KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0051 | - |
NADPH | skin fibroblasts, normal cells | Homo sapiens | |
0.0054 | - |
NADPH | skin Zellwenger syndrome fibroblasts | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyldihydroxyacetone phosphate + NADPH | Homo sapiens | acyldihydroxyacetone phosphate pathway | 1-acyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
alkyldihydroxyacetone phosphate + NADPH + H+ | Homo sapiens | acyldihydroxyacetone phosphate pathway | 1-alkyl-sn-glycerol 3-phosphate + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
skin fibroblast | Zellweger syndrome cell lines GM0228 and GM4340 and normal control cells | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyldihydroxyacetone phosphate + NADPH | - |
Homo sapiens | 1-acyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
acyldihydroxyacetone phosphate + NADPH | acyldihydroxyacetone phosphate pathway | Homo sapiens | 1-acyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
alkyldihydroxyacetone phosphate + NADPH + H+ | - |
Homo sapiens | 1-alkyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
alkyldihydroxyacetone phosphate + NADPH + H+ | acyldihydroxyacetone phosphate pathway | Homo sapiens | 1-alkyl-sn-glycerol 3-phosphate + NADP+ | - |
? | |
hexadecyldihydroxyacetone phosphate + NADPH | - |
Homo sapiens | 1-hexadecyl-sn-glycerol 3-phosphate + NADP+ | - |
? |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
50 | - |
t1/2: 15 min, control fibroblasts, t1/2: 20 min, Zellweger syndrome fibroblasts | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | hydrogen from B-side of nicotinamide ring is transferred to reduce keto substrates | Homo sapiens |