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Reference on EC 2.6.1.44 - alanine-glyoxylate transaminase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Koide, Y.; Honma, M.; Shimomura, T.
L-alanine-alpha-keto acid aminotransferase of Pseudomonas sp.
Agric. Biol. Chem.
41
781-784
1977
Pseudomonas sp.
-
Manually annotated by BRENDA team
Rowsell, E.V.; Snell, K.; Carnie, J.A.; Rowsell, K.V.
The subcellular distribution of rat liver L-alanine-glyoxylate aminotransferase in relation to a pathway for glucose formation involving glyoxylate
Biochem. J.
127
155-156
1972
Rattus norvegicus
Manually annotated by BRENDA team
Noguchi, T.; Okuno, E.; Takada, Y.; Minatogawa, Y.; Okai, K.; Kido, R.
Characteristics of hepatic alanine-glyoxylate aminotransferase in different mammalian species
Biochem. J.
169
113-122
1978
Canis lupus familiaris, Felis catus, Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
Okuno, E.; Minatogawa, Y.; Kido, R.
Co-purification of alanine-glyoxylate aminotransferase with 2-aminobutyrate aminotransferase in rat kidney
Biochim. Biophys. Acta
715
97-104
1982
Rattus norvegicus
Manually annotated by BRENDA team
Nakamura, Y.; Tolbert, N.E.
Serine: glyoxylate, alanine:glyoxylate, and glutamate:glyoxylate aminotransferase reactions in peroxisomes from spinach leaves
J. Biol. Chem.
258
7631-7638
1983
Spinacia oleracea
Manually annotated by BRENDA team
Noguchi, T.; Fujiwara, S.; Takada, Y.; Mori, T.; Nagano, M.; Hanada, N.; Saeki, E.; Yasuo, O.
Enzymatic and immunological comparison of alanine: glyoxylate aminotransferases from different fish and mammalian livers
Comp. Biochem. Physiol. B
77
279-283
1984
Caranx chrysos, Sardinops sp., Scomberomorus sp., Sebastes carnatus
Manually annotated by BRENDA team
Takada, Y.; Noguchi, T.
Characteristics of alanine: glyoxylate aminotransferase from Saccharomyces cerevisiae, a regulatory enzyme in the glyoxylate pathway of glycine and serine biosynthesis from tricarboxylic acid-cycle intermediates
Biochem. J.
231
157-163
1985
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Okuno, E.; Ishikawa, T.; Kawai, J.; Kido, R.
Alanine:glyoxylate aminotransferase activities in liver of Suncus murinus (Insectivora)
Comp. Biochem. Physiol. B
90
773-778
1988
Suncus murinus
Manually annotated by BRENDA team
Kobayashi, S.; Hayashi, S.; Fujiwara, S.; Noguchi, T.
Identity of alanine:glyoxylate aminotransferase with alanine:2-oxoglutarate aminotransferase in rat liver cytosol
Biochimie
71
471-475
1989
Rattus norvegicus
Manually annotated by BRENDA team
Sakuraba, H.; Fujiwara, S.; Noguchi, T.
Purification and characterization of peroxisomal apo and holo alanine:glyoxylate aminotransferase from bird liver
Arch. Biochem. Biophys.
286
453-460
1991
Anas platyrhynchos domestica, Anser anser domesticus, Gallus gallus, Columba livia, Melopsittacus undulatus, Passer montanus saturatus, Phasianus versicolor, Padda oryzivora, Serinus canaria, Uroloncha striata domestica
Manually annotated by BRENDA team
Danpure, C.J.; Fryer, P.; Griffiths, S.; Guttridge, K.M.; Jennings, P.R.; Allsop, J.; Moser, A.B.; Naidu, S.; Moser, H.W.; et al.
Cytosolic compartmentalization of hepatic alanine:glyoxylate aminotransferase in patients with aberrant peroxisomal biogenesis and its effect on oxalate metabolism
J. Inherit. Metab. Dis.
17
27-40
1994
Homo sapiens
Manually annotated by BRENDA team
Horvath, V.A.P.; Wanders, R.J.A.
