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Reference on EC 2.7.2.4 - aspartate kinase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Zhang, W.W.; Jiang, W.H.; Zhao, G.P.; Yang, Y.L.; Chiao, J.S.
Expression in Escherichia coli, purification and kinetic analysis of the aspartokinase and aspartate semialdehyde dehydrogenase from the rifamycin SV-producing Amycolatopsis mediterranei U32
Appl. Microbiol. Biotechnol.
54
52-58
2000
Amycolatopsis mediterranei
Manually annotated by BRENDA team
Black, S.
Conversion of aspartic acid to homoserine
Methods Enzymol.
5
820-827
1962
Saccharomyces cerevisiae
-
Manually annotated by BRENDA team
Paulus, H.; Gray, E.
Multivalent feedback inhibition of aspartokinase in Bacillus polymyxa. I. Kinetic studies
J. Biol. Chem.
242
4980-4986
1967
Paenibacillus polymyxa
Manually annotated by BRENDA team
Kuramitsu, H.K.; Yoshimura, S.
Catalytic and regulatory properties of meso-diaminopimelate-sensitive aspartokinase from Bacillus stearothermophilus
Arch. Biochem. Biophys.
147
683-691
1971
Geobacillus stearothermophilus
Manually annotated by BRENDA team
Starnes, W.L.; Munk, P.; Maul, S.B.; Cunningham, G.N.; Cox, D.J.; Shive, W.
Threonine-sensitive aspartokinase-homoserine dehydrogenase complex, amino acid composition, molecular weight, and subunit composition of the complex
Biochemistry
11
677-687
1972
Escherichia coli, Escherichia coli ATCC 9723
Manually annotated by BRENDA team
Veron, M.; Falcoz-Kelly, F.; Cohen, G.N.
The threonine-sensitive homoserine dehydrogenase and aspartokinase activities of Escherichia coli K12. The two catalytic activities are carried by two independent regions of the polypeptide chain
Eur. J. Biochem.
28
520-527
1972
Escherichia coli
Manually annotated by BRENDA team
Biswas, C.; Paulus, H.
Multivalent feedback inhibition of aspartokinase in Bacillus polymyxa. IV. Arrangement and function of the subunits
J. Biol. Chem.
248
2894-2900
1973
Paenibacillus polymyxa, Paenibacillus polymyxa 63 / ATCC 25901
Manually annotated by BRENDA team
Dungan, S.M.; Datta, P.
Concerted feedback inhibition. Purification and some properties of aspartokinase from Pseudomonas fluorescens
J. Biol. Chem.
248
8534-8540
1973
Pseudomonas fluorescens
Manually annotated by BRENDA team
Truffa-Bachi, P.
Microbial aspartokinases
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
8
509-553
1973
Azotobacter sp., Geobacillus stearothermophilus, Bacillus cereus, Bacillus subtilis, Bacillus licheniformis, Paenibacillus polymyxa, Corynebacterium glutamicum, [Brevibacterium] flavum, Saccharomyces cerevisiae, Escherichia coli, Neurospora crassa, no activity in Edwardsiella sp., no activity in Providencia sp., Pseudomonas aeruginosa, Pseudomonas putida, Pseudomonas fluorescens, Rhodobacter capsulatus, Cereibacter sphaeroides, Rhodospirillum rubrum, Rhodocyclus tenuis, Salmonella enterica subsp. enterica serovar Typhimurium
-
Manually annotated by BRENDA team
Wong, K.F.; Dennis, D.T.
Aspartokinase from wheat germ
Plant Physiol.
51
322-326
1973
Triticum aestivum
Manually annotated by BRENDA team
Wong, K.F.; Dennis, D.T.
Aspartokinase in Lenna minor L.
Plant Physiol.
51
327-331
1973
Lemna minor
Manually annotated by BRENDA team
Dawson Funkhouser, J.; Abraham, A.; Smith, V.A.; Smith W.G.
