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Literature summary for 1.1.1.22 extracted from

  • Grubb, M.F.; Kasofsky, J.; Strong, J.; Anderson, L.W.; Cysyk, R.L.
    Serum stimulation of UDP-glucose dehydrogenase activity in swiss 3T3 fibroblasts (1993), Biochem. Mol. Biol. Int., 30, 819-827.
    View publication on PubMed
Search for more literature for 1.1.1.22

Activating Compound

Activating Compound Comment Organism Structure
additional information fetal calf serum stimulates enzyme activity Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
UDP-D-xylose
-
 Homo sapiens
UDPglucuronate product feed-back inhibition competitive with UDPglucose Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.108
-
 UDPglucose
-
 Homo sapiens
0.17
-
 NAD+
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDPglucose + NAD+ + H2O Homo sapiens
-
 UDPglucuronate + NADH
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast cell line enzyme activity depends on growth phase of the culture Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-glucose + 2 NAD+ + H2O
-
 Homo sapiens UDP-glucuronate + 2 NADH + 2 H+
-
 ?
UDPglucose + NAD+ + H2O
-
 Homo sapiens UDPglucuronate + NADH
-
 ?