Activating Compound | Comment | Organism | Structure |
---|---|---|---|
(NH4)2SO4 | 0.1 M | Homo sapiens | |
(NH4)2SO4 | 0.1 M | Rattus norvegicus | |
(NH4)2SO4 | wild type and recombinant from Escherichia coli | Homo sapiens | |
(NH4)2SO4 | wild type and recombinant from Escherichia coli | Rattus norvegicus | |
Na2SO4 | 0.1 M, wild type and recombinant from E.coli | Homo sapiens | |
Na2SO4 | 0.1 M, wild type and recombinant from E.coli | Rattus norvegicus |
Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Homo sapiens |
expression in Escherichia coli | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(S)-6-fluorospiro[chroman-4,5'-imidazolidine]-2',4'-dione | wild type and recombinant from E. coli | Homo sapiens | |
(S)-6-fluorospiro[chroman-4,5'-imidazolidine]-2',4'-dione | wild type and recombinant from E. coli | Rattus norvegicus | |
Cl- | 0.2 M, wild type and recombinant from E. coli | Homo sapiens | |
Cl- | 0.2 M, wild type and recombinant from E. coli | Rattus norvegicus | |
N-[[6-methoxy-5(trifluoromethyl)-1-naphthalenyl]thioxomethyl]-N-methylglycine | wild type and recombinant from E. coli | Homo sapiens | |
N-[[6-methoxy-5(trifluoromethyl)-1-naphthalenyl]thioxomethyl]-N-methylglycine | wild type and recombinant from E. coli | Rattus norvegicus | |
ponalrestat | wild type and recombinant from E. coli | Homo sapiens | |
ponalrestat | wild type and recombinant from E. coli | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.046 | - |
DL-glyceraldehyde | - |
Homo sapiens | |
0.047 | - |
DL-glyceraldehyde | recombinant from E. coli | Homo sapiens | |
0.08 | - |
DL-glyceraldehyde | - |
Rattus norvegicus | |
0.12 | - |
DL-glyceraldehyde | recombinant from E. coli | Rattus norvegicus | |
4.8 | - |
D-glucuronate | - |
Homo sapiens | |
6.4 | - |
D-glucuronate | recombinant from E. coli | Homo sapiens | |
8.2 | - |
D-xylose | - |
Homo sapiens | |
8.7 | - |
D-xylose | recombinant from E. coli | Homo sapiens | |
13.5 | - |
D-xylose | - |
Rattus norvegicus | |
13.9 | - |
D-glucuronate | recombinant from E. coli | Rattus norvegicus | |
16.8 | - |
D-xylose | recombinant from E. coli | Rattus norvegicus | |
19.2 | - |
D-glucuronate | - |
Rattus norvegicus | |
42.9 | - |
D-galactose | recombinant from E. coli | Homo sapiens | |
46.7 | - |
D-galactose | - |
Homo sapiens | |
78 | - |
D-galactose | recombinant from E. coli | Rattus norvegicus | |
83 | - |
D-galactose | - |
Rattus norvegicus | |
86.8 | - |
D-glucose | - |
Homo sapiens | |
98.1 | - |
D-glucose | recombinant from E. coli | Homo sapiens | |
204 | - |
D-glucose | - |
Rattus norvegicus | |
281 | - |
D-glucose | recombinant from E. coli | Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Li2SO4 | 0.1 M activation wild type and recombinant from E. coli | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
38000 | - |
? * 38000, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
wild type and expressed in Escherichia coli | Homo sapiens |
wild type and expressed in Escherichia coli | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lens | - |
Homo sapiens | - |
lens | - |
Rattus norvegicus | - |
placenta | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
alditol + NAD(P)+ | - |
Homo sapiens | aldose + NAD(P)H | - |
r | |
alditol + NAD(P)+ | - |
Rattus norvegicus | aldose + NAD(P)H | - |
r | |
aldose + NAD(P)H | - |
Homo sapiens | alditol + NAD(P)+ | - |
r | |
aldose + NAD(P)H | - |
Rattus norvegicus | alditol + NAD(P)+ | - |
r | |
D-galactose + NAD(P)H | - |
Homo sapiens | dulcitol + NAD(P)+ | - |
r | |
D-galactose + NAD(P)H | - |
Rattus norvegicus | dulcitol + NAD(P)+ | - |
r | |
D-glucose + NAD(P)H | - |
Homo sapiens | sorbitol + NAD(P)+ | - |
r | |
D-glucose + NAD(P)H | - |
Rattus norvegicus | sorbitol + NAD(P)+ | - |
r | |
D-glucuronate + NAD(P)H | - |
Homo sapiens | ? | - |
r | |
D-glucuronate + NAD(P)H | - |
Rattus norvegicus | ? | - |
r | |
D-xylose + NAD(P)H | - |
Homo sapiens | xylitol + NAD(P)+ | - |
r | |
D-xylose + NAD(P)H | - |
Rattus norvegicus | xylitol + NAD(P)+ | - |
r | |
DL-glyceraldehyde + NAD(P)H | - |
Homo sapiens | glycerol + NAD(P)+ | - |
r | |
DL-glyceraldehyde + NAD(P)H | - |
Rattus norvegicus | glycerol + NAD(P)+ | - |
r |
Subunits | Comment | Organism |
---|---|---|
More | ? * 38000, SDS-PAGE | Homo sapiens |