Kinetic and molecular properties of lysine-sensitive aspartokinase. Factors influencing the lysine-mediated association reaction and their relationship to the cooperativity of lysine inhibition
J. Biol. Chem.
249
5478-5484
1974
Escherichia coli, Escherichia coli B / ATCC 11303
Manually annotated by BRENDA team
Hitchcock, M.J.M.; Hodgson, B.
Lysine- and lysine-plus-threonine-inhibitable aspartokinases in Bacillus brevis
Biochim. Biophys. Acta
445
350-363
1976
Brevibacillus brevis
Manually annotated by BRENDA team
Moir, D.; Paulus, H.
Properties and subunit structure of aspartokinase II from Bacillus subtilis VB217
J. Biol. Chem.
252
4648-4654
1977
Bacillus subtilis, Bacillus subtilis VB217
Manually annotated by BRENDA team
Saiki, T.; Yamazumi, K.; Arima, K.
Aspartokinase of an extreme thermophile Thermus flavus partial purification and some properties
Agric. Biol. Chem.
41
1651-1655
1977
Thermus thermophilus, Thermus thermophilus AT-62
-
Manually annotated by BRENDA team
Shewry, P.R.; Miflin, B.J.
Properties and regulation of aspartate kinase from barley seedlings (Hordeum vulgare L.)
Plant Physiol.
59
69-73
1977
Hordeum vulgare
Manually annotated by BRENDA team
McCarron, R.M.; Chang, Y.F.
Aspartokinase of Streptococcus mutans: purification, properties, and regulation
J. Bacteriol.
134
483-491
1978
Streptococcus mutans, Streptococcus mutans BHT
Manually annotated by BRENDA team
Kochhar, S.; Kochhar, V.K.; Sane, P.V.
Isolation, characterization and regulation of isoenzymes of aspartate kinase differentially sensitive to calmodulin from spinach leaves
Biochim. Biophys. Acta
880
220-225
1986
Spinacia oleracea
-
Manually annotated by BRENDA team
Relton, J.M.; Bonner, P.L.R.; Wallsgrove, R.M.; Lea, P.J.
Physical and kinetic properties of lysine-sensitive aspartate kinase purified from carrot cell suspension culture
Biochim. Biophys. Acta
953
48-60
1988
Daucus carota
-
Manually annotated by BRENDA team
Dotson, S.B.; Somers, D.A.; Gengenbach, B.G.
Purification and characterization of lysine-sensitive aspartate kinase from maize cell cultures
Plant Physiol.
91
1602-1608
1989
Zea mays
Manually annotated by BRENDA team
Dotson, S.B.; Somers, D.A.; Gengenbach, B.G.
Kinetic studies of lysine-sensitive aspartate kinase purified from maize suspension cultures
Plant Physiol.
93
98-104
1990
Zea mays
Manually annotated by BRENDA team
Azevedo, R.A.; Smith, R.J.; Lea, P.J.
Aspartate kinase regulation in maize: Evidence for co-purification of threonine-sensitive aspartate kinase and homoserine dehydrogenase
Phytochemistry
31
3731-3734
1992
Zea mays
-
Manually annotated by BRENDA team
Jetten, M.S.M.; Follettie, M.T.; Sinskey, A.J.
Effect of different levels of aspartokinase on the lysine production by Corynebacterium lactofermentum
Appl. Microbiol. Biotechnol.
43
76-82
1995
Corynebacterium flavescens, Corynebacterium glutamicum (Q46133), Corynebacterium glutamicum, Corynebacterium flavescens N13
Manually annotated by BRENDA team
Keng, Y.F.; Viola, R.E.
Specificity of aspartokinase III from Escherichia coli and an examination of important catalytic residues
Arch. Biochem. Biophys.
335
73-81
1996
Escherichia coli
Manually annotated by BRENDA team
Heremans, B.; Jacobs, M.
