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Literature summary for 1.1.1.184 extracted from

  • Oritani, H.; Deyashiki, Y.; Nakayama, T.; Hara, A.; Sawada, H.; Matsuura, K.; Bunai, Y.; Ohya, I.
    Purification and characterization of pig lung carbonyl reductase (1992), Arch. Biochem. Biophys., 292, 539-547.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Benzamide
-
Sus scrofa
pyrazole
-
Sus scrofa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
additional information
-
Sus scrofa

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
24000
-
4 * 24000, SDS-PAGE Sus scrofa
103000
-
gel filtration, SDS-PAGE Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lung ciliated cells, nonciliated bronchiolar cells, Type II alveolar pneumocytes, epithelial cells of the ducts of the bronchial gland Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-butanal + NADPH
-
Sus scrofa 1-butanol + NADP+
-
?
1-heptanal + NADPH
-
Sus scrofa 1-heptanol + NADP+
-
?
1-hexanal + NADPH
-
Sus scrofa 1-hexanol + NADP+
-
?
1-indanone + NADPH
-
Sus scrofa 1-indanol + NADP+
-
?
1-nonanal + NADPH
-
Sus scrofa 1-nonanol + NADP+
-
?
1-pentanal + NADPH
-
Sus scrofa 1-pentanol + NADP+
-
?
1-propanal + NADPH
-
Sus scrofa 1-propanol + NADP+
-
?
2-butanone + NADPH
-
Sus scrofa 2-butanol + NADP+
-
?
2-pentanone + NADPH
-
Sus scrofa 2-pentanol + NADP+
-
?
3-benzoylpyridine + NADPH
-
Sus scrofa ?
-
?
4-benzoylpyridine + NADPH
-
Sus scrofa ?
-
?
4-nitroacetophenone + NADPH
-
Sus scrofa ?
-
?
4-nitrobenzaldehyde + NADPH
-
Sus scrofa 4-nitrobenzyl alcohol + NADP+
-
?
5alpha-androstan-17beta-ol-3-one + NADPH
-
Sus scrofa ?
-
?
5alpha-androstane-3,17-dione + NADPH
-
Sus scrofa ?
-
?
5beta-androstan-17beta-ol-3-one + NADPH
-
Sus scrofa ?
-
?
5beta-androstane-3,17-dione + NADPH
-
Sus scrofa ?
-
?
acetone + NADPH
-
Sus scrofa propan-2-ol + NADP+
-
?
benzaldehyde + NADPH
-
Sus scrofa benzyl alcohol + NADP+
-
?
camphorquinone + NADPH + H+
-
Sus scrofa camphorquinol + NADP+
-
?
cyclohexanone + NADPH
-
Sus scrofa cyclohexanol + NADP+
-
?
decanal + NADPH
-
Sus scrofa decanol + NADP+
-
?
menadione + NADPH
-
Sus scrofa ?
-
?
additional information overview Sus scrofa ?
-
?
additional information NADH also acts as cofactor Sus scrofa ?
-
?
octanal + NADPH + H+
-
Sus scrofa 1-octanol + NADP+
-
?
pyridine-3-aldehyde + NADPH
-
Sus scrofa ?
-
?
pyridine-4-aldehyde + NADPH
-
Sus scrofa ?
-
?
testosterone + NADPH + H+
-
Sus scrofa ?
-
?

Subunits

Subunits Comment Organism
tetramer 4 * 24000, SDS-PAGE Sus scrofa

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5.8
-
-
Sus scrofa

Cofactor

Cofactor Comment Organism Structure
NADH
-
Sus scrofa
NADP+
-
Sus scrofa
NADPH pro-4S hydrogen atom of the nicotinamide ring of NADPH is transferred to the substrate Sus scrofa