Application | Comment | Organism |
---|---|---|
medicine | high-fat diet-induced obesity is accompanied by increased visceral fat preadipocyte differentiation in wild-type but not 11beta-HSD1 -/- mice | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adipose tissue | isoform 11beta-HSD1 is highly expressed in freshly isolated omental adipose stromal vascular cells, predominantly in preadipocytes. The enzxyme acts as an 11beta-reduxtase, reactivating glucocorticoids. Glucocorticoid reactivation is higher in intact mesenteric cells than in thigh and axillary depots | Mus musculus | - |
preadipocyte | isoform 11beta-HSD1 is highly expressed in freshly isolated omental adipose stromal vascular cells, predominantly in preadipocytes | Mus musculus | - |
vascular cell | - |
Mus musculus | - |