A mutant of Arabidopsis thaliana (L.) Heynh. with modified control of aspartate kinase by threonine
Biochem. Genet.
35
139-153
1997
Arabidopsis thaliana
Manually annotated by BRENDA team
Kochhar, S.; Kochhar, V.K.; Sane, P.V.
Subunit structure of lysine sensitive aspartate kinase from spinach leaves
Biochem. Mol. Biol. Int.
44
795-806
1998
Spinacia oleracea
Manually annotated by BRENDA team
Arevalo-Rodriguez, M.; Calderon, I.L.; Holmberg, S.
Mutations that cause threonine sensitivity identify catalytic and regulatory regions of the aspartate kinase of Saccharomyces cerevisiae
Yeast
15
1331-1345
1999
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Kobashi, N.; Nishiyama, M.; Tanokura, M.
Kinetic and mutation analyses of aspartate kinase from Thermus flavus
J. Biosci. Bioeng.
87
739-745
1999
Thermus thermophilus
Manually annotated by BRENDA team
Rao, S.S.; Kochhar, S.; Kochhar, V.K.
Analysis of photocontrol of aspartate kinase in barley (Hordeum vulgare L.) seedlings
Biochem. Mol. Biol. Int.
47
347-360
1999
Hordeum vulgare
Manually annotated by BRENDA team
Lugli, J.; Gaziola, S.A.; Azevedo, R.A.
Effects of calcium, S-adenosylmethionine, S-(2-aminoethyl)-L-cysteine, methionine, valine and salt concentration on rice aspartate kinase isoenzymes
Plant Sci.
150
51-58
2000
Oryza sativa
-
Manually annotated by BRENDA team
Hernando-Rico, V.; Martin, J.F.; Santamarta, I.; Liras, P.
Structure of the ask-asd operon and formation of aspartokinase subunits in the cephamycin producer \"Amycolatopsis lactamdurans\"
Microbiology
147
1547-1555
2001
Amycolatopsis lactamdurans, no activity in Streptomyces akiyoshiensis, Amycolatopsis lactamdurans LC411
Manually annotated by BRENDA team
King, N.D.; O'Brian, M.R.
Evidence for direct interaction between enzyme INtr and aspartokinase to regulate bacterial oligopeptide transport
J. Biol. Chem.
276
21311-21316
2001
Bradyrhizobium japonicum, Bradyrhizobium japonicum I110proC
Manually annotated by BRENDA team
Kobashi, N.; Nishiyama, M.; Yamane, H.
Characterization of aspartate kinase III of Bacillus subtilis
Biosci. Biotechnol. Biochem.
65
1391-1394
2001
Bacillus subtilis
Manually annotated by BRENDA team
Paris, S.; Wessel, P.M.; Dumas, R.
Overproduction, purification, and characterization of recombinant bifunctional threonine-sensitive aspartate kinase-homoserine dehydrogenase from Arabidopsis thaliana
Protein Expr. Purif.
24
105-110
2002
Arabidopsis thaliana, Arabidopsis thaliana (O81852)
Manually annotated by BRENDA team
Paris, S.; Viemon, C.; Curien, G.; Dumas, R.
Mechanism of control of Arabidopsis thaliana aspartate kinase-homoserine dehydrogenase by threonine
J. Biol. Chem.
278
5361-5366
2003
Arabidopsis thaliana
Manually annotated by BRENDA team
James, C.L.; Viola, R.E.
Production and characterization of bifunctional enzymes. Domain swapping to produce new bifunctional enzymes in the aspartate pathway
Biochemistry
41
3720-3725
2002
Escherichia coli
Manually annotated by BRENDA team
Rognes, S.E.; Dewaele, E.; Aas, S.F.; Jacobs, M.; Frankard, V.
Transcriptional and biochemical regulation of a novel Arabidopsis thaliana bifunctional aspartate kinase-homoserine dehydrogenase gene isolated by functional complementation of a yeast hom6 mutant
Plant Mol. Biol.