Aminooxy acetic acid: a selective inhibitor of alanine:glyoxylate aminotransferase and its use in the diagnosis of primary hyperoxaluria type I
Clin. Chim. Acta
243
105-114
1995
Homo sapiens
Manually annotated by BRENDA team
Ishikawa, K.; Kaneko, E.; Ichiyama, A.
Pyridoxal 5'-phosphate binding of a recombinant rat serine: pyruvate/alanine:glyoxylate aminotransferase
J. Biochem.
119
970-978
1996
Rattus norvegicus
Manually annotated by BRENDA team
Leiper, J.M.; Oatey, P.B.; Danpure, C.J.
Inhibition of alanine:glyoxylate aminotransferase 1 dimerization is a prerequisite for its peroxisome-to-mitochondrion mistargeting in primary hyperoxaluria type 1
J. Cell. Biol.
135
939-951
1996
Homo sapiens
Manually annotated by BRENDA team
Rumsby, G.; Weir, T.; Samuell, C.T.
A semiautomated alanine:glyoxylate aminotransferase assay for the tissue diagnosis of primary hyperoxaluria type 1
Ann. Clin. Biochem.
34
400-404
1997
Homo sapiens
-
Manually annotated by BRENDA team
Holbrook, J.D.; Birdsey, G.M.; Yang, Z.; Bruford, M.W.; Danpure, C.J.
Molecular adaptation of alanine: glyoxylate aminotransferase targeting in primates
Mol. Biol. Evol.
17
387-400
2000
Mico argentatus, Callithrix jacchus, Cheirogaleus medius, Homo sapiens, Macaca fuscata, Eulemur fulvus, Loris tardigradus, Nycticebus pygmaeus, Pongo pygmaeus, Saguinus oedipus, Papio anubis (Q9TSP4), Saimiri sciureus (Q9TTP0), Pan troglodytes (Q9TTP2), Pithecia pithecia (Q9TTP3), Macaca nigra (Q9TTP7), Leontopithecus rosalia (Q9TTP8), Hylobates lar (Q9TTP9), Gorilla gorilla (Q9TTQ0), Callimico goeldii (Q9TTQ8), Cercopithecus diana (Q9TTR4), Ateles paniscus (Q9TTS7)
Manually annotated by BRENDA team
Lumb, M.J.; Danpure, C.J.
Functional synergism between the most common polymorphism in human alanine:glyoxylate aminotransferase and four of the most common disease-causing mutations
J. Biol. Chem.
275
36415-36422
2000
Homo sapiens
Manually annotated by BRENDA team
Oda, T.; Uchida, C.; Miura, S.
Mitochondrial targeting signal-induced conformational change and repression of the peroxisomal targeting signal of the precursor for rat liver serine:pyruvate/alanine:glyoxylate aminotransferase
J. Biochem.
127
665-671
2000
Rattus norvegicus
Manually annotated by BRENDA team
Liepman, A.H.; Olsen, L.J.
Peroxisomal alanine: glyoxylate aminotransferase (AGT1) is a photorespiratory enzyme with multiple substrates in Arabidopsis thaliana
Plant J.
25
487-498
2001
Arabidopsis thaliana (Q56YA5), Arabidopsis thaliana
Manually annotated by BRENDA team
Zhang, X.; Roe, S.M.; Pearl, L.H.; Danpure, C.J.
Crystallization and preliminary crystallographic analysis of human alanine:glyoxylate aminotransferase and its polymorphic variants
Acta Crystallogr. Sect. D
57
1936-1937
2001
Homo sapiens
Manually annotated by BRENDA team
Han, Q.; Li, J.
Comparative characterization of Aedes 3-hydroxykynurenine transaminase/alanine glyoxylate transaminase and Drosophila serine pyruvate aminotransferase
FEBS Lett.
527
199-204
2002
Aedes aegypti, Drosophila melanogaster (Q9W3Z3), Drosophila melanogaster
Manually annotated by BRENDA team
Danpure, C.J.; Lumb, M.J.; Birdsey, G.M.; Zhang, X.
Alanine:glyoxylate aminotransferase peroxisome-to-mitochondrion mistargeting in human hereditary kidney stone disease
Biochim. Biophys. Acta
1647
70-75
2003
Homo sapiens
Manually annotated by BRENDA team
Santana, A.; Salido, E.; Torres, A.; Shapiro, L.J.
Primary hyperoxaluria type 1 in the Canary Islands: A conformational disease due to I244T mutation in the P11L-containing alanine:glyoxylate aminotransferase
Proc. Natl. Acad. Sci. USA
100
7277-7282
2003
Homo sapiens
Manually annotated by BRENDA team
Zhang, X.; Roe, S.M.; Hou, Y.; Bartlam, M.; Rao, Z.; Pearl, L.H.; Danpure, C.J.
Crystal structure of alanine:glyoxylate aminotransferase and the relationship between genotype and enzymatic phenotype in primary hyperoxaluria type 1
J. Mol. Biol.
331
643-652
2003
Homo sapiens
Manually annotated by BRENDA team
Kato, T.; Park, E.Y.
Expression of alanine:glyoxylate aminotransferase gene from Saccharomyces cerevisiae in Ashbya gossypii
Appl. Microbiol. Biotechnol.
71
46-52
2005
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Meyer, P.; Liger, D.; Leulliot, N.; Quevillon-Cheruel, S.; Zhou, C.Z.; Borel, F.; Ferrer, J.L.; Poupon, A.; Janin, J.; van Tilbeurgh, H.
Crystal structure and confirmation of the alanine:glyoxylate aminotransferase activity of the YFL030w yeast protein
Biochimie
87
1041-1047
2005
Saccharomyces cerevisiae (P43567), Saccharomyces cerevisiae
Manually annotated by BRENDA team
Sakuraba, H.; Kawakami, R.; Takahashi, H.; Ohshima, T.
Novel archaeal alanine:glyoxylate aminotransferase from Thermococcus litoralis
J. Bacteriol.
186
5513-5518
2004
Thermococcus litoralis
Manually annotated by BRENDA team
Nishijima, S.; Sugaya, K.; Morozumi, M.; Hatano, T.; Ogawa, Y.
Hepatic alanine-glyoxylate aminotransferase activity and oxalate metabolism in vitamin B6 deficient rats
J. Urol.
169
683-686
2003
Rattus norvegicus
Manually annotated by BRENDA team
Coulter-Mackie, M.B.; Lian, Q.; Applegarth, D.; Toone, J.
The major allele of the alanine:glyoxylate aminotransferase gene: nine novel mutations and polymorphisms associated with primary hyperoxaluria type 1
Mol. Genet. Metab.
86
172-178
2005
Homo sapiens (P21549), Homo sapiens
Manually annotated by BRENDA team
Liepman, A.H.; Olsen, L.J.
Alanine aminotransferase homologs catalyze the glutamate:glyoxylate aminotransferase reaction in peroxisomes of Arabidopsis
Plant Physiol.
131
215-227
2003
Arabidopsis thaliana, Arabidopsis thaliana (Q9S7E9)
Manually annotated by BRENDA team
Coulter-Mackie, M.B.; Lian, Q.; Wong, S.G.
Overexpression of human alanine:glyoxylate aminotransferase in Escherichia coli: renaturation from guanidine-HCl and affinity for pyridoxal phosphate co-factor
Protein Expr. Purif.
41
18-26
2005
Homo sapiens
Manually annotated by BRENDA team
Han, G.W.; Schwarzenbacher, R.; Page, R.; Jaroszewski, L.; Abdubek, P.; Ambing, E.; Biorac, T.; Canaves, J.M.; Chiu, H.J.; Dai, X.; Deacon, A.M.et al.
Crystal structure of an alanine-glyoxylate aminotransferase from Anabaena sp. at 1.70 A resolution reveals a noncovalently linked PLP cofactor
Proteins Struct. Funct. Bioinform.
58
971-975
2005
Anabaena sp.
Manually annotated by BRENDA team
Schlosser, T.; Gatgens, C.; Weber, U.; Stahmann, K.P.
Alanine:glyoxylate aminotransferase of Saccharomyces cerevisiae-encoding gene AGX1 and metabolic significance
Yeast
21
63-73
2004
Saccharomyces cerevisiae (P43567), Saccharomyces cerevisiae
Manually annotated by BRENDA team
Koul, S.; Johnson, T.; Pramanik, S.; Koul, H.
Cellular transfection to deliver alanine-glyoxylate aminotransferase to hepatocytes: a rational gene therapy for primary hyperoxaluria-1 (PH-1)
Am. J. Nephrol.
25
176-182
2005
Homo sapiens
Manually annotated by BRENDA team
Han, Q.; Kim, S.R.; Ding, H.; Li, J.
Evolution of two alanine glyoxylate aminotransferases in mosquito
Biochem. J.
397
473-481
2006
Aedes aegypti (Q3LSM4)
Manually annotated by BRENDA team
Huber, P.A.; Birdsey, G.M.; Lumb, M.J.; Prowse, D.T.; Perkins, T.J.; Knight, D.R.; Danpure, C.J.
Peroxisomal import of human alanine:glyoxylate aminotransferase requires ancillary targeting information remote from its C terminus
J. Biol. Chem.
280
27111-27120
2005
Homo sapiens
Manually annotated by BRENDA team
Han, Q.; Robinson, H.; Gao, Y.G.; Vogelaar, N.; Wilson, S.R.; Rizzi, M.; Li, J.
Crystal structures of Aedes aegypti alanine glyoxylate aminotransferase
J. Biol. Chem.
281
37175-37182
2006
Aedes aegypti
Manually annotated by BRENDA team
Ricoult, C.; Echeverria, L.O.; Cliquet, J.B.; Limami, A.M.
Characterization of alanine aminotransferase (AlaAT) multigene family and hypoxic response in young seedlings of the model legume Medicago truncatula
J. Exp. Bot.
57
3079-3089
2006
Medicago truncatula
Manually annotated by BRENDA team
Coulter-Mackie, M.B.; Lian, Q.
Consequences of missense mutations for dimerization and turnover of alanine:glyoxylate aminotransferase: study of a spectrum of mutations
Mol. Genet. Metab.
89
349-359
2006
Homo sapiens
Manually annotated by BRENDA team
Salido, E.C.; Li, X.M.; Lu, Y.; Wang, X.; Santana, A.; Roy-Chowdhury, N.; Torres, A.; Shapiro, L.J.; Roy-Chowdhury, J.
Alanine-glyoxylate aminotransferase-deficient mice, a model for primary hyperoxaluria that responds to adenoviral gene transfer
Proc. Natl. Acad. Sci. USA
103
18249-18254
2006
Homo sapiens
Manually annotated by BRENDA team
Sakuraba, H.; Yoneda, K.; Takeuchi, K.; Tsuge, H.; Katunuma, N.; Ohshima, T.
Structure of an archaeal alanine:glyoxylate aminotransferase
Acta Crystallogr. Sect. D
64
696-699
2008
Thermococcus litoralis (Q9C4M4)
Manually annotated by BRENDA team
Cellini, B.; Bertoldi, M.; Montioli, R.; Paiardini, A.; Borri Voltattorni, C.
Human wild-type alanine:glyoxylate aminotransferase and its naturally occurring G82E variant: functional properties and physiological implications
Biochem. J.
408
39-50
2007
Homo sapiens, Homo sapiens (A2V838)
Manually annotated by BRENDA team
Bertoldi, M.; Cellini, B.; Paiardini, A.; Montioli, R.; Borri Voltattorni, C.
Reactions of human liver peroxisomal alanine:glyoxylate aminotransferase with beta -chloro-L-alanine and L-cysteine: Spectroscopic and kinetic analysis
Biochim. Biophys. Acta
1784
1356-1362
2008
Homo sapiens (P21549)
Manually annotated by BRENDA team
Ikeda, M.; Kanouchi, H.; Minatogawa, Y.
Characterization of peroxisomal targeting signals on alanine: glyoxylate aminotransferase
Biol. Pharm. Bull.
31
131-134
2008
Homo sapiens
Manually annotated by BRENDA team
Hopper, E.D.; Pittman, A.M.; Fitzgerald, M.C.; Tucker, C.L.
