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Disease on EC 2.6.1.42 - branched-chain-amino-acid transaminase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acute Coronary Syndrome
THE BRANCHED-CHAIN AMINO ACID TRANSAMINASE 1 -23C/G POLYMORPHISM CONFERS PROTECTION AGAINST ACUTE CORONARY SYNDROME.
Adenocarcinoma
[The Expression and Significance of c-myc and bcat1 in Cervical Cancer].
Adenoma
Evaluation of a panel of tumor-specific differentially-methylated DNA regions in IRF4, IKZF1 and BCAT1 for blood-based detection of colorectal cancer.
Alzheimer Disease
Altered Expression of Human Mitochondrial Branched Chain Aminotransferase in Dementia with Lewy Bodies and Vascular Dementia.
BCAT-induced autophagy regulates A? load through an interdependence of redox state and PKC phosphorylation-implications in Alzheimer's disease.
Regional Increase in the Expression of the BCAT Proteins in Alzheimer's Disease Brain: Implications in Glutamate Toxicity.
THE BRANCHED-CHAIN AMINOTRANSFERASE PROTEINS: NOVEL REDOX CHAPERONES FOR PROTEIN DISULFIDE ISOMERASE- IMPLICATIONS IN ALZHEIMER'S DISEASE.
Astrocytoma
Loss of BCAT1 Expression is a Sensitive Marker for IDH-Mutant Diffuse Glioma.
Blast Crisis
Cancer progression by reprogrammed BCAA metabolism in myeloid leukaemia.
Brain Diseases
Expanding the genetic and phenotypic spectrum of branched-chain amino acid transferase 2 deficiency.
Brain Neoplasms
Differential expression and prognostic significance of SOX genes in pediatric medulloblastoma and ependymoma identified by microarray analysis.
branched-chain-amino-acid transaminase deficiency
BCATm deficiency ameliorates endotoxin-induced decrease in muscle protein synthesis and improves survival in septic mice.
Branched-chain aminotransferase deficiency in Chinese hamster cells complemented by two independent genes on human chromosomes 12 and 19.
ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease.
Expanding the genetic and phenotypic spectrum of branched-chain amino acid transferase 2 deficiency.
Localization of a gene which complements branched-chain amino acid transaminase deficiency to the short arm of human chromosome 12.
Breast Neoplasms
BCATc modulates crosstalk between the PI3K/Akt and the Ras/ERK pathway regulating proliferation in triple negative breast cancer.
Branched-chain amino acid transaminase 1 (BCAT1) promotes the growth of breast cancer cells through improving mTOR-mediated mitochondrial biogenesis and function.
DOT1L histone methyltransferase regulates the expression of BCAT1 and is involved in sphere formation and cell migration of breast cancer cell lines.
The branched-chain amino acid transaminase 1 sustains growth of antiestrogen-resistant and ER?-negative breast cancer.
Carcinogenesis
BCAT1 expression associates with ovarian cancer progression: possible implications in altered disease metabolism.
BCAT1 Overexpression Promotes Proliferation, Invasion, and Wnt Signaling in Non-Small Cell Lung Cancers.
Data mining of the expression and regulatory role of BCAT1 in hepatocellular carcinoma.
Identification of genes with differential expression in chemoresistant epithelial ovarian cancer using high-density oligonucleotide microarrays.
Isozyme patterns of branched-chain amino acid transaminase during cellular differentiation and carcinogenesis.
Silencing of Long Noncoding RNA LINC00324 Interacts with MicroRNA-3200-5p to Attenuate the Tumorigenesis of Gastric Cancer via Regulating BCAT1.
Carcinoma
BCAT1 overexpression is an indicator of poor prognosis in patients with urothelial carcinomas of the upper urinary tract and urinary bladder.
BCAT1 overexpression regulates proliferation and c?Myc/GLUT1 signaling in head and neck squamous cell carcinoma.
Carcinoma, Hepatocellular
BCAT1 expression in hepatocellular carcinoma.
