.; Martinez-Carrion, M.
The nature of the rate-limiting steps in the refolding of the cofactor-dependent protein aspartate aminotransferase
J. Biol. Chem.
278
49988-49999
2003
Rattus norvegicus
Manually annotated by BRENDA team
Hayashi, H.; Mizuguchi, H.; Miyahara, I.; Nakajima, Y.; Hirotsu, K.; Kagamiyama, H.
Conformational change in aspartate aminotransferase on substrate binding induces strain in the catalytic group and enhances catalysis
J. Biol. Chem.
278
9481-9488
2003
Escherichia coli (P00509)
Manually annotated by BRENDA team
Kwok, E.Y.; Hanson, M.R.
GFP-labelled Rubisco and aspartate aminotransferase are present in plastid stromules and traffic between plastids
J. Exp. Bot.
55
595-604
2004
Arabidopsis thaliana
Manually annotated by BRENDA team
Bousova, I.; Bakala, H.; Chudacek, R.; Palicka, V.; Drsata, J.
Glycation-induced inactivation of aspartate aminotransferase, effect of uric acid
Mol. Cell. Biochem.
278
85-92
2005
Sus scrofa
Manually annotated by BRENDA team
Shanti, N.D.; Shashikumar, K.C.; Desai, P.V.
Influence of proline on rat brain activities of alanine aminotransferase, aspartate aminotransferase and acid phosphatase
Neurochem. Res.
29
2197-2206
2004
Rattus norvegicus
Manually annotated by BRENDA team
Adams, B.; Lowpetch, K.; Thorndycroft, F.; Whyte, S.M.; Young, D.W.
Stereochemistry of reactions of the inhibitor/substrates L- and D-beta-chloroalanine with beta-mercaptoethanol catalysed by L-aspartate aminotransferase and D-amino acid aminotransferase respectively
Org. Biomol. Chem.
3
3357-3364
2005
Escherichia coli, Escherichia coli TY103
Manually annotated by BRENDA team
Ktasura, Y.; Shirouzu, M.; Yamaguchi, H.; Ishitani, R.; Nureki, O.; Kuramitsu, S.; Hayashi, H.; Yokoyama, S.
Crystal structure of a putative aspartate aminotransferase belonging to subgroup IV
Proteins Struct. Funct. Bioinform.
55
487-492
2004
Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579
Manually annotated by BRENDA team
Samsonova, M.V.; Min'kova, N.O.; Lapteva, T.I.; Mikodina, E.V.; Filippovich, Y.B.
Aspartate and alanine aminotransferases in early development of the keta
Russ. J. Dev. Biol.
34
14-18
2003
Oncorhynchus keta
-
Manually annotated by BRENDA team
Seetharamappa, J.; Oke, M.; Liu, H.; McMahon, S.A.; Johnson, K.A.; Carter, L.; Dorward, M.; Zawadzki, M.; Overton, I.M.; van Niekirk, C.A.; Graham, S.; Botting, C.H.; Taylor, G.L.; White, M.F.; Barton, G.J.; Coote, P.J.; Naismith, J.H.
Expression, purification, crystallization, data collection and preliminary biochemical characterization of methicillin-resistant Staphylococcus aureus Sar2028, an aspartate/tyrosine/phenylalanine pyridoxal-5-phosphate-dependent aminotransferase
Acta Crystallogr. Sect. F
F63
452-456
2007
Staphylococcus aureus
Manually annotated by BRENDA team
Petlevski, R.; Hadzija, M.; Bajalo, J.L.; Juretic, D.
Effect of acarbose on alanine aminotransferase and aspartate aminotransferase activities in the liver of control and diabetic CBA mice
Acta Pharm.
56
87-93
2006
Mus musculus
Manually annotated by BRENDA team
Artigues, A.; Iriarte, A.; Martinez-Carrion, M.
Identification of Hsc70 binding sites in mitochondrial aspartate aminotransferase
Arch. Biochem. Biophys.
450
30-38
2006
Rattus norvegicus
Manually annotated by BRENDA team
Wang, N.C.; Lee, C.Y.