In vivo and in vitro examination of stability of primary hyperoxaluria-associated human alanine:glyoxylate aminotransferase
J. Biol. Chem.
283
30493-30502
2008
Homo sapiens
Manually annotated by BRENDA team
Coulter-Mackie, M.B.; Lian, Q.
Partial trypsin digestion as an indicator of mis-folding of mutant alanine:glyoxylate aminotransferase and chaperone effects of specific ligands. Study of a spectrum of missense mutants
Mol. Genet. Metab.
94
368-374
2008
Homo sapiens
Manually annotated by BRENDA team
Cellini, B.; Montioli, R.; Bianconi, S.; Lopez-Alonso, J.P.; Voltattorni, C.B.
Construction, purification and characterization of untagged human liver alanine-glyoxylate aminotransferase expressed in Escherichia coli
Protein Pept. Lett.
15
153-159
2008
Homo sapiens
Manually annotated by BRENDA team
Djordjevic, S.; Zhang, X.; Bartlam, M.; Ye, S.; Rao, Z.; Danpure, C.J.
Structural implications of a G170R mutation of alanine:glyoxylate aminotransferase that is associated with peroxisome-to-mitochondrion mistargeting
Acta Crystallogr. Sect. F
66
233-236
2010
Homo sapiens (P21549)
Manually annotated by BRENDA team
Kameya, M.; Arai, H.; Ishii, M.; Igarashi, Y.
Purification of three aminotransferases from Hydrogenobacter thermophilus TK-6 - novel types of alanine or glycine aminotransferase
FEBS J.
277
1876-1885
2010
Hydrogenobacter thermophilus (D2Z0I0), Hydrogenobacter thermophilus TK-6 / IAM 12695 (D2Z0I0)
Manually annotated by BRENDA team
Cellini, B.; Montioli, R.; Paiardini, A.; Lorenzetto, A.; Voltattorni, C.B.
Molecular insight into the synergism between the minor allele of human liver peroxisomal alanine:glyoxylate aminotransferase and the F152I mutation
J. Biol. Chem.
284
8349-8358
2009
Homo sapiens (P21549), Homo sapiens
Manually annotated by BRENDA team
Rodionov, R.N.; Murry, D.J.; Vaulman, S.F.; Stevens, J.W.; Lentz, S.R.
Human alanine-glyoxylate aminotransferase 2 lowers asymmetric dimethylarginine and protects from inhibition of nitric oxide production
J. Biol. Chem.
285
5385-5391
2010
Homo sapiens
Manually annotated by BRENDA team
Cellini, B.; Montioli, R.; Paiardini, A.; Lorenzetto, A.; Maset, F.; Bellini, T.; Oppici, E.; Voltattorni, C.B.
Molecular defects of the glycine 41 variants of alanine glyoxylate aminotransferase associated with primary hyperoxaluria type I
Proc. Natl. Acad. Sci. USA
107
2896-2901
2010
Homo sapiens
Manually annotated by BRENDA team
Kawai, C.; Minatogawa, Y.; Akiyoshi, H.; Hirose, S.; Suehiro, T.; Tone, S.
A novel mutation of human liver alanine:glyoxylate aminotransferase causes primary hyperoxaluria type 1: immunohistochemical quantification and subcellular distribution
Acta Histochem. Cytochem.
45
121-129
2012
Homo sapiens (A2V838)
Manually annotated by BRENDA team
Caplin, B.; Wang, Z.; Slaviero, A.; Tomlinson, J.; Dowsett, L.; Delahaye, M.; Salama, A.; Salama, A.; Wheeler, D.C.; Leiper, J.
Alanine-glyoxylate aminotransferase-2 metabolizes endogenous methylarginines, regulates NO, and controls blood pressure
Arterioscler. Thromb. Vasc. Biol.
32
2892-2900
2012
Mus musculus (Q3UEG6)
Manually annotated by BRENDA team
Cellini, B.; Montioli, R.; Voltattorni, C.B.
Human liver peroxisomal alanine:glyoxylate aminotransferase: characterization of the two allelic forms and their pathogenic variants
Biochim. Biophys. Acta
1814
1577-1584
2011
Homo sapiens
Manually annotated by BRENDA team
Cellini, B.; Lorenzetto, A.; Montioli, R.; Oppici, E.; Voltattorni, C.B.
