Inhibitors | Comment | Organism | Structure |
---|---|---|---|
N-acetylserotonin | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
6-pyruvoyl-5,6,7,8-tetrahydropterin + NADPH | Homo sapiens | - |
tetrahydrobiopterin + NADP+ | - |
r | |
additional information | Homo sapiens | sepiapterin or dihydrobiopterin are the precursors of the tetrahydrobiopterin-salvage pathway, enzyme activity and pathway regulation in vivo, overview | ? | - |
? | |
sepiapterin + NADPH + H+ | Homo sapiens | cellular uptake of sepiapterin across the cell membrane results in an efficient accumulation of tetrahydrobiopterin, sepiapterin relocates across the plasma membrane via two distinct paths, the slower path connects to the cytosolic compartment, overview | 7,8-dihydrobiopterin + NADP+ | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HeLa cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
6-pyruvoyl-5,6,7,8-tetrahydropterin + NADPH | - |
Homo sapiens | tetrahydrobiopterin + NADP+ | - |
r | |
additional information | sepiapterin or dihydrobiopterin are the precursors of the tetrahydrobiopterin-salvage pathway, enzyme activity and pathway regulation in vivo, overview | Homo sapiens | ? | - |
? | |
sepiapterin + NADPH + H+ | - |
Homo sapiens | 7,8-dihydrobiopterin + NADP+ | - |
r | |
sepiapterin + NADPH + H+ | cellular uptake of sepiapterin across the cell membrane results in an efficient accumulation of tetrahydrobiopterin, sepiapterin relocates across the plasma membrane via two distinct paths, the slower path connects to the cytosolic compartment, overview | Homo sapiens | 7,8-dihydrobiopterin + NADP+ | - |
r |