Reference on EC 2.7.4.7 - phosphooxymethylpyrimidine kinase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kim, Y.S.; Nosaka, K.; Downs, D.M.; Kwak, J.M.; Park, D.; Chung, I.K.; Nam, H.G.
A Brassica cDNA clone encoding a bifunctional hydroxymethylpyrimidine kinase/thiamin-phosphate pyrophosphorylase involved in thiamin biosynthesis
Plant Mol. Biol.
37
955-966
1998
Brassica napus (O48881)
Lewin, L.M.; Brown, G.M.
The biosynthesis of thiamine. III. Mechanism of enzymatic formation of the pyrophosphate ester of 2-methyl-4-amino-5-hydroxymethylpyrimidine
J. Biol. Chem.
236
2768-2771
1961
Saccharomyces cerevisiae
-
Reddick, J.J.; Kinsland, C.; Nicewonger, R.; Christian, T.; Downs, D.M.; Winkler, M.E.; Begley, T.P.
Overexpression, purification and characterization of two pyrimidine kinases involved in the biosynthesis of thiamin: 4-amino-5-hydroxymethyl-2-methylpyrimidine kinase and 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase
Tetrahedron
54
15983-15991
1998
Escherichia coli
-
Cheng, G.; Bennett, E.M.; Begley, T.P.; Ealick, S.E.
Crystal structure of 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase from Salmonella typhimurium at 2.3.ANG. resolution
Structure
10
225-235
2002
Salmonella enterica subsp. enterica serovar Typhimurium
Haas, A.L.; Laun, N.P.; Begley, T.P.
Thi20, a remarkable enzyme from Saccharomyces cerevisiae with dual thiamin biosynthetic and degradation activities
Bioorg. Chem.
33
338-344
2005
Saccharomyces cerevisiae (Q08224)
Kawasaki, Y.; Onozuka, M.; Mizote, T.; Nosaka, K.
Biosynthesis of hydroxymethylpyrimidine pyrophosphate in Saccharomyces cerevisiae
Curr. Genet.
47
156-162
2005
Saccharomyces cerevisiae
Onozuka, M.; Konno, H.; Kawasaki, Y.; Akaji, K.; Nosaka, K.
Involvement of thiaminase II encoded by the THI20 gene in thiamin salvage of Saccharomyces cerevisiae
FEMS Yeast Res.
8
266-275
2008
Saccharomyces cerevisiae (Q08224)
French, J.B.; Begley, T.P.; Ealick, S.E.
Structure of trifunctional THI20 from yeast
Acta Crystallogr. Sect. D
67
784-791
2011
Saccharomyces cerevisiae (Q08224)
Nodwell, M.B.; Menz, H.; Kirsch, S.F.; Sieber, S.A.
Rugulactone and its analogues exert antibacterial effects through multiple mechanisms including inhibition of thiamine biosynthesis
ChemBioChem
13
1439-1446
2012
Staphylococcus aureus (P66915)
Cea, P.A.; Araya, G.; Vallejos, G.; Recabarren, R.; Alzate-Morales, J.; Babul, J.; Guixe, V.; Castro-Fernandez, V.
Characterization of hydroxymethylpyrimidine phosphate kinase from mesophilic and thermophilic bacteria and structural insights into their differential thermal stability
Arch. Biochem. Biophys.
688
108389
2020
Salmonella enterica subsp. enterica serovar Typhimurium (P55882), Salmonella enterica subsp. enterica serovar Typhimurium, Thermus thermophilus (Q5SKG3), Thermus thermophilus, Salmonella enterica subsp. enterica serovar Typhimurium SGSC1412 (P55882), Salmonella enterica subsp. enterica serovar Typhimurium ATCC 700720 (P55882), Thermus thermophilus DSM 579 (Q5SKG3), Thermus thermophilus ATCC 27634 (Q5SKG3)
Thamm, A.M.; Li, G.; Taja-Moreno, M.; Gerdes, S.Y.; de Crecy-Lagard, V.; Bruner, S.D.; Hanson, A.D.
A strictly monofunctional bacterial hydroxymethylpyrimidine phosphate kinase precludes damaging errors in thiamin biosynthesis
Biochem. J.
474
2887-2895
2017
Campylobacter concisus (A7ZG21), Escherichia coli (P76422), Sulfurimonas denitrificans (Q30NV2), Sulfurimonas denitrificans DSM 1251 (Q30NV2), Campylobacter concisus 13826 (A7ZG21), Sulfurimonas denitrificans ATCC 33889 (Q30NV2), Escherichia coli BW25113 (P76422)
Hwang, S.; Cordova, B.; Abdo, M.; Pfeiffer, F.; Maupin-Furlow, J.
ThiN as a versatile domain of transcriptional repressors and catalytic enzymes of thiamine biosynthesis
J. Bacteriol.
199
e00810-16
2017
Haloferax volcanii (D4GV38), Haloferax volcanii NCIMB 2012 (D4GV38), Haloferax volcanii JCM 8879 (D4GV38), Haloferax volcanii DS2 (D4GV38), Haloferax volcanii DSM 3757 (D4GV38), Haloferax volcanii ATCC 29605 (D4GV38), Haloferax volcanii NBRC 14742 (D4GV38), Haloferax volcanii VKM B-1768 (D4GV38)
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