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Literature summary for 1.1.1.205 extracted from

  • Cooney, D.; Hamel, E.; Cohen, M.; Kang, G.J.; Dalal, M.; Marquez, V.
    A simple method for the rapid determination of the stereospecificity of NAD-dependent dehydrogenases applied to mammalian IMP dehydrogenase and bacterial NADH peroxidase (1987), Biochim. Biophys. Acta, 916, 89-93.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Escherichia coli
partial purification Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
lymphoblast
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
inosine 5'-phosphate + NAD+ + H2O
-
Mus musculus xanthosine 5'-phosphate + NADH
-
?
inosine 5'-phosphate + NAD+ + H2O
-
Escherichia coli xanthosine 5'-phosphate + NADH
-
?

Cofactor

Cofactor Comment Organism Structure
NAD+ B-sided stereospecificity: 2-3H of IMP is transferred to pro-S position of carbon atom C-4 of the nicotinamide ring in NAD+ Mus musculus
NAD+ B-sided stereospecificity: 2-3H of IMP is transferred to pro-S position of carbon atom C-4 of the nicotinamide ring in NAD+ Escherichia coli