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Literature summary for 1.1.1.146 extracted from

  • Claus, R.; Wagner, A.; Lambert, T.
    Characterization of 11beta-hydroxysteroid dehydrogenase activity in testicular tissue of control and GnRH-immunized boars as a possible regulator of spermatogenesis (2005), Exp. Clin. Endocrinol. Diabetes, 113, 262-267.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cortisone + NADPH + H+ Sus scrofa isozyme 11beta-HSD1 catalyzes the forward reaction with cofactor NADPH cortisol + NADP+
-
ir
additional information Sus scrofa the enzyme plays a role in control of cortisol and spermatogenesis ?
-
?

Organism

Organism UniProt Comment Textmining
Sus scrofa Q95L61
-
-

Source Tissue

Source Tissue Comment Organism Textmining
testis isozyme expression analysis Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
isozyme activity in testicular tissue and glucocorticoid concentration, overview, isozyme activity in testicular tissue and glucocorticoid concentration, overview Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cortisone + NADPH + H+ isozyme 11beta-HSD1 catalyzes the forward reaction with cofactor NADPH Sus scrofa cortisol + NADP+
-
ir
additional information the enzyme plays a role in control of cortisol and spermatogenesis Sus scrofa ?
-
?

Synonyms

Synonyms Comment Organism
11beta-HSD 1
-
Sus scrofa

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Sus scrofa

Expression

Organism Comment Expression
Sus scrofa isozyme expression analysis additional information