Activating Compound | Comment | Organism | Structure |
---|---|---|---|
2-mercaptoethanol | activation | Escherichia coli | |
dithiothreitol | activation | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ascorbic acid | - |
Escherichia coli | |
BaCl2 | - |
Escherichia coli | |
CoCl2 | - |
Escherichia coli | |
CuCl2 | - |
Escherichia coli | |
EDTA | - |
Escherichia coli | |
FeCl3 | - |
Escherichia coli | |
HgCl2 | - |
Escherichia coli | |
MgCl2 | - |
Escherichia coli | |
NH4Cl | - |
Escherichia coli | |
potassium oxalate | - |
Escherichia coli | |
Sodium citrate | - |
Escherichia coli | |
sodium lauryl sulfate | - |
Escherichia coli | |
Sodium perchlorate | - |
Escherichia coli | |
Sodium periodate | - |
Escherichia coli | |
Sodium persulfate | - |
Escherichia coli | |
Triton X-100 | - |
Escherichia coli | |
Tween | - |
Escherichia coli | |
ZnCl2 | - |
Escherichia coli |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
CaCl2 | activation | Escherichia coli | |
KCl | activation | Escherichia coli | |
MnCl2 | activation | Escherichia coli | |
NaCl | activation | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
45 | - |
deoxycholic acid or lithocholic acid | Escherichia coli |
450 | - |
- |
Escherichia coli |
2348 | - |
taurocholic acid | Escherichia coli |
2916 | - |
glycocholic acid | Escherichia coli |
3486 | - |
cholic acid | Escherichia coli |
3743 | - |
taurochenodeoxycholic acid | Escherichia coli |
3856 | - |
glycochenodeoxycholic acid | Escherichia coli |
4164 | - |
chenodeoxycholic acid | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
chenodeoxycholic acid + NAD(P)+ | i.e. 3alpha,7alpha-dihydroxy-5beta-cholan-24-oic acid | Escherichia coli | 3alpha-hydroxy-7-oxo-5beta-cholan-24-oic acid + NAD(P)H | - |
? | |
cholic acid + NAD(P)+ | - |
Escherichia coli | 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholan-24-oic acid + NADH | - |
? | |
glycochenodeoxycholic acid + NAD(P)+ | - |
Escherichia coli | N-[3alpha-hydroxy-7,24-dioxocholan-24-yl]glycine + NAD(P)H | - |
? | |
glycocholic acid + NAD+ | i.e. N-[3alpha,7alpha,12alpha-trihydroxy-24-oxocholan-24-yl]glycine | Escherichia coli | N-[3alpha,12alpha-dihydroxy-7,24-dioxo-5beta-cholan-24-yl]glycine + NADH | - |
? | |
taurochenodeoxycholic acid + NAD+ | - |
Escherichia coli | 2[[3alpha-hydroxy-7,24-dioxo-5beta-cholan-24-yl]amino]ethane sulfonic acid + NADH | - |
? | |
taurocholic acid + NAD+ | i.e. 2[[3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholan-24-yl]amino]ethane sulfonic acid | Escherichia coli | 2[[3alpha,12alpha-dihydroxy-7,24-dioxo-5beta-cholan-24-yl]amino]ethane sulfonic acid + NADH | - |
? |