Application | Comment | Organism |
---|---|---|
synthesis | production of carbonyl reductase by Candida viswanathii in 6.6 l fermentor, using controlled pH value at 8.0, aeration rate 1 vvm and an agitation speed of 250 rpm at 25°C. Use of enzyme for preparative scale reduction of N,N-dimethyl-3-keto-2-thienyl-propanamine to (S)-N,N-dimethyl-3-keto-2-thienyl-propanamine | Candida viswanathii |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Candida viswanathii | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N,N-dimethyl-3-keto-2-thienyl-propanamine + NADPH | - |
Candida viswanathii | (S)-N,N-dimethyl-3-keto-2-thienyl-propanamine + NADP+ | key intermediate in synthesis of (S)-duloxetine | ? |