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Literature summary for 1.1.1.1 extracted from

  • Park, Y.C.; San, K.Y.; Bennett, G.N.
    Characterization of alcohol dehydrogenase 1 and 3 from Neurospora crassa FGSC2489 (2007), Appl. Microbiol. Biotechnol., 76, 349-356.
    View publication on PubMed
Search for more literature for 1.1.1.1

Cloned(Commentary)

Cloned (Comment) Organism
ADH1 is expressed in recombinant Escherichia coli Neurospora crassa
ADH3 is expressed in recombinant Escherichia coli Neurospora crassa

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
37443
-
 x * 37443, ADH1, calculated from sequence Neurospora crassa
37983
-
 x * 37983, ADH3, calculated from sequence Neurospora crassa

Organism

Organism UniProt Comment Textmining
Neurospora crassa
-
 FGSC2489
-
Neurospora crassa Q9P6C8 FGSC2489
-
Neurospora crassa DSM 1257 Q9P6C8 FGSC2489
-
Neurospora crassa FGSC2489
-
 FGSC2489
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-butanol + NAD+ about 80% of activity with ethanol, ADH1 Neurospora crassa butanal + NADH + H+
-
 ?
1-butanol + NAD+ about 80% of activity with ethanol, ADH1 Neurospora crassa DSM 1257 butanal + NADH + H+
-
 ?
1-hexanol + NAD+ about 90% of activity with ethanol, ADH1 Neurospora crassa hexanal + NADH + H+
-
 ?
1-hexanol + NAD+ about 90% of activity with ethanol, ADH1 Neurospora crassa DSM 1257 hexanal + NADH + H+
-
 ?
1-octanol + NAD+ about 85% of activity with ethanol, ADH1 Neurospora crassa octanal + NADH + H+
-
 ?
1-pentanol + NAD+ about 85% of activity with ethanol, ADH1 Neurospora crassa pentanal + NADH + H+
-
 ?
1-propanol + NAD+ about 75% of activity with ethanol, ADH1 Neurospora crassa propanal + NADH + H+
-
 ?
2-butanol + NAD+ about 25% of activity with ethanol, ADH1 Neurospora crassa 2-butanone + NADH + H+
-
 ?
2-propanol + NAD+ about 50% of activity with ethanol, ADH1 Neurospora crassa acetone + NADH + H+
-
 ?
2-propanol + NAD+ about 50% of activity with ethanol, ADH1 Neurospora crassa DSM 1257 acetone + NADH + H+
-
 ?
ethanol + NAD+
-
 Neurospora crassa acetaldehyde + NADH
-
 ?
ethanol + NAD+
-
 Neurospora crassa DSM 1257 acetaldehyde + NADH
-
 ?
additional information ADH1 preferrs primary alcohols containing C3-C8 carbons to secondary alcohols such as 2-propanol and 2-butanol. ADH1 possesses specific carboxylate ester-forming activity Neurospora crassa ?
-
 ?
additional information ADH1 preferrs primary alcohols containing C3-C8 carbons to secondary alcohols such as 2-propanol and 2-butanol. ADH1 possesses specific carboxylate ester-forming activity Neurospora crassa DSM 1257 ?
-
 ?

Subunits

Subunits Comment Organism
? x * 37443, ADH1, calculated from sequence Neurospora crassa
? x * 37983, ADH3, calculated from sequence Neurospora crassa

Synonyms

Synonyms Comment Organism
ADH1
-
 Neurospora crassa
ADH3
-
 Neurospora crassa

Cofactor

Cofactor Comment Organism Structure
NAD+ ADH1 preferrs NAD+ 205fold better than NADP+ as cofactor Neurospora crassa
NAD+ ADH3 does not react with NADP+ Neurospora crassa

pI Value

Organism Comment pI Value Maximum pI Value
Neurospora crassa calculated from sequence, ADH1
-
 6.3
Neurospora crassa calculated from sequence
-
 8.3