BCAT1 promotes tumor cell migration and invasion in hepatocellular carcinoma.
BCAT1, a key prognostic predictor of hepatocellular carcinoma, promotes cell proliferation and induces chemoresistance to cisplatin.
Branched chain aminotransferase isoenzymes. Purification and characterization of the rat brain isoenzyme.
Branched-chain amino acid aminotransferase 2 regulates ferroptotic cell death in cancer cells.
Cloning and expression of the mammalian cytosolic branched chain aminotransferase isoenzyme.
Data mining of the expression and regulatory role of BCAT1 in hepatocellular carcinoma.
Isozyme patterns of branched-chain amino acid transaminase in various rat hepatomas.
LncRNA CRNDE promotes hepatocellular carcinoma cell proliferation, invasion, and migration through regulating miR-203/ BCAT1 axis.
Mitochondrial branched chain aminotransferase gene expression in AS-30D hepatoma rat cells and during liver regeneration after partial hepatectomy in rat.
Carcinoma, Ovarian Epithelial
BCAT1 expression associates with ovarian cancer progression: possible implications in altered disease metabolism.
Carcinoma, Squamous Cell
BCAT1 overexpression regulates proliferation and c?Myc/GLUT1 signaling in head and neck squamous cell carcinoma.
[The Expression and Significance of c-myc and bcat1 in Cervical Cancer].
Cardiovascular Diseases
Oxoeicosanoid receptor inhibition alleviates acute myocardial infarction through activation of BCAT1.
Chondrosarcoma
Leucine and branched-chain amino acid metabolism contribute to the growth of bone sarcomas by regulating AMPK and mTORC1 signaling.
Colorectal Neoplasms
A cross-sectional study comparing a blood test for methylated BCAT1 and IKZF1 tumor-derived DNA with CEA for detection of recurrent colorectal cancer.
BCATc modulates crosstalk between the PI3K/Akt and the Ras/ERK pathway regulating proliferation in triple negative breast cancer.
Circulating tumour DNA for monitoring colorectal cancer-a prospective cohort study to assess relationship to tissue methylation, cancer characteristics and surgical resection.
Detection of Circulating Tumor DNA Methylation in Diagnosis of Colorectal Cancer.
Differential expression of the BCAT isoforms between breast cancer subtypes.
Evaluation of a panel of tumor-specific differentially-methylated DNA regions in IRF4, IKZF1 and BCAT1 for blood-based detection of colorectal cancer.
Evaluation of an assay for methylated BCAT1 and IKZF1 in plasma for detection of colorectal neoplasia.
Evaluation of Circulating Tumor DNA for Methylated BCAT1 and IKZF1 to Detect Recurrence of Stage II/Stage III Colorectal Cancer (CRC).
Evaluation of Methylation Biomarkers for Detection of Circulating Tumor DNA and Application to Colorectal Cancer.
Long non-coding RNA TMPO-AS1 facilitates the progression of colorectal cancer cells via sponging miR-98-5p to upregulate BCAT1 expression.
Methylation and Gene Expression of BCAT1 and IKZF1 in Colorectal Cancer Tissues.
Relationship between post-surgery detection of methylated circulating tumor DNA with risk of residual disease and recurrence-free survival.
Validation of a Circulating Tumor-Derived DNA Blood Test for Detection of Methylated BCAT1 and IKZF1 DNA.
Variables associated with detection of methylated BCAT1 or IKZF1 in blood from patients without colonoscopically-evident colorectal cancer.
Dementia
Altered Expression of Human Mitochondrial Branched Chain Aminotransferase in Dementia with Lewy Bodies and Vascular Dementia.
Dementia, Vascular
Altered Expression of Human Mitochondrial Branched Chain Aminotransferase in Dementia with Lewy Bodies and Vascular Dementia.
Diabetes Mellitus, Type 2
Identification of novel candidate genes for type 2 diabetes from a genome-wide association scan in the Old Order Amish: evidence for replication from diabetes-related quantitative traits and from independent populations.