Human liver peroxisomal alanine:glyoxylate aminotransferase: Different stability under chemical stress of the major allele, the minor allele, and its pathogenic G170R variant
Biochimie
92
1801-1811
2010
Homo sapiens
Manually annotated by BRENDA team
Montioli, R.; Fargue, S.; Lewin, J.; Zamparelli, C.; Danpure, C.J.; Borri Voltattorni, C.; Cellini, B.
The N-terminal extension is essential for the formation of the active dimeric structure of liver peroxisomal alanine:glyoxylate aminotransferase
Int. J. Biochem. Cell Biol.
44
536-546
2012
Homo sapiens
Manually annotated by BRENDA team
Fargue, S.; Lewin, J.; Rumsby, G.; Danpure, C.J.
Four of the most common mutations in primary hyperoxaluria type 1 unmask the cryptic mitochondrial targeting sequence of alanine:glyoxylate aminotransferase encoded by the polymorphic minor allele
J. Biol. Chem.
288
2475-2484
2013
Homo sapiens
Manually annotated by BRENDA team
Bhadauria, V.; Banniza, S.; Vandenberg, A.; Selvaraj, G.; Wei, Y.
Alanine: Glyoxylate aminotransferase 1 is required for mobilization and utilization of triglycerides during infection process of the rice blast pathogen, Magnaporthe oryzae
Plant Signal. Behav.
7
1206-1208
2012
Pyricularia oryzae
Manually annotated by BRENDA team
Bhadauria, V.; Banniza, S.; Vandenberg, A.; Selvaraj, G.; Wei, Y.
Peroxisomal alanine: glyoxylate aminotransferase AGT1 is indispensable for appressorium function of the rice blast pathogen, Magnaporthe oryzae
PLoS ONE
7
e36266
2012
Pyricularia oryzae
Manually annotated by BRENDA team
Ichiyama, A.
Studies on a unique organelle localization of a liver enzyme, serine:pyruvate (or alanine:glyoxylate) aminotransferase
Proc. Jpn. Acad. Ser. B Phys. Biol. Sci.
87
274-286
2011
Homo sapiens
Manually annotated by BRENDA team
Oppici, E.; Roncador, A.; Montioli, R.; Bianconi, S.; Cellini, B.
Gly161 mutations associated with Primary Hyperoxaluria Type I induce the cytosolic aggregation and the intracellular degradation of the apo-form of alanine:glyoxylate aminotransferase
Biochim. Biophys. Acta
1832
2277-2288
2013
Homo sapiens
Manually annotated by BRENDA team
Fargue, S.; Knight, J.; Holmes, R.P.; Rumsby, G.; Danpure, C.J.
Effects of alanine:glyoxylate aminotransferase variants and pyridoxine sensitivity on oxalate metabolism in a cell-based cytotoxicity assay
Biochim. Biophys. Acta
1862
1055-1062
2016
Homo sapiens
Manually annotated by BRENDA team
Abe, M.; Ochi, S.; Mori, Y.; Yamazaki, K.; Ishimaru, T.; Yoshino, Y.; Fukuhara, R.; Tanimukai, S.; Matsuda, S.; Ueno, S.
Distribution of D-3-aminoisobutyrate-pyruvate aminotransferase in the rat brain
BMC Neurosci.
15
53
2014
Rattus norvegicus (Q64565)
Manually annotated by BRENDA team
Rodionov, R.N.; Martens-Lobenhoffer, J.; Brilloff, S.; Hohenstein, B.; Jarzebska, N.; Jabs, N.; Kittel, A.; Maas, R.; Weiss, N.; Bode-Bger, S.M.
Role of alanine:glyoxylate aminotransferase 2 in metabolism of asymmetric dimethylarginine in the settings of asymmetric dimethylarginine overload and bilateral nephrectomy
Nephrol. Dial. Transplant.
29
2035-2042
2014
Mus musculus
Manually annotated by BRENDA team
Oppici, E.; Fodor, K.; Paiardini, A.; Williams, C.; Voltattorni, C.B.; Wilmanns, M.; Cellini, B.
