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Literature summary for 1.1.1.145 extracted from

  • Durocher, F.; Sanchez, R.; Ricketts, M.L.; Labrie, Y.; Laudet, V.; Simard, J.
    Characterization of the guinea pig 3beta-hydroxysteroid dehydrogenase/DELTA5-DELTA4-isomerase expressed in the adrenal gland and gonads (2005), J. Steroid Biochem. Mol. Biol., 97, 289-298.
    View publication on PubMed
Search for more literature for 1.1.1.145

Cloned(Commentary)

Cloned (Comment) Organism
cloning of the cDNA encoding 3beta-HSD from an adrenal library, DNA and amino acid sequence determination and analysis, phylogenetic analysis Cavia porcellus

Organism

Organism UniProt Comment Textmining
Cavia porcellus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adrenal gland
-
 Cavia porcellus
-
gonad
-
 Cavia porcellus
-
ovary
-
 Cavia porcellus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dehydroepiandrosterone + NAD+
-
 Cavia porcellus ?
-
 ?
additional information trifunctional enzyme that also catalyzes the reaction of the DELTA-5-3-ketosteroid isomerase, EC 5.3.3.1, and of the 17beta-hydroxysteroid dehydrogenase type II, EC 1.1.1.51 Cavia porcellus ?
-
 ?
pregnenolone + NAD+
-
 Cavia porcellus progesterone + NADH + H+
-
 ?

Synonyms

Synonyms Comment Organism
3beta-HSD
-
 Cavia porcellus
3beta-hydroxysteroid dehydrogenase/DELTA5-DELTA4-isomerase
-
 Cavia porcellus

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Cavia porcellus