Dyslipidemias
Inhibitors of BCATm: A Tough Nut To Crack.
Endometrial Hyperplasia
BCAT1 promotes proliferation of endometrial cancer cells through reprogrammed BCAA metabolism.
Endometrial Neoplasms
BCAT1 promotes proliferation of endometrial cancer cells through reprogrammed BCAA metabolism.
Ependymoma
Differential expression and prognostic significance of SOX genes in pediatric medulloblastoma and ependymoma identified by microarray analysis.
Fatty Liver
Changes in activity levels and isozyme patterns of isoleucine aminotransferase in response to experimentally induced hepatic lesion.
Genome-scale metabolic modelling of hepatocytes reveals serine deficiency in patients with non-alcoholic fatty liver disease.
Glioblastoma
Assessment of bevacizumab resistance increased by expression of BCAT1 in IDH1 wild-type glioblastoma: application of DSC perfusion MR imaging.
BCAT1 is a New MR Imaging-related Biomarker for Prognosis Prediction in IDH1-wildtype Glioblastoma Patients.
BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1.
Enrichment of branched chain amino acid transaminase 1 correlates with multiple biological processes and contributes to poor survival of IDH1 wild-type gliomas.
Intact Protein Analysis at 21 Tesla and X-Ray Crystallography Define Structural Differences in Single Amino Acid Variants of Human Mitochondrial Branched-Chain Amino Acid Aminotransferase 2 (BCAT2).
Multistage Ultraviolet Photodissociation Mass Spectrometry To Characterize Single Amino Acid Variants of Human Mitochondrial BCAT2.
Regulation of branched-chain amino acid metabolism by hypoxia-inducible factor in glioblastoma.
Glioma
BCAT1 defines gliomas by IDH status.
BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1.
BCATc modulates crosstalk between the PI3K/Akt and the Ras/ERK pathway regulating proliferation in triple negative breast cancer.
Clinical aggressiveness of malignant gliomas is linked to augmented metabolism of amino acids.
Diagnostic value of glutamate with 2-hydroxyglutarate in magnetic resonance spectroscopy for IDH1 mutant glioma.
Differential expression of the BCAT isoforms between breast cancer subtypes.
Enrichment of branched chain amino acid transaminase 1 correlates with multiple biological processes and contributes to poor survival of IDH1 wild-type gliomas.
In search of druggable targets for GBM amino acid metabolism.
LINC00963 Confers Oncogenic Properties in Glioma by Regulating the miR-506/BCAT1 Axis.
Loss of BCAT1 Expression is a Sensitive Marker for IDH-Mutant Diffuse Glioma.
Neuro-oncology: BCAT1 promotes cell proliferation in aggressive gliomas.
Systematic identification of single amino Acid variants in glioma stem-cell-derived chromosome 19 proteins.
Hypertension
Genetic susceptibility to salt-sensitive hypertension in a Han Chinese population: a validation study of candidate genes.
Insulin Resistance
Effect of the BCAT2 polymorphism (rs11548193) on plasma branched-chain amino acid concentrations after dietary intervention in subjects with obesity and insulin resistance.
Serum amino acid concentrations are modified by age, insulin resistance, and BCAT2 rs11548193 and BCKDH rs45500792 polymorphisms in subjects with obesity.
Leukemia
Curcumin induces apoptosis by inhibiting BCAT1 expression and mTOR signaling in cytarabine?resistant myeloid leukemia cells.
Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation.
Leukemia, Myeloid
BCAT1 Enhances BCAA Production to Drive Myeloid Leukemia.
Curcumin induces apoptosis by inhibiting BCAT1 expression and mTOR signaling in cytarabine?resistant myeloid leukemia cells.
Liver Failure
Ammonia detoxification by accelerated oxidation of branched chain amino acids in brains of acute hepatic failure rats.
