Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-chloro-N-(4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]carbonyl]benzyl)benzenesulfonamide | - |
Homo sapiens | |
2-chloro-N-(4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]carbonyl]benzyl)benzenesulfonamide | - |
Mus musculus | |
3-chloro-N-(4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]carbonyl]benzyl)-4-fluorobenzenesulfonamide | - |
Homo sapiens | |
3-chloro-N-(4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]carbonyl]benzyl)-4-fluorobenzenesulfonamide | - |
Mus musculus | |
3-chloro-N-(4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]carbonyl]benzyl)benzenesulfonamide | - |
Homo sapiens | |
3-chloro-N-(4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]carbonyl]benzyl)benzenesulfonamide | - |
Mus musculus | |
3-chloro-N-[4-(morpholin-4-ylcarbonyl)benzyl]benzenesulfonamide | - |
Homo sapiens | |
3-chloro-N-[4-(morpholin-4-ylcarbonyl)benzyl]benzenesulfonamide | - |
Mus musculus | |
3-chloro-N-[4-(piperidin-1-ylcarbonyl)benzyl]benzenesulfonamide | - |
Homo sapiens | |
3-chloro-N-[4-(piperidin-1-ylcarbonyl)benzyl]benzenesulfonamide | - |
Mus musculus | |
3-chloro-N-[4-(pyrrolidin-1-ylcarbonyl)benzyl]benzenesulfonamide | - |
Homo sapiens | |
3-chloro-N-[4-(pyrrolidin-1-ylcarbonyl)benzyl]benzenesulfonamide | - |
Mus musculus | |
3-chloro-N-[4-[(4-methylpiperazin-1-yl)carbonyl]benzyl]benzenesulfonamide | - |
Homo sapiens | |
3-chloro-N-[4-[(4-methylpiperazin-1-yl)carbonyl]benzyl]benzenesulfonamide | - |
Mus musculus | |
4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N,N-diethylbenzamide | - |
Homo sapiens | |
4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N,N-diethylbenzamide | - |
Mus musculus | |
4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-(tricyclo[3.3.1.13,7]dec-1-yl)benzamide | - |
Homo sapiens | |
4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-(tricyclo[3.3.1.13,7]dec-1-yl)benzamide | - |
Mus musculus | |
4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cycloheptyl-N-methylbenzamide | - |
Homo sapiens | |
4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cycloheptyl-N-methylbenzamide | - |
Mus musculus | |
4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cycloheptyl-N-propylbenzamide | - |
Homo sapiens | |
4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cycloheptyl-N-propylbenzamide | - |
Mus musculus | |
4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cycloheptylbenzamide | - |
Homo sapiens | |
4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cycloheptylbenzamide | - |
Mus musculus | |
4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cyclohexylbenzamide | - |
Homo sapiens | |
4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cyclohexylbenzamide | - |
Mus musculus | |
4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cyclopentylbenzamide | - |
Homo sapiens | |
4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cyclopentylbenzamide | - |
Mus musculus | |
4-chloro-N-(4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]carbonyl]benzyl)benzenesulfonamide | - |
Homo sapiens | |
4-chloro-N-(4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]carbonyl]benzyl)benzenesulfonamide | - |
Mus musculus | |
glycyrrhizic acid | - |
Homo sapiens | |
glycyrrhizic acid | - |
Mus musculus | |
N-(4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]carbonyl]benzyl)-3-(trifluoromethyl)benzenesulfonamide | - |
Homo sapiens | |
N-(4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]carbonyl]benzyl)-3-(trifluoromethyl)benzenesulfonamide | - |
Mus musculus | |
N-butyl-4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cycloheptylbenzamide | - |
Homo sapiens | |
N-butyl-4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cycloheptylbenzamide | - |
Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adipose tissue | - |
Mus musculus | - |
adipose tissue | - |
Homo sapiens | - |
liver | - |
Mus musculus | - |
liver | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cortisone + NADPH + H+ | - |
Mus musculus | cortisol + NADP+ | - |
? | |
cortisone + NADPH + H+ | - |
Homo sapiens | cortisol + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
11beta-hydroxysteroid dehydrogenase type 1 | - |
Mus musculus |
11beta-hydroxysteroid dehydrogenase type 1 | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000002 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | 4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cycloheptyl-N-methylbenzamide | |
0.000002 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | 4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cycloheptyl-N-propylbenzamide | |
0.000002 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cycloheptyl-N-propylbenzamide | |
0.000002 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | N-butyl-4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cycloheptylbenzamide | |
0.000008 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | glycyrrhizic acid | |
0.00001 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | glycyrrhizic acid | |
0.00001 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | 4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-(tricyclo[3.3.1.13,7]dec-1-yl)benzamide | |
0.000014 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-(tricyclo[3.3.1.13,7]dec-1-yl)benzamide | |
0.000015 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | 4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cycloheptylbenzamide | |
0.000047 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-butyl-4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cycloheptylbenzamide | |
0.000049 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cycloheptylbenzamide | |
0.000131 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | 3-chloro-N-[4-(piperidin-1-ylcarbonyl)benzyl]benzenesulfonamide | |
0.000302 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | 4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cyclohexylbenzamide | |
0.000395 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | 4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N,N-diethylbenzamide | |
0.000411 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cyclohexylbenzamide | |
0.00048 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | 3-chloro-N-[4-(pyrrolidin-1-ylcarbonyl)benzyl]benzenesulfonamide | |
0.000576 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | 3-chloro-N-(4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]carbonyl]benzyl)benzenesulfonamide | |
0.000638 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cycloheptyl-N-methylbenzamide | |
0.000647 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 3-chloro-N-[4-(piperidin-1-ylcarbonyl)benzyl]benzenesulfonamide | |
0.000732 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | 4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cyclopentylbenzamide | |
0.001024 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | 3-chloro-N-(4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]carbonyl]benzyl)-4-fluorobenzenesulfonamide | |
0.00113 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 2-chloro-N-(4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]carbonyl]benzyl)benzenesulfonamide | |
0.001208 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | N-(4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]carbonyl]benzyl)-3-(trifluoromethyl)benzenesulfonamide | |
0.001319 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | 3-chloro-N-[4-[(4-methylpiperazin-1-yl)carbonyl]benzyl]benzenesulfonamide | |
0.001404 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | 4-chloro-N-(4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]carbonyl]benzyl)benzenesulfonamide | |
0.001672 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 3-chloro-N-(4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]carbonyl]benzyl)benzenesulfonamide | |
0.001733 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 3-chloro-N-[4-(pyrrolidin-1-ylcarbonyl)benzyl]benzenesulfonamide | |
0.002106 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N,N-diethylbenzamide | |
0.002631 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 3-chloro-N-(4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]carbonyl]benzyl)-4-fluorobenzenesulfonamide | |
0.002698 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-chloro-N-(4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]carbonyl]benzyl)benzenesulfonamide | |
0.003379 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | 3-chloro-N-[4-(morpholin-4-ylcarbonyl)benzyl]benzenesulfonamide | |
0.005614 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | N-(4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]carbonyl]benzyl)-3-(trifluoromethyl)benzenesulfonamide | |
0.005843 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | 2-chloro-N-(4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]carbonyl]benzyl)benzenesulfonamide | |
0.008512 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 4-([[(3-chlorophenyl)sulfonyl]amino]methyl)-N-cyclopentylbenzamide | |
0.01449 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 3-chloro-N-[4-(morpholin-4-ylcarbonyl)benzyl]benzenesulfonamide | |
0.0159 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 3-chloro-N-[4-[(4-methylpiperazin-1-yl)carbonyl]benzyl]benzenesulfonamide |