Information on EC 2.7.7.32 - galactose-1-phosphate thymidylyltransferase

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The expected taxonomic range for this enzyme is: Enterococcus faecalis

EC NUMBER
COMMENTARY hide
2.7.7.32
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RECOMMENDED NAME
GeneOntology No.
galactose-1-phosphate thymidylyltransferase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
dTTP + alpha-D-galactose 1-phosphate = diphosphate + dTDP-galactose
show the reaction diagram
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
nucleotidyl group transfer
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-
-
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SYSTEMATIC NAME
IUBMB Comments
dTTP:alpha-D-galactose-1-phosphate thymidylyltransferase
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CAS REGISTRY NUMBER
COMMENTARY hide
9023-25-0
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
dTTP + alpha-D-galactose 1-phosphate
dTDPgalactose + ?
show the reaction diagram
-
-
-
?
additional information
?
-
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involved in biosynthesis of cell wall constituents in Streptococcus faecalis
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-
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NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
additional information
?
-
-
involved in biosynthesis of cell wall constituents in Streptococcus faecalis
-
-
-
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6.5 - 7.5
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pH 6.5: 70% of maximal activity, pH 7.5: 60% of maximal activity at pH 7.5
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
80000 - 100000
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sucrose density gradient centrifugation
pH STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6 - 8
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complete inactivation outside this range
642820
STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
3°C, 50% loss of activity after 2 days, 80% loss of activity after 7 days, and 95% loss of activity after 16 days
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Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE