Application | Comment | Organism |
---|---|---|
medicine | in patients with cryptorchid testis, AKR1C3 expression occurs in a Tanner stage dependent-fashion. Pre- and peri-pubertal changes appear to promote expression of the enzyme in Leydig cells. In contrast to the normal adult testis, the pediatric cryptorchid testis reveals AKR1C3 expression in Sertoli cells | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Leydig cell | pre- and peri-pubertal changes promote expression of the enzyme in Leydig cells | Homo sapiens | - |
additional information | in patients with cryptorchid testis, no AKR1C3 expression is seen in germ cells at any stage | Homo sapiens | - |
Sertoli cell | in contrast to the normal adult testis, the pediatric cryptorchid testis shows AKR1C3 expression in 18%-26% of Sertoli cells in patients at Tanner stages 2 and beyond | Homo sapiens | - |
testis | cryptorchid testis. AKR1C3 expression is identified at all ages in fibromyocytes surrounding the testicular tubules | Homo sapiens | - |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | AKR1C3 expression occurs in a Tanner stage dependent-fashion | additional information |