Liver Neoplasms
Circulating Tumor Cells Undergoing EMT Provide a Metric for Diagnosis and Prognosis of Patients with Hepatocellular Carcinoma.
LncRNA CRNDE promotes hepatocellular carcinoma cell proliferation, invasion, and migration through regulating miR-203/ BCAT1 axis.
Liver Neoplasms, Experimental
Isozyme patterns of branched-chain amino acid transminase in cultured Morris hepatoma 7316A.
Lung Diseases
BCAT1 binds the RNA-binding protein ZNF423 to activate autophagy via the IRE1-XBP-1-RIDD axis in hypoxic PASMCs.
Lung Neoplasms
BCAT1 Overexpression Promotes Proliferation, Invasion, and Wnt Signaling in Non-Small Cell Lung Cancers.
Lymphatic Metastasis
BCAT1 promotes proliferation of endometrial cancer cells through reprogrammed BCAA metabolism.
Over-expression of BCAT1 is a prognostic marker in gastric cancer.
Lymphoma
Mice deficient in the mitochondrial branched-chain aminotransferase (BCATm) respond with delayed tumour growth to a challenge with EL-4 lymphoma.
Maple Syrup Urine Disease
ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease.
Medulloblastoma
Differential expression and prognostic significance of SOX genes in pediatric medulloblastoma and ependymoma identified by microarray analysis.
Melanoma
BCAT1 and miR-2504: novel methylome signature distinguishes spindle/desmoplastic melanoma from superficial malignant peripheral nerve sheath tumor.
BCAT1 knockdown-mediated suppression of melanoma cell proliferation and migration is associated with reduced oxidative phosphorylation.
Melanoma, Experimental
BCAT1 knockdown-mediated suppression of melanoma cell proliferation and migration is associated with reduced oxidative phosphorylation.
Movement Disorders
High-throughput behavioral screen in C. elegans reveals Parkinson's disease drug candidates.
Metformin rescues Parkinson's disease phenotypes caused by hyperactive mitochondria.
Myocardial Infarction
Oxoeicosanoid receptor inhibition alleviates acute myocardial infarction through activation of BCAT1.
Nasopharyngeal Carcinoma
Flotillin-2 promotes cell proliferation via activating the c-Myc/BCAT1 axis by suppressing miR-33b-5p in nasopharyngeal carcinoma.
Over-expression of BCAT1, a c-Myc target gene, induces cell proliferation, migration and invasion in nasopharyngeal carcinoma.
Neoplasm Metastasis
BCAT1 Overexpression Promotes Proliferation, Invasion, and Wnt Signaling in Non-Small Cell Lung Cancers.
BCAT1 overexpression regulates proliferation and c?Myc/GLUT1 signaling in head and neck squamous cell carcinoma.
BCAT1 promotes proliferation of endometrial cancer cells through reprogrammed BCAA metabolism.
BCATc modulates crosstalk between the PI3K/Akt and the Ras/ERK pathway regulating proliferation in triple negative breast cancer.
Differential expression and prognostic significance of SOX genes in pediatric medulloblastoma and ependymoma identified by microarray analysis.
Over-expression of BCAT1 is a prognostic marker in gastric cancer.
Relationship between post-surgery detection of methylated circulating tumor DNA with risk of residual disease and recurrence-free survival.
Src promotes castration-recurrent prostate cancer through androgen receptor-dependent canonical and non-canonical transcriptional signatures.
[The Expression and Significance of c-myc and bcat1 in Cervical Cancer].
Neoplasms
A Blood Test for Methylated BCAT1 and IKZF1 vs. a Fecal Immunochemical Test for Detection of Colorectal Neoplasia.
A two-gene blood test for methylated DNA sensitive for colorectal cancer.
Assay of leucine aminotransferase in rat tissues and tumors.
Assessment of bevacizumab resistance increased by expression of BCAT1 in IDH1 wild-type glioblastoma: application of DSC perfusion MR imaging.