51
281-294
2003
Arabidopsis thaliana
Manually annotated by BRENDA team
Bareich, D.C.; Wright, G.D.
Functionally important amino acids in Saccharomyces cerevisiae aspartate kinase
Biochem. Biophys. Res. Commun.
311
597-603
2003
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Kato, C.; Kurihara, T.; Kobashi, N.; Yamane, H.; Nishiyama, M.
Conversion of feedback regulation in aspartate kinase by domain exchange
Biochem. Biophys. Res. Commun.
316
802-808
2004
Bacillus subtilis, Thermus thermophilus
Manually annotated by BRENDA team
Marina, P.; Martinez-Costa, O.H.; Calderon, I.L.; Aragon, J.J.
Characterization of the aspartate kinase from Saccharomyces cerevisiae and of its interaction with threonine
Biochem. Biophys. Res. Commun.
321
584-591
2004
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Curien, G.; Ravanel, S.; Robert, M.; Dumas, R.
Identification of six novel allosteric effectors of Arabidopsis thaliana aspartate kinase-homoserine dehydrogenase isoforms. Physiological context sets the specificity
J. Biol. Chem.
280
41178-41183
2005
Arabidopsis thaliana
Manually annotated by BRENDA team
Demidov, D.; Horstmann, C.; Meixner, M.; Pickardt, T.; Saalbach, I.; Galili, G.; Muentz, K.
Additive effects of the feed-back insensitive bacterial aspartate kinase and the Brazil nut 2S albumin on the methionine content of transgenic narbon bean (Vicia narbonensis L.)
Mol. Breed.
11
187-201
2003
Vicia narbonensis
Manually annotated by BRENDA team
Ferreira, R.R.; Vendemiatti, A.; Gratao, P.L.; Lea, P.J.; Azevedo, R.A.
Determination of aspartate kinase activity in maize tissues
Sci. Agric. (Piracicaba, Braz.)
62
184-189
2005
Zea mays
-
Manually annotated by BRENDA team
Velasco, I.; Arevalo-Rodriguez, M.; Marina, P.; Calderon, I.L.
A new mutation in the yeast aspartate kinase induces threonine accumulation in a temperature-regulated way
Yeast
22
99-110
2005
Saccharomyces cerevisiae, Saccharomyces cerevisiae (P10869), Saccharomyces cerevisiae HT1(pIVUts31d), Saccharomyces cerevisiae SG211
Manually annotated by BRENDA team
Cahyanto, M.N.; Kawasaki, H.; Nagashio, M.; Fujiyama, K.; Seki, T.
Regulation of aspartokinase, aspartate semialdehyde dehydrogenase, dihydrodipicolinate synthase and dihydrodipicolinate reductase in Lactobacillus plantarum
Microbiology
152
105-112
2006
Lactiplantibacillus plantarum, Lactiplantibacillus plantarum NCIMB 8826
Manually annotated by BRENDA team
Faehnle, C.R.; Liu, X.; Pavlovsky, A.; Viola, R.E.
The initial step in the archaeal aspartate biosynthetic pathway catalyzed by a monofunctional aspartokinase
Acta Crystallogr. Sect. F
62
962-966
2006
Methanocaldococcus jannaschii (Q57991), Methanocaldococcus jannaschii
Manually annotated by BRENDA team
Yoshida, A.; Tomita, T.; Kuzuyama, T.; Nishiyama, M.
Purification, crystallization and preliminary X-ray analysis of the regulatory subunit of aspartate kinase from Thermus thermophilus
Acta Crystallogr. Sect. F
63
96-98
2007
Thermus thermophilus (P61489), Thermus thermophilus
Manually annotated by BRENDA team
Ferreira, R.R.; Meinhardt, L.W.; Azevedo, R.A.