Enhanced transaminase activity of a bifunctional L-aspartate 4-decarboxylase
Biochem. Biophys. Res. Commun.
356
368-373
2007
Escherichia coli (P00509)
Manually annotated by BRENDA team
Deu, E.; Kirsch, J.F.
The unfolding pathway for Apo Escherichia coli aspartate aminotransferase is dependent on the choice of denaturant
Biochemistry
46
5810-5818
2007
Escherichia coli (P00509)
Manually annotated by BRENDA team
Deu, E.; Kirsch, J.F.
Cofactor-directed reversible denaturation pathways: the cofactor-stabilized Escherichia coli aspartate aminotransferase homodimer unfolds through a pathway that differs from that of the apoenzyme
Biochemistry
46
5819-5829
2007
Escherichia coli
Manually annotated by BRENDA team
Rakhmanova, T.I.; Popova, T.N.
Regulation of 2-oxoglutarate metabolism in rat liver by NADP-isocitrate dehydrogenase and aspartate aminotransferase
Biochemistry
71
211-217
2006
Rattus norvegicus
Manually annotated by BRENDA team
Rakhmanova, T.I.; Popova, T.N.; Semenikhina, A.V.
Subcellular localization, purification, and some catalytic properties of aspartate aminotransferase from Spirodela polyrhiza
Biol. Bull.
33
347-352
2006
Spirodela polyrhiza, Spirodela polyrhiza SJ
-
Manually annotated by BRENDA team
Ohgami, N.; Upadhyay, S.; Kabata, A.; Morimoto, K.; Kusakabe, H.; Suzuki, H.
Determination of the activities of glutamic oxaloacetic transaminase and glutamic pyruvic transaminase in a microfluidic system
Biosens. Bioelectron.
22
1330-1336
2007
Sus scrofa
Manually annotated by BRENDA team
Totan, A.; Greabu, M.; Totan, C.; Spinu, T.
Salivary aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase: possible markers in periodontal diseases?
Clin. Chem. Lab. Med.
44
612-615
2006
Homo sapiens
Manually annotated by BRENDA team
Boutet, I.; Meistertzheim, A.L.; Tanguy, A.; Thebault, M.T.; Moraga, D.
Molecular characterization and expression of the gene encoding aspartate aminotransferase from the Pacific oyster Crassostrea gigas exposed to environmental stressors
Comp. Biochem. Physiol. C
140
69-78
2005
Crassostrea gigas (Q4LDF8), Crassostrea gigas
Manually annotated by BRENDA team
Paknejad, M.; Emtiaz, S.; Khoobyari, M.M.; Gharb, M.T.; Yazdi, M.T.
Analysis of aspartate aminotransferase and alkaline phosphatase in crevicular fluid from implants with and without peri-implantitis
Implant Dent.
15
62-69
2006
Homo sapiens
Manually annotated by BRENDA team
Harenberg, J.; Joerg, I.; Weiss, C.
Observations of alanine aminotransferase and aspartate aminotransferase in THRIVE studies treated orally with ximelagatran
Int. J. Toxicol.
25
165-169
2006
Homo sapiens
Manually annotated by BRENDA team
Tordjman, J.; Leroyer, S.; Chauvet, G.; Quette, J.; Chauvet, C.; Tomkiewicz, C.; Chapron, C.; Barouki, R.; Forest, C.; Aggerbeck, M.; Antoine, B.
Cytosolic aspartate aminotransferase: A new partner in adipocyte glyceroneogenesis and an atypical target of thiazolidinedione
J. Biol. Chem.
282
23591-23602
2007
Homo sapiens
Manually annotated by BRENDA team
Guidetti, P.; Amori, L.; Sapko, M.T.; Okuno, E.; Schwarcz, R.
Mitochondrial aspartate aminotransferase: a third kynurenate-producing enzyme in the mammalian brain
J. Neurochem.
102
103-111
2007
Homo sapiens, Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
McKenna, M.C.; Hopkins, I.B.; Lindauer, S.L.; Bamford, P.
