Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5'-thio-IMP | competitive inhibitor | Klebsiella aerogenes | |
6-thioinosine 5'-phosphate | in absence of glutathione | Klebsiella aerogenes | |
xanthosine 5'-phosphate | product inhibitor | Klebsiella aerogenes |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.013 | - |
5'-mercapto-5'-deoxyinosine 5'-S-phosphate | - |
Klebsiella aerogenes | |
0.038 | - |
5'-Amino-5'-deoxyinosine 5'-N-phosphate | - |
Klebsiella aerogenes | |
0.21 | - |
Inosine 5'-phosphorothioate | - |
Klebsiella aerogenes |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Klebsiella aerogenes | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
IMP + NAD+ + H2O = XMP + NADH + H+ | enzyme acts on the hydroxyl group of the hydrated derivative of the substrate, ordered bi-bi mechanism | Klebsiella aerogenes |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5'-amino-5'-deoxyinosine 5'-N-phosphate + NAD+ + H2O | - |
Klebsiella aerogenes | 5'-amino-5'-deoxyxanthosine 5'-N-phosphate + NADH | - |
? | |
5'-mercapto-5'-deoxyinosine 5'-S-phosphate + NAD+ + H2O | - |
Klebsiella aerogenes | 5'-mercapto-5'-deoxyxanthosine 5'-phosphate + NADH | - |
? | |
inosine 5'-phosphate + NAD+ + H2O | - |
Klebsiella aerogenes | xanthosine 5'-phosphate + NADH | - |
? | |
inosine 5'-phosphorothioate + NAD+ + H2O | - |
Klebsiella aerogenes | xanthosine 5'-phosphorothioate + NADH | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Klebsiella aerogenes |