Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane | competitive. Also inhibitory to isoform 11beta-HSD2 | Homo sapiens | |
2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane | competitive. Also inhibitory to isoform 11beta-HSD2 | Rattus norvegicus | |
methoxychlor | competitive. Not inhibitory to isoform 11beta-HSD2 | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Homo sapiens | - |
- |
microsome | - |
Rattus norvegicus | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P28845 | - |
- |
Rattus norvegicus | P16232 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
testis | - |
Rattus norvegicus | - |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00191 | - |
37°C, pH not specified in the publication, microsomal assay | Homo sapiens | methoxychlor | |
0.00888 | - |
37°C, pH not specified in the publication, microsomal assay | Homo sapiens | 2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane | |
0.00915 | - |
37°C, pH not specified in the publication, microsomal assay | Rattus norvegicus | 2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane |