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Literature summary for 1.1.1.2 extracted from

  • Van Iersel, M.F.; Eppink, M.H.; van Berkel, W.J.; Rombouts, F.M.; Abee, T.
    Purification and characterization of a novel NADP-dependent branched-chain alcohol dehydrogenase from Saccharomyces cerevisiae (1997), Appl. Environ. Microbiol., 63, 4079-4082.
    View publication on PubMedView publication on EuropePMC

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.16
-
pentanal coenzyme NADPH Saccharomyces cerevisiae
0.18
-
hexanal coenzyme NADPH Saccharomyces cerevisiae
0.21
-
3-Methylbutanal coenzyme NADPH Saccharomyces cerevisiae
0.27
-
Heptanal coenzyme NADPH Saccharomyces cerevisiae
0.83
-
hexanal coenzyme NADH Saccharomyces cerevisiae
1.22
-
Hexanol coenzyme NADPH Saccharomyces cerevisiae
1.69
-
trans-2-hexenol coenzyme NADPH Saccharomyces cerevisiae
1.85
-
2-methylbutanal coenzyme NADPH Saccharomyces cerevisiae
1.89
-
3-Methylbutanal coenzyme NADH Saccharomyces cerevisiae
2.76
-
Butanal coenzyme NADPH Saccharomyces cerevisiae
3.01
-
pentanal coenzyme NADH Saccharomyces cerevisiae
4.25
-
Heptanal coenzyme NADH Saccharomyces cerevisiae
17.7
-
2-methylbutanal coenzyme NADH Saccharomyces cerevisiae
23.1
-
Butanal coenzyme NADH Saccharomyces cerevisiae
27
-
propanal coenzyme NADH Saccharomyces cerevisiae
38.9
-
propanal coenzyme NADPH Saccharomyces cerevisiae
158
-
acetaldehyde
-
Saccharomyces cerevisiae

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
37000
-
gel filtration Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Acinetobacter calcoaceticus
-
-
-
Saccharomyces cerevisiae
-
yeast
-
Saccharomyces cerevisiae
-
var. uvarum W34
-

Purification (Commentary)

Purification (Comment) Organism
-
Saccharomyces cerevisiae
partial Acinetobacter calcoaceticus

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
61.6
-
-
Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-methylbutanal + NADPH
-
Saccharomyces cerevisiae 2-methylbutanol + NADP+
-
r
3-methylbutanal + NADPH
-
Saccharomyces cerevisiae 3-methylbutanol + NADP+
-
r
ethanol + NADP+
-
Saccharomyces cerevisiae acetaldehyde + NADPH + H+
-
?
hexanal + NADPH + H+
-
Saccharomyces cerevisiae hexanol + NADP+
-
r
n-heptanol + NADP+
-
Saccharomyces cerevisiae n-heptanal + NADPH
-
r
n-hexanol + NADP+
-
Saccharomyces cerevisiae n-hexanal + NADPH
-
r
pentanal + NADPH
-
Saccharomyces cerevisiae pentanol + NADP+
-
r
propanal + NADPH + H+
-
Saccharomyces cerevisiae propanol + NADP+
-
r
trans-2-hexenol + NADP+
-
Saccharomyces cerevisiae trans-2-hexenal + NADPH
-
r

Subunits

Subunits Comment Organism
monomer 1 * 37000, SDS-PAGE Saccharomyces cerevisiae