Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.1 extracted from

  • Ostberg, L.J.; Stroemberg, P.; Hedberg, J.J.; Persson, B.; Hoeoeg, J.O.
    Analysis of mammalian alcohol dehydrogenase 5 (ADH5): Characterisation of rat ADH5 with comparisons to the corresponding human variant (2013), Chem. Biol. Interact., 202, 97-103.
    View publication on PubMed
Search for more literature for 1.1.1.1

Cloned(Commentary)

Cloned (Comment) Organism
expression of human ADH1 in an in vitro transcription/translation system, N-terminally GST-tagged ADH1 in COS cells and in Escherichia coli Homo sapiens
expression of rat ADH5 in an in vitro transcription/translation system, GFP-tagged ADH5 in COS cells, but no soluble ADH5 protein from heterologously expression in Escherichia coli cells with expression systems successfully used for other mammalian ADHs, including fused to glutathione-S-transferase Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
colon low expression level of ADH5 Rattus norvegicus
-
duodenum low expression level of ADH5 Rattus norvegicus
-
kidney high expression level of ADH5 Rattus norvegicus
-
additional information no expression of ADH5 in lung, epididymis, uterus, ovary, thymus, adrenal, small intestine, heart, eye, muscle, brain, testis, stomach, spleen, and liver Rattus norvegicus
-

Synonyms

Synonyms Comment Organism
ADH1
-
 Homo sapiens
ADH5
-
 Rattus norvegicus
alcohol dehydrogenase 1
-
 Homo sapiens
alcohol dehydrogenase 5
-
 Rattus norvegicus

General Information

General Information Comment Organism
additional information ADH1 molecular modeling and molecular dynamics simulations, and comparison to rat ADH5 enzyme, overview Homo sapiens
additional information ADH5 molecular modeling and molecular dynamics simulations, and comparison to human ADH1 enzyme, overview Rattus norvegicus