BCAT1 Activates PI3K/AKT/mTOR Pathway and Contributes to the Angiogenesis and Tumorigenicity of Gastric Cancer.
BCAT1 and miR-2504: novel methylome signature distinguishes spindle/desmoplastic melanoma from superficial malignant peripheral nerve sheath tumor.
BCAT1 decreases the sensitivity of cancer cells to cisplatin by regulating mTOR-mediated autophagy via branched-chain amino acid metabolism.
BCAT1 Enhances BCAA Production to Drive Myeloid Leukemia.
BCAT1 expression associates with ovarian cancer progression: possible implications in altered disease metabolism.
BCAT1 knockdown-mediated suppression of melanoma cell proliferation and migration is associated with reduced oxidative phosphorylation.
BCAT1 overexpression is an indicator of poor prognosis in patients with urothelial carcinomas of the upper urinary tract and urinary bladder.
BCAT1 Overexpression Promotes Proliferation, Invasion, and Wnt Signaling in Non-Small Cell Lung Cancers.
BCAT1 overexpression regulates proliferation and c?Myc/GLUT1 signaling in head and neck squamous cell carcinoma.
BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1.
BCAT1 promotes proliferation of endometrial cancer cells through reprogrammed BCAA metabolism.
BCAT1 promotes tumor cell migration and invasion in hepatocellular carcinoma.
BCAT1, a key prognostic predictor of hepatocellular carcinoma, promotes cell proliferation and induces chemoresistance to cisplatin.
BCAT2-mediated BCAA catabolism is critical for development of pancreatic ductal adenocarcinoma.
BCATc modulates crosstalk between the PI3K/Akt and the Ras/ERK pathway regulating proliferation in triple negative breast cancer.
Branched-chain amino acid aminotransferase 2 regulates ferroptotic cell death in cancer cells.
Branched-chain amino acid metabolism in cancer.
Circulating tumour DNA for monitoring colorectal cancer-a prospective cohort study to assess relationship to tissue methylation, cancer characteristics and surgical resection.
Curcumin induces apoptosis by inhibiting BCAT1 expression and mTOR signaling in cytarabine?resistant myeloid leukemia cells.
Data mining of the expression and regulatory role of BCAT1 in hepatocellular carcinoma.
Detection of Circulating Tumor DNA Methylation in Diagnosis of Colorectal Cancer.
Differential expression and prognostic significance of SOX genes in pediatric medulloblastoma and ependymoma identified by microarray analysis.
Differential expression of the BCAT isoforms between breast cancer subtypes.
Enrichment of branched chain amino acid transaminase 1 correlates with multiple biological processes and contributes to poor survival of IDH1 wild-type gliomas.
Evaluation of a panel of tumor-specific differentially-methylated DNA regions in IRF4, IKZF1 and BCAT1 for blood-based detection of colorectal cancer.
Evaluation of an assay for methylated BCAT1 and IKZF1 in plasma for detection of colorectal neoplasia.
Evaluation of Circulating Tumor DNA for Methylated BCAT1 and IKZF1 to Detect Recurrence of Stage II/Stage III Colorectal Cancer (CRC).
Functional evidence for a nasopharyngeal carcinoma-related gene BCAT1 located at 12p12.
Hyperpolarized [1-13C] glutamate: a metabolic imaging biomarker of IDH1 mutational status in glioma.
Identification of genes with differential expression in chemoresistant epithelial ovarian cancer using high-density oligonucleotide microarrays.
Intact Protein Analysis at 21 Tesla and X-Ray Crystallography Define Structural Differences in Single Amino Acid Variants of Human Mitochondrial Branched-Chain Amino Acid Aminotransferase 2 (BCAT2).
Isozyme patterns of branched-chain amino acid transaminase in human tissues and tumors.
Leucine and branched-chain amino acid metabolism contribute to the growth of bone sarcomas by regulating AMPK and mTORC1 signaling.
LINC00963 Confers Oncogenic Properties in Glioma by Regulating the miR-506/BCAT1 Axis.
LncRNA CRNDE promotes hepatocellular carcinoma cell proliferation, invasion, and migration through regulating miR-203/ BCAT1 axis.
Loss of BCAT1 Expression is a Sensitive Marker for IDH-Mutant Diffuse Glioma.
Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation.
Methylation and Gene Expression of BCAT1 and IKZF1 in Colorectal Cancer Tissues.
Mice deficient in the mitochondrial branched-chain aminotransferase (BCATm) respond with delayed tumour growth to a challenge with EL-4 lymphoma.
MicroRNA-218 inhibits tumor growth and increases chemosensitivity to CDDP treatment by targeting BCAT1 in prostate cancer.
miR-98-5p inhibits gastric cancer cell stemness and chemoresistance by targeting branched-chain aminotransferases 1.
Multistage Ultraviolet Photodissociation Mass Spectrometry To Characterize Single Amino Acid Variants of Human Mitochondrial BCAT2.
Over-expression of BCAT1 is a prognostic marker in gastric cancer.
Prognostic significance of branched-chain amino acid transferase 1 and CD133 in triple-negative breast cancer.
The branched-chain amino acid transaminase 1 sustains growth of antiestrogen-resistant and ER?-negative breast cancer.
The role of DNMT1/hsa-miR-124-3p/BCAT1 pathway in regulating growth and invasion of esophageal squamous cell carcinoma.
Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers.
Tumour-reprogrammed stromal BCAT1 fuels branched-chain ketoacid dependency in stromal-rich PDAC tumours.
Variables associated with detection of methylated BCAT1 or IKZF1 in blood from patients without colonoscopically-evident colorectal cancer.
[The Expression and Significance of c-myc and bcat1 in Cervical Cancer].
Nephrosis
Hepatic histidase and muscle branched chain aminotransferase gene expression in experimental nephrosis.
Nephrotic Syndrome
Reduced kidney branched chain aminotransferase expression in puromycin aminonucleoside-induced nephrotic syndrome.
Neurodegenerative Diseases
The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases.
Neurofibrosarcoma
BCAT1 and miR-2504: novel methylome signature distinguishes spindle/desmoplastic melanoma from superficial malignant peripheral nerve sheath tumor.
Non-alcoholic Fatty Liver Disease
Branched chain amino acid transaminase 1 (BCAT1) is overexpressed and hypomethylated in patients with non-alcoholic fatty liver disease who experience adverse clinical events: A pilot study.
Obesity
Adverse Childhood Experiences, Epigenetic Measures, and Obesity in Youth.
Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library.
Effect of the BCAT2 polymorphism (rs11548193) on plasma branched-chain amino acid concentrations after dietary intervention in subjects with obesity and insulin resistance.
Inhibitors of BCATm: A Tough Nut To Crack.
Metabolic Fate of Branched-Chain Amino Acids During Adipogenesis, in Adipocytes From Obese Mice and C2C12 Myotubes.
Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism.
Serum amino acid concentrations are modified by age, insulin resistance, and BCAT2 rs11548193 and BCKDH rs45500792 polymorphisms in subjects with obesity.
Osteosarcoma
Leucine and branched-chain amino acid metabolism contribute to the growth of bone sarcomas by regulating AMPK and mTORC1 signaling.
Ovarian Neoplasms
BCAT1 expression associates with ovarian cancer progression: possible implications in altered disease metabolism.
Pancreatic Neoplasms
Acetylation promotes BCAT2 degradation to suppress BCAA catabolism and pancreatic cancer growth.
Branched-chain amino acid aminotransferase 2 regulates ferroptotic cell death in cancer cells.
Pancreatitis
[Diagnostic importance of determining leucine aminotransferase activity in acute pancreatitis]
Parkinson Disease
High-throughput behavioral screen in C. elegans reveals Parkinson's disease drug candidates.
Metformin rescues Parkinson's disease phenotypes caused by hyperactive mitochondria.
Prostatic Neoplasms
MicroRNA-218 inhibits tumor growth and increases chemosensitivity to CDDP treatment by targeting BCAT1 in prostate cancer.
The feasibility of assessing branched-chain amino acid metabolism in cellular models of prostate cancer with hyperpolarized [1-(13)C]-ketoisocaproate.
Sarcoma, Avian
Change of isozyme pattern during activation of a transforming gene product: its relation to other biochemical markers of cellular transformation and differentiation.
Scrapie
Arabidopsis and maize RidA proteins preempt reactive enamine/imine damage to branched-chain amino acid biosynthesis in plastids.
Crystal structures of RidA, an important enzyme for the prevention of toxic side products.
RidA proteins prevent metabolic damage inflicted by PLP-dependent dehydratases in all domains of life.
Suppressor Analyses Identify Threonine as a Modulator of ridA Mutant Phenotypes in Salmonella enterica.
Squamous Cell Carcinoma of Head and Neck
BCAT1 overexpression regulates proliferation and c?Myc/GLUT1 signaling in head and neck squamous cell carcinoma.
Starvation
Amino acid metabolism enzyme activities in the obese Zucker rat.
Amino-acid metabolism enzyme activities in rat white adipose tissue.
Impact of short-term starvation and refeeding on the expression of KLF15 and regulatory mechanism of branched-chain amino acids metabolism in muscle of Chinese soft-shelled turtle (Pelodiscus sinensis).
MiR-125a-3p-KLF15-BCAA Regulates the Skeletal Muscle Branched-Chain Amino Acid Metabolism in Nile Tilapia (Oreochromis niloticus) During Starvation.
Studies on metabolism of branched chain amino acids in brain and other tissues of rat with special reference to leucine.
Stomach Neoplasms
BCAT1 Activates PI3K/AKT/mTOR Pathway and Contributes to the Angiogenesis and Tumorigenicity of Gastric Cancer.
BCAT1 and miR-2504: novel methylome signature distinguishes spindle/desmoplastic melanoma from superficial malignant peripheral nerve sheath tumor.
miR-98-5p inhibits gastric cancer cell stemness and chemoresistance by targeting branched-chain aminotransferases 1.
Over-expression of BCAT1 is a prognostic marker in gastric cancer.
Silencing of Long Noncoding RNA LINC00324 Interacts with MicroRNA-3200-5p to Attenuate the Tumorigenesis of Gastric Cancer via Regulating BCAT1.
Teratocarcinoma
Identification of amplified genes from SV40 large T antigen-induced rat PNET cell lines by subtractive cDNA analysis and radiation hybrid mapping.
Thyroid Neoplasms
Six1 Overexpression Promotes Glucose Metabolism and Invasion Through Regulation of GLUT3, MMP2 and Snail in Thyroid Cancer Cells.
Triple Negative Breast Neoplasms
BCATc modulates crosstalk between the PI3K/Akt and the Ras/ERK pathway regulating proliferation in triple negative breast cancer.
Prognostic significance of branched-chain amino acid transferase 1 and CD133 in triple-negative breast cancer.
The branched-chain amino acid transaminase 1 sustains growth of antiestrogen-resistant and ER?-negative breast cancer.
Tuberculosis
Branched-chain amino acid aminotransferase and methionine formation in Mycobacterium tuberculosis.
Chemical Mechanism of the Branched-Chain Aminotransferase IlvE from Mycobacterium tuberculosis.
Mechanism-Based Inhibition of the Mycobacterium tuberculosis Branched-Chain Aminotransferase by d- and l-Cycloserine.
Structural analysis of mycobacterial branched-chain aminotransferase: implications for inhibitor design.
The 1.9 A structure of the branched-chain amino-acid transaminase (IlvE) from Mycobacterium tuberculosis.
Uterine Cervical Neoplasms
[The Expression and Significance of c-myc and bcat1 in Cervical Cancer].