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Literature summary for 1.1.1.117 extracted from
- D-Arabinose dehydrogenase and biosynthesis of erythroascorbic acid in Candida albicans (1996), Biochim. Biophys. Acta, 1297, 1-8.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Cu2+ | - |
Candida albicans |  |
| Fe2+ | - |
Candida albicans | |
| Hg2+ | - |
Candida albicans | |
| Mg2+ | - |
Candida albicans | |
| Mn2+ | - |
Candida albicans | |
| NADPH | competitive to NADP+ | Candida albicans | |
| Zn2+ | - |
Candida albicans | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0446 | - |
NADP+ | - |
Candida albicans | |
| 28.9 | - |
L-fucose | - |
Candida albicans | |
| 29.9 | - |
D-arabinose | - |
Candida albicans | |
| 37.1 | - |
L-Xylose | - |
Candida albicans | |
| 60 | - |
D-arabinose | - |
Candida albicans | |
| 91.3 | - |
L-galactose | - |
Candida albicans | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | - |
Candida albicans | 5737 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 41000 | - |
gel filtration | Candida albicans |
| 42000 | - |
1 * 42000, SDS-PAGE | Candida albicans |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-arabinose + NAD(P)+ | Candida albicans | - |
D-arabino-1,4-lactone + NAD(P)H | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Candida albicans | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Candida albicans |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-arabinose + NAD(P)+ | - |
Candida albicans | D-arabino-1,4-lactone + NAD(P)H | - |
? | |
| L-fucose + NADP+ | - |
Candida albicans | 6-deoxy-L-galactono-1,4-lactone + NADPH + H+ | - |
? | |
| L-galactose + NADP+ | - |
Candida albicans | L-galactono-1,4-lactone + NADPH + H+ | - |
? | |
| L-xylose + NADP+ | - |
Candida albicans | L-xylono-1,4-lactone + NADPH | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 42000, SDS-PAGE | Candida albicans |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
- |
Candida albicans |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
- |
Candida albicans |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADP+ | - |
Candida albicans | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0786 | - |
NADPH | - |
Candida albicans | |
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