Aspartate aminotransferase in synaptic and nonsynaptic mitochondria: differential effect of compounds that influence transient hetero-enzyme complex (metabolon) formation
Neurochem. Int.
48
629-636
2006
Rattus norvegicus
Manually annotated by BRENDA team
de la Torre, F.; De Santis, L.; Suarez, M.F.; Crespillo, R.; Canovas, F.M.
Identification and functional analysis of a prokaryotic-type aspartate aminotransferase: implications for plant amino acid metabolism
Plant J.
46
414-425
2006
Arabidopsis thaliana (Q9SIE1), Oryza sativa, Pinus pinaster (Q5F4K8)
Manually annotated by BRENDA team
de la Torre, F.; Suarez, M.F.; Santis, L.; Canovas, F.M.
The aspartate aminotransferase family in conifers: biochemical analysis of a prokaryotic-type enzyme from maritime pine
Tree Physiol.
27
1283-1291
2007
Pinus pinaster
Manually annotated by BRENDA team
Chang, M.L.; Yang, C.W.; Chen, J.C.; Ho, Y.P.; Pan, M.J.; Lin, C.H.; Lin, D.Y.
Disproportional exaggerated aspartate transaminase is a useful prognostic parameter in late leptospirosis
World J. Gastroenterol.
11
5553-5556
2005
Homo sapiens
Manually annotated by BRENDA team
Khedmat, H.; Fallahian, F.; Abolghasemi, H.; Hajibeigi, B.; Attarchi, Z.; Alaeddini, F.; Holisaz, M.T.; Pourali, M.; Sharifi, S.; Zarei, N.
Serum gamma-glutamyltransferase, alanine aminotransferase, and aspartate aminotransferase activity in Iranian healthy blood donor men
World J. Gastroenterol.
13
889-894
2007
Homo sapiens
Manually annotated by BRENDA team
Birolo, L.; Arnone, M.I.; Cubellis, M.V.; Andreotti, G.; Nitti, G.; Marino, G.; Sannia, G.
The active site of Sulfolobus solfataricus aspartate aminotransferase.
Biochim. Biophys. Acta
1080
198-204
1991
Saccharolobus solfataricus (P14909)
Manually annotated by BRENDA team
Cubellis, M.V.; Rozzo, C.; Nitti, G.; Arnone, M.I.; Marino, G.; Sannia, G.
Cloning and sequencing of the gene coding for aspartate aminotransferase from the thermoacidophilic archaebacterium Sulfolobus solfataricus.
Eur. J. Biochem.
186
375-381
1989
Saccharolobus solfataricus (Q9UWM3), Saccharolobus solfataricus, Saccharolobus solfataricus MT4 (Q9UWM3)
Manually annotated by BRENDA team
Arnone, M.I.; Birolo, L.; Giamberini, M.; Cubellis, M.V.; Nitti, G.; Sannia, G.; Marino, G.
Limited proteolysis as a probe of conformational changes in aspartate aminotransferase from Sulfolobus solfataricus.
Eur. J. Biochem.
204
1183-1189
1992
Saccharolobus solfataricus (P14909), Saccharolobus solfataricus
Manually annotated by BRENDA team
Zappacosta, F.; Sannia, G.; Savoy, L.A.; Marino, G.; Pucci, P.
Post-translational modifications in aspartate aminotransferase from Sulfolobus solfataricus. Detection of N-epsilon-methyllysines by mass spectrometry.
Eur. J. Biochem.
222
761-767
1994
Saccharolobus solfataricus (P14909)
Manually annotated by BRENDA team
Arnone, M.I.; Birolo, L.; Pascarella, S.; Cubellis, M.V.; Bossa, F.; Sannia, G.; Marino, G.
Stability of aspartate aminotransferase from Sulfolobus solfataricus.
Protein Eng.
10
237-248
1997
Saccharolobus solfataricus, Saccharolobus solfataricus (P14909)
Manually annotated by BRENDA team
Marciano, D.; Llorente, C.; Maugeri, D.A.; de la Fuente, C.; Opperdoes, F.; Cazzulo, J.J.; Nowicki, C.
