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Literature summary for 1.1.1.219 extracted from

  • Tian, J.; Han, Z.Y.; Zhang, J.; Hu, Y.; Song, T.; Yao, Y.
    The balance of expression of dihydroflavonol 4-reductase and flavonol synthase regulates flavonoid biosynthesis and red foliage coloration in crabapples (2015), Sci. Rep., 5, 12228.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene McDFR, relative enzyme expression analysis and quantitative RT-PCR enzyme expression analysis, transient overexpression of McDFR in leaves of cultivars Royalty and Flame. McDFR is overexpressed in fruits using the vector pBI121-McDFR Malus hybrid cultivar

Protein Variants

Protein Variants Comment Organism
additional information transient overexpression of McDFR gene in the stem tips of the evergreen cultivar Strawberry Jelly promotes anthocyanin accumulation and a deep green coloration in most of the new buds. Malus hybrid cultivar

Organism

Organism UniProt Comment Textmining
Malus hybrid cultivar C3UZH2 crabapple, cvs. Royalty and Flame
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Source Tissue

Source Tissue Comment Organism Textmining
leaf levels of anthocyanins and the transcript abundance of the anthocyanin biosynthetic gene, dihydroflavonol 4-reductase (McDFR) during the leaf development in two crabapple cultivars, overview. The concentrations of anthocyanins and flavonols correlate with leaf color and the expression of McDFR and McFLS influences their accumulation Malus hybrid cultivar
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Synonyms

Synonyms Comment Organism
DFR
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Malus hybrid cultivar
McDFR
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Malus hybrid cultivar

Expression

Organism Comment Expression
Malus hybrid cultivar the abundance of endogenous McDFR transcripts is greatly reduced in TRV-McDFR infected leaves down

General Information

General Information Comment Organism
malfunction overexpression of McDFR, or silencing of McFLS, increases anthocyanin production, resulting in red-leaf and red fruit peel phenotypes, while overexpression of McFLS, or silencing of McDFR, increase anthocyanin production, resulting in red-leaf and red fruit peel phenotypes Malus hybrid cultivar
metabolism dihydroflavonol 4-reductase, McDFR, and flavonol synthase, McFLS, are important determinants of the red color of crabapple leaves, via the regulation of the metabolic fate of substrates that these enzymes have in common. Flavonoid biosynthetic pathway in plant, overview Malus hybrid cultivar
physiological function McDFR expression is associated with red color formation in crabapple leaves. Concentrations of anthocyanins and flavonols correlate with leaf color, the expression of dihydroflavonol 4-reductase, McDFR, and flavonol synthase, McFLS, influences their accumulation. Enzyme McDFR is an important determinant of the red color of crabapple leaves. The relative activities of McDFR and McFLS are important determinants of the red color of crabapple leaves Malus hybrid cultivar