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Literature summary for 1.1.1.205 extracted from

  • Carr, S.F.; Papp, E.; Wu, J.C.; Natsumeda, Y.
    Characterization of human type I and type II IMP dehydrogenases (1993), J. Biol. Chem., 36, 27286-27290.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Mycophenolic acid type II enzyme is 4.8fold more sensitive than type I Homo sapiens
NADH
-
Homo sapiens
xanthosine 5'-phosphate
-
Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
additional information
-
Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
56000
-
4 * 56000 density gradient centrifugation Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
type II
-

Subunits

Subunits Comment Organism
tetramer 4 * 56000 density gradient centrifugation Homo sapiens

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
additional information
-
additional information various substrates Homo sapiens
0.0217
-
NAD+ type II enzyme Homo sapiens
0.025
-
NAD+ type I enzyme Homo sapiens

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
additional information
-
additional information
-
Homo sapiens