Biochemical characterization of stage-specific isoforms of aspartate aminotransferases from Trypanosoma cruzi and Trypanosoma brucei
Mol. Biochem. Parasitol.
161
12-20
2008
Trypanosoma cruzi (Q4D080), Trypanosoma cruzi (Q4D1Q4), Trypanosoma cruzi, Trypanosoma brucei (Q964F0), Trypanosoma brucei (Q964F1), Trypanosoma brucei
Manually annotated by BRENDA team
Swingley, W.D.; Sadekar, S.; Mastrian, S.D.; Matthies, H.J.; Hao J.; Ramos, H.; Acharya, C.R.; Conrad, A.L.; Taylor, H.L.; Dejesa, L.C.; Shah, M.K.; O'huallachain, M.E.; Lince, M.T.; Blankenship, R.E.; Beatty, J.T.; Touchman, J.W.
The complete genome sequence of Roseobacter denitrificans reveals a mixotrophic rather than photosynthetic metabolism
J. Bacteriol.
189
683-690
2007
Roseobacter denitrificans OCh 114
Manually annotated by BRENDA team
Artun, B.; Kueskue-Kiraz, Z.; Gulluoglu, M.; Cevikbas, U.; Kocak-Toker, N.; Uysal, M.
The effect of carnosine pretreatment on oxidative stress and hepatotoxicity in binge ethanol administered rats
Hum. Exp. Toxicol.
29
659-665
2010
Rattus norvegicus
Manually annotated by BRENDA team
Bourdelas, A.; Li, H.Y.; Carron, C.; Shi, D.L.
Dynamic expression pattern of distinct genes in the presomitic and somitic mesoderm during Xenopus development
Int. J. Dev. Biol.
53
1075-1079
2009
Xenopus laevis (Q7ZTK9)
Manually annotated by BRENDA team
Fernandez-Real, J.M.; Ortega, F.; Gomez-Ambrosi, J.; Salvador, J.; Fruehbeck, G.; Ricart, W.
Circulating osteocalcin concentrations are associated with parameters of liver fat infiltration and increase in parallel to decreased liver enzymes after weight loss
Osteoporos. Int.
21
2101-2107
2010
Mus musculus
Manually annotated by BRENDA team
Katayama, R.; Nagata, S.; Iida, H.; Yamagishi, N.; Yamashita, T.; Furuhama, K.
Possible role of cysteine-S-conjugate beta-lyase in species differences in cisplatin nephrotoxicity
Food Chem. Toxicol.
49
2053-2059
2011
Oryctolagus cuniculus, Mus musculus, Rattus norvegicus (P00507)
Manually annotated by BRENDA team
Mayer, J.; Denger, K.; Hollemeyer, K.; Schleheck, D.; Cook, A.M.
(R)-Cysteate-nitrogen assimilation by Cupriavidus necator H16 with excretion of 3-sulfolactate: a patchwork pathway
Arch. Microbiol.
194
949-957
2012
Cupriavidus necator, Cupriavidus necator H16 / ATCC 23440 / NCIB 10442 / S-10-1
Manually annotated by BRENDA team
Jain, R.; Jordanova, R.; Mueller, I.B.; Wrenger, C.; Groves, M.R.
Purification, crystallization and preliminary X-ray analysis of the aspartate aminotransferase of Plasmodium falciparum
Acta Crystallogr. Sect. F
66
409-412
2010
Plasmodium falciparum
Manually annotated by BRENDA team
Sundareswaran, V.R.; Singh, A.K.; Dube, S.; Shivaji, S.
Aspartate aminotransferase is involved in cold adaptation in psychrophilic Pseudomonas syringae
Arch. Microbiol.
192
663-672
2010
Pseudomonas syringae
Manually annotated by BRENDA team
Crdenas-Fernandez, M.; Lopez, C.; Alvaro, G.; Lopez-Santn, J.