Lysine and threonine biosynthesis in sorghum seeds: characterisation of aspartate kinase and homoserine dehydrogenase isoenzymes
Ann. Appl. Biol.
149
77-86
2006
Sorghum bicolor
Manually annotated by BRENDA team
Hamano, Y.; Nicchu, I.; Shimizu, T.; Onji, Y.; Hiraki, J.; Takagi, H.
varepsilon-Poly-L-lysine producer, Streptomyces albulus, has feedback-inhibition resistant aspartokinase
Appl. Microbiol. Biotechnol.
76
873-882
2007
Streptomyces albulus, Streptomyces albulus (Q0KJ33), Streptomyces albulus CR1, Streptomyces albulus CR1 (Q0KJ33)
Manually annotated by BRENDA team
Nishida, H.; Narumi, I.
Phylogenetic and disruption analyses of aspartate kinase of Deinococcus radiodurans
Biosci. Biotechnol. Biochem.
71
1015-1020
2007
Deinococcus radiodurans, Deinococcus radiodurans (Q9RUL9), Deinococcus radiodurans R1 / ATCC 13939 / DSM 20539, Deinococcus radiodurans R1 / ATCC 13939 / DSM 20539 (Q9RUL9)
Manually annotated by BRENDA team
Curien, G.; Laurencin, M.; Robert-Genthon, M.; Dumas, R.
Allosteric monofunctional aspartate kinases from Arabidopsis
FEBS J.
274
164-176
2007
Arabidopsis thaliana, Arabidopsis thaliana (O23653), Arabidopsis thaliana (Q9LYU8), Arabidopsis thaliana (Q9S702)
Manually annotated by BRENDA team
Kotaka, M.; Ren, J.; Lockyer, M.; Hawkins, A.R.; Stammers, D.K.
Structures of R- and T-state Escherichia coli aspartokinase III. Mechanisms of the allosteric transition and inhibition by lysine
J. Biol. Chem.
281
31544-31552
2006
Escherichia coli
Manually annotated by BRENDA team
Wang, X.; Lopez-Valenzuela, J.A.; Gibbon, B.C.; Gakiere, B.; Galili, G.; Larkins, B.A.
Characterization of monofunctional aspartate kinase genes in maize and their relationship with free amino acid content in the endosperm
J. Exp. Bot.
58
2653-2660
2007
Zea mays, Zea mays (B0L9J2)
Manually annotated by BRENDA team
Yoshida, A.; Tomita, T.; Kurihara, T.; Fushinobu, S.; Kuzuyama, T.; Nishiyama, M.
Structural Insight into concerted inhibition of alpha 2 beta 2-type aspartate kinase from Corynebacterium glutamicum
J. Mol. Biol.
368
521-536
2007
Corynebacterium glutamicum, Corynebacterium glutamicum (P26512)
Manually annotated by BRENDA team
Hacham, Y.; Matityahu, I.; Schuster, G.; Amir, R.
Overexpression of mutated forms of aspartate kinase and cystathionine gamma-synthase in tobacco leaves resulted in the high accumulation of methionine and threonine
Plant J.
54
260-271
2008
Nicotiana tabacum
Manually annotated by BRENDA team
Liu, X.; Pavlovsky, A.G.; Viola, R.E.
The structural basis for allosteric inhibition of a threonine-sensitive aspartokinase
J. Biol. Chem.
283
16216-16225
2008
Methanocaldococcus jannaschii (Q57991), Methanocaldococcus jannaschii
Manually annotated by BRENDA team
Yoshida, A.; Tomita, T.; Kono, H.; Fushinobu, S.; Kuzuyama, T.; Nishiyama, M.
Crystal structures of the regulatory subunit of Thr-sensitive aspartate kinase from Thermus thermophilus
FEBS J.
276
3124-3136
2009
Thermus thermophilus (P61489), Thermus thermophilus
Manually annotated by BRENDA team
Lo, C.C.; Bonner, C.A.; Xie, G.; DSouza, M.; Jensen, R.A.
