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Literature summary for 1.1.1.206 extracted from

  • Rocha, P.; Stenzel, O.; Parr, A.; Walton, N.; Christou, P.; Drager, B.; Leech, M.J.
    Functional expression of tropinone reductase I (trI) and hyoscyamine-6beta-hydroxylase (h6h) from Hyoscyamus niger in Nicotiana tabacum (2002), Plant Sci., 162, 905-913.
No PubMed abstract available

Cloned(Commentary)

Cloned (Comment) Organism
cDNAs encoding two enzymes of tropane-alkaloid biosynthesis, tropinone reductase I and hyoscyamine-6beta-hydroxylase are simultaneously introduced into Nicotiana tabacum using particle bombardment and expressed under the control of the CaMV 35S promoter. The expression leads to the formation of unexpected substances, e.g. acetyltropine. Leaves of transgenic plants show in most cases higher nicotine content than leaves of control plants. In addition nicotine related compounds such as anatabine, nornicotine, bipyridine, anabasine, and myosmine are identified in transgenic tobacco lines and are below detection limit in wild-type plants Hyoscyamus niger

Organism

Organism UniProt Comment Textmining
Hyoscyamus niger
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Synonyms

Synonyms Comment Organism
TR-I
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Hyoscyamus niger
tropinone reductase I
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Hyoscyamus niger