L-Phenylalanine synthesis catalyzed by immobilized aspartate aminotransferase
Biochem. Eng. J.
63
15-21
2012
Sus scrofa
-
Manually annotated by BRENDA team
Liu, D.; Pozharski, E.; Fu, M.; Silverman, R.B.; Ringe, D.
Mechanism of inactivation of Escherichia coli aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-furancarboxylic acid
Biochemistry
49
10507-10515
2010
Escherichia coli (D3H0F7), Escherichia coli
Manually annotated by BRENDA team
Griswold, W.R.; Fisher, A.J.; Toney, M.D.
Crystal structures of aspartate aminotransferase reconstituted with 1-deazapyridoxal 5-phosphate: internal aldimine and stable L-aspartate external aldimine
Biochemistry
50
5918-5924
2011
Escherichia coli (P00509)
Manually annotated by BRENDA team
Fernandez, F.J.; de Vries, D.; Pena-Soler, E.; Coll, M.; Christen, P.; Gehring, H.; Vega, M.C.
Structure and mechanism of a cysteine sulfinate desulfinase engineered on the aspartate aminotransferase scaffold
Biochim. Biophys. Acta
1824
339-349
2012
Escherichia coli (P00509)
Manually annotated by BRENDA team
Nadeem, M.; Rashid, N.; Iqbal, M.; Gardner, Q.; Akhtar, M.
First cloning and characterization of aspartate aminotransferase from river buffalo (Bubalus bubalis)
Biologia
66
1202-1210
2011
Bubalus bubalis
-
Manually annotated by BRENDA team
Wu, H.J.; Yang, Y.; Wang, S.; Qiao, J.Q.; Xia, Y.F.; Wang, Y.; Wang, W.D.; Gao, S.F.; Liu, J.; Xue, P.Q.; Gao, X.W.
Cloning, expression and characterization of a new aspartate aminotransferase from Bacillus subtilis B3
FEBS J.
278
1345-1357
2011
Bacillus subtilis (Q939C9)
Manually annotated by BRENDA team
Wrenger, C.; Mueller, I.B.; Schifferdecker, A.J.; Jain, R.; Jordanova, R.; Groves, M.R.
Specific inhibition of the aspartate aminotransferase of Plasmodium falciparum
J. Mol. Biol.
405
956-971
2011
Plasmodium falciparum (O96142), Plasmodium falciparum
Manually annotated by BRENDA team
Arnone, M.I.; Birolo, L.; Cubellis, M.V.; Nitti, G.; Marino, G.; Sannia, G.
Expression of a hyperthermophilic aspartate aminotransferase in Escherichia coli
Biochim. Biophys. Acta
1160
206-212
1992
Saccharolobus solfataricus, Saccharolobus solfataricus MT-4 / DSM 5833
Manually annotated by BRENDA team
Cubellis, M.V.; Arnone, M.I.; Birolo, L.; Sannia, G.; Marino, G.
Comparative studies on thermophilicity and thermostability of aspartate aminotransferases
Biotechnol. Appl. Biochem.
18
417-425
1993
Saccharolobus solfataricus
Manually annotated by BRENDA team
Donini, S.; Ferrari, M.; Fedeli, C.; Faini, M.; Lamberto, I.; Marletta, A.S.; Mellini, L.; Panini, M.; Percudani, R.; Pollegioni, L.; Caldinelli, L.; Petrucco, S.; Peracchi, A.
Recombinant production of eight human cytosolic aminotransferases and assessment of their potential involvement in glyoxylate metabolism
Biochem. J.
422
265-272
2009
Homo sapiens (Q8NHS2)
Manually annotated by BRENDA team
Saroj, D.; Singh, K.; Anant, A.; Biswal, B.
Overexpression, purification, crystallization and structure determination of AspB, a putative aspartate aminotransferase from Mycobacterium tuberculosis
Acta Crystallogr. Sect. F
70
928-932
2014
Mycobacterium tuberculosis (P96847), Mycobacterium tuberculosis H37Rv (P96847)
Manually annotated by BRENDA team
Abendroth, J.; Choi, R.; Wall, A.; Clifton, M.C.; Lukacs, C.M.; Staker, B.L.; Van Voorhis, W.; Myler, P.; Lorimer, D.D.; Edwards, T.E.
Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia
Acta crystallogr. Sect. F
71
566-571
2015
Giardia intestinalis (A8B1V5), Trypanosoma brucei brucei (Q385Q9), Leishmania major (Q4FX34), Trypanosoma brucei brucei 927 / 4 GUTat10.1 / TREU927 (Q385Q9), Giardia intestinalis ATCC 50803 (A8B1V5)
Manually annotated by BRENDA team
Yang, Y.
Enhancing doxorubicin efficacy through inhibition of aspartate transaminase in triple-negative breast cancer cells
Biochem. Biophys. Res. Commun.
473
1295-1300
2016
Homo sapiens (P17174), Homo sapiens
Manually annotated by BRENDA team
Jiang, X.; Wang, J.; Chang, H.; Zhou, Y.
Recombinant expression, purification and crystallographic studies of the mature form of human mitochondrial aspartate aminotransferase
Biosci. Trends
10
79-84
2016
Homo sapiens (P00505)
Manually annotated by BRENDA team
Maciaga, M.; Szkop, M.; Paszkowski, A.
Biochemical characterization of aspartate aminotransferase allozymes from common wheat
Cent. Eur. J. Biol.
8
1183-1193
2013
Triticum aestivum (B0FRH4), Triticum aestivum (B5B1F8)
-
Manually annotated by BRENDA team
Wang, R.; Zhang, M.; Liu, H.; Xu, J.; Yu, J.; He, F.; Zhang, X.; Dong, S.; Dou, D.
PsAAT3, an oomycete-specific aspartate aminotransferase, is required for full pathogenicity of the oomycete pathogen Phytophthora sojae
Fungal Biol.
120
620-630
2016
Phytophthora sojae, Phytophthora sojae P6497
Manually annotated by BRENDA team
Graindorge, M.; Giustini, C.; Kraut, A.; Moyet, L.; Curien, G.; Matringe, M.
Three different classes of aminotransferases evolved prephenate aminotransferase functionality in arogenate-competent microorganisms
J. Biol. Chem.
289
3198-3208
2014
Sinorhizobium meliloti (Q02635)
Manually annotated by BRENDA team
Luo, C.; Lin, Q.; Lin, S.; Meng, C.; Wang, H.
Cosynthesis of l-homophenylalanine and 2-phenylethanol by recombinant Saccharomyces cerevisiae expressing aspartate aminotransferase from Escherichia coli BL21(DE3)
J. Biosci. Bioeng.
123
1-7
2017
Escherichia coli (A0A140ND68), Escherichia coli BL21-DE3 (A0A140ND68)
Manually annotated by BRENDA team
Zou, L.; Zhao, H.; Wang, D.; Wang, M.; Zhang, C.; Xiao, F.
Expression and purification of a functional recombinant aspartate aminotransferase (AST) from Escherichia coli
J. Microbiol. Biotechnol.
24
998-1003
2014
Homo sapiens (P00505)
Manually annotated by BRENDA team
Xu, J.; Zhang, J.; Guo, Y.; Zhang, W.
Genetically modifying aspartate aminotransferase and aspartate ammonia-lyase affects metabolite accumulation in L-lysine producing strain derived from Corynebacterium glutamicum ATCC13032
J. Mol. Catal. B
113
82-89
2015
Corynebacterium glutamicum, Corynebacterium glutamicum ATCC 13032
-
Manually annotated by BRENDA team
Xu, X.; Gu, L.; He, P.; Zhou, R.