Cohesion group approach for evolutionary analysis of aspartokinase, an enzyme that feeds a branched network of many biochemical pathways
Microbiol. Mol. Biol. Rev.
73
594-651
2009
Aquifex aeolicus, Bdellovibrio bacteriovorus, Saccharomyces cerevisiae, Chlamydia sp., Escherichia coli, Leptospira interrogans, Methanopyrus kandleri, Myxococcus xanthus, Pyrococcus furiosus, Thermotoga maritima, Maricaulis maris, Thermotoga petrophila, Francisella tularensis subsp. novicida, Leptospira borgpetersenii, Corynebacterium glutamicum (P26512), Francisella tularensis subsp. novicida U112, Maricaulis maris MCS10, Bdellovibrio bacteriovorus HD100
Manually annotated by BRENDA team
Schuldt, L.; Suchowersky, R.; Veith, K.; Mueller-Dieckmann, J.; Weiss, M.S.
Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of the regulatory domain of aspartokinase (Rv3709c) from Mycobacterium tuberculosis
Acta Crystallogr. Sect. F
67
380-385
2011
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Stoeveken, N.; Pittelkow, M.; Sinner, T.; Jensen, R.A.; Heider, J.; Bremer, E.
A specialized aspartokinase enhances the biosynthesis of the osmoprotectants ectoine and hydroxyectoine in Pseudomonas stutzeri A1501
J. Bacteriol.
193
4456-4468
2011
Pseudomonas stutzeri
Manually annotated by BRENDA team
Yoshida, A.; Tomita, T.; Kuzuyama, T.; Nishiyama, M.
Mechanism of concerted inhibition of alpha2beta2-type hetero-oligomeric aspartate kinase from Corynebacterium glutamicum
J. Biol. Chem.
285
27477-27486
2010
Corynebacterium glutamicum
Manually annotated by BRENDA team
Chen, Z.; Rappert, S.; Sun, J.; Zeng, A.P.
Integrating molecular dynamics and co-evolutionary analysis for reliable target prediction and deregulation of the allosteric inhibition of aspartokinase for amino acid production
J. Biotechnol.
154
248-254
2011
Escherichia coli
Manually annotated by BRENDA team
Robin, A.Y.; Cobessi, D.; Curien, G.; Robert-Genthon, M.; Ferrer, J.L.; Dumas, R.
A new mode of dimerization of allosteric enzymes with ACT domains revealed by the crystal structure of the aspartate kinase from Cyanobacteria
J. Mol. Biol.
399
283-293
2010
Synechocystis sp. (P74569)
Manually annotated by BRENDA team
Qi, Q.; Huang, J.; Crowley, J.; Ruschke, L.; Goldman, B.S.; Wen, L.; Rapp, W.D.
Metabolically engineered soybean seed with enhanced threonine levels: biochemical characterization and seed-specific expression of lysine-insensitive variants of aspartate kinases from the enteric bacterium Xenorhabdus bovienii
Plant Biotechnol. J.
9
193-204
2011
Xenorhabdus bovienii
Manually annotated by BRENDA team
Ufaz, S.; Shukla, V.; Soloveichik, Y.; Golan, Y.; Breuer, F.; Koncz, Z.; Galili, G.; Koncz, C.; Zilberstein, A.
Transcriptional control of aspartate kinase expression during darkness and sugar depletion in Arabidopsis: involvement of bZIP transcription factors
Planta
233
1025-1040
2011
Arabidopsis thaliana
Manually annotated by BRENDA team
Yang, Q.; Yu, K.; Yan, L.; Li, Y.; Chen, C.; Li, X.
