Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.239 extracted from

  • Dumont, M.; Luu-The, V.; de Lanoit, Y.; Labrie, F.
    Expression of human 17beta-hydroxysteroid dehydrogenase in mammalian cells (1992), J. Steroid Biochem. Mol. Biol., 41, 605-608.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HeLa human cervical carcinoma cells and COS-1 monkey kidney tumor cells Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
testosterone + NAD+ Homo sapiens
-
androst-4-ene-3,17-dione + NADH + H+
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adipose
-
Homo sapiens
-
mammary gland
-
Homo sapiens
-
ovary
-
Homo sapiens
-
placenta
-
Homo sapiens
-
prostate gland
-
Homo sapiens
-
testis
-
Homo sapiens
-
uterine endometrium
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
11beta-hydroxytestosterone + NAD+
-
Homo sapiens 11beta-hydroxyandrost-4-ene-3,17-dione + NADH
-
r
estradiol + NAD+
-
Homo sapiens estrone + NADH
-
r
testosterone + NAD+
-
Homo sapiens androst-4-ene-3,17-dione + NADH + H+
-
?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Homo sapiens