Characterization of five putative aspartate aminotransferase genes in the N2-fixing heterocystous cyanobacterium Anabaena sp. strain PCC 7120
Microbiology
161
1219-1230
2015
Nostoc sp. (Q8YMS6), Nostoc sp. (Q8YTF2), Nostoc sp. (Q8YUK5), Nostoc sp. (Q8YY14), Nostoc sp. PCC 7120 (Q8YMS6), Nostoc sp. PCC 7120 (Q8YTF2), Nostoc sp. PCC 7120 (Q8YUK5), Nostoc sp. PCC 7120 (Q8YY14)
Manually annotated by BRENDA team
Son, H.; Kim, K.
Structural insights into a novel class of aspartate aminotransferase from Corynebacterium glutamicum
PLoS ONE
11
e0158402
2016
Corynebacterium glutamicum (Q8NTR2), Corynebacterium glutamicum, Corynebacterium glutamicum ATCC 13032 (Q8NTR2)
Manually annotated by BRENDA team
Thyagarajan, R.; Keshav, V.; Narendrakumar, G.; Masilamani Selvam, M.; Rameshkumar, V.
Effect of copper sulphate on aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activity in freshwater fish Ariopsis seemanni
Res. J. Pharm. Biol. Chem. Sci.
6
1219-1224
2015
Ariopsis seemanni
-
Manually annotated by BRENDA team
Dajnowicz, S.; Cheng, Y.; Daemen, L.; Weiss, K.; Gerlits, O.; Mueser, T.; Kovalevsky, A.
Substrate binding stiffens aspartate aminotransferase by altering the enzyme picosecond vibrational dynamics
ACS Omega
51
18787-18797
2020
Sus scrofa (P00503)
Manually annotated by BRENDA team
Holt, M.C.; Assar, Z.; Beheshti Zavareh, R.; Lin, L.; Anglin, J.; Mashadova, O.; Haldar, D.; Mullarky, E.; Kremer, D.M.; Cantley, L.C.; Kimmelman, A.C.; Stein, A.J.; Lairson, L.L.; Lyssiotis, C.A.
Biochemical characterization and structure-based mutational analysis provide insight into the binding and mechanism of action of novel aspartate aminotransferase inhibitors
Biochemistry
57
6604-6614
2018
Homo sapiens (P17174)
Manually annotated by BRENDA team
Anglin, J.; Zavareh, R.B.; Sander, P.N.; Haldar, D.; Mullarky, E.; Cantley, L.C.; Kimmelman, A.C.; Lyssiotis, C.A.; Lairson, L.L.
Discovery and optimization of aspartate aminotransferase 1 inhibitors to target redox balance in pancreatic ductal adenocarcinoma
Bioorg. Med. Chem. Lett.
28
2675-2678
2018
Homo sapiens (P17174)
Manually annotated by BRENDA team
Rasool, A.; Zulfajri, M.; Gulzar, A.; Hanafiah, M.M.; Unnisa, S.A.; Mahboob, M.
In vitro effects of cobalt nanoparticles on aspartate aminotransferase and alanine aminotransferase activities of wistar rats
Biotechnol. Rep.
26
e00453
2020
Rattus norvegicus
Manually annotated by BRENDA team
Yu, J.; Li, J.; Cao, S.; Wu, T.; Zeng, S.; Zhang, H.; Liu, J.; Jiao, Q.
Chemoenzymatic synthesis of L-3,4-dimethoxyphenyl-alanine and its analogues using aspartate aminotransferase as a key catalyst
Catal. Commun.
120
28-32
2019
Escherichia coli
-
Manually annotated by BRENDA team
Andreessen, C.; Gerlt, V.; Steinbuechel, A.
Conversion of cysteine to 3-mercaptopyruvic acid by bacterial aminotransferases
Enzyme Microb. Technol.
99
38-48
2017
Cupriavidus necator, Shimwellia blattae, Escherichia coli (P00509), Advenella mimigardefordensis (W0PFQ7), Advenella mimigardefordensis DPN7 (W0PFQ7), Escherichia coli MG1655 (P00509), Shimwellia blattae ATCC 33430
Manually annotated by BRENDA team
Reidman, S.; Cohen, A.; Kupiec, M.; Weisman, R.
