Inhibitors | Comment | Organism | Structure |
---|---|---|---|
6-Chloro-9-beta-D-ribofuranosylpurine 5 '-phosphate | - |
Rattus norvegicus | |
AMP | - |
Rattus norvegicus | |
GMP | - |
Rattus norvegicus | |
NAD+ | - |
Rattus norvegicus | |
p-chloromercuribenzoate | inhibition can be restored by addition of DTT | Rattus norvegicus | |
xanthosine 5'-phosphate | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
K+ | full activity in presence of K+ | Rattus norvegicus | |
Na+ | can partially replace K+ in activation | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
additional information | - |
enzyme tends to aggregate owing to its own physicochemical characteristics | Rattus norvegicus |
68000 | - |
2 * 68000, Yoshida sarcoma ascites tumor cells, SDS-PAGE | Rattus norvegicus |
127000 | - |
Yoshida sarcoma ascites tumor cells, gel filtration in presence of 10% (NH4)2SO4 | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Yoshida sarcoma ascites cells | - |
Purification (Comment) | Organism |
---|---|
homogeneitiy | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Yoshida ascites sarcoma cell | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
1.19 | - |
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
inosine 5'-phosphate + NAD+ + H2O | - |
Rattus norvegicus | xanthosine 5'-phosphate + NADH | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 68000, Yoshida sarcoma ascites tumor cells, SDS-PAGE | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.8 | 8 | - |
Rattus norvegicus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6.7 | 9 | pH 6.7: about 40% of activity maximum, pH 9.0: about 55% of activity maximum | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.109 | - |
xanthosine 5'-phosphate | - |
Rattus norvegicus | |
0.13 | - |
GMP | - |
Rattus norvegicus | |
0.854 | - |
AMP | - |
Rattus norvegicus |