Structural view of the regulatory subunit of aspartate kinase from Mycobacterium tuberculosis
Protein Cell
2
745-754
2011
Mycobacterium tuberculosis (P9WPX3), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WPX3)
Manually annotated by BRENDA team
Rastegari, H.; Chiani, M.; Akbarzadeh, A.; Cheraghi, S.; Saffari, Z.; Mehrabi, M.; Farhangi, A.; Ghassemi, S.
Improvement in the production of L-lysine by overexpression of aspartokinase (ASK) in C. glutamicum ATCC 21799
Trop. J. Pharm. Res.
12
51-56
2013
Corynebacterium glutamicum
-
Manually annotated by BRENDA team
Viswanath, B.; Rajagopal, S.; Basha, P.; Rao, D.; Begum, P.; Rajakumari, D.; Razak, M.
Enhancing the activity of aspartate kinase for an overproduction of L-lysine by Corynebacterium glutamicum
Am. J. Biochem. Mol. Biol.
6
33-44
2016
Corynebacterium glutamicum (P26512), Corynebacterium glutamicum ATCC 13032 (P26512)
-
Manually annotated by BRENDA team
Wang, J.; Gao, D.; Yu, X.; Li, W.; Qi, Q.
Evolution of a chimeric aspartate kinase for L-lysine production using a synthetic RNA device
Appl. Microbiol. Biotechnol.
99
8527-8536
2015
Bacillus subtilis (P08495), Bacillus subtilis, Thermus thermophilus (P61489), Thermus thermophilus, Bacillus subtilis 168 (P08495)
Manually annotated by BRENDA team
Manjasetty, B.A.; Chance, M.R.; Burley, S.K.; Panjikar, S.; Almo, S.C.
Crystal structure of Clostridium acetobutylicum aspartate kinase (CaAK): an important allosteric enzyme for amino acids production
Biotechnol. Rep.
3
73-85
2014
Clostridium acetobutylicum (Q97MC0), Clostridium acetobutylicum
Manually annotated by BRENDA team
Min, W.; Li, H.; Li, H.; Liu, C.; Liu, J.
Characterization of Aspartate Kinase from Corynebacterium pekinense and the Critical Site of Arg169
Int. J. Mol. Sci.
16
28270-28284
2015
Corynebacterium pekinense (E0AE72), Corynebacterium pekinense
Manually annotated by BRENDA team
Dong, X.; Zhao, Y.; Zhao, J.; Wang, X.
Characterization of aspartate kinase and homoserine dehydrogenase from Corynebacterium glutamicum IWJ001 and systematic investigation of L-isoleucine biosynthesis
J. Ind. Microbiol. Biotechnol.
43
873-885
2016
Corynebacterium glutamicum, Corynebacterium glutamicum ATCC 13869
Manually annotated by BRENDA team
Clark, T.J.; Lu, Y.
Analysis of loss-of-function mutants in aspartate kinase and homoserine dehydrogenase genes points to complexity in the regulation of aspartate-derived amino acid contents
Plant Physiol.
168
1512-1526
2015
Arabidopsis thaliana (O23653), Arabidopsis thaliana (O81852), Arabidopsis thaliana (Q9LYU8), Arabidopsis thaliana (Q9S702), Arabidopsis thaliana (Q9SA18)
Manually annotated by BRENDA team
Tong, Z.; Xie, C.; Ma, L.; Liu, L.; Jin, Y.; Dong, J.; Wang, T.
Co-expression of bacterial aspartate kinase and adenylylsulfate reductase genes substantially increases sulfur amino acid levels in transgenic alfalfa (Medicago sativa L.)
PLoS ONE
9
e88310
2014
Escherichia coli (P08660)
Manually annotated by BRENDA team
Xu, J.; Han, M.; Ren, X.; Zhang, W.
Modification of aspartokinase III and dihydrodipicolinate synthetase increases the production of L-lysine in Escherichia coli
Biochem. Eng. J.
114
79-86
2016
Escherichia coli (P08660), Escherichia coli LATR11 (P08660)
-
Manually annotated by BRENDA team
Liu, P.; Zhang, B.; Yao, Z.H.; Liu, Z.Q.; Zheng, Y.G.
