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Literature summary for 1.1.1.133 extracted from

  • Elling, L.; Rupprath, C.; Gunther, N.; Romer, U.; Verseck, S.; Weingarten, P.; Drager, G.; Kirschning, A.; Piepersberg, W.
    An enzyme module system for the synthesis of dTDP-activated deoxysugars from dTMP and sucrose (2005), ChemBioChem, 6, 1423-1430.
    View publication on PubMed
Search for more literature for 1.1.1.133

Application

Application Comment Organism
synthesis development and evaluation of a modular system for large scale production of important dTDP-activated deoxyhexoses from dTMP and sucrose, overview Salmonella enterica

Cloned(Commentary)

Cloned (Comment) Organism
gene rmlD, expression in Escherichia coli strain BL21(DE3) Salmonella enterica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dTDP-6-deoxy-L-mannose + NADP+ Salmonella enterica biosynthetic pathway, overview dTDP-4-dehydro-6-deoxy-L-mannose + NADPH
-
 ?

Organism

Organism UniProt Comment Textmining
Salmonella enterica
-
 serovar typhimurium, LT2, gene rmlD
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dTDP-6-deoxy-L-mannose + NADP+
-
 Salmonella enterica dTDP-4-dehydro-6-deoxy-L-mannose + NADPH
-
 ?
dTDP-6-deoxy-L-mannose + NADP+ biosynthetic pathway, overview Salmonella enterica dTDP-4-dehydro-6-deoxy-L-mannose + NADPH
-
 ?

Synonyms

Synonyms Comment Organism
4-ketoreductase
-
 Salmonella enterica
RmlD
-
 Salmonella enterica

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Salmonella enterica

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.8
-
 assay at Salmonella enterica

Cofactor

Cofactor Comment Organism Structure
NADP+
-
 Salmonella enterica