Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | the enzyme activity is not affected by laminar shear stress in endothelial cells, overview | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | the enzyme activity is not affected by laminar shear stress in endothelial cells, overview | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
6-pyruvoyl-5,6,7,8-tetrahydropterin + NADPH | Homo sapiens | - |
tetrahydrobiopterin + NADP+ | - |
r | |
additional information | Homo sapiens | the enzyme catalyzes the final step in the tetrahydrobiopterin biosynthesis | ? | - |
? | |
sepiapterin + NADPH + H+ | Homo sapiens | - |
7,8-dihydrobiopterin + NADP+ | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epithelial cell | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
6-pyruvoyl-5,6,7,8-tetrahydropterin + NADPH | - |
Homo sapiens | tetrahydrobiopterin + NADP+ | - |
r | |
additional information | the enzyme catalyzes the final step in the tetrahydrobiopterin biosynthesis | Homo sapiens | ? | - |
? | |
sepiapterin + NADPH + H+ | - |
Homo sapiens | 7,8-dihydrobiopterin + NADP+ | - |
r |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Homo sapiens | |
NADPH | - |
Homo sapiens |