Multiplex design of the metabolic network for production of L-homoserine in Escherichia coli
Appl. Environ. Microbiol.
86
e01477-20
2020
Escherichia coli (P00561), Escherichia coli W3110 (P00561)
Manually annotated by BRENDA team
Li, C.C.; Yang, M.J.; Liu, L.; Li, T.; Peng, C.T.; He, L.H.; Song, Y.J.; Zhu, Y.B.; Shen, Y.L.; Yang, J.; Zhao, N.L.; Zhao, C.; Zhou, Q.X.; Li, H.; Kang, M.; Tong, A.P.; Tang, H.; Bao, R.
Mechanistic insights into the allosteric regulation of Pseudomonas aeruginosa aspartate kinase
Biochem. J.
475
1107-1119
2018
Pseudomonas aeruginosa (O69077)
Manually annotated by BRENDA team
Tsujimoto, M.; Yoshida, A.; Shimizu, T.; Tomita, T.; Ohnishi, Y.; Kuzuyama, T.; Nishiyama, M.
Aspartate kinase involved in 4-hydroxy-3-nitrosobenzamide biosynthesis in Streptomyces murayamaensis
Biosci. Biotechnol. Biochem.
80
2255-2263
2016
Streptomyces murayamaensis
Manually annotated by BRENDA team
Ohshida, T.; Koba, K.; Hayashi, J.; Yoneda, K.; Ohmori, T.; Ohshima, T.; Sakuraba, H.
A novel bifunctional aspartate kinase-homoserine dehydrogenase from the hyperthermophilic bacterium, Thermotoga maritima
Biosci. Biotechnol. Biochem.
82
2084-2093
2018
Thermotoga maritima, Thermotoga maritima (Q9WZ17), Thermotoga maritima DSM 3109 (Q9WZ17), Thermotoga maritima ATCC 43589 (Q9WZ17), Thermotoga maritima JCM 10099 (Q9WZ17)
Manually annotated by BRENDA team
Han, C.; Fang, L.; Liu, C.; Gao, Y.; Min, W.
Construction of novel aspartokinase mutant A380I and its characterization by molecular dynamics simulation
Molecules
23
3379
2018
Corynebacterium pekinense
Manually annotated by BRENDA team
Yang, Q.Q.; Yu, W.H.; Wu, H.Y.; Zhang, C.Q.; Sun, S.S.; Liu, Q.Q.
Lysine biofortification in rice by modulating feedback inhibition of aspartate kinase and dihydrodipicolinate synthase
Plant Biotechnol. J.
19
490-501
2021
Oryza sativa Japonica Group (Q5JK18)
Manually annotated by BRENDA team
Han, C.; Liu, S.; Liu, C.; Xie, X.; Fang, L.; Min, W.
The mutant T379L of novel aspartokinase from Corynebacterium pekinense A combined experimental and molecular dynamics simulation study
Process Biochem.
83
77-85
2019
Corynebacterium pekinense
-
Manually annotated by BRENDA team
Gao, Y.; Han, C.; Liu, C.; Wang, J.; Zhao, L.; Fang, L.; Min, W.
Enzymatic characterization and molecular mechanism of a novel aspartokinase mutant M372I/T379W from Corynebacterium pekinense
RSC Adv.
9
21344-21354
2019
Corynebacterium pekinense, Corynebacterium pekinense ATCC 13032
-
Manually annotated by BRENDA team
Wei, Z.; Han, C.; Gao, Y.; Fan, Z.; Wang, Y.; Wang, Z.; Min, W.
Construction and enzymatic characterization of novel aspartokinase mutant Y198N/D201M from Corynebacterium pekinense
Sh. Kexue/Food Sci.
41
127-133
2020
Corynebacterium pekinense
-
Manually annotated by BRENDA team