The cytosolic form of aspartate aminotransferase is required for full activation of TOR complex 1 in fission yeast
J. Biol. Chem.
294
18244-18255
2019
Schizosaccharomyces pombe
Manually annotated by BRENDA team
Jia, Y.; Lu, L.; Yuan, C.; Feng, S.; Zhu, M.
Aspartate aminotransferase is potently inhibited by copper complexes Exploring copper complex-binding proteome
J. Inorg. Biochem.
170
46-54
2017
Rattus norvegicus
Manually annotated by BRENDA team
Zareei, S.; Boojar, M.M.A.; Amanlou, M.
Inhibition of liver alanine aminotransferase and aspartate aminotransferase by hesperidin and its aglycone hesperetin An in vitro and in silico study
Life Sci.
178
49-55
2017
Rattus norvegicus
Manually annotated by BRENDA team
Mueser, T.; Drago, V.; Kovalevsky, A.; Dajnowicz, S.
Pyridoxal 5'-phosphate dependent reactions Analyzing the mechanism of aspartate aminotransferase
Methods Enzymol.
634
333-359
2020
Sus scrofa (P00503), Escherichia coli (P00509)
Manually annotated by BRENDA team
Jansen, R.S.; Mandyoli, L.; Hughes, R.; Wakabayashi, S.; Pinkham, J.T.; Selbach, B.; Guinn, K.M.; Rubin, E.J.; Sacchettini, J.C.; Rhee, K.Y.
Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis
Nat. Commun.
11
1960
2020
Mycobacterium tuberculosis (O69689), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (O69689)
Manually annotated by BRENDA team
Wang, C.; Chen, H.; Ying, W.
Cytosolic aspartate aminotransferase mediates the mitochondrial membrane potential and cell survival by maintaining the calcium homeostasis of BV2 microglia
NeuroReport
29
99-105
2018
Mus musculus
Manually annotated by BRENDA team
Schlueter, U.; Braeutigam, A.; Droz, J.M.; Schwender, J.; Weber, A.P.M.
The role of alanine and aspartate aminotransferases in C4 photosynthesis
Plant Biol.
21 Suppl 1
64-76
2019
Amaranthus caudatus, Arabidopsis thaliana, Atriplex rosea, Flaveria bidentis, Oryza sativa, Megathyrsus maximus, Panicum miliaceum, Setaria italica, Setaria viridis, Sorghum bicolor, Zea mays, Flaveria robusta, Atriplex prostrata, Panicum virgatum, Gynandropsis gynandra, Tarenaya hassleriana, Dichanthelium clandestinum, Alloteropsis semialata subsp. eckloniana, Alloteropsis semialata
Manually annotated by BRENDA team
Holland, C.K.; Berkovich, D.A.; Kohn, M.L.; Maeda, H.; Jez, J.M.
Structural basis for substrate recognition and inhibition of prephenate aminotransferase from Arabidopsis
Plant J.
94
304-314
2018
Arabidopsis thaliana (Q9SIE1), Arabidopsis thaliana
Manually annotated by BRENDA team
Jeong, S.Y.; Jin, H.; Chang, J.H.
Crystal structure of L-aspartate aminotransferase from Schizosaccharomyces pombe
PLoS ONE
14
e0221975
2019
Schizosaccharomyces pombe (O42652), Schizosaccharomyces pombe, Schizosaccharomyces pombe 972 (O42652)
Manually annotated by BRENDA team
Gharib, G.; Chohan, S.; Rashid, N.; Akhtar, M.
Heterologous gene expression and characterization of recombinant aspartate aminotransferase from Geobacillus thermopakistaniensis
Protein Expr. Purif.
175
105709
2020
Geobacillus sp. MAS1 (A0A6F8T0V6)
Manually annotated by BRENDA team
El Omari, R.; Ben Mrid, R.; Bouargalne, Y.; Nhiri, M.
Prokaryotic-type aspartate aminotransferase in Sorghum leaves localization, distribution and potential role
Russ. J. Plant Physiol.
67
697-702
2020
Sorghum bicolor subsp. drummondii
-
Manually annotated by BRENDA team