Crystal structure of the S187F variant of human liver alanine: glyoxylate [corrected] aminotransferase associated with primary hyperoxaluria type I and its functional implications
Proteins
81
1457-1465
2013
Homo sapiens (P21549)
Manually annotated by BRENDA team
Jarzebska, N.; Georgi, S.; Jabs, N.; Brilloff, S.; Maas, R.; Rodionov, R.N.; Zietz, C.; Montresor, S.; Hohenstein, B.; Weiss, N.
Kidney and liver are the main organs of expression of a key metabolic enzyme alanine glyoxylate aminotransferase 2 in humans
Atheroscler. Suppl.
40
106-112
2019
Homo sapiens (Q9BYV1), Homo sapiens
Manually annotated by BRENDA team
Dindo, M.; Grottelli, S.; Annunziato, G.; Giardina, G.; Pieroni, M.; Pampalone, G.; Faccini, A.; Cutruzzola, F.; Laurino, P.; Costantino, G.; Cellini, B.
Cycloserine enantiomers are reversible inhibitors of human alanine glyoxylate aminotransferase implications for primary hyperoxaluria type 1
Biochem. J.
476
3751-3768
2019
Homo sapiens (P21549)
Manually annotated by BRENDA team
Dindo, M.; Montioli, R.; Busato, M.; Giorgetti, A.; Cellini, B.; Borri Voltattorni, C.
Effects of interface mutations on the dimerization of alanine glyoxylate aminotransferase and implications in the mistargeting of the pathogenic variants F152I and I244T
Biochimie
131
137-148
2016
Homo sapiens (P21549), Homo sapiens
Manually annotated by BRENDA team
Han, Q.; Yang, C.; Lu, J.; Zhang, Y.; Li, J.
Metabolism of oxalate in humans a potential role kynurenine aminotransferase/glutamine transaminase/cysteine conjugate beta-lyase plays in hyperoxaluria
Curr. Med. Chem.
26
4944-4963
2019
Mus musculus (Q3UEG6), Homo sapiens (Q9BYV1)
Manually annotated by BRENDA team
Liepman, A.H.; Vijayalakshmi, J.; Peisach, D.; Hulsebus, B.; Olsen, L.J.; Saper, M.A.
Crystal structure Of photorespiratory alanine glyoxylate aminotransferase 1 (AGT1) from Arabidopsis thaliana
Front. Plant Sci.
10
1229
2019
Arabidopsis thaliana (Q56YA5), Arabidopsis thaliana
Manually annotated by BRENDA team
Dindo, M.; Oppici, E.; DellOrco, D.; Montone, R.; Cellini, B.
Correlation between the molecular effects of mutations at the dimer interface of alanine-glyoxylate aminotransferase leading to primary hyperoxaluria type I and the cellular response to vitamin B6
J. Inherit. Metab. Dis.
41
263-275
2018
Homo sapiens (P21549)
Manually annotated by BRENDA team
Sun, Y.; Li, W.; Shen, S.; Yang, X.; Lu, B.; Zhang, X.; Lu, P.; Shen, Y.; Ji, J.
Loss of alanine-glyoxylate and serine-pyruvate aminotransferase expression accelerated the progression of hepatocellular carcinoma and predicted poor prognosis
J. Transl. Med.
17
390
2019
Homo sapiens (P21549)
Manually annotated by BRENDA team
Dindo, M.; Mandrile, G.; Conter, C.; Montone, R.; Giachino, D.; Pelle, A.; Costantini, C.; Cellini, B.
The ILE56 mutation on different genetic backgrounds of alanine glyoxylate aminotransferase clinical features and biochemical characterization
Mol. Genet. Metab.
131
171-180
2020
Homo sapiens (P21549)
-
Manually annotated by BRENDA team
Parthasarathy, A.; Adams, L.E.; Savka, F.C.; Hudson, A.O.
The Arabidopsis thaliana gene annotated by the locus tag At3g08860 encodes alanine aminotransferase
Plant Direct
3
e00171
2019
Arabidopsis thaliana (Q9SR86), Arabidopsis thaliana, Arabidopsis thaliana Col7 (Q9SR86)
Manually annotated by BRENDA team