Reference on EC 2.6.1.50 - glutamine-scyllo-inositol transaminase
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Walker, J.B.
L-glutamine:keto-scyllo-inositol aminotransferase
Methods Enzymol.
43
439-443
1975
Streptomyces bikiniensis, Streptomyces griseus, Streptomyces hygroscopicus, Streptomyces ornatus
Lucher, L.A.; Chen, Y.M.; Walker, J.B.
Reactions catalyzed by purified L-glutamine:keto-scyllo-inositol aminotransferase, an enzyme required for biosynthesis of aminocyclitol antibiotics
Antimicrob. Agents Chemother.
33
452-459
1989
Micromonospora echinospora
Walker, J.B.
Enzymic synthesis of aminocyclitol moieties of aminoglycoside antibiotics from inositol by Streptomyces sp.: detection of glutamine-aminocyclitol aminotransferase and diaminocyclitol aminotransferase activities in a spectinomycin producer
J. Bacteriol.
177
818-822
1995
Streptomyces netropsis, Streptomyces griseocarneus, Streptomyces hygroscopicus
Ahlert, J.; Distler, J.; Mansouri, K.; Piepersberg, W.
Identification of stsC, the gene encoding the L-glutamine:scyllo-inosose aminotransferase from streptomycin-producing Streptomycetes
Arch. Microbiol.
168
102-113
1997
no activity in Escherichia coli, no activity in Streptomyces lividans, Streptomyces bikiniensis, Streptomyces griseus, Streptomyces hygroscopicus, Streptomyces bikiniensis NRRL 1049b
Tamegai, H.; Eguchi, T.; Kakinuma, K.
First identification of Streptomyces genes involved in the biosynthesis of 2-deoxystreptamine-containing aminoglycoside antibiotics: genetic and evolutionary analysis of L-glutamine:2-deoxy-scyllo-inose aminotransferase genes
J. Antibiot.
55
1016-1018
2002
Niallia circulans, Streptomyces ribosidificus (Q4R0W2), Streptomyces fradiae (Q53U20), Streptoalloteichus hindustanus (Q6F6I1)
Kharel, M.K.; Subba, B.; Lee, H.C.; Liou, K.; Woo, J.S.; Sohng, J.K.
An approach for cloning biosynthetic genes of 2-deoxystreptamine-containing aminocyclitol antibiotics: isolation of a biosynthetic gene cluster of tobramycin from Streptomyces tenebrarius
Biotechnol. Lett.
25
2041-2047
2003
Streptoalloteichus tenebrarius
Yokoyama, K.; Kudo, F.; Kuwahara, M.; Inomata, K.; Tamegai, H.; Eguchi, T.; Kakinuma, K.
Stereochemical recognition of doubly functional aminotransferase in 2-deoxystreptamine biosynthesis
J. Am. Chem. Soc.
127
5869-5874
2005
Niallia circulans, Niallia circulans SANK 72073
Huang, F.; Haydock, S.F.; Mironenko, T.; Spiteller, D.; Li, Y.; Spencer, J.B.
The neomycin biosynthetic gene cluster of Streptomyces fradiae NCIMB 8233: characterization of an aminotransferase involved in the formation of 2-deoxystreptamine
Org. Biomol. Chem.
3
1410-1418
2005
Streptomyces fradiae (Q53U20), Streptomyces fradiae NCIMB 8233 (Q53U20)
Kharel, M.K.; Subba, B.; Lee, H.C.; Liou, K.; Sohng, J.K.
Characterization of L-glutamine:2-deoxy-scyllo-inosose aminotransferase (tbmB) from Streptomyces tenebrarius
Bioorg. Med. Chem. Lett.
15
89-92
2005
Streptoalloteichus tenebrarius
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