Literature summary for 1.1.1.267 extracted from

Radykewicz, T.; Rohdich, F.; Wungsintaweekul, J.; Herz, S.; Kis, K.; Eisenreich, W.; Bacher, A.; Zenk, M.H.; Arigoni, D.
Biosynthesis of terpenoids: 1-deoxy-D-xylulose-5-phosphate reductoisomerase from Escherichia coli is a class B dehydrogenase (2000), FEBS Lett., 465, 157-160.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1-deoxy-D-xylulose 5-phosphate + NADPH + H+	Escherichia coli	-	2-C-methyl-D-erythritol 4-phosphate + NADP+	-	ir

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Reaction

Reaction	Comment	Organism	Reaction ID
2-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+	stereochemistry	Escherichia coli	a

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1-deoxy-D-xylulose 5-phosphate + NADPH + H+	-	Escherichia coli	2-C-methyl-D-erythritol 4-phosphate + NADP+	-	ir

Cofactor

Cofactor	Comment	Organism	Structure
NADP+	-	Escherichia coli

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Release 2023.1 (January 2023)